Intimal thickening in the coronary arteries of infants and children as an indicator of risk factors for coronary heart disease

1990 ◽  
Vol 11 (suppl E) ◽  
pp. 53-60 ◽  
Author(s):  
E. Pesonen ◽  
R. Norio ◽  
J. Hirvonen ◽  
K. Karkola ◽  
V. Kuusela ◽  
...  
2019 ◽  
Vol 3 (12) ◽  
pp. 493-496
Author(s):  
Monitrya Nababan ◽  
Achmad Lefi ◽  
Djohar Nuswantoro

Objective: To determine the relationship of coronary heart disease traditional risk factors to the number of lesioned coronary arteries and calculate the relative risk. Methods: This study used an analytical research design with a retrospective cohort study design using patient catheterization report data. Data analysis was performed using the chi square test and relative risk in 449 individuals. Results: Based on the analysis results obtained p value 0.05 indicating no relationship between risk factors for coronary heart disease with the number of coronary arteries the lesions based on sex, history of hypertension and history of smoking. Conclusion: There is a relationship between age, history of diabetes mellitus, history of dyslipidemia and the number of coronary arteries that are lesions in patients with coronary heart disease and there is no relationship between sex, history of hypertension and smoking history with the number of coronary arteries that are lesions in patients with coronary heart disease. Keywords: single vessel disease; multivessel disease; coronary artery disease; risk factors CAD


2019 ◽  
pp. 138-147
Author(s):  
V. S. Arakelyan ◽  
A. R. Jane ◽  
N. A. Gidaspov ◽  
P. P. Kulichkov ◽  
N. V. Bortnikova

Introduction. According to the literature, 27 to 65 % of patients with abdominal aortic aneurysm also suffer from coronary heart disease. Mortality from coronary heart disease after surgical treatment for abdominal aortic aneurysm according to some data exceeds 20 %.Objective: improvement of results of treatment of patients with combined lesions of coronary arteries and aneurysm of the abdominal aortaSubjects and method. A retrospective analysis of case histories of 100 patients hospitalized in our clinic diagnosed with «abdominal aortic aneurysm» for examination. Of all patients, 37 % were diagnosed with significant coronary artery lesions. The average ejection fraction was 58.2 ± 5.4 %, 13 % of the study diagnosed significant violations of local myocardial contractility. 16 % of patients had previous myocardial infarction, 7 % – a permanent form of atrial fibrillation. 4 % of patients complained of chest pain during exercise. Hypertension was present in 100 % of patients, the average maximum systolic blood pressure was 176 ± 24.5 mmHg.Results. Hospital mortality was 2 % (all patients were non-operated on coronary arteries and had no significant coronary pathology). There were no significant complications (cardiac, neurological, respiratory) in the early postoperative period. The average length of hospital stay was 9.8 ± 1.99 bed days.Conclusions. Determination of cardiac status before surgery for abdominal aortic aneurysm is the most important moment of stratification of the risk of perioperative complications. Coronary angiography in patients with abdominal aortic aneurysm is a mandatory point of diagnosis, allowing to identify cardiac risk factors.


2013 ◽  
Author(s):  
Elena Malyuta ◽  
Tatiana Raskina ◽  
Olga Barbarash ◽  
Alexandr Kokov

2019 ◽  
Vol 70 (10) ◽  
pp. 3582-3586

Obstructive sleep apnoea syndrome (OSAS) increases the risk cardiovascular events regardless of the presence of previous cardiovascular disease. As both OSAS and coronary heart disease (CHD) have same risk factors it’s often difficult to quantify the proportion of each risk factor in developing cardiac events. The aim of this study was to evaluate the 10-year risk of developing a coronary heart disease (CHD) event or stroke in newly diagnosed OSAS patients. 65 patients diagnosed with OSAS over a period of four months in Oradea Sleep Laboratory were included. Demographic characteristics, anthropometric parameters, clinical and biochemical data, sleep disorder and daytime sleepiness assessment, results of polysomnography were collected in all patients. In 55 selected patients by age range from 34 to 74 years old, cardiovascular risk was assessed using Framingham score calculator. Statistical analysis was performed using SPSS-PC version 7.5 and Stata 10.The estimated 10-years risk of a CHD event was 18.97% (± 9.67) in all cases. It was higher in men (22.17% ± 9.24) compare to women (12.39% ± 6.92) and it was not significantly different by stages of OSAS severity (20.58% ±9.41 in patients with severe OSAS versus 15.4% in mild OSAS), suggesting that apnea hypopnea index is not a major confounding factor. Desaturation of oxygen is a better outcome to define the relation between OSAS and cardiovascular diseases. OSAS and cardiovascular risk factors increased risk for future adverse cardiovascular events related to the severity of oxygen desaturation. Keywords: obstructive sleep apnoea syndrome, cardiovascular events, risk factors, oxygen desaturation


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