Musculoskeletal Imaging Volume 2

This volume meets the needs of radiology residents to become adept at interpreting musculoskeletal (MSK) imaging studies. It does so by presenting core knowledge and fundamentals that must be learned to accurately and effectively interpret MSK studies by the trainee and non-specialist. The goal is to impart to residents, as well as to refresh for practitioners, essential facts in a concise and readable format so the reader becomes conversant with all imaging modalities used and the essentials of interpretation and technique. Other resources are at too high a level for the resident in training or contain far more information than a resident can easily assimilate during a rotation. The book is part of the Rotations in Radiology series for residents, which defines and encapsulates core knowledge for areas within Radiology, offering a guided, structured approach to imaging diagnosis. It contains sections on 10 key topics in MSK radiology: trauma; arthritis; tumors and tumor-like conditions; metabolic, hematopoietic, endocrine, and deposition diseases; infectious diseases; arthrography; internal derangements of the joints; congenital diseases; and ultrasound. Each section begins with an overview chapter, orienting the reader to the specific concerns and issues related to imaging that anatomic region or category of problem. Each clinical problem or diagnosis is concisely covered to provide a targeted discussion and highlight salient points. For each topic, concise chunks of text will review: definition; clinical features; anatomy and physiology; how to appraoch the image; what not to miss; differential diagnosis; common variants if pertinent; clinical issues; key points; high yield references.

This volume meets the needs of radiology residents to become adept at interpreting musculoskeletal (MSK) imaging studies. It does so by presenting core knowledge and fundamentals that must be learned to accurately and effectively interpret MSK studies by the trainee and non-specialist. The goal is to impart to residents, as well as to refresh for practitioners, essential facts in a concise and readable format so the reader becomes conversant with all imaging modalities used and the essentials of interpretation and technique. Other resources are at too high a level for the resident in training or contain far more information than a resident can easily assimilate during a rotation. The book is part of the Rotations in Radiology series for residents, which defines and encapsulates core knowledge for areas within Radiology, offering a guided, structured approach to imaging diagnosis. It contains sections on 10 key topics in MSK radiology: trauma; arthritis; tumors and tumor-like conditions; metabolic, hematopoietic, endocrine, and deposition diseases; infectious diseases; arthrography; internal derangements of the joints; congenital diseases; and ultrasound. Each section begins with an overview chapter, orienting the reader to the specific concerns and issues related to imaging that anatomic region or category of problem. Each clinical problem or diagnosis is concisely covered to provide a targeted discussion and highlight salient points. For each topic, concise chunks of text will review: definition; clinical features; anatomy and physiology; how to appraoch the image; what not to miss; differential diagnosis; common variants if pertinent; clinical issues; key points; high yield references.


Author(s):  
Aileen Becker ◽  
Dominique Böttcher ◽  
Werner Katzer ◽  
Karsten Siems ◽  
Lutz Müller-Kuhrt ◽  
...  

Abstract Raspberry ketone is a widely used flavor compound in food and cosmetic industry. Several processes for its biocatalytic production have already been described, but either with the use of genetically modified organisms (GMOs) or incomplete conversion of the variety of precursors that are available in nature. Such natural precursors are rhododendrol glycosides with different proportions of (R)- and (S)-rhododendrol depending on the origin. After hydrolysis of these rhododendrol glycosides, the formed rhododendrol enantiomers have to be oxidized to obtain the final product raspberry ketone. To be able to achieve a high conversion with different starting material, we assembled an alcohol dehydrogenase toolbox that can be accessed depending on the optical purity of the intermediate rhododendrol. This is demonstrated by converting racemic rhododendrol using a combination of (R)- and (S)-selective alcohol dehydrogenases together with a universal cofactor recycling system. Furthermore, we conducted a biocatalytic cascade reaction starting from naturally derived rhododendrol glycosides by the use of a glucosidase and an alcohol dehydrogenase to produce raspberry ketone in high yield. Key points • LB-ADH, LK-ADH and LS-ADH oxidize (R)-rhododendrol • RR-ADH and ADH1E oxidize (S)-rhododendrol • Raspberry ketone production via glucosidase and alcohol dehydrogenases from a toolbox Graphical abstract


2019 ◽  
Author(s):  
Martin Bilek ◽  
◽  
Katerina Chroustova ◽  
Jiri Rychtera ◽  
Veronika Machkova ◽  
...  

The research was focused on the teacher’s opinions about the key and critical points of the lower secondary chemistry curriculum in the Czech Republic. Through the interviews with 40 chemistry teachers from four Czech regions was gained information about what teachers named as critical topics and what as key topics in early chemistry school contents. Some problems were identified mainly with cognition overload of learners and the necessity to realize stronger connections to everyday life and forming science literacy. Keywords: chemistry teachers’ opinions, early chemistry education, key points of the curriculum, critical points of the curriculum.


