scholarly journals Corrigendum to: A Phenomapping-Derived Tool to Personalise the Selection of Anatomical versus Functional Testing in Evaluating Chest Pain (ASSIST)

2022 ◽  
Keyword(s):  
Chest Pain ◽  
Functional Testing ◽  
Selection Of

scholarly journals COST-EFFICIENT SELECTION OF STRESS TEST FOR LOW-RISK CHEST PAIN

2015 ◽  
Vol 65 (10) ◽  
pp. A122
Author(s):  
Joseph Gibbs ◽  
Carlos Calle-Muller ◽  
Matthew Cerasale ◽  
Tarun Jain ◽  
Sagger Mawri ◽  
...  
Keyword(s):  
Chest Pain ◽  
Stress Test ◽  
Low Risk ◽  
Cost Efficient ◽  
Efficient Selection ◽  
Selection Of

Cardiac-specific immunoenzymometric assay of troponin I in the early phase of acute myocardial infarction

1993 ◽  
Vol 39 (6) ◽  
pp. 972-979 ◽  
Author(s):  
C Larue ◽  
C Calzolari ◽  
J P Bertinchant ◽  
F Leclercq ◽  
R Grolleau ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Chest Pain ◽  
Troponin I ◽  
Cross Reactivity ◽  
Control Group ◽  
Specificity And Sensitivity ◽  
Healthy Donors ◽  
One Step ◽  
Selection Of

Abstract The screening by immunoenzymometric assay (IEMA) of 784 monoclonal antibody (MAb) combinations resulted in the selection of an optimal pair of MAbs for measuring human cardiac troponin I (TnI). Using a one-step IEMA described here, we were able to detect TnI within the range of 0.2-20 micrograms/L in 30 min at room temperature. No cross-reactivity was observed with the skeletal isoforms of troponin up to a concentration of 500 micrograms/L. This assay was used to measure cardiac TnI in the plasma of 43 patients with acute myocardial infarction (AMI). TnI was detected relatively early after the onset of chest pain (4.3 +/- 2.1 h, mean +/- SD); the peak occurred after 12.2 +/- 4.6 h in a population that had undergone fibrinolysis. TnI disappearance was generally observed between 5 and 9 days after the onset of chest pain. No cardiac TnI could be detected in 145 healthy donors or in a control group of 6 patients (with skeletal damage or rhabdomyolysis). This assay allows a specific diagnosis of AMI in its early acute phase, with a high diagnostic specificity and sensitivity.

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