scholarly journals Incidence and Correlates of Sexually Transmitted Infections Among Black Men Who Have Sex With Men Participating in the HIV Prevention Trials Network 073 Preexposure Prophylaxis Study

2019 ◽  
Vol 69 (9) ◽  
pp. 1597-1604 ◽  
Author(s):  
Lisa B Hightow-Weidman ◽  
Manya Magnus ◽  
Geetha Beauchamp ◽  
Christopher B Hurt ◽  
Steve Shoptaw ◽  
...  
Keyword(s):  
Hiv Prevention ◽  
Sexually Transmitted Infections ◽  
Black Men ◽  
Sexual Behaviors ◽  
Nucleic Acid Amplification ◽  
Sexually Transmitted ◽  
Preexposure Prophylaxis ◽  
Centered Care ◽  
Prevention Trials ◽  
Sex With Men

Abstract Background The HIV Prevention Trials Network (HPTN) Study 073 (HPTN 073) assessed the feasibility, acceptability, and safety of preexposure prophylaxis (PrEP) for black men who have sex with men (BMSM). The purpose of this analysis was to characterize the relationship between PrEP uptake and use and incident sexually transmitted infections (STIs) among participants enrolled in HPTN 073. Methods A total of 226 human immunodeficiency virus (HIV)–uninfected BMSM were enrolled in 3 US cities; all participants received client-centered care coordination (C4) and were offered daily oral PrEP. Participants were followed for 12 months with STI testing (rectal and urine nucleic acid amplification test for gonorrhea and chlamydia, rapid plasma reagin for syphilis) conducted at baseline, week 26, and week 52. Logistic regression was used to examine associations between STI incidence and PrEP uptake. Generalized estimating equations were used to evaluate associations between age, PrEP acceptance, sexual behaviors, and incident STIs. Results Baseline STI prevalence was 14.2%. Men aged <25 years were more likely to have a baseline STI (25.3% vs 6.7%; odds ratio [OR], 4.39; 95% confidence interval [CI:, 1.91, 10.11). Sixty participants (26.5%) acquired ≥1 STI during follow-up; the incidence rate was 34.2 cases per 100 person-years (95% CI, 27.4, 42.9). In adjusted analyses, baseline STI diagnosis (OR, 4.23; 95% CI, 1.82, 9.87; P < .001) and additional C4 time (OR, 1.03; 95% CI, 1.00, 1.06; P = .027) were associated with having an incident STI. STI incidence was not associated with PrEP acceptance or adherence. Conclusions While we found higher rates of STIs in younger BMSM, overall rates of STI were lower than in prior PrEP trials, with no increase over time. BMSM with STIs at PrEP initiation may require additional interventions that target STI acquisition risk. Clinical Trials Registration NCT01808352.

Multifactorial Correlates of Incident Bacterial Sexually Transmitted Infections Among Black Men Who have Sex with Men Recruited in 6 US Cities (HPTN 061)

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Lao-Tzu Allan-Blitz ◽  
Timothy W. Menza ◽  
Vanessa Cummings ◽  
Charlotte A. Gaydos ◽  
Leo Wilton ◽  
...  
Keyword(s):  
Sexually Transmitted Infections ◽  
Black Men ◽  
Sexually Transmitted ◽  
Sex With Men ◽  
Us Cities

Risky sexual behavior and sexually transmitted infections among men who have sex with men and purchase sex attending an Israeli sexually transmitted infection clinic

2019 ◽  
Vol 31 (3) ◽  
pp. 236-243 ◽  
Author(s):  
Rivka S Rich ◽  
Alex Leventhal ◽  
Rivka Sheffer ◽  
Zohar Mor
Keyword(s):  
High Risk ◽  
Sexually Transmitted Infections ◽  
Sexual Behaviors ◽  
Risky Sexual Behavior ◽  
Laboratory Data ◽  
Cross Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Sex With Men

