scholarly journals Lifestyle Activities and Memory: Variety May Be the Spice of Life. The Women's Health and Aging Study II

2011 ◽  
Vol 18 (2) ◽  
pp. 286-294 ◽  
Author(s):  
Michelle C. Carlson ◽  
Jeanine M. Parisi ◽  
Jin Xia ◽  
Qian-Li Xue ◽  
George W. Rebok ◽  
...  
Keyword(s):  
Verbal Memory ◽  
Cognitive Abilities ◽  
Cognitive Aging ◽  
Community Dwelling ◽  
Cognitive Outcomes ◽  
Age Related ◽  
Aging Study ◽  
Cognitive Challenge ◽  
Lifestyle Activities ◽  
Healthy Community

AbstractThis study examined whether participation in a variety of lifestyle activities was comparable to frequent participation in cognitively challenging activities in mitigating impairments in cognitive abilities susceptible to aging in healthy, community-dwelling older women. Frequencies of participation in various lifestyle activities on the Lifestyle Activities Questionnaire (LAQ) were divided according to high (e.g., reading), moderate (e.g., discussing politics), and low (e.g., watching television) cognitive demand. We also considered the utility of participation in a variety of lifestyle activities regardless of cognitive challenge. Immediate and delayed verbal recall, psychomotor speed, and executive function were each measured at baseline and at five successive exams, spanning a 9.5-year interval. Greater variety of participation in activities, regardless of cognitive challenge, was associated with an 8 to 11% reduction in the risk of impairment in verbal memory and global cognitive outcomes. Participation in a variety of lifestyle activities was more predictive than frequency or level of cognitive challenge for significant reductions in risk of incident impairment on measures sensitive to cognitive aging and risk for dementia. Our findings offer new perspectives in promoting a diverse repertoire of activities to mitigate age-related cognitive declines. (JINS, 2012, 18, 286–294)

scholarly journals EXPLORING SEX DIFFERENCES IN COGNITION IN OLDER BLACKS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S543-S543
Author(s):  
DeAnnah R Byrd ◽  
Roland J Thorpe ◽  
Keith E Whitfield
Keyword(s):  
Sex Differences ◽  
Black Women ◽  
Black Men ◽  
Verbal Memory ◽  
Cognitive Aging ◽  
Later Life ◽  
Cognitive Change ◽  
Community Dwelling ◽  
Cognitive Outcomes ◽  
Future Research

Abstract Previous literature suggest that women experience more dementia than men. However, it is unclear what accounts for these differences and whether sex differences exist among Blacks over time. We hypothesize that Black women will have worse cognitive outcomes than men and smoking may potentially explain these differences. Longitudinal data from the Baltimore Study of Black Aging-Patterns of Cognitive Aging was used to assess cognitive change over 33 months in five domains. The sample consisted of 602 community-dwelling Blacks, aged 48-92 years at baseline and 450 at follow-up. Findings indicated that Black women reported better vocabulary, working and verbal memory than Black men, controlling for age, education, smoking, and health status. These findings suggest that Black women may have some cognitive advantages in mid to later life compared to Black men. Future research should continue exploring longitudinal sex differences in cognitive domains among Blacks and the underlying drivers of these differences.

Cognitive Aging in a Precision Sport Context

1996 ◽  
Vol 1 (3) ◽  
pp. 166-179 ◽  
Author(s):  
Bo Molander ◽  
Lars Bäckman
Keyword(s):  
Older Adult ◽  
Cognitive Abilities ◽  
Cognitive Aging ◽  
Motor Performance ◽  
Intervention Programs ◽  
Laboratory Studies ◽  
High Arousal ◽  
Memory And Attention ◽  
Age Related ◽  
Principal Finding

Highly skilled miniature golf players were examined in a series of field and laboratory studies. The principal finding from these studies is that young and young adult players (range = 15-38 years) score equally well or better in competition than in training whereas older adult players (range = 46-73 years) perform worse in competitive events than under training conditions. It was also found that the impairment in motor performance on the part of the older players is associated with age-related deficits in basic cognitive abilities, such as memory and attention. These results support the hypothesis that older players may be able to compensate for age-related deficits under relaxed conditions, but not under conditions of high arousal. The possibility of improving the performance of the older players in stressful situations by means of various intervention programs is discussed.

