Inequalities in overall survival of oropharynx, oral cavity, and larynx cancers in Brazil

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
F S Menezes ◽  
A M B de Oliveira ◽  
T N Toporcov

Abstract Socioeconomic inequalities in the survival of head and neck cancer is a widespread concern in developing countries. In Brazil, there are severe social disparities that include access to healthcare. In this context, we investigated whether social inequalities impact the overall survival of patients diagnosed with larynx, oral cavity, and oropharynx cancers in São Paulo State (2000-2018). This hospital-based cohort study used data provided by the São Paulo Oncocentro Foundation (FOSP) in São Paulo State, Brazil. The 5-year overall survival (OS) was assessed by the Kaplan-Meier curves, log-rank tests, and Cox proportional hazard models to calculate the hazard ratio (HR). We considered a confidence level of 95% (95%CI) to indicate statistical significance. Out of the 816,393 cases recorded in the São Paulo State, a total of 37,191 cases occurred in larynx (n = 12,095), oral cavity (n = 12,858), and oropharynx (n = 12,238). The OS was 40.3%, 31.7%, and 23.6% for larynx, oral cavity, and oropharynx cancers, respectively. In multivariable Cox regression, formal education lower than 9 years increased the risk of death in oropharynx cancers (HR = 1.11; 95%CI= 1.05; 1.17), oral cavity cancers (HR = 1.06; 95%CI= 1.01; 1.12), and larynx cancers (HR = 1.09; 95%CI= 1.03; 1.16). The public healthcare assistance has shown to be a factor for a higher risk of death by 79% for oropharynx in comparison to private healthcare assistance, adjusted by age group, gender, clinical staging, and therapy modalities (chemotherapy, radiotherapy, and surgery). In conclusion, there is a remarkable social inequality at individual level in São Paulo State that poses a challenge to public the health in order to improve the overall survival in Brazilian patients. Key messages Social inequalities reduce the overall survival in oropharynx, oral cavity, and larynx cancers in São Paulo State, Brazil. Tackling social disparities is crucial since they play an essential role in the prognosis of Brazilian patients with oropharynx, oral cavity, and larynx cancers.

2020 ◽  
Author(s):  
Maria Angela Zaccarelli-Marino ◽  
Thalles Zaccarelli Balderi ◽  
Felipe Mingorance Crepaldi ◽  
Rudá Alessi ◽  
Marco Martins

Abstract Background: The epidemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) yielded intense respiratory illness clusters and has progressed rapidly into a pandemic. Objective: Evaluating the pre-existing conditions (rhinitis, sinusitis, pharyngitis, obstructive pulmonary diseases (OPD), conjunctivitis, dermatitis, and primary hypothyroidism (PH)) in residents exposed to long-term air pollutants and their higher risk of complications in case of infection with SARS-CoV-2. Methods: 2004 residents of both sexes, aged 8-72 years old, had responded to a home-based questionnaire. SARS-CoV-2 cases were collected from the Greater ABC Region, an industrial region of the São Paulo State, Brazil, part of the São Paulo Metropolitan Region. With a focus on the Capuava Petrochemical Complex influence area, using the combination of the AERMOD dispersion model with the Weather Research Forecast (WRF) meteorological model (2016), we evaluated the Greater ABC region. Atmospheric pollutant concentrations were analyzed in 2017 using meteorological data from 2005 to 2009, correlating this data with the research done from 2003 to 2005. Results: nitrogen dioxide (NO2), carbon monoxide (CO), particulate matter (PM10), sulfur dioxide (SO2), and Volatile organic compounds (VOCs) concentrations presented the highest correlations between the rhinitis, sinusitis, pharyngitis, OPD, conjunctivitis, dermatitis and PH odds and pollutant concentrations. Conclusion: We demonstrated that the closer the individuals live from the Petrochemical complex, the higher their risk of death from SARS-CoV-2. Given the asymptomatic characteristic of the disease in its initial development individuals and the risk of its complications, we suggest that the employees of chemical plants and residents living around industrial areas must be continuously evaluated for SARS-CoV-2.


