scholarly journals Telemedicine usage via WeChat for Children with Congenital Heart Disease Preoperatively During COVID-19 Pandemic: A Retrospective Analysis

2021 ◽  
Author(s):  
Qi-Liang Zhang ◽  
Wen-Peng Xie ◽  
Yu-Qing Lei ◽  
Hua Cao ◽  
Qiang Chen
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Ductus Arteriosus ◽  
Depression Scale ◽  
Median Score ◽  
Septal Defects ◽  
Self Rating ◽  
Tract Infections

Abstract Background During the COVID-19 pandemic, parents of infants having medical problem face challenges of insufficient medical resources at home. The purpose of this study was to investigate the effect of WeChat-based telehealth services on the preoperative follow-up of infants with congenital heart disease (CHD) during the COVID-19 pandemic. Methods This study retrospectively analyzed the medical records of 190 infants with CHD who underwent remote follow-up via WeChat from December 2019 to May 2020 in Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University. In addition, the psychological benefits of WeChat on the parents of these infants were analyzed. Results In total, 190 infants were involved in this study, including 72 cases of ventricular septal defects, 42 cases of patent ductus arteriosus, 55 cases of atrial septal defects, 3 cases of tetralogy of Fallot, 2 cases of endocardial cushion defects, 12 cases of pulmonary stenosis, 2 cases of total anomalous pulmonary venous connection and 2 cases of aortic arch constriction. During the follow-up period, 48 infants who received surgical indications were hospitalized in time for surgical treatment. It was recommended that 10 infants with respiratory tract infections be treated in local hospitals through the WeChat platform. We provided feeding guidance to 28 infants with dysplasia through the WeChat platform. The psychological evaluation results of parents showed that the median score and range of Self-Rating Depression Scale (SDS) scores were 42 and 32-58, respectively. Nine parents (4.7%) were clinically depressed, while the majority had mild depression. The median score and range of Self-Rating Anxiety Scale (SAS) scores were 44 and 31-59, respectively. Twenty parents (10.5%) had clinical anxiety, while the rest had mild anxiety. Conclusion During the COVID-19 pandemic, follow-up management and health services for infants with CHD prior to surgery through the WeChat platform were useful in identifying the state of an infants’ condition as well as in identifying and relieving care pressure, anxiety and depression in the parents.

Platelet-Derived Growth Factor (PDGF) Stimulates Embryonic Cardiac Growth and Myofibrillogenesis

2001 ◽  
Vol 7 (S2) ◽  
pp. 1024-1025
Author(s):  
Stephen Haley ◽  
Robert L. Price ◽  
Tara A. Bullard ◽  
Louis Terracio
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Ductus Arteriosus ◽  
Receptor System ◽  
High Affinity ◽  
Septal Defects ◽  
Embryonic Origin ◽  
Underlying Causes

Congenital heart disease is a leading cause of death in children with about 40,000 babies born in America each year with congenital heart disease. Common problems include atrial septal defects, patent ductus arteriosus and ventricular septal defects. However, very little is known about the underlying causes of congenital heart disease or the embryonic origin of cardiac malformation. The goal of our recent research has been to examine the role that specific growth factors and their receptors play in the development of the contractile apparatus of the heart and the experiments reported here further define the role of PDGF-AA and the PDGF alpha-receptor (PDGFR-α) during early heart growth and morphogenesis.The PDGF ligand and receptor system consists of two well-characterized ligands, PDGF-A and B, and a third recently identified ligand, PDGF-C. The active forms of PDGFA and B exist as either AA or BB homodimers or an AB heterodimer. The PDGFR-α binds all of the dimers with high affinity while the PDGFR-β binds only the PDGF-BB homodimer with high affinity.

