Spectrophotometric Determination of Decamethrin and Its Residues in Insecticidal Formulations and in Water

1994 ◽  
Vol 77 (3) ◽  
pp. 748-751 ◽  
Author(s):  
R V Prabhakara Raju ◽  
R Raghava Naidu
Keyword(s):  
Spectrophotometric Determination ◽  
Hydrolysis Product ◽  
Spectrophotometric Methods ◽  
Alkaline Conditions ◽  
The Relationship ◽  
Hydrolysis Of

Abstract Three spectrophotometric methods were developed for the microdetermination of decamethrin in insecticidal formulations and in water. The methods are based on the hydrolysis of decamethrin with methanolic KOH to 3-phenoxybenzaldehyde; condensation of the hydrolysis product with 2,4- dinitrophenylhydrazine (2,4-DNPH), 4-nitrophenylhydrazine (4-NPH), or 2,4,6-trinitrophenylhydrazine (2,4,6-TNPH) under alkaline conditions; and measurement of the condensates at the absorption maxima of 444,535, and 480 nm, respectively. The relationship between absorbance and concentration was linear in the ranges of 0.1–5.0 μg/mL, 0.5–7.0 μg/mL and 0.1–5.5 μg/mL for 2,4-DNPH, 4-NPH, and 2,4,6-TNPH, respectively. The methods are sufficiently sensitive and can be used to detect decamethrin at concentrations as low as 0.1 μg/mL.

DC Polarographic and Spectrophotometric Determination of Ampicillin Capsules

1980 ◽  
Vol 63 (5) ◽  
pp. 1049-1051
Author(s):  
Juan A Squella ◽  
Luis J Nunez-Vergara ◽  
Maximo Aros
Keyword(s):  
Absorption Band ◽  
Spectrophotometric Determination ◽  
Degradation Product ◽  
Uv Absorption ◽  
Acidic Hydrolysis ◽  
Average Recovery ◽  
Polarographic Wave ◽  
Spectrophotometric Methods ◽  
Hydrolysis Of

Abstract Polarographic and spectrophotometric methods are proposed for the determination of ampicillin in capsules. Acidic hydrolysis of ampicillin with 1% HCHO in 0.3N HCl yields a degradation product identified as 2-hydroxy-3-phenyl-6-methylpyrazine. This compound has a well defined UV absorption band at 380 nm and a polarographic wave at –0.55 V vs SCE, which can be used for analytical purposes. Individual capsule assays, composite assays, and recovery studies are described. The average recovery values and standard deviations (SD) for UV and polarographic determinations were 99.20% (SD 0.95) and 100.85% (SD 1.09), respectively

Spectrophotometric Determination of Carbaryl in Grains

1982 ◽  
Vol 65 (1) ◽  
pp. 32-34
Author(s):  
Kalapanda M Appaiah ◽  
Rasamsetti Ramakrishna ◽  
Kadari R Subbarao ◽  
Omprakash Kapur
Keyword(s):  
Spectrophotometric Determination ◽  
Absorption Maximum ◽  
Potassium Hydroxide ◽  
Oxidizing Agent ◽  
Spectrophotometric Measurement ◽  
The Relationship ◽  
Hydrolysis Of

Abstract A method has been developed for determining carbaryl (1-naphthyl N-methyl carbamate) in grains, based on hydrolysis of carbaryl with methanolic potassium hydroxide to 1-naphthol, reaction with 4-aminophenazone in the presence of alkaline oxidizing agent, and spectrophotometric measurement at the absorption maximum at 475 nm. The relationship between absorbance and concentration is linear in the range of 0.5-20 μg/mL. The method can be applied to levels as low as 0.3 ppm carbaryl in grains.

scholarly journals Spectrophotometric Determination of Adefovir Dipivoxil in bulk and Pharmaceutical Formulation

2008 ◽  
Vol 5 (4) ◽  
pp. 713-717 ◽  
Author(s):  
Zaheer Ahmed ◽  
Y. N. Manohara ◽  
K. P. Channabasawaraj ◽  
Manish Majumdar
Keyword(s):  
Acid Hydrolysis ◽  
Spectrophotometric Determination ◽  
Sodium Salt ◽  
Adefovir Dipivoxil ◽  
Pharmaceutical Preparations ◽  
Pharmaceutical Formulations ◽  
Spectrophotometric Methods ◽  
Acid Sodium Salt ◽  
Alkaline Conditions

