PSXVI-17 Estimation of inbreeding in local sheep breeds of west Asian and central Asian origin based on high-density SNP-genotypes

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 222-223
Author(s):  
Tatiana E Deniskova ◽  
Alexandra S Abdelmanova ◽  
Arsen V Dotsev ◽  
Eugenia Lushihina ◽  
Asankadyr Zhunushev ◽  
...  

Abstract Maintaining high levels of genetic diversity is a key factor of successful breeding of resilient, resistant to diseases and productive sheep. Prevention of inbreeding is of special importance in the mountainous hard-to-get habitats where gene flow is limited or absent. An assessment of inbreeding coefficients based only on pedigree information is not always correct. In addition, pedigree information is often missing for flocks of native sheep. In this regard, we performed a genomic assessment of inbreeding in 15 local sheep breeds inhabiting severe environments of Russia and neighboring Asian countries based on estimations of standardized multilocus heterozygosity (sMLH) and runs of homozygosity [F(ROH)]. For this study, we used SNP genotypes of twelve Russian local breeds (n = 316) and three Kyrgyz local breeds (n = 68), which were generated using Ovine Infinium® HD SNP BeadChip (Illumina, CA, USA). The sMLH values were calculated using R package inbreedR and visualized in R package ggplot2. The F(ROH) values were calculated using the R package detectRUNS by applying the consecutive runs method. Mean sMLH values were varied from 0.962 ± 0.006 in the Andean breed to 1.031 ± 0.002 in the Buryat breed and averaged to 1.001± 0.004. The least mean F(ROH) value was detected in the Mongolian breed (0.0043 ± 0.0009) while the greatest ones were observed in the Alai and Andean breeds (0.0364 ± 0.0049 and 0.0357 ± 0.0061, respectively). The strong negative correlations between sMLH and F(ROH) were detected for all of studied breeds (r2 = –0.8496, CI = –0.8752… –0.8192). The obtained data is relevant for control of inbreeding level in the populations and for future sustainable management of native fat-tailed sheep breeds. The study was funded by RSF No. 19-16-00070.

2018 ◽  
Vol 63 (No. 12) ◽  
pp. 507-517 ◽  
Author(s):  
E. Skotarczak ◽  
P. Ćwiertnia ◽  
T. Szwaczkowski

An effective realization of breeding programs in zoos is strongly determined by completeness of animal pedigree information. The knowledge of pedigree structure allows to maintain optimal genetic variability of a given population. The aim of this study was to estimate the parameters describing the pedigree structure of American bison housed in zoos in the context of further management of the population. Finally, 4269 American bison were analysed (1883 males, 2217 females, and 169 with unknown sex). The registered animals were born between years 1874 and 2013. The following pedigree parameters were estimated: number of fully traced generations, number of complete generations equivalent, index of pedigree completeness, individual inbreeding coefficients, increase of inbreeding for each individual, effective population size, and genetic diversity. The maximum number of fully traced generations was 3 (the mean value is 0.693). The mean inbreeding coefficient for the population studied was 3.26%, whereas individual increase in inbreeding ranged from 0 to 25.12%. Although the pedigree parameters (including the inbreeding level) in the American bison obtained in the present study seem to be acceptable (from the perspective of other wild animal populations), they can be over/underestimated due to incomplete pedigree.


Author(s):  
Mehri Vokhidova

This article will cover a wide range of key issues in the economies of the Central Asian countries, the extent of their development and opportunities for trade and economic relations.The aim of the study is to analyze trends and opportunities for improving trade and economic relations between the countries of Central Asia.The objectives of the study are:- to analyze the volume and tendency of GDP of Central Asian countries for 2000-2018;- analysis of the GDP per capita in the countries of Central Asia;- Comparative analysis of export and import volume, structure of export and import of Central Asian countries;- to study the relations of Central Asian countries with international organizations and to find mutual interests;- Identification of political, economic and social problems that impede the development of trade and economic relations in Central Asian countries.The results are as follows:- the main focus of improving trade and economic relations between the countries of Central Asia on the border of two or more countries is the Free Economic Zone;- Diversification of the economies of Uzbekistan and Kazakhstan in relation to other countries in the region can be a key factor in the development of trade and economic relations;- Expanding the role of regional organizations and integration in improving trade and economic relations between Central Asian countries.- The practical result of the establishment of transboundary free economic zones in Central Asia.