2019 ◽  
Vol 119 (1) ◽  
pp. 2-17 ◽  
Author(s):  
Cherylea J. Browne

Purpose Introductory anatomy and physiology provide a core knowledge base to students within clinical health science courses. Increased student numbers, as well as reduced access to laboratory-based cadaveric resources, have created a need for enhanced learning approaches to support learning. The streamlining of courses has also resulted in the need to effectively engage course sub-groups within large units. The purpose of this paper is to utilize the eLearning activities to investigate engagement and satisfaction levels within students undertaking an anatomy and physiology unit. Design/methodology/approach A total of 19 formative quizzes were made available to students. Online practical anatomy laboratories covered anatomical content, and physiology quizzes covered physiological content. Student engagement was compared using frequency analysis across students studying varying courses. Satisfaction was determined by analyzing student’s feedback using frequency analysis. Findings Students accessed the learning activities 29,898 times over semester, with the peak access (37 percent) prior to the closed book exams. The resources were utilized primarily as an exam preparation tool rather than consistently throughout semester. Out of the various courses, the Paramedicine, Physiotherapy and Podiatry students were the most engaged, with the highest percent of “engaged/highly engaged” students. Students from various courses shared very similar views of the perceived benefit of the eLearning activities. Practical implications These results indicated a difference in engagement levels between the students of various course sub-groups, and therefore suggests that the development of course-specific eLearning activities is necessary in large, streamlined units to achieve a more focused approach to support students’ learning, engagement and success, so that positive and beneficial learning experiences are ensured for all students. Originality/value These results suggest that in the future, development of eLearning activities is necessary to achieve a more focused approach to support students’ learning, engagement and success, so that positive and beneficial learning experiences are ensured for all.


2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Hossein Motedayyen ◽  
Nafiseh Esmaeil ◽  
Nader Tajik ◽  
Fahimeh Khadem ◽  
Somayeh Ghotloo ◽  
...  

Author(s):  
M. Gabriel Hillegass ◽  
Anthony A. Tucker ◽  
Antonio Quidgley-Nevares

This chapter on musculoskeletal pain is composed of a question-and-answer bank that encompasses the breadth of the fund of knowledge required for the evaluation and management of various chronic musculoskeletal pain syndromes. Not only do probing questions with concise and informative answer explanations challenge the reader’s knowledge base but also references for further reading and mastery of the subject are provided. Topics covered include epidemiology, disability, rehabilitation, anatomy and physiology (including neurophysiology and mediators of inflammation), and the musculoskeletal exam. The pathophysiology, diagnosis, and management of musculoskeletal pain conditions such as common orthopedic and occupational injuries, osteoarthritis, chronic tissue pain states, and various autoimmune diseases (e.g., rheumatoid arthritis) are also expertly reviewed. These high-yield questions correspond to the musculoskeletal pain section of the American Board of Medical Specialties Pain Medicine Content Outline.


2005 ◽  
Author(s):  
Agustin Legido ◽  
Joseph H. Piatt

This all-new clinical resource equips primary caregivers to take a lead role in the diagnosis, evaluation, and management of diverse pediatric neurologic and neurosurgical conditions. For practice-focused guidance with a coordinated dual perspective you won't find anywhere else. The developers/editors are a pediatric neurologist and a pediatric neurosurgeon at the forefront of their fields. Key topics are considered from neurologic and neurosurgical viewpoints. Purpose-built for efficient clinical problem solving; clear, concise overviews of a broad range of common conditions; evidence-based discussion of each condition's course, pathogenesis, and etiology; expert management recommendations; advice on when to treat vs when to refer; and the practical implications of recent research. Contents include neonatal disorders, encephalopathies, traumatic brain injury, cerebrovascular disorders, febrile seizures, epilepsy, headaches, brain tumors, spina bifida and neurogenic bladder dysfunction, movement disorders, neuromuscular disorders, and neurocutaneous disorders.


2021 ◽  
Vol 105 (7) ◽  
pp. 2967-2977
Author(s):  
Rosa Margesin ◽  
Georg Volgger ◽  
Andreas O. Wagner ◽  
Dechao Zhang ◽  
Caroline Poyntner

Abstract Lignin bio-valorization is an emerging field of applied biotechnology and has not yet been studied at low temperatures. Paraburkholderia aromaticivorans AR20-38 was examined for its potential to degrade six selected lignin monomers (syringic acid, p-coumaric acid, 4-hydroxybenzoic acid, ferulic acid, vanillic acid, benzoic acid) from different upper funneling aromatic pathways. The strain degraded four of these compounds at 10°C, 20°C, and 30°C; syringic acid and vanillic acid were not utilized as sole carbon source. The degradation of 5 mM and 10 mM ferulic acid was accompanied by the stable accumulation of high amounts of the value-added product vanillic acid (85–89% molar yield; 760 and 1540 mg l−1, respectively) over the whole temperature range tested. The presence of essential genes required for reactions in the upper funneling pathways was confirmed in the genome. This is the first report on biodegradation of lignin monomers and the stable vanillic acid production at low and moderate temperatures by P. aromaticivorans. Key points • Paraburkholderia aromaticivorans AR20-38 successfully degrades four lignin monomers. • Successful degradation study at low (10°C) and moderate temperatures (20–30°C). • Biotechnological value: high yield of vanillic acid produced from ferulic acid.


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