Impact of Personality on Cognitive Aging: A Prospective Cohort Study

2016 ◽  
Vol 22 (7) ◽  
pp. 765-776 ◽  
Author(s):  
Richard J. Caselli ◽  
Amylou C. Dueck ◽  
Dona E.C. Locke ◽  
Bruce R. Henslin ◽  
Travis A. Johnson ◽  
...  
Keyword(s):  
Verbal Memory ◽  
Cognitive Aging ◽  
Neuropsychological Testing ◽  
Personality Factors ◽  
Continuous Variables ◽  
Memory Decline ◽  
Age Related ◽  
Executive Skills ◽  
Visuospatial Skills ◽  
Visuospatial Perception

AbstractObjectives: The aim of this study was to assess the association between personality factors and age-related longitudinal cognitive performance, and explore interactions of stress-proneness with apolipoprotein E (APOE) ɛ4, a prevalent risk factor for Alzheimer’s disease (AD). Methods: A total of 510 neuropsychiatrically healthy residents of Maricopa County recruited through media ads (mean age 57.6±10.6 years; 70% women; mean education 15.8±2.4 years; 213 APOE ɛ4 carriers) had neuropsychological testing every 2 years (mean duration follow-up 9.1±4.4 years), and the complete Neuroticism Extraversion Openness Personality Inventory-Revised. Several tests were administered within each of the following cognitive domains: memory, executive skills, language, visuospatial skills, and general cognition. Primary effects on cognitive trajectories and APOE ɛ4 interactions were ascertained with quadratic models. Results: With personality factors treated as continuous variables, Neuroticism was associated with greater decline, and Conscientiousness associated with reduced decline consistently across tests in memory and executive domains. With personality factors trichotomized, the associations of Neuroticism and Conscientiousness were again highly consistent across tests within memory and to a lesser degree executive domains. While age-related memory decline was greater in APOE ɛ4 carriers as a group than ɛ4 noncarriers, verbal memory decline was mitigated in ɛ4 carriers with higher Conscientiousness, and visuospatial perception and memory decline was mitigated in ɛ4 carriers with higher Openness. Conclusions: Neuroticism and Conscientiousness were associated with changes in longitudinal performances on tests sensitive to memory and executive skills. APOE interactions were less consistent. Our findings are consistent with previous studies that have suggested that personality factors, particularly Neuroticism and Conscientiousness are associated with cognitive aging patterns. (JINS, 2016, 22, 765–776)

scholarly journals Increasingly capable at the ripe old age? Cognitive abilities from 2004 to 2013 in Germany, Spain, and Sweden

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254038
Author(s):  
Julia Grasshoff ◽  
Johannes Beller ◽  
Beatrice G. Kuhlmann ◽  
Siegfried Geyer
Keyword(s):  
Old Age ◽  
Cognitive Abilities ◽  
Cognitive Aging ◽  
Age Groups ◽  
Good Health ◽  
Cohort Effects ◽  
Educational Systems ◽  
Age Related ◽  
Life Years ◽  
Starting Point

Background Life expectancy is increasing in most high-income countries, but gains in life years are maximized if spent in good health and if cognitive abilities are maintained until old age. Age-related decline of cognitive abilities does nevertheless occur, but the pace of decline is decisive. This was the starting point for our study that aims to examine cohort effects of cognitive aging in women and men in Germany, Spain and Sweden by analyzing changes from 2004 to 2013 by estimating cohort effects within age groups starting from the age of 50 years. Methods A cohort study was conducted that was based on data of the surveys 2004 (N = 6,081) and 2013 (N = 8,650) from the Survey of Health, Ageing and Retirement in Europe (SHARE). The analyses were based on data of female and male respondents aged 50 years and older. Age-specific means of verbal fluency and delayed recall from the German, Spanish and Swedish samples were the cognitive domains considered in the study. Results In both domains of cognitive ability the achievements in the later surveys were higher than in the earlier ones. This was found in all countries, abut achievement levels increased markedly in the German and the Spanish samples, while the scores of the Swedish samples were not significantly different. While the highest scores were found for Sweden, Germany ranked in the middle and the lowest scores were found in the Spanish samples. Over time, the scores of the German samples approached those of Sweden. Conclusions From the first to the second survey, improvements of older adults’ cognitive abilities were found for all countries considered. This may indicate improvements of the underlying educational systems, but also increasingly stimulating general living conditions.

