The kidney in sarcoidosis

Oxford Textbook of Medicine ◽

10.1093/med/9780198746690.003.0494 ◽

2020 ◽

pp. 5012-5015

Author(s):

Ingeborg Hilderson ◽

Jan Donck

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Renal Insufficiency ◽

Calcium Metabolism ◽

Histological Finding ◽

Common Cause ◽

Calcium Deposits ◽

Important Disease ◽

Tubulointerstitial Inflammation ◽

Steroid Sparing

Sarcoidosis is associated with a broad spectrum of renal manifestations, but clinically important disease occurs in few patients. The most common cause of renal dysfunction is abnormal calcium metabolism: untreated chronic hypercalcaemia and hypercalciuria causes progressive tubulointerstitial inflammation with associated calcium deposits, leading to nephrocalcinosis, which is the leading cause of chronic kidney disease. Interstitial granulomatous nephritis is the most typical histological finding, but development of renal insufficiency is unusual. A range of glomerulopathies can be associated with sarcoidosis. When treatment is required, steroids are the first line, with various steroid-sparing agents used in cases that are refractory.

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Avaliação da Resiliência em Pacientes com Insuficiência Renal Crônica Submetidos à Hemodiálise / Assessment of Resilience in Patients With Chronic Kidney Disease Undergoing Hemodialysis

REVISTA CIÊNCIAS EM SAÚDE ◽

10.21876/rcsfmit.v6i1.461 ◽

1970 ◽

Vol 6 (1) ◽

pp. 5-13

Author(s):

Renata Izabel dos Santos ◽

Otávia Regina Souza Costa

Keyword(s):

Chronic Kidney Disease ◽

Renal Failure ◽

Health Status ◽

Chronic Renal Failure ◽

Kidney Disease ◽

Renal Insufficiency ◽

Social Economic ◽

Descriptive Study ◽

Psychological Resilience ◽

Resilience Scale

RESUMOObjetivo: Avaliar o nível de resiliência dos portadores de insuficiência renal crônica em tratamento de hemodiálise. Materiais e Métodos: Estudo prospectivo, quantitativo e de abordagem descritiva. A amostra foi constituída por 61 pacientes em tratamento dialítico. Para obtenção dos resultados, foi utilizada a escala de resiliência, desenvolvida por Wagnild e Young (1993) e adaptada por Pesce et al., (2005). Foi aplicado, também, um questionário para caracterização pessoal, familiar, social, econômica e de saúde do grupo. Resultados: Foi constatado que 61% dos pacientes apresentaram tendência à resiliência. O gênero masculino obteve maior pontuação, sugerindo maior tendência à resiliência, bem como os pacientes que são praticantes de uma religião. Conclusão: Os resultados assinalam que os pacientes em tratamento dialítico no hospital apresentam capacidade à resiliência, o que sugere melhor adaptação ao tratamento.Palavras-chave: Avaliação, Resiliência psicológica, Insuficiência renal crônica.ABSTRACTObjective: To evaluate de the level of resilience in patients with chronic renal failure undergoing dialysis. Materials and Methods: Prospective, quantitative and descriptive study. The sample consisted of 61 patients on dialysis. To obtain the results we used Resilience Scale developed by Wagnild and Young (1993) and adapted by Pesce et al., (2005). A questionnaire to characterize personal, familiar, social, economic and health status was applied. Results: It was found that 61% of patients showed trend to resilience. Males had higher scores, suggesting more likelihood to resilience, as well as patients who were practitioners of a religion. Conclusion: The results indicate that the majority of patients on dialysis have capability of resilience, which suggests better adaptation to treatment.Keywords: Evaluation, Psychological resilience, Chronic renal insufficiency.

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Relation of Aortic Valve Calcium to Chronic Kidney Disease (from the Chronic Renal Insufficiency Cohort Study)

The American Journal of Cardiology ◽

10.1016/j.amjcard.2015.02.011 ◽

2015 ◽

Vol 115 (9) ◽

pp. 1281-1286 ◽

Cited By ~ 26

Author(s):

Marie A. Guerraty ◽

Boyang Chai ◽

Jesse Y. Hsu ◽

Akinlolu O. Ojo ◽

Yanlin Gao ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Cohort Study ◽

Kidney Disease ◽

Aortic Valve ◽

Renal Insufficiency ◽

Chronic Renal Insufficiency

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Incidence of Acute Kidney Injury in Patients with Chronic Renal Insufficiency: Transcatheter versus Surgical Aortic Valve Replacement

Journal of Interventional Cardiology ◽

10.1155/2019/9780415 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Michael Catalano ◽

Dishen Lin ◽

Hugh Cassiere ◽

Nina Kohn ◽

Bruce Rutkin ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Acute Kidney Injury ◽

Kidney Disease ◽

Aortic Valve ◽

Renal Insufficiency ◽

Aortic Valve Replacement ◽

Valve Replacement ◽

Kidney Injury ◽

Surgical Aortic Valve Replacement ◽

Postoperative Aki

Objectives. The objective of this study is to determine incidence of acute kidney injury (AKI) associated with transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) in patients with preexisting chronic kidney disease. Background. The incidence of AKI in patients with preexisting renal insufficiency undergoing TAVR versus SAVR is not well described. Methods. All patients with preexisting chronic kidney disease who underwent SAVR for aortic stenosis with or without concomitant coronary artery bypass grafting or TAVR from 5/2008 to 6/2017. Patients requiring preoperative hemodialysis were excluded. Chronic kidney disease was defined as an estimated glomerular filtrate rate (eGFR) of < 60 mL/min/1.73 m2. The incidence of postoperative AKI was compared using the RIFLE classification system for acute kidney injury. Results. A total of 406 SAVR patients and 407 TAVR patients were included in this study. TAVR patients were older and had lower preoperative eGFR as compared to SAVR patients. Covariate adjustment using propensity score between the two groups showed that SAVR patients were more likely to have a more severe degree of postoperative AKI as compared to TAVR patients (OR = 4.75; 95% CI: 3.15, 7.17; p <.001). SAVR patients were more likely to require dialysis postoperatively as compared to TAVR patients (OR = 4.55; 95% CI: 1.29, 15.99; p <.018). Conclusion. In patients with preexisting chronic kidney disease, TAVR was associated with significantly less AKI as compared to SAVR.

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