scholarly journals The role of psychological factors in fatigue among end-stage kidney disease patients: a critical review

2016 ◽  
pp. sfw113 ◽  
Author(s):  
Federica Picariello ◽  
Rona Moss-Morris ◽  
Iain C. Macdougall ◽  
Joseph Chilcot
Keyword(s):  
Kidney Disease ◽  
Critical Review ◽  
Psychological Factors ◽  
End Stage Kidney Disease ◽  
End Stage

scholarly journals Advocacy for renal replacement therapy: the role of renal registries

2020 ◽  
Vol 13 (5) ◽  
pp. 742-744
Author(s):  
Cecile Couchoud ◽  
Mohamed Benghanem Gharbi
Keyword(s):  
Renal Replacement Therapy ◽  
Kidney Disease ◽  
Replacement Therapy ◽  
South African ◽  
Limited Resource ◽  
Service Planning ◽  
End Stage Kidney Disease ◽  
End Stage ◽  
Resource Environment

Abstract The paper by Jardine et al. reporting results from the South African Renal Registry describes a 2-fold success. First, even in a limited-resource environment, survival of patients on renal replacement therapy (RRT) is favourable. Secondly, this information is available because a few years ago, South African nephrologists started a renal registry. These successes cannot conceal, however, that numerous patients are not offered RRT. Robust health information systems make it possible to define chronic kidney disease and end-stage kidney disease (ESKD) burdens, guide resource allocation, inform service planning and enable policy. Registries can highlight inequitable RRT access and help support advocacy in favour of additional resources for ESKD care.

High risk of development of renal cell tumor in end-stage kidney disease: the role of microenvironment

Tumor Biology ◽  
2016 ◽  
Vol 37 (7) ◽  
pp. 9511-9519 ◽  
Author(s):  
Anetta Nagy ◽  
Eva Walter ◽  
Dmitry Zubakov ◽  
Gyula Kovacs
Keyword(s):  
High Risk ◽  
Kidney Disease ◽  
Renal Cell ◽  
Cell Tumor ◽  
End Stage Kidney Disease ◽  
End Stage

Role of Haptoglobin Phenotype in End-Stage Kidney Disease

2004 ◽  
Vol 97 (2) ◽  
pp. e71-e76 ◽  
Author(s):  
Zvi Burbea ◽  
Farid Nakhoul ◽  
Shai Rosenberg ◽  
Roaa Zoabi ◽  
Karl Skorecki ◽  
...  
Keyword(s):  
Kidney Disease ◽  
End Stage Kidney Disease ◽  
Haptoglobin Phenotype ◽  
End Stage

scholarly journals Non-Coding RNAs as Biomarkers and Therapeutic Targets for Diabetic Kidney Disease

2021 ◽  
Vol 11 ◽  
Author(s):  
Yue-Yu Gu ◽  
Fu-Hua Lu ◽  
Xiao-Ru Huang ◽  
Lei Zhang ◽  
Wei Mao ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Diabetic Kidney Disease ◽  
Therapeutic Targets ◽  
Diabetic Complication ◽  
End Stage Kidney Disease ◽  
Diabetic Kidney ◽  
Non Coding Rna ◽  
Non Coding Rnas ◽  
End Stage

Diabetic kidney disease (DKD) is the most common diabetic complication and is a leading cause of end-stage kidney disease. Increasing evidence shows that DKD is regulated not only by many classical signaling pathways but also by epigenetic mechanisms involving chromatin histone modifications, DNA methylation, and non-coding RNA (ncRNAs). In this review, we focus on our current understanding of the role and mechanisms of ncRNAs, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in the pathogenesis of DKD. Of them, the regulatory role of TGF-β/Smad3-dependent miRNAs and lncRNAs in DKD is highlighted. Importantly, miRNAs and lncRNAs as biomarkers and therapeutic targets for DKD are also described, and the perspective of ncRNAs as a novel therapeutic approach for combating diabetic nephropathy is also discussed.

scholarly journals Mitophagy in Diabetic Kidney Disease

2021 ◽  
Vol 9 ◽  
Author(s):  
Xiaofeng Zhang ◽  
Jing Feng ◽  
Xia Li ◽  
Dan Wu ◽  
Qian Wang ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Diabetic Kidney Disease ◽  
Therapeutic Approaches ◽  
End Stage Kidney Disease ◽  
Common Cause ◽  
Diabetic Kidney ◽  
Increased Risk ◽  
Underlying Mechanisms ◽  
End Stage

Diabetic kidney disease (DKD) is the most common cause of end-stage kidney disease worldwide and is the main microvascular complication of diabetes. The increasing prevalence of diabetes has increased the need for effective treatment of DKD and identification of new therapeutic targets for better clinical management. Mitophagy is a highly conserved process that selectively removes damaged or unnecessary mitochondria via the autophagic machinery. Given the important role of mitophagy in the increased risk of DKD, especially with the recent surge in COVID-19-associated diabetic complications, in this review, we provide compelling evidence for maintaining homeostasis in the glomeruli and tubules and its underlying mechanisms, and offer new insights into potential therapeutic approaches for treatment of DKD.

Sign in / Sign up

Export Citation Format

Share Document