Two selective and sensitive spectrophotometric methods have been developed for the estimation of adefovir dipivoxil in bulk and pharmaceutical preparations. Adefovir dipivoxil was subjected to acid hydrolysis and the hydrolysed product used for the estimation. The methods are based on the reaction with 3-methyl-2-benzothiazolinone hydrazone in the presence of ferric chloride, to form a colored species with absorption maxima at 627 nm. The second method is based on the reaction of drug with 1,2 naphthaquinone -4-sulphonic acid sodium salt, under alkaline conditions which absorbs maximally at 454 nm. Beers law is obeyed in the concentration range of 5-25 µg/mL and 2-10 µg/mL respectively. These methods were extended to pharmaceutical formulations and there was no interference from excepients and diluents. The analytical parameters were evaluated.

Benzyl ethers of methyl α-D-glucopyranoside

1980 ◽  
Vol 45 (7) ◽  
pp. 1959-1963 ◽  
Author(s):  
Dušan Joniak ◽  
Božena Košíková ◽  
Ludmila Kosáková
Keyword(s):  
Kinetic Study ◽  
Spectrophotometric Determination ◽  
Reductive Cleavage ◽  
Ether Bond ◽  
Benzyl Ethers ◽  
Acid Catalyzed ◽  
Model Substances ◽  
Hydrolysis Of

Methyl 4-O-(3-methoxy-4-hydroxybenzyl) and methyl 4-O-(3,5-dimethoxy-4-hydroxybenzyl)-α-D-glucopyranoside and their 6-O-isomers were prepared as model substances for the ether lignin-saccharide bond by reductive cleavage of corresponding 4,6-O-benzylidene derivatives. Kinetic study of acid-catalyzed hydrolysis of the compounds prepared was carried out by spectrophotometric determination of the benzyl alcoholic groups set free, after their reaction with quinonemonochloroimide, and it showed the low stability of the p-hydroxybenzyl ether bond.

Determination of Carbaryl Residues in Honey Bees

1965 ◽  
Vol 48 (4) ◽  
pp. 771-774
Author(s):  
D P Johnson ◽  
H A Stansbury
Keyword(s):  
Aqueous Solution ◽  
Acetic Acid ◽  
Quantitative Determination ◽  
Honey Bees ◽  
Methylene Chloride ◽  
Hydrolysis Product ◽  
Separate Analysis ◽  
Yellow Substance ◽  
Hydrolysis Of

Abstract A method has been developed for detecting residues of carbaryl (1-naphthyl methylcarbamate) as well as its hydrolysis product, 1-naphthol, in dead bees. The method is based on extraction of the bees with benzene, followed by a cleanup involving liquid partitioning and chromatography on Florisil. The quantitative determination involves hydrolysis of carbaryl to 1-naphthol and coupling of the latter with p-nitrobenzenediazonium fluoborate in acetic acid to form a yellow substance. For separate analysis, free 1-naphthol is separated from methylene chloride into a basic aqueous solution. The sensitivity of the method is about 0.1 ppm; recoveries averaged 85.6 ± 6.6% for 1- naphthol and 83.8 ± 2.7% for carbaryl.

Spectrophotometric Determination of Methomyl Residues in Selected Vegetables, Crains, and Soil

1977 ◽  
Vol 60 (5) ◽  
pp. 1093-1096
Author(s):  
Jois R Rangaswamy ◽  
Shimoga R Prakash ◽  
Yadathora N Vijayashankar
Keyword(s):  
Spectrophotometric Determination ◽  
Absorption Maximum ◽  
Acid Treatment ◽  
Sulfanilic Acid ◽  
Benzenesulfonic Acid ◽  
The Relationship

Abstract Methomyl (S-methyl-N-[(methylcarbamoyl) oxy] thioacetimidate) is converted to oxime and hydroxylamine by alkali and acid treatment, respectively. Hydroxylamine is oxidized with iodine in the presence of sulfanilic acid to yield p-diazoniumbenzenesulfonic acid which is coupled with α-naphthylamine to form a crimson p-benzenesulfonic acid-azo-α-naphthylamine with an absorption maximum at 520 nm. The relationship between absorbance and concentration of methomyl is linear in the range 0.5–10 μg. The method is sensitive and specific; 0.625 ppm methomyl can be determined in a 40 g sample of selected vegetables, grains, and soil.

scholarly journals Use of N, N-diethyl-p-phenylenediamine sulphate for the spectrophotometric determination of some phenolic and amine drugs

