Microsampling for Blood-Lead Analysis

1974 ◽  
Vol 20 (2) ◽  
pp. 217-221 ◽  
Author(s):  
M P Bratzel ◽  
A Jane Reed
Keyword(s):  
Quality Control ◽  
System Approach ◽  
Blood Lead ◽  
Lead Content ◽  
Blood Collection ◽  
Total System ◽  
Micro Scale ◽  
Subsequent Determination ◽  
And Storage

Abstract We detail the technique, procedure, and equipment required to properly obtain a micro-scale capillary (fingerstick) blood specimen for subsequent determination of its lead content. We divide the microsampling procedure into preparation of sampling equipment and subject, the fingerstick, micro blood collection devices, and transport and storage. The concept of a total-system approach to quality control for sampling and analysis is presented. For realistic quality control, the sampling component and the analysis component are inseparable. We describe types and sources of errors encountered. Most of the variability in the total system is associated with sampling.

Determination of Trichlorfon in Technical and Powder Formulations

1988 ◽  
Vol 71 (2) ◽  
pp. 317-320
Author(s):  
Stephen C Slahck
Keyword(s):  
Quality Control ◽  
Liquid Chromatography ◽  
Storage Stability ◽  
Direct Determination ◽  
Ion Pairing ◽  
Uv Detection ◽  
Powder Formulation ◽  
Technical Material ◽  
And Storage

Abstract A facile procedure is described for the determination of trichlorfon in technical material and an 80% powder formulation by using liquid chromatography with ion-pairing and UV detection. Liquid chromatography allows the direct determination of trichlorfon and detection of any dichlorvos present. This method is applicable to quality control and storage stability analyses and eliminates any need for derivatization to counter the thermal lability of trichlorfon. The average standard deviations for the technical and 80% formulation determinations were 0.51 and 0.37%, respectively.

scholarly journals DEVELOPMENT OF ELISAS FOR THE QUALITY CONTROL OF A RECOMBINANT PSEUDOMONAS VACCINE

2019 ◽  
Vol 1 (1) ◽  
pp. 95-100
Author(s):  
A. V. Soldatenkova ◽  
E. M. Zimina ◽  
A. M. Kudryashova ◽  
N. F. Gavrilova ◽  
I. V. Yakovleva ◽  
...  
Keyword(s):  
Quality Control ◽  
Recombinant Proteins ◽  
Recombinant Vaccine ◽  
Accuracy And Precision ◽  
Residual Amount ◽  
Calibration Dependence ◽  
And Storage ◽  
Acceptable Reliability

Aim. Development and optimization of enzyme immunoassays for quality control of pseudomonas recombinant vaccine. Materials and methods. Recombinant proteins in intermediate products and for completeness of adsorption control were detected in sandwich immunoassay using specific polyclonal and monoclonal antibodies. Detection of the antigen in the vaccine was carried out on the residual amount of antibodies specific to toxoid or OprF that did not bind to the vaccine preparation during the preincubation. Results. ELISAs have been developed and optimized for the quantitative determination of the components (toxoid and membrane protein OprF) of the Pseudomonas recombinant vaccine during the production process. It has been established that: the methods are specific for the determination of toxoid and OprF, the quantitative limit determination has acceptable reliability, the possibility of choosing interpolation of the calibration dependence within the analytical area is shown, the accuracy and precision meets the acceptance criteria, the technique is stable under the conditions of the analysis. Conclusion. Methods can be used to control the quality of the drug during its developing and storage.

scholarly journals Innovational system of quality control of seeding material in corn seed growing

2020 ◽  
Vol 4 (2) ◽  
pp. 243-250
Author(s):  
M. Ya. Kyrpa ◽  
O. F. Stasiv ◽  
T. M. Lukyanenko
Keyword(s):  
Quality Control ◽  
Individual Plant ◽  
Corn Hybrids ◽  
Corn Seed ◽  
Seeding Material ◽  
Processing And Storage ◽  
And Storage ◽  
Seed Growing ◽  
Quality Indexes

Results of quality investigations of corn hybrids seeds that are formed at the growing phases, postharvest processing and storage are expounded. Quality control system which is based on the acting (standardized) and additional indexes and also methods of their definition is worked out. Seeds viability on the cold germination method, energy and growth force, uniformity and damage are additional indexes, they have high correlation level with sowing qualities and plenteous hybrids properties. Cold germination method includes variable temperatures 8 – 10 and 18 – 20 degrees Celsius that reproduces conditions of “sowing – seedling” corn period in the field. The uniformity is determined by the method of separating seeding material and determination of some fractions content on seeds size 9, 8, 7, 6 mm in it. The damage is defined by looking-over seedlings through a magnifying glass and their separating into 3 groups: seeds which are not damaged, with macro- and micro- damage of germ and endosperm, also seeds with damage in the kind of plucked veil are separately distinguished. The largest level of additional indexes correlation determined by new methods is within r = 0,583 – 0.781 and refers to the field seeds germination, individual plant productivity of corn hybrids. On the base of acting and additional indexes conditioned seeds are offered to be evaluated in accordance with 3 indexes of sowing suitability. If seeds of the first and the second (high and medium) indexes are used marketable seeds of corn hybrids productivity can be increased on 15–18 %. The highest index seeds viability on the method of cold germination must be 85–100 %, quantity of strong plantlets – no less 81 %, uniformity – 91 % and more, content of seeds with macro damage – till 5 % and micro damage – till 29 %. The system of quality control is recommended to be used in the process of seeds preparation and on the phase of their certification. Key words: corn, hybrids, seeds, system of quality, indexes and methods.

