scholarly journals Finding Factors in Footfalls: Exploring the Factor Structure of Gait in Older Adults

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 657-657
Author(s):  
Michael Willden ◽  
Josh Palmer ◽  
Kristina Kowalski ◽  
Sandra Hundza ◽  
Stuart MacDonald

Abstract Gait is a reputed marker of global health spanning various bodily systems (MacDonald et al., 2017) and is a robust predictor of deleterious age-related outcomes (Van Kan et al., 2009). However, the sheer number of individual gait variables employed as predictors in the existing literature can obscure interpretations. To address this issue, researchers have explored the factor structure of gait indicators to explain variance in age-related gait performance, identifying disparate models characterized by three to five underlying latent gait constructs comprised of 8 to 23 indicators (Hollman et al., 2011; Lord et al., 2013). Beyond this heterogeneity, additional limitations characterizing this literature include solutions that assume statistical independence among gait constructs, as well as inclusion of severely multicollinear indicators. Using data from the Healthy Minds Healthy Bodies (HMHB) study, the present research focused upon replicating and contrasting previous factor analytic efforts. HMHB participants (n=128) were healthy community-dwelling adults (Mage=72.81±5.24 years; female=100). Gait indicators from a GAITRite computerized walkway were selected according to a priori theoretical rationale, compatibility with previous studies, and consideration of multicollinearity. Gait factor structure was initially analyzed using principal component analysis. Results indicate the presence of three latent gait domains reflecting pace, rhythm, and variability, accounting for over 82.4% of the variance in gait performance. Current proceedings involve implementing confirmatory factor analysis to compare competing gait models. Findings will address disparities across factor models in the gait literature, as well as discuss the optimal number of factors for describing the underlying dimensionality of gait.

2000 ◽  
Vol 12 (2) ◽  
pp. 163-172 ◽  
Author(s):  
Turan Ertan ◽  
Engin Eker

The purpose of this study was to examine the Geriatric Depression Scale (GDS) translated into Turkish for its reliability, discriminant validity, and factor structure in a sample of 276 community-dwelling elderly and 30 patients with major depression. One item (Item 5) was discovered to have conceptual difficulty for Turkish elderly and was transformed to negative form. Item 2 was transformed to positive form to keep the number of positive and negative items equal to that in the original GDS. A reasonable time stability with 1-week interval (r:.74) and a high level of internal consistency (α = .91) were observed. Student's t test resulted in a significant discriminant validity for the scale total score. Factor study with principal component analysis and varimax rotation gave rise to a structure with seven factors. Results of the same analysis with two factors were found to be easier to interpret. The first factor was composed of 19 items reflecting “depressive affect and thought content.” The other 11 items representing “decrease in motivation and cognitive functions” loaded in the second factor. In conclusion, the Turkish GDS was found to have reasonable time reliability, high internal consistency, and discriminant validity for Turkish elderly. Its two-factor structure can be used as an informative instrument for epidemiological studies, reflecting two main dimensions of depression in the elderly.


2016 ◽  
Vol 28 (1) ◽  
pp. 5-32 ◽  
Author(s):  
Malgorzata Sobol-Kwapinska ◽  
Aneta Przepiorka ◽  
Philip P Zimbardo

The purpose of the paper is to present the main findings on the factor structure of time perspective measured using the Polish version of the Zimbardo Time Perspective Inventory (Zimbardo and Boyd, 1999) in different age groups. A total of 2789 adults took part in the study. Confirmatory factor analysis of Zimbardo Time Perspective Inventory items was conducted in a group of respondents aged 18–78 years to verify the original five-factor structure. Separate principal component analyses were carried out for three age groups: 18–27, 28–39, and 40–65 years old. In the group of students, a fairly clear five-factor structure of time perspective was found. In the group of the oldest respondents, a three-factor structure emerged, which can be described as follows: Past-Negative combined with Present-Fatalistic, Past-Positive combined with Future, and a separate factor corresponding to the Present-Hedonistic scale. Differences in the factor structure of time perspective were interpreted in the context of developmental change.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 216-217
Author(s):  
Erika Friedmann ◽  
Nancy Gee ◽  
Eleanor Simonsick ◽  
Erik Barr ◽  
Barbara Resnick ◽  
...  