Congenital heart disease in 37,294 births in Tunisia: birth prevalence and mortality rate

2013 ◽  
Vol 24 (5) ◽  
pp. 866-871 ◽  
Author(s):  
Dorra Abid ◽  
Anis Elloumi ◽  
Leila Abid ◽  
Souad Mallek ◽  
Hajer Aloulou ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Septal Defect ◽  
Pulmonary Atresia ◽  
Coarctation Of The Aorta ◽  
Ventricular Septal Defects ◽  
Birth Prevalence ◽  
Septal Defects

AbstractAim: To investigate the previously unknown birth incidence, treatment, and mortality of children with congenital heart disease in Tunisia. Methods: We undertook a retrospective review of medical records of all patients who were born in 2010 and 2011, and were diagnosed in Sfax (Tunisia) with congenital heart defect. Results: Among 37,294 births, 255 children were detected to have congenital heart disease, yielding a birth incidence of 6.8 per 1000. The most frequently occurring conditions were ventricular septal defects (31%), ostium secundum atrial septal defects (12.9%), and pulmonary valve abnormalities (12%). Coarctation of the aorta, tetralogy of Fallot, univentricular physiology, pulmonary atresia with ventricular septal defect, and transposition of the great arteries were found in 4.3%, 6.2%, 3.4%, 2.7%, and 2.7%, respectively. During the follow-up of 1 year, 23% of the children died. About three-quarters of those deaths happened before surgery. Conclusion: The present study is in line with the general estimates in the world. It has revealed a high case of mortality among the patients awaiting corrective surgery. These children need more facilities.

Adult Congenital Heart Disease

2016 ◽  
Author(s):  
Patrizio Lancellotti ◽  
Bernard Cosyns
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Aortic Stenosis ◽  
Congenital Heart ◽  
Adult Congenital Heart Disease ◽  
Ductus Arteriosus ◽  
Haemodynamic Effect ◽  
Septal Defects ◽  
Adult Congenital

Echocardiography has a fundamental role in patients with adult congenital heart disease. This chapter identifies the role of echocardiography in atrial septal defects, ventricular septal defects, atrioventricular septal defects, patent ductus arteriosus, and persistent left superior vena cava. For each condition, the role of transthoracic and transoesophagael echocardiogram are shown alongside examples of main types and features and haemodynamic effect. Echocardiographic findings of LV outflow tract obstruction, supravalvular aortic stenosis, aortic stenosis, and aortic coarction are covered, as well as an examination of complex congenital lesions, including the tetralogy of Fallot and Ebstein’s anomaly of the tricuspid valve.

scholarly journals Clinical suspicion of congenital heart diseases during well-baby follow-up and echocardiographic correlation

2017 ◽  
Vol 4 (6) ◽  
pp. 2046
Author(s):  
K. M. Adhikari ◽  
Sandeep Dhingra
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Suspicion ◽  
Tertiary Care Center ◽  
Monthly Basis ◽  
Septal Defects

Background: Congenital heart disease (CHD), the most common cardiac malformation in the fetal and neonatal period, represents a heterogeneous group of defects with little known cause. Despite advances in detection and treatment, CHD accounts for 3% of all infant deaths and 46% of death from congenital malformations. CHD patients with minimum or no symptoms are frequently under diagnosed in areas with inadequate health services. The aim of this study was to investigate the role of clinical suspicion of congenital heart disease in babies who presented for well-baby follow-up against echocardiographic findings and to study the clinical spectrum of all the CHD that were diagnosed. Methods: The study involved analysis of data collected by the authors while working in a tertiary care center at Mumbai, India, during 2009 to 2010. All the babies born from April 2009 to August 2010 (17 months) and those who came for well-baby visits (with or without symptoms) were examined carefully for findings on cardiac examination including abnormalities of heart sound and presence of murmur on auscultation. Findings of the echocardiography were recorded for follow up and all the babies were followed up on at least three-monthly basis. Echocardiography was repeated on a quarterly basis in symptomatic babies and six-monthly basis in asymptomatic babies with small septal defects. All the babies on follow up were closely monitored clinically and on echocardiography for ascertaining the natural course of the observed defects. Results: A total of 1856 babies were born at the tertiary care center out of which 1688 were seen at the well-baby clinic. A total of 42 cases were referred for echocardiography on clinical suspicion of CHD and out of these 21 (50%) were positive for some form of CHD. Most common CHD diagnosed was atrial septal defect (ASD). There was no spontaneous closure of ventricular septal defects (VSD), though, 02 cases of ASD less than 3 mm closed during the during the follow up period.Conclusions: This study demonstrated that clinical experience is a valuable tool in early diagnosis of CHD, even if they are asymptomatic. Early echocardiography is justified to diagnose the cases so that appropriate follow-up and management decisions could be planned. Though majority of the cases were moderate to small ASD and VSD, there is a need to diagnose them early and follow them up till closure.

