Priapism

Mapping Intimacies ◽

10.1093/med/9780199659579.003.0106 ◽

2017 ◽

Author(s):

Asif Muneer ◽

David Ralph

Keyword(s):

Muscle Function ◽

Arterial Embolization ◽

The Other ◽

Medical Emergency ◽

Recreational Drug ◽

Selective Arterial Embolization ◽

Arterial Blood ◽

Smooth Muscle Function ◽

Recreational Drug Use ◽

Stuttering Priapism

Priapism is rare and is a medical emergency. Ischaemic priapism is the commonest subtype with haematological abnormalities, psychotropic or recreational drug use and malignancy being the other common aetiologies. Emergency decompression of this compartment syndrome is required to preserve cavernosal smooth muscle function and this should ideally be performed as soon as possible. The degree of resultant erectile dysfunction is related to the duration of the priapism. Non-ischaemic priapism is an unregulated inflow of arterial blood, often as a result of perineal trauma and a lacerated cavernosal vessel. Selective arterial embolization should be performed and results are usually excellent. The final subtype is stuttering priapism, the cause of which is often unknown and a variety of methods will be discussed for its treatment.

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Cullin-3 Regulates Vascular Smooth Muscle Function and Arterial Blood Pressure via PPARγ and RhoA/Rho-Kinase

Cell Metabolism ◽

10.1016/j.cmet.2012.08.011 ◽

2012 ◽

Vol 16 (4) ◽

pp. 462-472 ◽

Cited By ~ 66

Author(s):

Christopher J. Pelham ◽

Pimonrat Ketsawatsomkron ◽

Séverine Groh ◽

Justin L. Grobe ◽

Willem J. de Lange ◽

...

Keyword(s):

Blood Pressure ◽

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Arterial Blood Pressure ◽

Muscle Function ◽

Rho Kinase ◽

Arterial Blood ◽

Smooth Muscle Function ◽

Cullin 3

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Recent advances in the management of priapism

F1000Research ◽

10.12688/f1000research.12828.1 ◽

2018 ◽

Vol 7 ◽

pp. 37 ◽

Cited By ~ 4

Author(s):

Asif Muneer ◽

Hussain M. Alnajjar ◽

David Ralph

Keyword(s):

Erectile Dysfunction ◽

Muscle Function ◽

Penile Erection ◽

Medical Intervention ◽

Physiological Mechanisms ◽

Sexual Stimulation ◽

Ischemic Priapism ◽

Smooth Muscle Function ◽

Urological Emergency ◽

Stuttering Priapism

Priapism is an uncommon urological emergency that can lead to permanent impotence if prompt presentation and medical intervention is not performed. It is a breakdown of the usual physiological mechanisms controlling penile tumescence and detumescence, leading to a prolonged penile erection (>4 hours) that is unrelated to sexual stimulation. Currently, there are three accepted subtypes: ischaemic, non-ischaemic, and stuttering priapism, which is also known as recurrent ischemic priapism. The aim of treatment is the immediate resolution of the painful erection and the preservation of cavernosal smooth muscle function in order to prevent cavernosal fibrosis, which can lead to penile shortening and permanent erectile dysfunction.

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Recreational Drugs Policy

It's the Government, Stupid! ◽

10.1332/policypress/9781529206388.003.0006 ◽

2020 ◽

pp. 113-134

Author(s):

Keith Dowding

Keyword(s):

Drug Use ◽

The Other ◽

Social Effects ◽

Recreational Drug ◽

Recreational Drugs ◽

The Social ◽

Recreational Drug Use ◽

The Usa ◽

History Of ◽

Drug Decriminalization

This chapter examines the history of regulating recreational drugs in the USA, UK and Australia. It shows that the criminalization of recreational drugs is a relatively recent phenomenon, based not on citizen welfare but on fears that drugs affect the nation’s ability to wage war, whilst some early legislation was openly racist. It argues that the continued justification of drug criminalization is moralistic and has racist underpinnings. It suggests that whilst the social problems of recreational drug use are serious, they are no more serious than those of alcohol or gambling, and legalization has many advantages over continued criminalization. It examines the results of drug decriminalization in Portugal, and the likely practicality and social effects should recreational drugs be legalized. It argues that such legalization would also require careful regulation, much as we have for drugs manufactured for medical purposes. It compares the policy stance of governments on recreational drugs to that on the other issues discussed in this book.

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Calculating The Risk: Recreational Drug Use Among Clubbers In The South East of England

PsycEXTRA Dataset ◽

10.1037/e634232007-001 ◽

2003 ◽

Cited By ~ 4

Author(s):

Anne Deehan ◽

Esther Saville

Keyword(s):

Drug Use ◽

Recreational Drug ◽

The South ◽

Recreational Drug Use

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Behind closed doors: Risk and recreational drug use in rural Northern Ireland.

Rural Mental Health ◽

10.1037/rmh0000070 ◽

2017 ◽

Vol 41 (2) ◽

pp. 97-109 ◽

Cited By ~ 1

Author(s):

Christina O'Neill

Keyword(s):

Northern Ireland ◽

Drug Use ◽

Recreational Drug ◽

Recreational Drug Use

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THE EFFICACY OF SELECTIVE ARTERIAL EMBOLIZATION IN THE MANAGEMENT OF DIVERTICULAR BLEEDING

10.26226/morressier.59a6b34cd462b80290b55b03 ◽

2017 ◽

Author(s):

Yuichi Fukami

Keyword(s):

Arterial Embolization ◽

Diverticular Bleeding ◽

Selective Arterial Embolization

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Does the Presence of On-Site Medical Services at Outdoor Music Festivals Affect Attendees’ Planned Alcohol and Recreational Drug Use?