scholarly journals Pet Ownership and Longitudinal Change in Physical Function: Evidence From the BLSA

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 216-217
Author(s):  
Erika Friedmann ◽  
Nancy Gee ◽  
Eleanor Simonsick ◽  
Erik Barr ◽  
Barbara Resnick ◽  
...  
Keyword(s):  
Gait Speed ◽  
Successful Aging ◽  
Leisure Time Physical Activity ◽  
Psychological Adaptation ◽  
Community Dwelling ◽  
Longitudinal Change ◽  
Pet Ownership ◽  
Age Related ◽  
Animal Interaction ◽  
Healthy Community

Abstract Successful aging depends on avoiding disease and disability, maintaining high physical and cognitive function, and psychological adaptation. Research examining the relationship of pet ownership (PO) or human-animal interaction (HAI) to human health supports contributions to these successful ag-ing-related outcomes at some point in the life-cycle, mostly in populations with diseases or disabili-ties. We examine the contributions of PO to maintaining physical capacity among generally healthy community-dwelling older participants in the Baltimore Longitudinal Study of Aging (BLSA). Partici-pants’ [N=637, mean age=68.3 years (SD=9.6), pet owners N=149] completed a standardized physi-cal function test battery (among other measures) every 1-4 years and a ten-year PO history. Linear mixed, or generalized linear mixed, models with time varying PO were used to examine change in successful aging-related outcomes over up to 13 years [mean=7.5, (SD=3.6)] according to PO. Physi-cal function declined across all domains examined, but was observed to be less severe with PO in overall physical performance (p<0.001), rapid gait speed (p=0.041), 400-meter walk time (p<0.001), and reported physical wellbeing (p=0.032). No differences were observed for grip strength (p=0.56), usual gait speed (p=0.07), and leisure time physical activity (p=0.26) after con-trolling for age. This study provides the first longitudinal evidence that PO may promote successful aging among community-dwelling healthy older adults by moderating age-related declines in physical functional status in late-life.

The Relevance of Cognitive Aging Research to Warning Label Design

1997 ◽  
Vol 41 (2) ◽  
pp. 1368-1368
Author(s):  
Gabriel K. Rousseau ◽  
Nina Lamson ◽  
Wendy A. Rogers
Keyword(s):  
Older Adults ◽  
Cognitive Abilities ◽  
Cognitive Aging ◽  
Color Discrimination ◽  
Warning Label ◽  
Aging Research ◽  
Individual Difference Variables ◽  
Age Related ◽  
The Impact ◽  
Age Related Changes

A variety of individual difference variables affect whether someone notices, encodes, comprehends, and complies with a product warning label. Failures at any of these stages reduce the effectiveness of warnings. Development of effective warnings must be based on understanding the characteristics of the product user. As the population grows older, consideration of age-related changes in perceptual and cognitive abilities becomes more relevant to the warning designer. Aging researchers have identified a variety of declines and changes in vision (e.g., acuity, contrast sensitivity, and color discrimination) and memory (e.g., working memory and prospective memory). By considering the abilities of the product user, the impact of age-related changes may be minimized. Based on cognitive aging research and theory, we will make recommendations about how designers can increase the effectiveness of warnings for older adults.

scholarly journals MULTI-OMICS ANALYSIS IDENTIFIES GENE NETWORKS ASSOCIATED WITH COGNITIVE AGING AND ALZHEIMER’S DISEASE

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S587-S588
Author(s):  
Catherine Kaczorowski ◽  
Sarah Heuer ◽  
Chris Gaiteri ◽  
Catherine Kaczorowski
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Individual Differences ◽  
Cognitive Aging ◽  
Gene Networks ◽  
Cognitive Outcomes ◽  
Transcriptional Networks ◽  
Biological Processes ◽  
Mouse Population ◽  
Age Related

