scholarly journals Investigating the lower extremity–related anaerobic exercise capacity and functional status in adult patients with familial Mediterranean fever

2021 ◽  
Author(s):  
Merve Eylul Acar ◽  
Deniz Bayraktar ◽  
Sercan Gucenmez ◽  
Devrim Can Sarac ◽  
Nurullah Buker ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Lower Extremity ◽  
Functional Status ◽  
Exercise Capacity ◽  
Adult Patients ◽  
Anaerobic Exercise ◽  
Walking Distance ◽  
Chair Stand ◽  
Stand Test ◽  
Chair Stand Test

ABSTRACT Objectives No studies examined the lower extremity–related anaerobic exercise capacity or functional status in adult patients with FMF. Methods Twenty-four patients with FMF (12 males) and 24 age–sex-matched healthy controls (13 males) were included in the study. Lower extremity–related anaerobic exercise capacity was assessed by using Wingate Anaerobic Test. Lower extremity–related functional status was examined by using 9-Step Stair Climb Test, 10-Repetition Chair Stand Test, and Six-Minute Walking Distance. Muscle strength of hip flexors, hip extensors, knee flexors, and knee extensors were evaluated by using a hand-held dynamometer. Results Patients with FMF had significantly poorer results in all anaerobic exercise capacity parameters and functional status assessments (P < 0.05), except muscle strength measurements (P > 0.05). Both average and peak anaerobic exercise capacities correlated significantly with all muscle strength measurements, 9-Step Stair Climb Test, 10-Repetition Chair Stand Test times, and Six-Minute Walk Distances (P < 0.05) in patients with FMF. Conclusion Lower extremity–related anaerobic exercise capacity and functional status seem to be diminished in adult patients with FMF. Evaluating these parameters may be beneficial for planning more appropriate and individualized treatment regimens such as patient education and exercise counselling for patients with FMF.

scholarly journals AB0862-HPR THE RELATIONSHIP BETWEEN ANAEROBIC EXERCISE CAPACITY AND LOWER EXTREMITY FUNCTIONALITY IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1454.2-1455
Author(s):  
M. E. Acar ◽  
D. Bayraktar ◽  
S. Gucenmez ◽  
D. C. