scholarly journals Resection of a large primary left ventricle tumour by cardiac autotransplantation in a 2-month-old infant: a case report

Author(s):  
Yuhang Liu ◽  
Ning Wang ◽  
Ping Wen ◽  
Gengxu Zhou

Abstract Background Surgery is the fundamental method for the treatment of primary cardiac tumours. However, due to the inaccessibility of anatomy and the proximity of important structures, it is very difficult to completely resect tumours of the left atrium or left ventricle without damaging the normal tissues. Cardiac autotransplantation for the resection of cardiac tumours is carried out by taking out the heart from the body, resecting cardiac tumours, and then transplanting the heart back into the body. Case summary This article presents a successful case of cardiac autotransplantation for the complete resection of primary cardiac tumour in a 2-month-old infant and shares the noteworthy experience. Discussion Tumours located in the left atrium and left ventricle are difficult to be exposed because of their deep posterior location and proximity to important anatomical structures such as mitral valve and chordae tendineae. How to resect the tumours completely without damaging the normal tissues is a great challenge. This case proves that cardiac autotransplantation is a good solution for tumours that are difficult to be resected completely by orthotopic cardiac transplantation.

Author(s):  
Muralidhar Padala ◽  
Lazarina I. Gyoneva ◽  
Ajit P. Yoganathan

The Mitral Valve (MV) is the left atrioventricular valve that controls blood flow between the left atrium and the left ventricle (Fig 1A-B). It has four main components: (i) the mitral annulus – a fibromuscular ring at the base of the left atrium and the ventricle; (ii) two collagenous planar leaflets – anterior and posterior; (iii) web of chordae tendineae – classified into primary (inserting at the free edge of the leaflet), secondary (inserting into the base of the leaflet), tertiary (inserting into the annulus); and (iv) two papillary muscles that are part of the left ventricle. Normal function of the mitral valve involves a delicate force balance between different components of the valve.


Author(s):  
Kazem Rahimi

Mitral regurgitation (MR) is the reflux of blood from the left ventricle into the left atrium as a result of dysfunction of the mitral valve. MR can result from abnormalities of any part of the mitral valve apparatus (valve leaflets, annulus, chordae tendineae, and papillary muscles), or dilatation/disease of the left ventricle.


2017 ◽  
Vol 7 (4) ◽  
pp. 240-247
Author(s):  
O. V. Filatova ◽  
E. Ivanova ◽  
V. Chursina

We conducted a retrospective study of EchoCG from 33 males who had the myocardial infarction. Patients with a diagnosis of "neurocirculatory dystonia" (30 people) entered the control group. We studied the size of the left ventricle, the left atrium, the right ventricle, their relationship to each other, the mass of the myocardium and the mass index of the myocardium of the left ventricle. The study of the morphological structures of the heart revealed a change in the size of the left ventricle, the left atrium and the right ventricle in patients who had an acute myocardial infarction, manifested by an increase in the end-diastolic and end-systolic dimensions of the left ventricle, the left atrium, and the right ventricle. In 2/3 of the patients who had an acute myocardial infarction, the normal geometry of the left ventricle was observed. Around one-quarter of the patients had a concentric remodeling (24%), an eccentric hypertrophy of the left ventricle was the least common (15%). The heart of patients who had an acute myocardial infarction demonstrates a lower functionality being compared to the subjects in the control group. In these groups, the maximum value of the DAC / DDR ratio is observed, the ejection fraction is reduced. To a greater extent, the onset of acute myocardial infarction was determined by the size and mass of the left ventricular myocardium. Important meaning had also the body weight, BMI, surface area of the body, the size of the left atrium, and the right ventricle.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Cihan Gündoğan ◽  
Yunus Güzel ◽  
Canan Can ◽  
İhsan Kaplan ◽  
Halil Kömek

Objective. The aim of this study is to investigate the uptake of 68Ga-FAPI-04 in normal tissues and calculate standardized uptake values (SUVs) for various organs in the body. Methods. A total of 49 patients who underwent 68Ga-FAPI-04 PET/CT were included in our study. The following organs were identified on CT images: brain, parotid, and submandibular glands, palatine tonsils, thyroid, lymph nodes (if present), breasts, lungs, thymus, left ventricle walls, mediastinal blood pool, vertebral bone marrow, liver, spleen, pancreas, stomach, small and large intestines, adrenal glands, kidneys, uterus, testes, and prostate. Median, minimum, and maximum values (max) and average (avg) values of standard uptake value (SUV) of tissues and organs were calculated. Results. The accumulation of 68Ga-FAPI in normal organs showed variations. The cerebral/cerebellar cortex exhibited no 68Ga-FAPI uptake, while the scalp showed low uptake. Low uptake was also observed in the lung parenchyma, esophagus, left ventricle walls, nipple, and glandular breast tissue. In the abdominopelvic area, the pancreas exhibited low uptake, which was higher in the tail region. Low uptake was observed in the renal cortex. Intense 68Ga-FAPI uptake was observed throughout the uterus, which was higher in the corpus. There was no uptake of 68Ga-FAPI in the bone cortex and medulla. Conclusion. We determined the physiological uptake and SUVmax of FAPI-04 in different tissues and organs and created a guide for researchers.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Drasutiene ◽  
V Janusauskas ◽  
G Speziali ◽  
D Zakarkaite ◽  
M Budra ◽  
...  