Congenital heart disease

2020 ◽  
pp. 743-790
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Ductus Arteriosus ◽  
Vena Cava ◽  
Ventricular Septal Defects ◽  
Segmental Analysis ◽  
Septal Defects ◽  
Atrial Septal Defects ◽  
Ventricular Outflow Obstruction

This chapter deals with the role of echocardiography in congenital heart disease. It covers views and findings, sequential segmental analysis, atrial septal defects and patent foramen ovale, atrial septal defects, ventricular septal defects, assessment of ventricular septal defects, left ventricular outflow and inflow obstruction, right ventricular outflow obstruction, transposition of the great arteries, persistent left superior vena cava, anomalous pulmonary drainage, tetralogy of Fallot, truncus arteriosus, double outlet right ventricle, single ventricle, surgical correction of congenital heart disease, Ebstein’s anomaly, patent ductus arteriosus, aortic coarctation, sinus of Valsalva aneurysm, Marfan syndrome, and congenital pericardial disease

Pulmonary Valve Endocarditis in a Corrected Tetralogy of Fallot

2021 ◽  
Author(s):  
Valentina Scheggi
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Tetralogy Of Fallot ◽  
Congenital Heart ◽  
Pulmonary Valve ◽  
Surgical Intervention ◽  
Pulmonary Valve Replacement ◽  
Late Complications ◽  
Tract Infections

Tetralogy of Fallot is the most common cyanotic congenital heart disease. In the last decades, the number of adults with surgically corrected defects is increasing and we have to face with late complications. Echocardiography has a central role in the early diagnosis of these conditions. We report the case of a 31-year-old man, treated during childhood with surgical repair of the ventricular septal defect, ventricular right outflow plasty, and pulmonary valve commissurotomy. At the age of 30 years, the patient underwent a second surgical intervention (aortic root replacement and pulmonary bioprosthesis implantation). He was also affected by urethral stenosis and complained of relapsing urinary tract infections. At the admission to our department, he reported remittent fever ensued one month before. We performed a third surgical intervention (aortic and pulmonary valve replacement) after diagnosing Steptococcusagalactiae endocarditis involving the pulmonary prosthesis and the native aortic valve. In conclusion, echocardiographic follow-up and prevention of infection are the mainstays to improve the outcome of corrected congenital heart disease.

scholarly journals Initial use of endothelial progenitor cells capturing stents in paediatric congenital heart disease

2013 ◽  
Vol 24 (5) ◽  
pp. 900-904 ◽  
Author(s):  
Nuno Cabanelas ◽  
José D. F. Martins ◽  
Fátima Pinto
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Stent Implantation ◽  
Congenital Heart ◽  
Ductus Arteriosus ◽  
Neointimal Hyperplasia ◽  
Complex Congenital Heart Disease ◽  
Endothelial Progenitor ◽  
Transcutaneous Oxygen

AbstractIntroductionStenosis, mediated by neointimal hyperplasia and thrombosis, is a major limiting factor in successful stent implantation. The introduction of a stent, coated in its endoluminal surface by antihuman CD34 antibodies with endothelial progenitor cell-capturing properties, opens the possibility of promoting a rapid and normal functioning coverage by endothelium and thus avoids both an excessive cell proliferation within stent and the need for long-term dual antiplatelet therapy. These stents, developed for adult coronary artery disease, have not yet been implanted in children or in those with congenital heart disease.Objective and methodsIn this paper, we describe the implantation of Genous®stents in three children with cyanotic congenital heart disease and obstructed systemic-to-pulmonary shunts. We describe the use of this stent and address its potential feasibility in paediatric congenital heart disease.ResultsTo maintain the patency of two modified Blalock–Taussig shunts and one ductus arteriosus, four Genous®stents were implanted in three infants with cyanotic heart disease. All procedures were immediately successful, with resolution of stenosis and improvement in transcutaneous oxygen saturation from 66% ± 3.6% to 92% ± 2.6%. In the follow-up, one stent had no occlusion; however, the remaining two had partial occlusion after 5 and 5.5 months, which were successfully managed with balloon dilatation preceding elective definitive surgical correction.ConclusionIn our preliminary experience, we demonstrated that Genous®stent implantation was feasible in infants with complex congenital heart disease. Additional studies with larger samples and longer follow-up are required to confirm the potential benefits of this technology in this clinical setting.

