Rheumatoid arthritis

2011 ◽  
pp. 233-258
Author(s):  
Alan J. Hakim ◽  
Gavin P.R. Clunie ◽  
Inam Haq
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Trials ◽  
Rheumatoid Factor ◽  
Clinical Features ◽  
Positive Rheumatoid Factor ◽  
Incidence Prevalence

Disease criteria and epidemiology for use in clinical trials 234 Incidence, prevalence, and morbidity 235 The clinical features of rheumatoid arthritis 236 Organ disease in rheumatoid arthritis 238 The evaluation and treatment of rheumatoid arthritis 242 Polyarticular arthritis in children with a positive rheumatoid factor ...

scholarly journals The Relationship Between Hyperglycemia and the Rheumatoid Factor in the Serum of Diabetic Patients

2009 ◽  
Vol 6 (1) ◽  
pp. 99-105
Author(s):  
Baghdad Science Journal
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Healthy Subjects ◽  
Diabetic Patients ◽  
Diabetic Mellitus ◽  
Positive Rheumatoid Factor ◽  
Common Diseases ◽  
Males And Females ◽  
The Relationship ◽  
Apparently Healthy

This study was conducted to determine the relationship between two most common diseases in Iraqis patients , which are Diabetic mellitus (DM) and Rheumatoid Arthritis (RA); seeking rheumatoid factor in hyperglycemic sera. The results revealed that ; 62.5% of hyperglycemic (HG) patients had positive rheumatoid factor (RF) . No difference in number between both gender of HG patients (20 males and 20 females ) , RF reaction was nearly similar in males and females of HG patients ( 12 &13 respectively ) . Only 40% out of patient controls had positive RF . None of the apparently healthy subjects had positive RF .

A positive rheumatoid factor and X-ray damage predict focal and generalized bone loss in patients with mild rheumatoid arthritis followed over two years

Bone ◽  
2008 ◽  
Vol 43 ◽  
pp. S85-S86
Author(s):  
Huiqiong Zhou ◽  
Ruyu Yao ◽  
H. Wilson ◽  
S. Song ◽  
B. Breidahl ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Loss ◽  
Rheumatoid Factor ◽  
X Ray ◽  
Positive Rheumatoid Factor

Rheumatoid arthritis

2019 ◽  
pp. 81-102
Author(s):  
Mike Backhouse ◽  
Heidi Siddle
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Trials ◽  
Clinical Features ◽  
Disease Onset ◽  
Management Options ◽  
Histological Changes ◽  
Foot Disease ◽  
Future Direction ◽  
Disease Specific ◽  
Specific Management

In this chapter, we will cover rheumatoid arthritis. First we will describe the epidemiology, aetiology, and pathogenesis of rheumatoid arthritis, followed by the histological changes in joints. Clinical features of the disease are described and how it affects the foot and ankle at disease onset and in the early stages. The disability and impact of the disease is considered prior to describing systemic treatment methods. Specific foot disease associated with rheumatoid arthritis is covered, split by area of the foot. Imaging requirements are outlined, including disease-specific considerations, and specific management options are discussed. Finally, clinical trials and the future direction of research are covered.

scholarly journals A core set of risk factors in individuals at risk of rheumatoid arthritis: a systematic literature review informing the EULAR points to consider for conducting clinical trials and observational studies in individuals at risk of rheumatoid arthritis

RMD Open ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. e001768
Author(s):  
Kulveer Mankia ◽  
Heidi Siddle ◽  
Andrea Di Matteo ◽  
Deshiré Alpízar-Rodríguez ◽  
Joel Kerry ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
At Risk ◽  
Clinical Trials ◽  
Risk Factor ◽  
Literature Review ◽  
Clinical Features ◽  
Literature Search ◽  
Subclinical Inflammation ◽  
Core Set

BackgroundThere is significant interest in determining risk factors in individuals at risk of rheumatoid arthritis (RA). A core set of risk factors for clinical arthritis development has not been defined.MethodsA literature search and systematic literature review (SLR) was conducted to identify risk factors in individuals at risk of RA using Medline, Embase, PubMed and Central databases.Results3854 articles were identified by the literature search. After screening of titles, 138 abstracts were reviewed and 96 articles finally included. Fifty-three articles included data on risk factors including autoantibodies, subclinical inflammation on imaging, clinical features, serum and cellular biomarkers and genetic markers. Risk factors were dependent on the at-risk population. There was good evidence for serum anticitrullinated protein antibodies (ACPA) levels, as risk factors for arthritis in all at-risk populations (n=13 articles). Subclinical inflammation on ultrasound (n=12) and MRI (n=6) was reported as a risk factor in multiple studies in at-risk individuals with musculoskeletal (MSK) symptoms and undifferentiated arthritis (UA). Clinical features were reported as a risk factor in at-risk individuals with MSK symptoms and UA (n=13). Other risk factors, including serum and cellular markers were less frequently reported.ConclusionsRisk factors for arthritis development in RA are specific to the at-risk population. Serum ACPA confers risk in all populations; subclinical inflammation on imaging and clinical features confer risk in at-risk individuals with MSK symptoms. This SLR informed the EULAR taskforce for points to consider on conducting clinical trials and studies in individuals at risk of RA.

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