Preliminary results a of large-scale validation study of a new neuropsychological screening instrument for identifying children with learning disabilities

1992 ◽  
Vol 7 (4) ◽  
pp. 362-362
Author(s):  
G.E. Shute ◽  
J. Sprock ◽  
J. Lowery-Hazlett ◽  
P. Olson ◽  
M. Ryan
2005 ◽  
Vol 5 (2) ◽  
pp. 1771-1796 ◽  
Author(s):  
G. van Soest ◽  
L. G. Tilstra ◽  
P. Stammes

Abstract. In this paper we present an extensive validation of calibrated SCIAMACHY nadir reflectance in the UV (240–400 nm) by comparison with spectra calculated with a fast radiative transfer model. We use operationally delivered near-real-time level 1 data, processed with 5 standard calibration tools. A total of 9 months of data has been analysed. This is the first reflectance validation study incorporating such a large amount of data. It is shown that this method is a valuable tool for spotting spatial and temporal anomalies. We conclude that SCIAMACHY reflectance data in this wavelength range are stable over the investigated period. In addition, we show an example of an 10 anomaly in the data due to an error in the processing chain that could be detected by our comparison. This validation method could be extremely useful too for validation of other satellite spectrometers, such as OMI and GOME-2.


Author(s):  
Maria Neufeld ◽  
Anna Bunova ◽  
Carina Ferreira-Borges ◽  
Evgeniy Bryun ◽  
Eugenia Fadeeva ◽  
...  

AbstractThe Alcohol Use Disorders Identification Test (AUDIT) is one of the most frequently used screening instrument for hazardous and harmful use of alcohol and potential alcohol dependence in primary health care (PHC) and other settings worldwide. It has been translated into many languages and adapted and modified for use in some countries, following formal adaptation procedures and validation studies. In the Russian Federation, the AUDIT has been used in different settings and by different health professionals, including addiction specialists (narcologists). In 2017, it was included as a screening instrument in the national guidelines of routine preventive health checks at the population-level (dispanserization). However, various Russian translations of the AUDIT are known to be in use in different settings and, so far, little is known about the empirical basis and validation of the instrument in Russia—a country, which is known for its distinct drinking patterns and their detrimental impact on health. The present contribution is the summary of two systematic reviews that were carried out to inform a planned national validation study of the AUDIT in Russia.Two systematic searches were carried out to 1) identify all validation efforts of the AUDIT in Russia and to document all reported problems encountered, and 2) identify all globally existing Russian translations of the AUDIT and document their differences and any reported issues in their application. The qualitative narrative synthesis of all studies that met the inclusion criteria of the first search highlighted the absence of any large-scale rigorous validation study of the AUDIT in primary health care in Russia, while a document analysis of all of the 122 Russian translations has revealed 61 unique versions, most of which contained inconsistencies and signaled obvious application challenges of the test.The results clearly signal the need for a validation study of the Russian AUDIT.


2021 ◽  
Author(s):  
Maria Neufeld ◽  
Anna Bunova ◽  
Carina Ferreira-Borges ◽  
Evgeniy Bryun ◽  
Eugenia Fadeeva ◽  
...  

Abstract The Alcohol Use Disorders Identification Test (AUDIT) is one of the most frequently used screening instrument for hazardous and harmful use of alcohol and potential alcohol dependence in primary health care (PHC) and other settings worldwide. It has been translated into many languages and adapted and modified for use in some countries, following formal adaptation procedures and validation studies. In the Russian Federation, the AUDIT has been used in different settings and by different health professionals, including addiction specialists (narcologists). In 2017, it was included as a screening instrument in the national guidelines of routine preventive health checks at the population-level (dispanserization). However, various Russian translations of the AUDIT are known to be in use in different settings and, so far, little is known about the empirical basis and validation of the instrument in Russia—a country, which is known for its distinct drinking patterns and their detrimental impact on health. The present contribution is the summary of two systematic reviews that were carried out to inform a planned national validation study of the AUDIT in Russia.Two systematic searches were carried out to 1) identify all validation efforts of the AUDIT in Russia and to document all reported problems encountered, and 2) identify all globally existing Russian translations of the AUDIT and document their differences and any reported issues in their application. The qualitative narrative synthesis of all studies that met the inclusion criteria of the first search highlighted the absence of any large-scale rigorous validation study of the AUDIT in primary health care in Russia, while a document analysis of all of the 122 Russian translations has revealed 61 unique versions, most of which contained inconsistencies and signaled obvious application challenges of the test.The results clearly signal the need for a validation study of the Russian AUDIT.


2017 ◽  
Vol 35 (3) ◽  
pp. 231-246
Author(s):  
Robert Epstein ◽  
Megan Ho ◽  
Seojin Hyun ◽  
Christopher Le ◽  
Ronald E. Robertson ◽  
...  

2020 ◽  
Author(s):  
Joshua J. Levy ◽  
Nasim Azizgolshani ◽  
Michael J. Andersen ◽  
Arief Suriawinata ◽  
Xiaoying Liu ◽  
...  

AbstractNon-alcoholic steatohepatitis (NASH) is a fatty liver disease characterized by accumulation of fat in hepatocytes with concurrent inflammation and is associated with morbidity, cirrhosis and liver failure. After extraction of a liver core biopsy, tissue sections are stained with hematoxylin and eosin (H&E) to grade NASH activity, and stained with trichrome to stage fibrosis. Methods to computationally transform one stain into another on digital whole slide images (WSI) can lessen the need for additional physical staining besides H&E, reducing personnel, equipment, and time costs. Generative adversarial networks (GAN) have shown promise for virtual staining of tissue. We conducted a large-scale validation study of the viability of GANs for H&E to trichrome conversion on WSI (n = 574). Pathologists were largely unable to distinguish real images from virtual/synthetic images given a set of twelve Turing Tests. We report high correlation between staging of real and virtual stains ($${\rho} = 0.86$$ ρ = 0.86 ; 95% CI: 0.84–0.88). Stages assigned to both virtual and real stains correlated similarly with a number of clinical biomarkers and progression to End Stage Liver Disease (Hazard Ratio HR = 2.06, 95% CI: 1.36–3.12, p < 0.001 for real stains; HR = 2.02, 95% CI: 1.40–2.92, p < 0.001 for virtual stains). Our results demonstrate that virtual trichrome technologies may offer a software solution that can be employed in the clinical setting as a diagnostic decision aid.


2005 ◽  
Author(s):  
T Phillips ◽  
A Henderson-Sellers ◽  
P Irannejad ◽  
K McGuffie ◽  
H Zhang

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