scholarly journals Skin Tightening With Hyperdilute CaHA: Dilution Practices and Practical Guidance for Clinical Practice

2021 ◽  
Author(s):  
Z Paul Lorenc ◽  
Jeanette M Black ◽  
Jessie S Cheung ◽  
Annie Chiu ◽  
Roberta Del Campo ◽  
...  
Keyword(s):  
Clinical Practice ◽  
The United States ◽  
Tissue Response ◽  
Injection Technique ◽  
Skin Tightening ◽  
Filler Injection ◽  
Medical Education Program ◽  
The Face ◽  
Practical Guidance ◽  
Lymphocytic Infiltrates

Abstract Background Over the past several years, hyperdilute calcium hydroxylapatite (CaHA) has emerged as an effective modality for improving skin quality and managing laxity in the face, arms, hands, neck, décolletage, upper arms, abdomen, buttocks, and upper legs, as well as treating cellulite and striae. While undiluted CaHA is used to provide volume, hyperdilute CaHA is distributed across a much larger surface area in a more superficial plane to stimulate neocollagenesis and elastin formation over time. The absence of lymphocytic infiltrates and predominance of type 1 collagen in the tissue response to CaHA make hyperdilute CaHA a valuable tool for nonsurgical skin tightening. Objectives Provide practical step-by-step guidance on patient selection, dilution practices, and optimal injection technique to facilitate incorporation of the technique into clinical practice. Methods Over the course of 3 regional meetings in the United States, 12 expert physician injectors participated in live webinars as part of a continuing medical education program. Results The practical guidance in this manuscript is based upon the most frequently requested information by audience members and the information considered critical for success by the authors. Conclusions The minimally invasive nature of filler injection results in little down time, making this treatment particularly appealing. The recommendations presented are consistent with previously published consensus guidelines on hyperdilute CaHA but are intended to serve as “how-to” guidance from experience of expert injectors who have successfully treated the face and body.

scholarly journals Combined use of fractional co2 laser and collagenase diadynamophoresis in correction of contour plastic surgery complications

2020 ◽  
Vol 17 (5) ◽  
pp. 246-251
Author(s):  
Marina Yu. Gerasimenko ◽  
Irina P. Alekseenko
Keyword(s):  
Plastic Surgery ◽  
Co2 Laser ◽  
Calcium Hydroxyapatite ◽  
Injection Technique ◽  
Skin Tightening ◽  
Fractional Co2 Laser ◽  
Filler Injection ◽  
Combined Use ◽  
Superficial Skin ◽  
The Face

Background. One of the most frequent complications of aesthetic correction methods is the problem of contouring, visualization, or local tightening of the skin at the sites of administration of the agent based on calcium hydroxyapatite, which occurs in violation of the injection technique. Aim: to study the efficiency of the combined method including a course of diadynamophoresis of collagenase 1000 KE (collagenase units) and a fractional CO2 laser procedure in correction of a surface-injected preparation in late terms. Methods. Clinical and instrumental examination of 24 women (average age 38.2 3.5 years) was conducted. All patients complained of complications after the contour plastic surgery procedure using a preparation based on calcium hydroxyapatite, in the form of contouring of the preparation and superficial skin tightening on the face at the filler injection site. Results. When comparing the control, main and reference groups, it was revealed that the combined use of collalysin diadynamophoresis and fractional CO2 laser at low parameters improves significantly the quality of life in terms of the adapted dermatological index. Clinical improvement was registered in all groups, but it was most significant in the main one, which correlated with the data of ultrasound examination with a 33 MHz sensor. In the main group, faster biodegradation was noted, and the volume of the surface-injected filler decreased 2.5 times after 1 month and 6 times after 2 months. Conclusion. The combined use of collalysin diadynamophoresis and a fractional CO2 laser is an effective complex for the correction of complications after contour plastic surgery of fillers based on calcium hydroxyapatite.

scholarly journals Combined use of fractional co2 laser and collagenase diadynamophoresis in correction of contour plastic surgery complications

2020 ◽  
Vol 17 (5) ◽  
pp. 246-251
Author(s):  
Marina Yu. Gerasimenko ◽  
Irina P. Alekseenko
Keyword(s):  
Plastic Surgery ◽  
Co2 Laser ◽  
Calcium Hydroxyapatite ◽  
Injection Technique ◽  
Skin Tightening ◽  
Fractional Co2 Laser ◽  
Filler Injection ◽  
Combined Use ◽  
Superficial Skin ◽  
The Face

