Delirium

Author(s):  
Daniel Davis ◽  
Sarah Richardson ◽  
Esteban Sepulveda

Delirium is a common and severe neuropsychiatric syndrome of brain dysfunction characterized by acute and fluctuating inattention and other cognitive and perceptual deficits precipitated by acute illness. Despite being first described by Hippocrates more than two thousand years ago, there exists considerable uncertainty regarding the diagnosis of delirium due to our limited understanding of fundamental concepts, including its definition and pathophysiology. The ensuing lack of standardization results in delirium being frequently undiagnosed and significant misclassification bias in existing research. This chapter discusses the descriptive epidemiology of delirium, including methodological issues around case ascertainment in different population and clinical settings. There remains a lack of epidemiological research in the field, but we indicate the potential for observational longitudinal studies to address key questions on the population impact of delirium alongside fundamental questions of major importance to patients and their families regarding outcomes after delirium.

2000 ◽  
Vol 9 (3) ◽  
pp. 171-189 ◽  
Author(s):  
Mark Woodward ◽  
Jean Nursten ◽  
Paul Williams ◽  
Doug Badger

SummaryObjective – This paper reviews 28 studies on the epidemiology of homicide committed by mentally disordered people, taken from recent international academic literature. Methods – The studies included were identified as part of a wider systematic review of the epidemiology of offending combined with mental disorder. The main databases searched were Embase, Medline, HealthStar, Psyclit, Mental Health Abstracts, Applied Social Sciences Index and Abstracts, and Criminology Penology and Police Science Abstracts. A comprehensive search was made for studies published since 1990, supplemented with key studies from the 1980s identified through citation tracing and personal contacts. Results – A summary is given in tabular form of the content and quality of each study. There is then discussion of the studies in eight categories: descriptive studies, studies of trends, comparative studies amongst homicide offenders, amongst prisoners and including general populations, studies of homicide of relatives, follow-up studies, and studies of recidivism. Conclusions – There is an association of homicide with mental disorder, most particularly with certain manifestations of schizophrenia, antisocial personality disorder and drug or alcohol abuse. However, the quality of epidemiological research in this area is not adequate to answer key questions, and prediction of potential for homicide remains elusive. Further research is needed.


1984 ◽  
Vol 18 (3) ◽  
pp. 767-781
Author(s):  
Ina Rosenthal-Urey

This article discusses the methodological issues in the study of Mexican migration initiated by Cornelius and others in a recent issue of this journal (1982). It addresses two problems: the need to locate strategic regions in Mexico before field-work is begun; and the need to develop techniques for longitudinal studies of migration networks.


2017 ◽  
Vol 48 (1) ◽  
pp. 1-10 ◽  
Author(s):  
S. Woodhouse ◽  
A. Miah ◽  
M. Rutter

The main focus is on the assessment of the effects of early institutional care and compares three longitudinal studies from Romania, Greece and Hong Kong/China. The findings have been strikingly contrasting. The review asks if the risks are dependent on whether or not the institutional rearing is accompanied by gross pervasive deprivation (as it was in Romania) and investigates the methodological issues to explore the causal influence of the outcomes. Evidence is considered on changing institutional practices and the benefits of doing so. Comparison is made between institutions with major deprivation and those without global deprivation. A small number of studies are discussed that look at direct comparisons between institutional and community care. The empirical and conceptual implications of the findings are discussed.


1970 ◽  
Vol 30 (2) ◽  
pp. 577-578 ◽  
Author(s):  
Dean G. Kilpatrick

Although the Halstead Category Test is one of the best indicators of brain dysfunction among the subtests of the Halstead-Reitan Neuropsychological Test Battery, it has been used infrequently by psychologists in clinical settings. The feasibility of a short form was considered. For the test protocols of 41 Ss the product-moment correlation for errors on odd items and total errors was .90, on even items and total errors, .99. The split-half correlation was .97. Research on the discriminative power of a short form was discussed; a short form is apparently feasible for use by the psychologist.


Author(s):  
Thais Minett ◽  
Blossom Stephan ◽  
Carol Brayne

Epidemiology is the foundation of public health and rational planning of services. In the field of old age psychiatry, the information provided by epidemiological research has been highly influential. As the world older population is growing proportionally faster than the other age segments, there is a continuous need for further epidemiological research in old age psychiatry. Neuropsychiatric conditions, such as depression and dementia, cognitive impairment, behavioural and functional decline, place a considerable onus on the health, social and economic systems. This chapter presents some of the world demographic data and basic epidemiological concepts, discusses some methodological issues in the epidemiology of mental disorders in old age, and presents a summary of many of the most important studies in this field.


2015 ◽  
Vol 4 (1_suppl) ◽  
pp. gahmj.2015.022. ◽  
Author(s):  
David Muehsam ◽  
Gaétan Chevalier ◽  
Tiffany Barsotti ◽  
Blake T. Gurfein

Advances in biophysics, biology, functional genomics, neuroscience, psychology, psychoneuroimmunology, and other fields suggest the existence of a subtle system of “biofield” interactions that organize biological processes from the subatomic, atomic, molecular, cellular, and organismic to the interpersonal and cosmic levels. Biofield interactions may bring about regulation of biochemical, cellular, and neurological processes through means related to electromagnetism, quantum fields, and perhaps other means of modulating biological activity and information flow. The biofield paradigm, in contrast to a reductionist, chemistry-centered viewpoint, emphasizes the informational content of biological processes; biofield interactions are thought to operate in part via low-energy or “subtle” processes such as weak, nonthermal electromagnetic fields (EMFs) or processes potentially related to consciousness and nonlocality. Biofield interactions may also operate through or be reflected in more well-understood informational processes found in electroencephalographic (EEG) and electrocardiographic (ECG) data. Recent advances have led to the development of a wide variety of therapeutic and diagnostic biofield devices, defined as physical instruments best understood from the viewpoint of a biofield paradigm. Here, we provide a broad overview of biofield devices, with emphasis on those devices for which solid, peer-reviewed evidence exists. A subset of these devices, such as those based upon EEG- and ECG-based heart rate variability, function via mechanisms that are well understood and are widely employed in clinical settings. Other device modalities, such a gas discharge visualization and biophoton emission, appear to operate through incompletely understood mechanisms and have unclear clinical significance. Device modes of operation include EMF-light, EMF-heat, EMF-nonthermal, electrical current, vibration and sound, physical and mechanical, intentionality and nonlocality, gas and plasma, and other (mode of operation not well-understood). Methodological issues in device development and interfaces for future interdisciplinary research are discussed. Devices play prominent cultural and scientific roles in our society, and it is likely that device technologies will be one of the most influential access points for the furthering of biofield research and the dissemination of biofield concepts. This developing field of study presents new areas of research that have many important implications for both basic science and clinical medicine.


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