scholarly journals Long-term Memory Response After a Single Intramuscular Rabies Booster Vaccination 10–24 Years After Primary Immunization

2021 ◽  
Author(s):  
Cornelis A De Pijper ◽  
Annefleur C Langedijk ◽  
Sanne Terryn ◽  
Steven Van Gucht ◽  
Martin P Grobusch ◽  
...  
Keyword(s):  
Booster Vaccination ◽  
Long Term Memory ◽  
Published Data ◽  
Primary Immunization ◽  
Term Memory ◽  
Booster Immunization ◽  
Memory Response ◽  
Antibody Titers ◽  
Exposure Prophylaxis

Abstract Background Published data regarding long-lasting immunological rabies memory after pre-exposure prophylaxis (PrEP) are scarce. We tested the hypothesis that rabies booster immunization elicits rapid anamnestic responses. Methods For this observational study, we included participants who had received PrEP 10–24 years before inclusion. We measured rabies antibody titers before, and on days 3, 7, and 14 after a single intramuscular booster. Results All 28 participants responded adequately regardless of route of administration or 2-dose vs 3-dose PrEP regimen. Conclusion Rabies immunological memory is reactivated within 7 days after a single intramuscular booster immunization, even when administered 10–24 years after PrEP.

Protein profile of scorpion venom from Hottentotta rugiscutis and its immunogenic potential in inducing long term memory response

Toxicon ◽  
2021 ◽  
Author(s):  
Kambaiah Nagaraj Santhosh ◽  
Dattatreya Pavana ◽  
Balakrishna Rao Shruthi ◽  
Nayaka Boramuthi Thippeswamy
Keyword(s):  
Protein Profile ◽  
Scorpion Venom ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Response

Complement and natural antibody are required in the long-term memory response to influenza virus

Vaccine ◽  
2008 ◽  
Vol 26 ◽  
pp. I86-I93 ◽  
Author(s):  
Santiago Fernandez Gonzalez ◽  
Jerome Priyantha Jayasekera ◽  
Michael C. Carroll
Keyword(s):  
Influenza Virus ◽  
Natural Antibody ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Response

The role of complement and natural antibody in the long-term memory response to influenza virus

2008 ◽  
Vol 45 (16) ◽  
pp. 4142
Author(s):  
Santiago F. Gonzalez ◽  
Jerome Jayasekera ◽  
Michael Carroll
Keyword(s):  
Influenza Virus ◽  
Natural Antibody ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Response

scholarly journals Long-Term Immunological Memory Induced by Recombinant Oral Salmonella Vaccine Vectors

2000 ◽  
Vol 68 (7) ◽  
pp. 4370-4373 ◽  
Author(s):  
James J. Kohler ◽  
Latha Pathangey ◽  
Adnan Hasona ◽  
Ann Progulske-Fox ◽  
Thomas A. Brown
Keyword(s):  
Immune Responses ◽  
Long Term Memory ◽  
Primary Immunization ◽  
Recall Response ◽  
Term Memory ◽  
Hemagglutinin Gene ◽  
Serovar Typhimurium ◽  
Residual Response ◽  
Vaginal Wash

ABSTRACT We have previously shown that Salmonella entericaserovar Typhimurium expressing the hagB hemagglutinin gene from Porphyromonas gingivalis can induce primary and recall immune responses in serum and secretions in mice; however, the longevity of memory induced by oral Salmonella carriers has not been adequately demonstrated. In this study, we examined the capacity of mice to mount a recall response 52 weeks after primary immunization. Recall responses were seen in serum immunoglobulin G (IgG) and IgA following boosting at week 52, and in most cases, they were equal to or greater than the primary responses. Significant mucosal IgA recall responses in saliva and vaginal wash were also detected following boosting at week 52. In addition, there was a considerable residual response in secretions at week 51, prior to boosting. These results indicate that oral Salmonellavectors can induce long-term memory to recombinant HagB and are particularly effective at inducing long-lasting mucosal responses as well as at inducing the capacity for mucosal recall responses.

scholarly journals Ferritin nanoparticle based SARS-CoV-2 RBD vaccine induces persistent antibody response and long-term memory in mice

2020 ◽  
Author(s):  
Wenjun Wang ◽  
Baoying Huang ◽  
Yanping Zhu ◽  
Wenjie Tan ◽  
Mingzhao Zhu
Keyword(s):  
Antibody Response ◽  
Memory B Cells ◽  
Long Term Memory ◽  
Recall Response ◽  
Term Memory ◽  
Vaccine Candidates ◽  
Memory Response ◽  
Post Immunization ◽  
Antibody Persistence

ABSTRACTSince the outbreak of COVID-19, over 200 vaccine candidates have been documented and some of them have advanced to clinical trials with encouraging results. However, the antibody persistence over 3 months post immunization and the long-term memory have been rarely reported. Here, we report that a ferritin nanoparticle based SARS-CoV-2 RBD vaccine induced in mice an efficient antibody response which lasts for at least 7 months post immunization. Significantly higher number of memory B cells were maintained and a significantly higher level of recall response was induced upon antigen challenge. Thus, we believe our current study provide the first information about the long-term antibody persistence and memory response of a COVID-19 vaccine. This information would be also timely useful for the development and evaluation of other vaccines.