Background. One of the most frequent complications of aesthetic correction methods is the problem of contouring, visualization, or local tightening of the skin at the sites of administration of the agent based on calcium hydroxyapatite, which occurs in violation of the injection technique. Aim: to study the efficiency of the combined method including a course of diadynamophoresis of collagenase 1000 KE (collagenase units) and a fractional CO2 laser procedure in correction of a surface-injected preparation in late terms. Methods. Clinical and instrumental examination of 24 women (average age 38.2 3.5 years) was conducted. All patients complained of complications after the contour plastic surgery procedure using a preparation based on calcium hydroxyapatite, in the form of contouring of the preparation and superficial skin tightening on the face at the filler injection site. Results. When comparing the control, main and reference groups, it was revealed that the combined use of collalysin diadynamophoresis and fractional CO2 laser at low parameters improves significantly the quality of life in terms of the adapted dermatological index. Clinical improvement was registered in all groups, but it was most significant in the main one, which correlated with the data of ultrasound examination with a 33 MHz sensor. In the main group, faster biodegradation was noted, and the volume of the surface-injected filler decreased 2.5 times after 1 month and 6 times after 2 months. Conclusion. The combined use of collalysin diadynamophoresis and a fractional CO2 laser is an effective complex for the correction of complications after contour plastic surgery of fillers based on calcium hydroxyapatite.

Prevention and Management of Filler Induced Iatrogenic Stroke of the Eye

2021 ◽  
pp. 120347542199934
Author(s):  
John P. Arlette ◽  
Michael Ashenhurst ◽  
Vivian Hill ◽  
Kailun Jiang
Keyword(s):  
Hyaluronic Acid ◽  
Patient Characteristics ◽  
Injection Technique ◽  
Sudden Loss ◽  
Filler Injection ◽  
The Past ◽  
Facial Esthetics ◽  
The Face ◽  
Ophthalmologic Examination ◽  
Retinal Artery

In the past few decades, minimally-invasive esthetic treatments and the use of injectable Hyaluronic Acid Gels and other filling agents to treat facial esthetics have increased dramatically. Although extremely rare, a filler can cause ocular and orbital ischemia by retrograde flow from the ophthalmic artery when injected in any of the anastomosis of the face. Once filler reaches the central retinal artery, blindness is inevitable, and no treatment is effective. While the risk of blindness happening with any filler injection is rare, the life-altering irreversible consequence of a procedure that was anticipated to be simple and beautifying is a reality that each injector must be prepared for with every injection. The parameters associated with an iatrogenic stroke of the eye are the site of injection, the injection technique, patient characteristics, and the material injected. Understanding the interplay of each of these variables might help us reduce the possibility of blindness during the injection of a soft-tissue cosmetic filler. Here, we explore the causes of Hyaluronic Acid Gels Filler embolic phenomena, review the natural course of the process, and discuss appropriate immediate interventions. We also (1) propose an education plan for injectors and describe how to carry out a focused ophthalmologic examination and procedural activities for a referral to an ophthalmologist, (2) outline steps to prevent emboli during filler injection, and (3) how to manage and support a patient with a sudden loss of vision during or immediately after a Hyaluronic Acid Gels filler treatment.

Overview of Current Approaches to Aural Rehabilitation for Adults With Cochlear Implants

2020 ◽  
Vol 5 (5) ◽  
pp. 1175-1187
Author(s):  
Rachel Glade ◽  
Erin Taylor ◽  
Deborah S. Culbertson ◽  
Christin Ray
Keyword(s):  
Health Care ◽  
Clinical Practice ◽  
Cochlear Implants ◽  
Practice Patterns ◽  
The United States ◽  
Care Providers ◽  
Aural Rehabilitation ◽  
Starting Point ◽  
Clinical Models ◽  
Hearing Health