Abstract Alzheimer’s disease (AD) is the leading cause of age-related dementia, yet no treatment exists. AD is heterogeneous, and is resultant of the dysregulation of many genetic and biological processes. To decipher this complexity, we leveraged the first translational mouse population of AD to identify 15 gene networks related to individual differences in cognitive outcomes. Using QTL mapping, we also identified a novel putative driver of a module, Gstk1, highly conserved in humans that also significantly correlated with memory outcomes. Together, these transcriptional networks provide new mechanistic insight into the biological processes that regulate individual differences in cognitive function across a genetically diverse population. We could identify how demographics (age, sex, causal AD mutations) influence these modules and how they relate to cognitive outcomes. Finally, the high degree of conservation between our mouse modules to human modules reflects the translatability of our model to human AD, adding to its face validity.

Abstract MP88: Fetuin-A, a Vascular Biomarker of Cognitive Decline in Older Adults

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Gail A Laughlin ◽  
Linda K McEvoy ◽  
Elizabeth Barrett-Connor ◽  
Lori B Daniels ◽  
Joachim H Ix
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Cognitive Decline ◽  
Vascular Disease ◽  
Sex Education ◽  
Cognitive Aging ◽  
Community Dwelling ◽  
Fetuin A ◽  
High Functioning ◽  
Age Related

Objectives: The contribution of vascular disease to neurocognitive decline is now widely recognized. Fetuin-A is an abundant plasma protein known to predict vascular disease. Prior studies have shown that fetuin-A levels are lower in patients with Alzheimer’s disease in direct proportion to the severity of cognitive impairment; however, their association with normal cognitive aging is unknown. We evaluated the association of serum fetuin-A levels with cognitive function in relatively high-functioning, community-dwelling older adults from the Rancho Bernardo Study. Methods: This is a population-based study of 1382 older adults (median age 75) who had plasma fetuin-A levels and cognitive function evaluated in 1992-96; 855 had repeat cognitive function assessment a median of 4 years later. Results: Adjusting for age, sex, education, and depression, higher levels of fetuin-A were associated with better baseline performance on the Mini-Mental Status Exam (MMSE) (P=0.012) and a tendency for better Trails Making B scores (P=0.066). In longitudinal analyses, the likelihood of a major decline (highest decile of change) in Trails B was 29% lower (P=0.010) for each SD higher baseline fetuin-A level; odds of major decline in MMSE was 42% lower (P=0.005) per SD higher fetuin-A for individuals with no known CVD, but were not related to fetuin-A in those with CVD (P=0.33). Fetuin-A was not related to Category Fluency performance. Results did not vary by sex and were not explained by numerous vascular risk factors and comorbidities. Conclusions: Higher plasma fetuin-A concentrations are associated with better performance on tests of global cognitive function and executive function and with reduced likelihood of major decline in these cognitive abilities over a 4-year period. These observations are consistent with the hypothesis that higher fetuin-A protects against cognitive decline in relatively high functioning older adults, although this may be less apparent in those with established vascular disease. Fetuin-A may serve as a biological link between vascular disease and normal age-related cognitive decline.

scholarly journals Differential associations of functional and cognitive health outcomes with pre-frailty and frailty states in community-dwelling older adults

2018 ◽  
Vol 25 (8) ◽  
pp. 1057-1063 ◽  
Author(s):  
Caitlin Sleight ◽  
Roee Holtzer
Keyword(s):  
Older Adults ◽  
New York ◽  
Health Outcomes ◽  
Verbal Memory ◽  
Community Dwelling ◽  
Functional Health ◽  
Targeted Interventions ◽  
Health Decline ◽  
Age Related ◽  
Perceived Difficulty

This study examined associations of pre-frailty and frailty states with cognitive and functional health outcomes among community-residing older adults ( N = 457) in the Bronx, New York. Results: older adults who met criteria for frailty demonstrated poorer performance in attention, verbal memory, and overall global cognitive functioning compared to healthy controls. Moreover, pre-frail and frail older adults had significantly worse health outcomes including greater perceived difficulty with lower and upper extremity functioning and perceived limitations in completing daily activities, suggesting the need for targeted interventions in the community that may ameliorate age-related health decline.

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