2018 ◽  
Vol 51 (2) ◽  
pp. 161-171
Author(s):  
B.Zh Somzhurek ◽  
A.M. Yessengaliyeva ◽  
Zh.M. Medeubayeva ◽  
B.K. Makangali

This paper aims to analyze the politico-military cooperation among the Central Asian countries viewed as a key factor in ensuring the regional security. Today, the geopolitical tension in the surrounding regions, the worsening situation in Afghanistan, as well as intraregional socio-economic problems directly affect the security situation in Central Asia. In this regard, the question arises as to how well the Central Asian states are able to meet these challenges. The analysis of the situation in the region in the 1990s and at the beginning of the new century shows that attempts have been made to establish a regional security system based on military cooperation among Kazakhstan, Uzbekistan, Kyrgyzstan and Tajikistan. However, unregulated interstate relations in Central Asia, the lack of political will to cooperate with leaders of neighboring countries and the combination of external and internal threats have contributed to the creation of a regional security system based on the multilateral structures with the involvement of external actors.


Author(s):  
Tokhir S. Kalandarov

Today there are hundreds of papers published on the problem of labor migration from Central Asian countries, its political, social and economic aspects, as well as on the problem of integration and adaptation of migrants in the Russian society. However, the topic of migrant poetry is still poorly studied in Russia. At least there is no such research on Tajik labor migrants. The genres of Tajik migrant poetry vary significantly and include such forms as love poems, political songs, songs about migration hardships, religious poems. This paper is based on the results of monitoring social networks «Odnoklassniki», «Facebook», as well as on the results of personal communication and interviews with poets. In the paper we use the poems of three authors written in Tajik, Russian and Shugnani languages. The semantic translation from Tajik and Shugnani was done by the author of this paper


2020 ◽  
pp. 72-79
Author(s):  
S. Gavrilova

For several decades, the European Union has been steadily increasing its presence in Central Asian countries. The EU's interests in the region are due to a number of reasons, including the desire to expand its influence in the Central Asian countries, the high importance of the region as a transit corridor between Europe and China, the prospects for economic cooperation, and the importance of the region's energy potential. In May 2019 The European Union has presented a new Strategy for Central Asia, designed to intensify cooperation in a number of areas of interaction. The new strategy is aimed at both implementing these interests and expanding cooperation in a number of other areas.


2021 ◽  
Vol 22 (2) ◽  
pp. 110-121
Author(s):  
Karlygash MUKHTAROVA ◽  
Yermukhambet KONUSPAYEV ◽  
Klara MAKASHEVA ◽  
Karim SHAKIROV

Improving the forms and mechanisms of regional economic integration, deepening the mutual understanding on the formation of an economically and politically secure integrated space, expanding trade and economic relations, elaborating joint actions to maintain regional peace and stability, creating a single information space are among the key areas that have become the basis of cooperation among the Central Asian region (CAR) states. The authors reveal the positive aspects of cooperation among the CAR countries—Kazakhstan, Kyrgyzstan, Uzbekistan, Turkmenistan, and Tajikistan. First and foremost, these include common historical roots, linguistic and cultural similarity, convenient geographical location and established economic ties, which allow the states of Central Asia (CA) to establish a deeper and more active understanding of each other, to solve economic and political problems related to finding and realizing domestic investment potential and expanding regional trade and economic ties. The joint establishment of international transport corridors and infrastructure will help reduce the transport costs for Central Asian countries that supply export products to external markets, which is an important area of ​​cooperation in Central Asia. In addition, the economic problems that exist among the regional countries largely determine the nature of relations between them. Future solution of problems determines the subsequent viability of the Central Asian Regional Economic Cooperation (CAREC) and the regional development prospects. Based on the use of economic research tools, the authors examine the problems caused by the COVID-19 pandemic and their impact on the state of trade and economic relations between the regional states. Post-crisis plans for economic recovery in the Central Asian countries will be developed and implemented in the context of the need to solve the present-day problems associated with the gradual lifting of quarantine measures. In this regard, the quickest possible transition of economies to an upward growth trajectory should launch the expansion of trade and economic cooperation and ties among the Central Asian countries. The authors emphasize the fact that another important problem within CAREC is the fact that CAR economies are dominated by raw materials, which does not solve the problems of reducing social inequality and improving the welfare of the regional population. For this reason, Kazakhstan, like other Central Asian countries, is currently in search of a new economic model. The transformation is crucial because the country needs to overcome its excessive long-term dependence on the export of oil and raw materials. The new economic model should be focused on further industrialization and diversification of the economy, on the search for new innovative approaches and development strategies.


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