Purpose This clinical focus article provides an overview of clinical models currently being used for the provision of comprehensive aural rehabilitation (AR) for adults with cochlear implants (CIs) in the Unites States. Method Clinical AR models utilized by hearing health care providers from nine clinics across the United States were discussed with regard to interprofessional AR practice patterns in the adult CI population. The clinical models were presented in the context of existing knowledge and gaps in the literature. Future directions were proposed for optimizing the provision of AR for the adult CI patient population. Findings/Conclusions There is a general agreement that AR is an integral part of hearing health care for adults with CIs. While the provision of AR is feasible in different clinical practice settings, service delivery models are variable across hearing health care professionals and settings. AR may include interprofessional collaboration among surgeons, audiologists, and speech-language pathologists with varying roles based on the characteristics of a particular setting. Despite various existing barriers, the clinical practice patterns identified here provide a starting point toward a more standard approach to comprehensive AR for adults with CIs.

Verán ustedes las chozas más humildes. El discurso de pobreza en la diplomacia pública cardenista dirigida a Estados Unidos

2019 ◽  
Vol 35 (2) ◽  
pp. 255-281
Author(s):  
Sylvia Dümmer Scheel
Keyword(s):  
United States ◽  
New Deal ◽  
Public Diplomacy ◽  
The United States ◽  
The Public ◽  
The Poor ◽  
The Face ◽  
The Government ◽  
Lazaro Cardenas ◽  
The New Deal

El artículo analiza la diplomacia pública del gobierno de Lázaro Cárdenas centrándose en su opción por publicitar la pobreza nacional en el extranjero, especialmente en Estados Unidos. Se plantea que se trató de una estrategia inédita, que accedió a poner en riesgo el “prestigio nacional” con el fin de justificar ante la opinión pública estadounidense la necesidad de implementar las reformas contenidas en el Plan Sexenal. Aprovechando la inusual empatía hacia los pobres en tiempos del New Deal, se construyó una imagen específica de pobreza que fuera higiénica y redimible. Ésta, sin embargo, no generó consenso entre los mexicanos. This article analyzes the public diplomacy of the government of Lázaro Cárdenas, focusing on the administration’s decision to publicize the nation’s poverty internationally, especially in the United States. This study suggests that this was an unprecedented strategy, putting “national prestige” at risk in order to explain the importance of implementing the reforms contained in the Six Year Plan, in the face of public opinion in the United States. Taking advantage of the increased empathy felt towards the poor during the New Deal, a specific image of hygienic and redeemable poverty was constructed. However, this strategy did not generate agreement among Mexicans.

Terrified

2014 ◽  
Author(s):  
Christopher A. Bail
Keyword(s):  
Public Discourse ◽  
The United States ◽  
September 11 ◽  
Theoretical Argument ◽  
Muslim Americans ◽  
Media Messages ◽  
American Media ◽  
The Face ◽  
September 11 Attacks ◽  
The Public Sphere

In July 2010, Terry Jones, the pastor of a small fundamentalist church in Florida, announced plans to burn two hundred Qur'ans on the anniversary of the September 11 attacks. Though he ended up canceling the stunt in the face of widespread public backlash, his threat sparked violent protests across the Muslim world that left at least twenty people dead. This book demonstrates how the beliefs of fanatics like Jones are inspired by a rapidly expanding network of anti-Muslim organizations that exert profound influence on American understanding of Islam. The book traces how the anti-Muslim narrative of the political fringe has captivated large segments of the American media, government, and general public, validating the views of extremists who argue that the United States is at war with Islam and marginalizing mainstream Muslim-Americans who are uniquely positioned to discredit such claims. Drawing on cultural sociology, social network theory, and social psychology, the book shows how anti-Muslim organizations gained visibility in the public sphere, commandeered a sense of legitimacy, and redefined the contours of contemporary debate, shifting it ever outward toward the fringe. The book illustrates the author's pioneering theoretical argument through a big-data analysis of more than one hundred organizations struggling to shape public discourse about Islam, tracing their impact on hundreds of thousands of newspaper articles, television transcripts, legislative debates, and social media messages produced since the September 11 attacks. The book also features in-depth interviews with the leaders of these organizations, providing a rare look at how anti-Muslim organizations entered the American mainstream.