Men who have sex with men (MSM) and purchase sex (MPS) are a sub-group potentially at high risk for acquiring and transmitting sexually transmitted infections (STIs). This is a hard-to-reach population resulting in a scarcity of studies covering the issue. This cross-sectional study aimed to assess the association between purchasing sex and high-risk behaviors related to HIV/STI transmission and appraise the STI prevalence among MSM. All MSM who attended the STI clinic in Tel Aviv between 2003 and 2010 were included. Demographics, behavioral, clinical, and laboratory data were compared between MPS and non-MPS to identify high-risk sexual behaviors and STI prevalence associated with purchasing sex. Of the first visits of 2694 MSM who attended the STI clinic during the study period, 151 (5.6%) paid for sex. MPS were more commonly older and married than non-MPS. MPS were more likely to engage in behaviors associated with high risk for HIV/STI transmission, including infrequent condom use during anal sex, substance use during sex, and selling sex themselves. MPS had a higher STI prevalence than non-MPS, although this was not statistically significant ( p = 0.05). These findings highlight the need to establish culturally tailored interventions for MPS addressing the potential risks associated with purchasing sex.

scholarly journals Sexually transmitted infections and sexual behaviors of men who have sex with men in an American Deep South PrEP clinic

2020 ◽  
Vol 31 (2) ◽  
pp. 127-135 ◽  
Author(s):  
Ronnie M Gravett ◽  
Andrew O Westfall ◽  
Edgar T Overton ◽  
Kachina Kudroff ◽  
Christina A Muzny ◽  
...  
Keyword(s):  
High Risk ◽  
Sexually Transmitted Infections ◽  
Incidence Rate ◽  
Sexual Behaviors ◽  
The United States ◽  
Sexual Partners ◽  
Deep South ◽  
Multiple Sexual Partners ◽  
Sexually Transmitted ◽  
Sex With Men

HIV pre-exposure prophylaxis (PrEP) effectively prevents HIV acquisition among men who have sex with men (MSM), but PrEP uptake has been associated with sexually transmitted infections (STIs). The effect of PrEP on STIs in MSM in the Deep South of the United States is unknown. We performed a retrospective analysis of adult MSM at an American Deep South PrEP clinic to calculate the prevalence and incidence rate of bacterial STIs (chlamydia, gonorrhea, and syphilis) and identify associated risk factors by linking incident STI to patient-reported outcomes; 139 MSM accessed the clinic between 2014 and 2018 with baseline bacterial STI prevalence of 11%. Twenty-six of 81 eligible MSM on PrEP had incident STIs with an incidence rate of 33.1 cases per 100 person-years. Significantly higher proportions of high PrEP adherence, multiple sexual partners, and inconsistent condom use were seen in those with incident STI, and we identified MSM with both high PrEP adherence and multiple sexual partners as being at especially high risk for bacterial STIs (hazard ratio: 7.57, 95% confidence interval: 1.75–32.74). Bacterial STIs are common after initiating PrEP in this clinic, and MSM reporting high PrEP adherence and multiple sexual partners have a significant risk for incident STI. High-risk sexual behaviors persisted after starting PrEP, highlighting the importance of ongoing, intensive sexual health screening and interventions.

scholarly journals The Duality of Oral Sex for Men Who Have Sex with Men: An Examination Into the Increase of Sexually Transmitted Infections Amid the Age of HIV Prevention

2017 ◽  
Vol 31 (6) ◽  
pp. 261-267 ◽  
Author(s):  
Tiffany R. Glynn ◽  
Don Operario ◽  
Madeline Montgomery ◽  
Alexi Almonte ◽  
Philip A. Chan
Keyword(s):  
Hiv Prevention ◽  
Sexually Transmitted Infections ◽  
Oral Sex ◽  
Sexually Transmitted ◽  
Sex With Men

scholarly journals Short Communication: Viral Genetic Linkage Analysis Among Black Men Who Have Sex With Men (HIV Prevention Trials Network 061)

2019 ◽  
Vol 35 (5) ◽  
pp. 434-436
Author(s):  
Julia Kobe ◽  
Octavious Talbot ◽  
Iris Chen ◽  
Susan H. Eshleman ◽  
Vanessa Cummings ◽  
...  
Keyword(s):  
Hiv Prevention ◽  
Linkage Analysis ◽  
Black Men ◽  
Genetic Linkage ◽  
Short Communication ◽  
Genetic Linkage Analysis ◽  
Prevention Trials ◽  
Sex With Men

scholarly journals Social and Behavioral Correlates of Sexually Transmitted Infections among Men who Have Sex with Men who Use Alcohol in the San Francisco Bay Area