Abstract Introduction Various minimally invasive mitral valve (MV) repair techniques are available to treat degenerative mitral regurgitation (MR). Transapical implantation of artificial chordae on a beating heart is performed using the NeoChord DS1000 device with real-time TEE guidance. Purpose 1)To assess preoperative and the mid-term follow-up echocardiographic data in patients after MV repair using the NeoChord DS1000 device; 2)to investigate the changes of left ventricle (LV), left atrium (LA) and mitral annulus dimensions during the follow-up period; 3)to assess the difference of baseline echocardiographic parameters between successful and not-successful (severe residual MR) MV repair groups; 4)to identify the preoperative echocardiographic variables that may be associated with recurrence of MR at mid-term follow. Methods All patients after transapical MV repair with Neochord implantation in Vilnius University hospital were prospectively entered into the study. The acquired preoperative and follow-up echocardiographic datasets were analysed. According to the residual MR at follow-up, patients were stratified to 2 groups: group A – successful durable MV repair (residual MR ≤2); group B – MV repair failure (recurrence of severe MR or reintervention). Values were expressed as Mean±SD. Univariable regression analysis was used to identify anatomical predictors of residual MR. Results 53 (70.67%) patients had a residual MR ≤2 (Group A) and 22 (29.33%) residual MR≥2+ (Group B) at 26±6 months follow-up. At baseline, Group B patients had significantly larger left ventricle end diastolic diameter (LVEDD) (mean difference 5.67±1.29mm, p<0.0001) left ventricle end systolic diameter (LVESD) (mean difference 4.08±1.57mm, p=0.012), LA volume index (mean difference 21.57±5.003 p<0.0001) and higher systolic pulmonary pressure values (mean difference 10.46±3.34, p<0.003) compared with group A. Overall, a significant reduction in LA volume index (mean change 15.69±4.15ml/m2, p<0.001), LA diameter (mean change 3.15±1.24, p=0.012), LV diameter (mean change in LVEDD 4.78±0.88mm p<0.000) was observed at 24 months follow up. There was no significant changes in MV annular parameters at follow up. Left atrium volume (OR 1.018; 95% CI 1.006–1.035; p=0.009), left atrium volume index (OR 1.038; 95% CI 1.013–1.072; p=0.010), LVEDD (OR 1.201; 95% CI 1.088–1.353; p=0.0008), LVESD (OR 1.122; 95% CI 1.02–1.248); p=0.0236) and sPAP (OR 1.418; 95% CI 1.139–2.016; p=0.0014) were all significantly associated with the worse outcome (MR >2) after mini-invasive MV repair in univariable regression analysis. Conclusions Minimaly invasive MV repair with Neochord system on beating heart is effective in patients with degenerative MR. Baseline echocardiographic characteristics predictive for a worse middle term outcome are mainly related to LV and LA remodeling. Reverse remodeling of LV and LA is observed during the follow-up period with no significant changes in MV annulus. Funding Acknowledgement Type of funding source: None


2009 ◽  
Vol 11 (3) ◽  
pp. 250-256 ◽  
Author(s):  
S. Caselli ◽  
E. Canali ◽  
M. L. Foschi ◽  
D. Santini ◽  
E. Di Angelantonio ◽  
...  

2013 ◽  
Vol 44 (5) ◽  
pp. e341-e342 ◽  
Author(s):  
Arnaud Rodriguez ◽  
François Roubertie ◽  
Matthieu Thumerel ◽  
Jacques Jougon

2021 ◽  
Vol 9 (10) ◽  
pp. 2339-2346
Author(s):  
Shivakumari Shivakumari ◽  
Vasudev A Chate ◽  
Shreevastha Shreevastha

The concept of Srotas and Srotodushti Lakshana has been very scientifically explained in the various context of Ayurveda literature. Detailed Srotas and Srotodushti Lakshana are according to Charaka Samhita Vimansthana assessment of Srotodushti Lakshana can be done by Pratyksha Pramana and in detail explanation. The Srotas play an important role in physiology and the pathogenesis of diseases in normal state; they regulate the physiolo- gy of the body and maintain the anatomical structures of dhatus. The influences of aetiology factors on Srotas can affect pathological manifestations. Considering this fact present study explores various aspects related to the Sro- tas, Srotodushti and Srotodushti Lakshana. Objectives-To assessment of Srotodushti Lakshana in Artavavaha Srotas through Clinical, biochemical, and radiological examination in Artavavaha Srotas. Methodology -The study was conducted under two headings, conceptual and survey study. Conceptual study all the concerned litera- ture were referred and analysed and for survey study, the Artvavaha Sroto Vikara observed and survey through face-face interview. -Hence it is concluded that the knowledge of Srotas is not only used in learning about the anatomy of the transport system of the body but also to understand their physiology and pathology. It can be as- sessed through clinical, biochemical, and radiological findings. Keywords: Srotas, Srotodushti Lakshana, Artavavaha Srotas,


2011 ◽  
Vol 5 ◽  
pp. 909-913
Author(s):  
Stanisław Ostrowski ◽  
Anna Marcinkiewicz ◽  
Anna Kośmider ◽  
Witold Pawłowski ◽  
Alicja Nowakowska ◽  
...  
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