Abstract Successful aging depends on avoiding disease and disability, maintaining high physical and cognitive function, and psychological adaptation. Research examining the relationship of pet ownership (PO) or human-animal interaction (HAI) to human health supports contributions to these successful ag-ing-related outcomes at some point in the life-cycle, mostly in populations with diseases or disabili-ties. We examine the contributions of PO to maintaining physical capacity among generally healthy community-dwelling older participants in the Baltimore Longitudinal Study of Aging (BLSA). Partici-pants’ [N=637, mean age=68.3 years (SD=9.6), pet owners N=149] completed a standardized physi-cal function test battery (among other measures) every 1-4 years and a ten-year PO history. Linear mixed, or generalized linear mixed, models with time varying PO were used to examine change in successful aging-related outcomes over up to 13 years [mean=7.5, (SD=3.6)] according to PO. Physi-cal function declined across all domains examined, but was observed to be less severe with PO in overall physical performance (p<0.001), rapid gait speed (p=0.041), 400-meter walk time (p<0.001), and reported physical wellbeing (p=0.032). No differences were observed for grip strength (p=0.56), usual gait speed (p=0.07), and leisure time physical activity (p=0.26) after con-trolling for age. This study provides the first longitudinal evidence that PO may promote successful aging among community-dwelling healthy older adults by moderating age-related declines in physical functional status in late-life.


2019 ◽  
Vol 33 (4) ◽  
pp. 470-496 ◽  
Author(s):  
Antonella Somma ◽  
Serena Borroni ◽  
Laura E. Drislane ◽  
Christopher J. Patrick ◽  
Andrea Fossati

This study sought to characterize the factor structure of the Triarchic Psychopathy Measure (TriPM) using data from a sample of 1,082 community-dwelling Italian adults. Exploratory structural equation modeling (ESEM) was used to compare the fit of a bifactor model for each TriPM scale, in which specific-content factors were specified along with a general factor, with the fit of a single, general-factor model. Robust weighted least square (WLSMV) ESEM supported a bifactor latent structure of the TriPM items for all individual scales. When we jointly factor analyzed the 58 TriPM items, a WLSMV ESEM three-factor structure showed adequate fit; the three ESEM factors were akin to TriPM Boldness, Meanness, and Disinhibition theoretical dimensions, respectively, and could be effectively replicated across gender subgroups. Our findings support the three-factor structure of TriPM items, at least in Italian community-dwelling adults, and provide further evidence for the construct validity of the TriPM.


1994 ◽  
Vol 7 (1) ◽  
pp. 1-7 ◽  
Author(s):  
M.E. Nichols ◽  
K.J. Meador ◽  
D.W. Loring ◽  
L.W. Poon ◽  
G.M. Clayton ◽  
...  

Although numerous studies have focused on age-related changes in the nervous system, few have systematically assessed global neurologic examination changes, and even fewer have included the most elderly population, ie, the centenarians. To perform such a study, we developed a quantitative assessment that includes the major components of a standard bedside neurologic evaluation, with special emphasis on cognitive function. First, we demonstrated that the quantitated examination could correctly classify healthy controls and patients with stroke or dementia based on discriminant analysis. This examination was then applied to healthy community-dwelling elderly ranging from 60 to 108 years of age. Significant age-related neurobehavioral changes were apparent across even these most “successfully” aged groups. Analysis of the full pattern of cognitive and neurologic findings provided the most accurate assessment. Pathologic reflexes, reportedly associated with normal aging, occurred infrequently in this healthy geriatric population, suggesting that age-related changes in the neurologic examination may be more accurately interpreted when assessed in conjunction with cognitive status. This quantitative examination may be useful in future population-based studies of neurologic function in the aged.


2019 ◽  
Vol 105 (3) ◽  
pp. e628-e641
Author(s):  
Ferdinand Roelfsema ◽  
Peter Y Liu ◽  
Paul Y Takahashi ◽  
Rebecca J Yang ◽  
Johannes D Veldhuis

Abstract Background Aging is associated with diminished testosterone (Te) secretion, which may be attributed to Leydig cell dysfunction, decreased pituitary stimulation, and altered Te feedback. Objective To study all regulatory nodes—gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH) and Leydig cell—in the same cohort of healthy men. Study Design This was a placebo-controlled, blinded, prospectively randomized cross-over study in 40 men, age range 19 to 73 years, and body mass index (BMI) range 20 to 34.3 kg/m2. A submaximal dose of the GnRH antagonist ganirelix was used to assess outflow of GnRH, by calculating the difference between LH output during the control arm and ganirelix arm. Ketoconazole (a steroidogenic inhibitor) was used to estimate feedback, by the difference in LH output during the ketoconazole and control arm. High-dose ganirelix and repeated LH infusions were used to measure testicular responsivity. Blood sampling was performed at 10-minute intervals. Results There were age-related, but not body composition–related decreases in estimated GnRH secretion, the feedback strength of Te on LH, and Leydig cell responsivity to LH, accompanied by changes in approximate entropy. Bioavailable Te levels were negatively related to both age and computed tomography (CT)–estimated abdominal visceral mass (AVF), without interaction between these variables. The LH response to a submaximal dose of GnRH was independent of age and AVF. Conclusion Advancing age is associated with (1) attenuated bioavailable Te secretion caused by diminished GnRH outflow and not by decreased GnRH responsivity of the gonadotrope, (2) diminished testicular responsivity to infused LH pulses, and (3) partial compensation by diminished Te feedback on central gonadotropic regulation.