2021 ◽  
Vol 15 (3) ◽  
pp. 155798832110268
Author(s):  
Jennifer P. Jain ◽  
Akua O. Gyamerah ◽  
Glenda N. Baguso ◽  
Carol Dawson-Rose ◽  
Janet Ikeda ◽  
...  
Keyword(s):  
Sexually Transmitted Infections ◽  
San Francisco ◽  
Sexual Behaviors ◽  
Cross Sectional Study ◽  
Hiv Status ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Logistic Regression Models ◽  
The Past ◽  
Sex With Men

The risk of acquiring sexually transmitted infections (STIs) among men who have sex with men (MSM) is driven by various socio-behavioral factors. From 2015-2017, 247 MSM ≥ 18 years-old who reported alcohol use in the past year, were recruited into a cross-sectional study in San Francisco. Participants completed a survey assessing socio-demographics, substance use and treatment, sexual behaviors, HIV status and self-reported STI diagnosis in the past 6 months. Multivariable logistic regression models stratified by HIV status were used to identify the correlates of STIs. Of 247 MSM, the prevalence of bacterial STIs were: gonorrhea (12.9%), chlamydia (9.3%) and syphilis (6.0%). Among 177 MSM living without HIV, factors significantly associated with recent STI diagnosis were: current pre-exposure prophylaxis (PrEP) use (aOR = 3.53, 95% CI: 1.42–8.75, p ≤ .01), popper use during sex in the past 6 months (aOR = 3.16, 95% CI = 1.34–7.47, p ≤ .01) and a history of alcohol treatment (aOR = 0.17, 95% CI = 0.04–0.68, p = .01). Also, in a sensitivity analysis (removing PrEP), any receptive condomless anal sex was independently associated with recent STI diagnosis (aOR = 2.86, 95% CI = 1.15–7.08, p = .02). Among 70 MSM living with HIV, factors significantly associated with recent STI diagnosis were: White race/ethnicity (adjusted odds ratio [aOR] = 7.36, 95% confidence interval [CI] = 1.48–36.62, p = .01), younger age (aOR = 0.90, 95% CI: 0.84–0.97, p < .01) and a higher number of male sexual partners in the past 6 months (aOR = 1.03, 95% CI = 1.00–1.06, p = .02). Sexual health interventions that address the unique needs of MSM living with and without HIV who use alcohol in San Francisco are needed to reduce STI acquisition and transmission.

scholarly journals Screening for genital and anorectal sexually transmitted infections in HIV prevention trials in Africa

2008 ◽  
Vol 84 (5) ◽  
pp. 364-370 ◽  
Author(s):  
M L Grijsen ◽  
S M Graham ◽  
M Mwangome ◽  
P Githua ◽  
S Mutimba ◽  
...  
Keyword(s):  
Hiv Prevention ◽  
Sexually Transmitted Infections ◽  
Sexually Transmitted ◽  
Prevention Trials

scholarly journals Development of a Black Caucus within the HIV Prevention Trials Network (HPTN): Representing the Perspectives of Black Men Who Have Sex with Men (MSM)

2020 ◽  
Vol 17 (3) ◽  
pp. 871 ◽  
Author(s):  
Christopher Watson ◽  
Leo Wilton ◽  
Jonathan Lucas ◽  
Lawrence Bryant ◽  
Gregory Victorianne ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Hiv Prevention ◽  
Black Men ◽  
The United States ◽  
Black Msm ◽  
Black Caucus ◽  
Prevention Trials ◽  
Hiv Clinical Trials ◽  
Sex With Men

Black men who have sex with men (MSM) have disproportionate HIV disease burden in the United States. Black MSM have been underrepresented in biomedical research, including HIV clinical trials, due to a myriad of socio-structural, socio-cultural, and psychosocial factors. The HIV Prevention Trials Network (HPTN) 061, a feasibility study of a multi-component HIV prevention intervention for Black MSM in six US cities, incorporated the development and implementation of a Black Caucus as a culturally grounded model for the integration of Black MSM in clinical trials and research in HPTN. Based on a qualitative methodological approach, we describe the formation and implementation of the Black Caucus from the perspective of Black MSM key community stakeholders. Three major themes emerged from the qualitative narratives: (1) the role of the Black Caucus in shaping the HPTN, (2) how the Black Caucus addresses the needs of Black MSM communities pertaining to the influence of race and sexual identity, and (3) socio-cultural needs of Black MSM. These findings have implications for the provision of culturally congruent expertise, community engagement, cultural mistrust, recruitment and retention of Black MSM in HIV clinical trials, culturally-relevant study design and implementation, and the role of developing Black MSM prevention researchers.

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