2012 ◽  
Vol 28 (10) ◽  
pp. 1903-1914 ◽  
Author(s):  
Caroline Senicato ◽  
Marilisa Berti de Azevedo Barros

The aim of this was study was to assess social inequalities in health status and use of health services according to level of schooling in women. This was a cross-sectional population-based study with a sample of 508 women from 20 to 59 years of age living in Campinas, São Paulo State, Brazil (ISA-Camp 2008). Women with less schooling showed higher prevalence of hypertension, circulatory problems, headache, dizziness, obesity, common mental disorders, worse self-rated health, use of dental prosthesis, and visual impairment, but lower prevalence for use of eyeglasses. There were no differences between the two schooling strata in prevalence of medical visits in the previous two weeks, use of medicines in the three previous days, Pap smear, breast self-examination, clinical breast examination, hospitalizations and surgeries in the previous year, and rubella vaccination any time in life. The only significant differences were in use of dental services and mammograms. The results show social inequalities in various health indicators and equity in access to various components of the health services.


Author(s):  
Liliane Maria Guimarães de Pinho ◽  
Vera Lúcia Garcia ◽  
Maria Cezira Fantini Nogueira-Martins

Implementation of a multiprofessional residency in family health in a city of São Paulo state: perception of the first residents (2014-2016)


2017 ◽  
Vol 314 (3) ◽  
pp. 1675-1681
Author(s):  
Elvis J. França ◽  
Elisabete A. De Nadai Fernandes ◽  
Felipe Y. Fonseca ◽  
Marcelo R. L. Magalhães ◽  
Mariana L. O. Santos

Author(s):  
Raquel Cardoso de Souza ◽  
Aline Andrade Godoy ◽  
Fábio Kummrow ◽  
Thyago Leandro dos Santos ◽  
Carlos Jesus Brandão ◽  
...  

2021 ◽  
Vol 141 ◽  
pp. 110805
Author(s):  
Giancarlo Aquila ◽  
Wilson Toshiro Nakamura ◽  
Paulo Rotella Junior ◽  
Luiz Celio Souza Rocha ◽  
Edson de Oliveira Pamplona

Author(s):  
Thaís Silvana de Carvalho ◽  
Marcelo Adorna Fernandes ◽  
Frésia Ricardi-Branco ◽  
Aline Marcele Ghilardi ◽  
Bernardo de Campos Pimenta e Marque Peixoto ◽  
...  

Energies ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3964
Author(s):  
Laryssa Morais ◽  
Victor Nascimento ◽  
Silvio Simões ◽  
Jean Ometto

The urban population increase in the world, the economic expansion, and the rise in living standards associated with society’s habits and lifestyles accelerated the municipal solid waste (MSW) generation in undeveloped countries, such as in Brazil, in which the generation increased by 25% from 2012 to 2017. In the same period, the São Paulo state, the richest Brazilian state, increased its municipal solid waste generation by 51%. All this MSW needed to be collected and transported, and this process has a high economic and environmental cost. Therefore, this study aims to identify, using spatial analysis, the routes used by MSW trucks to estimate the distances traveled to dispose of the MSW on a regional scale considering all municipalities in the São Paulo state. The findings showed that the landfill numbers decrease, mainly individual ones, which receive MSW only from the city where it is located. Otherwise, the consortium landfills number is increasing, as well as the number of municipalities that share the same disposal site. Consequently, the distances to transport MSW from urban areas to final disposal sites increased by about 55% from 2012 to 2017, reaching 613 million kilometers during this period. This total distance is sufficient to make more than 12,806 laps on Earth and contribute to high fuel consumption and greenhouse gas emission.


Author(s):  
Fernando P. F. Zorzenon ◽  
Arthur F. Tomaseto ◽  
Matthew P. Daugherty ◽  
João R. S. Lopes ◽  
Marcelo P. Miranda

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