New Drugs of 2012: A Concise Overview of the NMEs and Trends for Innovative Brand Market in the United States

2013 ◽  
Vol 6 (2) ◽  
pp. 2009-2013
Author(s):  
D Samba Reddy
Keyword(s):  
Drug Approval ◽  
The United States ◽  
New Drugs ◽  
New Combination ◽  
Drug Status ◽  
Combination Drug ◽  
Human Cord Blood ◽  
Life Saving ◽  
Genomics And Proteomics ◽  
The Face

Thirty-nine (39) new drugs have been approved by the U.S. FDA in 2012, a record highest number of approvals since 1996. The record is a sign that pharma companies are poised to tap recent advances from genomics and proteomics. This list includes novel new drugs, known as new molecular entities (NMEs), biologics and new products. Many life-saving drugs are approved for marketing. The list includes a total of 10 drugs for cancer treatment, and nearly a quarter of those approved in 2012 had orphan drug status.  Among the breakthrough drugs approved in 2012 were ivacaftor (cystic fibrosis), vasmodegib (skin cancer), HPC-C (human cord blood product), ruxolitinib (myelofibrosis) and a new combination drug to treat HIV. In addition,  several unique products were approved for the treatment of macular degeneration, chronic weight management, overactive bladder, actinic keratosis, erectile dysfunction, glaucoma, respiratory distress syndrome, and COPD. The approval of 39 drugs in 2012 underscores a robust success rate and confirms that innovation is once again beginning to pay off. In the existing climate of reduced revenues in the face of generic competitions, the future and survival of big companies rests heavily on their unique niche products. It is apparent that big Pharma and a growing number of emerging Biotechs alike have focused their attention on developing new NMEs for rare diseases. In 2012, the length of the FDA’s review is shorter than agencies in other countries. Innovative models adopted for R&D strategies, communications, and new regulatory changes appear to shorten development timelines. Despite record drug approvals, there is bleak scope for blockbusters because most of these drugs have a limited market. The pipeline for blockbusters appears very low. However, there is unmet medical need for new drugs in autism, Alzheimer’s disease and epilepsy. Overall, the new drug approval list unveils unique and reemerging trends indicating that the pharma companies are poised for big growth from new brands approved for marketing for narrow-spectrum indications.    

The New Economic Populism and the Future of Inequality in the United States

2017 ◽  
Author(s):  
William W. Franko ◽  
Christopher Witko
Keyword(s):  
United States ◽  
Federal Government ◽  
Labor Unions ◽  
Republican Party ◽  
The United States ◽  
The Public ◽  
Empirical Results ◽  
Income Disparities ◽  
The Face ◽  
Over Time

The authors conclude the book by recapping their arguments and empirical results, and discussing the possibilities for the “new economic populism” to promote egalitarian economic outcomes in the face of continuing gridlock and the dominance of Washington, DC’s policymaking institutions by business and the wealthy, and a conservative Republican Party. Many states are actually addressing inequality now, and these policies are working. Admittedly, many states also continue to embrace the policies that have contributed to growing inequality, such as tax cuts for the wealthy or attempting to weaken labor unions. But as the public grows more concerned about inequality, the authors argue, policies that help to address these income disparities will become more popular, and policies that exacerbate inequality will become less so. Over time, if history is a guide, more egalitarian policies will spread across the states, and ultimately to the federal government.

Ban Ki-moon, 2007–2016

2018 ◽  
Author(s):  
Richard Gowan
Keyword(s):  
United States ◽  
Decision Making ◽  
Security Council ◽  
Large Scale ◽  
Central African Republic ◽  
The United States ◽  
Cautious Approach ◽  
Peacekeeping Operations ◽  
Council Decision ◽  
The Face

During Ban Ki-moon’s tenure, the Security Council was shaken by P5 divisions over Kosovo, Georgia, Libya, Syria, and Ukraine. Yet it also continued to mandate and sustain large-scale peacekeeping operations in Africa, placing major burdens on the UN Secretariat. The chapter will argue that Ban initially took a cautious approach to controversies with the Council, and earned a reputation for excessive passivity in the face of crisis and deference to the United States. The second half of the chapter suggests that Ban shifted to a more activist pressure as his tenure went on, pressing the Council to act in cases including Côte d’Ivoire, Libya, and Syria. The chapter will argue that Ban had only a marginal impact on Council decision-making, even though he made a creditable effort to speak truth to power over cases such as the Central African Republic (CAR), challenging Council members to live up to their responsibilities.

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