Determination of the Prospective Processed Cacao Product and Calculation of the Added Value in Agro-Tourism Based on Cacao Agroindustry in Pidie Jaya Regency

2018 ◽  
Vol 22 (1) ◽  
pp. 33-42
Author(s):  
◽  
Tajuddin Bantacut ◽  
Sapta Raharja
Keyword(s):  
System Approach ◽  
Added Value ◽  
Assessment Criteria ◽  
Cocoa Bean ◽  
Cocoa Beans ◽  
Bayes Method ◽  
Cocoa Products ◽  
Processed Products ◽  
Derivative Products

Abstract Utilization of cocoa bean to be a derivative products in industrial is wide enough, that it is necessary to determine the priority of the processed products development. This study aimed to determine the prospective processed cocoa products with a system approach using Bayes method and assessed the potential of added value by using Hayami method. Based on several assessment criteria indicated that chocolate bar is the priority product that needs to be developed and followed by several other processed products. This development was able to produce the added value of Rp 135.000 per kg of cocoa beans. Result indicated that by processing the cocoa beans into chocolate bar could provide a considerable income for the businessman.

SYSTEM APPROACH TO COAL PRODUCT QUALITY CONTROL

2017 ◽  
Vol 17 (6) ◽  
pp. 13-24
Author(s):  
E.V. Freydina ◽  
◽  
E.V. Freydina ◽  
A.A. Botvinnik ◽  
A.N. Dvornikova ◽  
...  
Keyword(s):  
Quality Control ◽  
Product Quality ◽  
System Approach ◽  
Product Quality Control ◽  
Coal Product

Sorption of Se (IV) from aqueous solutions with subsequent determination by X-ray fluorescence analysis

2020 ◽  
Vol 86 (10) ◽  
pp. 5-9
Author(s):  
D. G. Filatova ◽  
A. A. Arkhipenko ◽  
M. A. Statkus ◽  
V. V. Es’kina ◽  
V. B. Baranovskaya ◽  
...  
Keyword(s):  
Inductively Coupled Plasma ◽  
Fluorescence Analysis ◽  
Standard Samples ◽  
Phase Contact Time ◽  
Sorbent Phase ◽  
X Ray ◽  
Fundamental Parameters ◽  
Inductively Coupled ◽  
Subsequent Determination

An approach to sorptive separation of Se (IV) from solutions on a novel S,N-containing sorbent with subsequent determination of the analyte in the sorbent phase by micro-x-ray fluorescence method is presented. The sorbent copolymethylenesulfide-N-alkyl-methylenamine (CMA) was synthesized using «snake in the cage» procedure and proven to be stable in acid solutions. Conditions for quantitative extraction of Se (IV) were determined: sorption in 5 M HCl or 0.05 M HNO3 solutions when heated to 60°C, phase contact time being 1 h. The residual selenium content in the solution was determined by inductively coupled plasma mass spectrometry (ICP-MS) using 82Se isotope. The absence of selenium losses is proved and the mechanism of sorption interaction under specified conditions is proposed. The method of micro-x-ray fluorescence analysis (micro-RFA) with mapping revealed a uniform distribution of selenium on the sorbent surface. The possibility of determining selenium in the sorbent phase by micro-RFA is shown. When comparing the obtained results with the results of calculations by the method of fundamental parameters, it is shown the necessity of using standard samples of sorbates to obtain correct results of RFA determination of selenium in the sorbent phase.

UV spectroscopic method for determination of phenytoin in bulk and injection forms

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Quality Control ◽  
Spectrophotometric Method ◽  
Spectroscopic Method ◽  
Ich Guidelines ◽  
Precision And Accuracy ◽  
Routine Quality Control

Recent study was conducted to develop a simple UV spectrophotometric method to determine Phenytoin in bulk and injection form according to official requirement and validate as per ICH guidelines. λmax of Phenytoin was found 202 nm. Linearity existed perceived in the concentration assortment 2-8 μg/ml (r2 = 0.999) for the method. The method was validated pertaining to linearity, precision and accuracy studies, LOD and LOQ consistent with ICH guidelines. The existent method was establish to be simple, linear, precise, accurate as well as sensitive and can be applied for routine quality control enquiry for the analysis of Phenytoin in bulk and injection form.

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