2010 ◽  
Vol 60 (2) ◽  
pp. 217-227 ◽  
Author(s):  
Padmarajaiah Nagaraja ◽  
Ashwinee Shrestha ◽  
Anantharaman Shivakumar ◽  
Avinash Gowda
Keyword(s):  
Spectrophotometric Determination ◽  
Correlation Coefficients ◽  
Dosage Forms ◽  
Pharmaceutical Dosage Forms ◽  
Variable Parameters ◽  
Spectrophotometric Methods ◽  
Linear Relationships ◽  
Colored Product ◽  
And Performance

Use ofN, N-diethyl-p-phenylenediamine sulphate for the spectrophotometric determination of some phenolic and amine drugsSpectrophotometric methods are proposed for the determination of drugs containing a phenol group [salbutamol sulphate (SLB), ritodrine hydrochloride (RTD), isoxsuprine hydrochloride (IXP)] and drugs containing an aromatic amine group [dapsone hydrochloride (DAP), sulfamethoxazole (SFM), and sulfadiazine (SFD)] in pharmaceutical dosage forms. The methods are based on coupling ofN, N-diethyl-p-phenylenediamine sulphate with the drugs in the presence of KIO4to give a green colored product (λmaxat 670 nm) and a red colored product (λmaxat 550 nm), respectively. Linear relationships with good correlation coefficients (0.9986-0.9996) were found between absorbance and the corresponding concentration of drugs in the range 1-7, 2-22, 1-17, 1.5-12, 2-25, and 2-21 μg mL-1for SLB, RTD, IXP, DAP, SFM and SFD, respectively. Variable parameters such as temperature, reaction time and concentration of the reactants have been analyzed and optimized. The RSD of intra-day and inter-day studies was in the range of 0.2-1.0 and 0.4-1.0%, respectively. No interference was observed from common pharmaceutical adjuvants. The reliability and performance of the proposed methods was validated statistically; the percentage recovery ranged from 99.5 ± 0.1 to 99.9 ± 0.3%. Limits of detection were 0.14, 0.21, 0.51, 0.44, 0.33 and 0.37 μg mL-1for SLB, RTD, IXP, DAP, SFM, and SFD, respectively.

Simultaneous Spectrophotometric Determination of Nifuroxime and Furazolidone in Pharmaceutical Preparations

1980 ◽  
Vol 63 (5) ◽  
pp. 992-995
Author(s):  
Laila Elsayed ◽  
Sayed M Hassan ◽  
Khadiga M Kelani ◽  
Hamed M El-Fatatry
Keyword(s):  
Simultaneous Determination ◽  
Spectrophotometric Determination ◽  
Pharmaceutical Preparations ◽  
Spectrophotometric Methods ◽  
First Derivative ◽  
Separation Step ◽  
Preliminary Separation

Abstract Two spectrophotometric methods have been developed for the simultaneous determination of nifuroxime and furazolidone in their pharmaceutical preparations. No preliminary separation step is required in either method. The first, a modified Vierordt method, gives accurate and reproducible results for both drugs. Mean percent recoveries for nifuroxime and furazolidone were 99.50 ±1.59 and 100.20 ±1.16 (P = 0.05), respectively. This method also gives accurate and reproducible results for the determination of nifuroxime and furazolidone in their pharmaceutical preparations: Tricofuran vaginal suppositories and powder. The second method, which involves the use of the first-derivative curves, gives unreliable results; the reasons for these are discussed.

First Derivative Spectrophotometric Determination of Anhydrotetracyclines in Tetracyclines

1988 ◽  
Vol 71 (4) ◽  
pp. 768-772 ◽  
Author(s):  
Abdel-Aziz M Wahbi ◽  
Hamad A Al-Khamees ◽  
Ahmad M A Yousef
Keyword(s):  
Rapid Method ◽  
Spectrophotometric Determination ◽  
Absorption Curve ◽  
British Pharmacopoeia ◽  
Spectrophotometric Methods ◽  
First Derivative ◽  
Tetracycline Hcl

Abstract A rapid method is presented for detection and determination of anhydrotetracycline- HCl (ATC-HC1) and 4-epianhydrotetracycline-HCl (4-EATC-HCl) in tetracycline-HCl (TC-HCl). The method determines the 2 compounds as a sum, not individually. The first derivative absorption curve has a trough (D1) at 460 nm which is linearly related to concentration (1-10 mg/mL). ATC-HC1 + 4-EATC-HCl content was determined in TC-HCl powder and capsules by the D1 and the compensation D1 spectrophotometric methods. The results were compared with those obtained using U.S. Pharmacopeia and British Pharmacopoeia methods

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