scholarly journals Study of congenital heart disease in neonates: clinical profile, diagnosis, immediate outcome and short-term follow-up

2018 ◽  
Vol 5 (4) ◽  
pp. 1304
Author(s):  
Vinod Kumar Ravilala ◽  
Sreenivas Kotla ◽  
Radhakishan T. ◽  
Ranjeet Malava
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Early Recognition ◽  
Structural Heart Disease ◽  
Short Term ◽  
Transposition Of Great Arteries ◽  
Presenting Symptoms ◽  
Tract Infections

Background: Congenital heart disease (CHD) occurs in approximately 0.8% of live births. Early recognition of CHD is important for appropriate management and decision making regarding referral. The purpose of this study was to document the common presenting symptoms and signs in the neonates with CHD, definitive diagnosis and short-term follow-up for six months.Methods: Sixty full term neonates with suspected CHD admitted in neonatal intensive care unit (NICU) at Niloufer Hospital, Hyderabad during the period December 2016 to May 2017 were included in the study.Results: Of the 60 neonates, most common age of presentation was for first week (45%, n = 27). Of the 60 neonates, 32 (54%) were males and 28 (46%) were females. The commonest presentation was hurried respiration (68%), followed by feeding problem (63%) and only eight neonates were asymptomatic with clinically significant murmur. 40% (n = 24) of the babies were born of consanguineous marriage. 72% (n = 43) of babies presented with murmur and 6 babies had extra-cardiac manifestations. Babies with acyanotic CHD were 38 (63%) of which ventricular septal defect (VSD) was the commonest. Cyanotic CHD were 22 (37%) of which transposition of great arteries (TGA) was the commonest. 25 babies (42%) expired during neonatal period. Of the remaining babies during follow-up, 29 % of babies thrived well, 35% presented with repeated respiratory tract infections, 21% with failure to thrive and 15% with congestive heart failure (CHF).Conclusions: Neonates with CHD have a unique presentation and they carry poor outcome unless diagnosed early and managed appropriately. Babies presenting with multiple anomalies should be screened for any underlying structural heart disease.

Prevalence of congenital heart disease among Palestinian children born in the Gaza Strip

2013 ◽  
Vol 24 (5) ◽  
pp. 905-909 ◽  
Author(s):  
Mahmoud Zaqout ◽  
Emad Said Aslem ◽  
Forijat Sadeldin Oweida ◽  
Daniel De Wolf
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Medical Center ◽  
Gaza Strip ◽  
Ductus Arteriosus ◽  
Actuarial Survival ◽  
Live Births ◽  
Septal Defects ◽  
The Gaza Strip

AbstractObjectiveThis study was designed to estimate the birth prevalence of children with congenital heart disease born in the Gaza Strip during 2010 and to compare these with estimates from elsewhere.MethodsWe reviewed the medical records of all children born in 2010 who were diagnosed, treated, and/or followed up in the four paediatric cardiology clinics in the Gaza Strip. Data were also obtained from El Makassed Hospital in East Jerusalem and from the Schneider Hospital, Wolfson Medical Center, and Tel HaShomer Hospital in Israel, where we had referred some of our patients for percutaneous or surgical treatment.ResultsA total of 598 children with congenital heart disease were detected among the 59,757 children born alive in the Gaza Strip during 2010, yielding a birth incidence of 10 per 1000 live births. The most frequently occurring conditions were ventricular septal defects (28%), ostium secundum atrial septal defects (17%), patent ductus arteriosus (8.5%), and pulmonary valve abnormalities (8%). In this study, 7% of the children died. The actuarial survival at 6 months and 1 year of age was 94% and 93%, respectively, and remained stable over 18 months of follow-up.ConclusionThe birth incidence of congenital heart disease in the Gaza Strip in 2010 (10 per 1000) is higher than most estimates in Western Europe (8.2 per 1000 live births) and North America (6.9 per 1000 live births) but is similar to estimates from other parts of Asia (9.3 per 1000 live births).

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