Conceptual short-term memory (CSTM) supports core claims of Christiansen and Chater

2016 ◽  
Vol 39 ◽  
Author(s):  
Mary C. Potter
Keyword(s):  
Working Memory ◽  
Rapid Serial Visual Presentation ◽  
Language Comprehension ◽  
Short Term Memory ◽  
Visual Presentation ◽  
Long Term Memory ◽  
Short Term ◽  
Term Memory ◽  
Use Of Knowledge

AbstractRapid serial visual presentation (RSVP) of words or pictured scenes provides evidence for a large-capacity conceptual short-term memory (CSTM) that momentarily provides rich associated material from long-term memory, permitting rapid chunking (Potter 1993; 2009; 2012). In perception of scenes as well as language comprehension, we make use of knowledge that briefly exceeds the supposed limits of working memory.

Comparison of Auditory, Language, Memory, and Attention Abilities in Children With and Without Listening Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 710-727
Author(s):  
Beula M. Magimairaj ◽  
Naveen K. Nagaraj ◽  
Alexander V. Sergeev ◽  
Natalie J. Benafield
Keyword(s):  
Auditory Processing ◽  
Short Term Memory ◽  
Group Differences ◽  
Long Term Memory ◽  
Short Term ◽  
Significant Group ◽  
Term Memory ◽  
Memory And Attention ◽  
Speed And Accuracy

Objectives School-age children with and without parent-reported listening difficulties (LiD) were compared on auditory processing, language, memory, and attention abilities. The objective was to extend what is known so far in the literature about children with LiD by using multiple measures and selective novel measures across the above areas. Design Twenty-six children who were reported by their parents as having LiD and 26 age-matched typically developing children completed clinical tests of auditory processing and multiple measures of language, attention, and memory. All children had normal-range pure-tone hearing thresholds bilaterally. Group differences were examined. Results In addition to significantly poorer speech-perception-in-noise scores, children with LiD had reduced speed and accuracy of word retrieval from long-term memory, poorer short-term memory, sentence recall, and inferencing ability. Statistically significant group differences were of moderate effect size; however, standard test scores of children with LiD were not clinically poor. No statistically significant group differences were observed in attention, working memory capacity, vocabulary, and nonverbal IQ. Conclusions Mild signal-to-noise ratio loss, as reflected by the group mean of children with LiD, supported the children's functional listening problems. In addition, children's relative weakness in select areas of language performance, short-term memory, and long-term memory lexical retrieval speed and accuracy added to previous research on evidence-based areas that need to be evaluated in children with LiD who almost always have heterogenous profiles. Importantly, the functional difficulties faced by children with LiD in relation to their test results indicated, to some extent, that commonly used assessments may not be adequately capturing the children's listening challenges. Supplemental Material https://doi.org/10.23641/asha.12808607

Retrieval from Memory or Procedural Strategies for Addition Problems

2011 ◽  
Vol 70 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Muriel Fanget ◽  
Catherine Thevenot ◽  
Caroline Castel ◽  
Michel Fayol
Keyword(s):  
Reaction Times ◽  
Long Term Memory ◽  
Verbal Reports ◽  
Term Memory ◽  
Simple Addition ◽  
Memory Traces ◽  
Addition Problem ◽  
Retrieval From Memory ◽  
Calculation Procedures

In this study, we used a paradigm recently developed ( Thevenot, Fanget, & Fayol, 2007 ) to determine whether 10-year-old children solve simple addition problems by retrieval of the answer from long-term memory or by calculation procedures. Our paradigm is unique in that it does not rely on reaction times or verbal reports, which are known to potentially bias the results, especially in children. Rather, it takes advantage of the fact that calculation procedures degrade the memory traces of the operands, so that it is more difficult to recognize them when they have been involved in the solution of an addition problem by calculation rather than by retrieval. The present study sharpens the current conclusions in the literature and shows that, when the sum of addition problems is up to 10, children mainly use retrieval, but when it is greater than 10, they mainly use calculation procedures.

The Acute Effect of Alcohol on Various Memory Processes

2010 ◽  
Vol 24 (4) ◽  
pp. 249-252 ◽  
Author(s):  
Márk Molnár ◽  
Roland Boha ◽  
Balázs Czigler ◽  
Zsófia Anna Gaál
Keyword(s):  
Low Dose ◽  
Short Term Memory ◽  
Acute Effect ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Processes ◽  
Different Types ◽  
The Brain ◽  
Legal Consequences

This review surveys relevant and recent data of the pertinent literature regarding the acute effect of alcohol on various kinds of memory processes with special emphasis on working memory. The characteristics of different types of long-term memory (LTM) and short-term memory (STM) processes are summarized with an attempt to relate these to various structures in the brain. LTM is typically impaired by chronic alcohol intake but according to some data a single dose of ethanol may have long lasting effects if administered at a critically important age. The most commonly seen deleterious acute effect of alcohol to STM appears following large doses of ethanol in conditions of “binge drinking” causing the “blackout” phenomenon. However, with the application of various techniques and well-structured behavioral paradigms it is possible to detect, albeit occasionally, subtle changes of cognitive processes even as a result of a low dose of alcohol. These data may be important for the consideration of legal consequences of low-dose ethanol intake in conditions such as driving, etc.

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