Prehospital and Disaster Medicine ◽

10.1017/s1049023x21000613 ◽

2021 ◽

pp. 1-5

Author(s):

Alison Hutton ◽

Matthew Brendan Munn ◽

Sydney White ◽

Peter Kara ◽

Jamie Ranse

Keyword(s):

Substance Use ◽

Drug Use ◽

Great Majority ◽

Safety Net ◽

Medical Services ◽

Future Research ◽

Recreational Drug ◽

Recreational Drugs ◽

Mandatory Requirement ◽

Recreational Drug Use

Abstract Background: Dedicated on-site medical services have long been recommended to improve health outcomes at mass-gathering events (MGEs). In many countries, they are being reviewed as a mandatory requirement. While it is known that perceptions of risk shape substance use plans amongst outdoor music festival (OMF) attendees, it is unclear if attendees perceive the presence of on-site medical services as a part of the safety net. The aim of this paper is to better understand whether attendees’ perceptions of on-site medical services influence high-risk behaviors like alcohol and recreational drug use at OMFs. Method: A questionnaire was distributed to a random sample of attendees entering and attending two separate 20,000-person OMFs; one in Canada (Festival A) and one in New Zealand (Festival B). Responses focused on demographics, planned alcohol and recreational drug use, perceptions of medical services, and whether the absence of medical services would impact attendees’ planned substance use. Results: A total of 851 (587 and 264 attendees for Festival A and Festival B, respectively) attendees consented and participated. Gender distribution was equal and average ages were 23 to 25. At Festival A, 48% and 89% planned to use alcohol and recreational drugs, respectively, whereas at Festival B, it was 92% and 44%. A great majority were aware and supportive of the presence of medical services at both festivals, and a moderate number considered them a factor in attendance and something they would not attend without. There was significant (>10%) agreement (range 11%-46%; or 2,200-9,200 attendees for a 20,000-person festival) at both festivals that the absence of medical services would affect attendees’ planned use of alcohol and recreational drugs. Conclusions: This study found that attendees surveyed at two geographically and musically distinct OMFs had high but differing rates of planned alcohol and recreational drug use, and that the presence of on-site medical services may impact attendees’ perceptions of substance use risk. Future research will aim to address the limitations of this study to clarify these findings and their implications.

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Combined resection of the hepatic artery without reconstruction in pancreaticoduodenectomy: a case report of pancreatic cancer with an aberrant hepatic artery

Surgical Case Reports ◽

10.1186/s40792-020-00997-5 ◽

2020 ◽

Vol 6 (1) ◽

Author(s):

Tadao Kuribara ◽

Tatsuo Ichikawa ◽

Kiyoshi Osa ◽

Takeshi Inoue ◽

Satoshi Ono ◽

...

Keyword(s):

Pancreatic Cancer ◽

Hepatic Artery ◽

Locally Advanced ◽

Pancreatic Head ◽

Arterial Embolization ◽

Arterial Blood Flow ◽

Temporary Increase ◽

Combined Resection ◽

Arterial Blood ◽

Arterial Resection

Abstract Background Pancreaticoduodenectomy (PD) is rarely performed for pancreatic cancer with hepatic arterial invasion owing to its poor prognosis and high surgical risks. Although there has been a recent increase in the reports of PD combined with hepatic arterial resection due to improvements in disease prognosis and operative safety, PD with major arterial resection and reconstruction is still considered a challenging treatment. Case presentation A 61-year-old man with back pain was diagnosed with pancreatic head and body cancer. Although distant metastasis was not confirmed, the tumor had extensively invaded the hepatic artery; therefore, we diagnosed the patient with locally advanced unresectable pancreatic cancer. After gemcitabine plus nab-paclitaxel (GnP) therapy, the tumor considerably decreased in size from 35 to 20 mm. Magnetic resonance imaging revealed a gap between the tumor and the hepatic artery. Tumor marker levels returned to their normal range, and we decided to perform conversion surgery. In this case, an artery of liver segment 2 (A2) had branched from the left gastric artery; therefore, we decided to preserve A2 and perform PD combined with hepatic arterial resection without reconstruction. After four cycles of GnP therapy, we performed hepatic arterial embolization to prevent postoperative ischemic complications prior to surgery. Immediately after embolization, collateral arterial blood flow to the liver was observed. Operation was performed 19 days after embolization. Although there was a temporary increase in liver enzyme levels and an ischemic region was found near the surface of segment 8 of the liver after surgery, no liver abscess developed. The postoperative course was uneventful, and S-1 was administered for a year as adjuvant chemotherapy. The patient is currently alive without any ischemic liver events and cholangitis and has not experienced recurrence in the past 4 years since the surgery. Conclusions In PD for pancreatic cancer with hepatic arterial invasion, if a part of the hepatic artery is aberrant and can be preserved, combined resection of the common and proper hepatic artery without reconstruction might be feasible for both curability and safety.

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