2015 ◽  
Vol 207 (5) ◽  
pp. 435-439 ◽  
Author(s):  
Anya Topiwala ◽  
Charlotte L. Allan ◽  
Vyara Valkanova ◽  
Enikoá Zsoldos ◽  
Nicola Filippini ◽  
...  

BackgroundThe contribution of education and intelligence to resilience against age-related cognitive decline is not clear, particularly in the presence of ‘normal for age’ minor brain abnormalities.MethodParticipants (n = 208, mean age 69.2 years, s.d. = 5.4) in the Whitehall II imaging substudy attended for neuropsychological testing and multisequence 3T brain magnetic resonance imaging. Images were independently rated by three trained clinicians for global and hippocampal atrophy, periventricular and deep white matter changes.ResultsAlthough none of the participants qualified for a clinical diagnosis of dementia, a screen for cognitive impairment (Montreal Cognitive Assessment (MoCA) <26) was abnormal in 22%. Hippocampal atrophy, in contrast to other brain measures, was associated with a reduced MoCA score even after controlling for age, gender, socioeconomic status, years of education and premorbid IQ. Premorbid IQ and socioeconomic status were associated with resilience in the presence of hippocampal atrophy.ConclusionsIndependent contributions from a priori risk (age, hippocampal atrophy) and resilience (premorbid function, socioeconomic status) combine to predict measured cognitive impairment.


2011 ◽  
Vol 18 (2) ◽  
pp. 286-294 ◽  
Author(s):  
Michelle C. Carlson ◽  
Jeanine M. Parisi ◽  
Jin Xia ◽  
Qian-Li Xue ◽  
George W. Rebok ◽  
...  

AbstractThis study examined whether participation in a variety of lifestyle activities was comparable to frequent participation in cognitively challenging activities in mitigating impairments in cognitive abilities susceptible to aging in healthy, community-dwelling older women. Frequencies of participation in various lifestyle activities on the Lifestyle Activities Questionnaire (LAQ) were divided according to high (e.g., reading), moderate (e.g., discussing politics), and low (e.g., watching television) cognitive demand. We also considered the utility of participation in a variety of lifestyle activities regardless of cognitive challenge. Immediate and delayed verbal recall, psychomotor speed, and executive function were each measured at baseline and at five successive exams, spanning a 9.5-year interval. Greater variety of participation in activities, regardless of cognitive challenge, was associated with an 8 to 11% reduction in the risk of impairment in verbal memory and global cognitive outcomes. Participation in a variety of lifestyle activities was more predictive than frequency or level of cognitive challenge for significant reductions in risk of incident impairment on measures sensitive to cognitive aging and risk for dementia. Our findings offer new perspectives in promoting a diverse repertoire of activities to mitigate age-related cognitive declines. (JINS, 2012, 18, 286–294)


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S531-S531
Author(s):  
Leah N Smith ◽  
Jessica H Helphrey ◽  
Jennifer Sawyer ◽  
Leigh A Fierro ◽  
Ben K Mokhtari ◽  
...  

Abstract Numerous studies have found off-topic verbosity occurs more frequently in older adults than younger adults. Previous theories have attributed this to age-related decline, emotion recognition, and communication style. Previous research has linked lower loneliness with more off-topic verbosity; however, the precise nature of this relationship remains unclear. Loneliness has been defined as an inconsistency between an individual’s actual and desired social relationships, and previous research has found that loneliness is associated with lower cognitive and social outcomes among diverse populations including older adults. The purpose of this study was to investigate the relationship between loneliness and off-topic verbosity among older adults. Healthy, community dwelling older adult participants (N = 82; age 60-99, M = 76.66, SD = 8.52) completed the Three-Item Loneliness Scale and provided a verbal sample in which they recounted an autobiographical memory (a vacation) and a procedural memory (how to make a breakfast); the verbal samples were transcribed and rated by three independent judges. In contrast with previous research, results found that loneliness was associated with a greater tendency to engage in tangential verbal topics. This suggests that social factors such as loneliness may impact the way some older adults express themselves verbally.


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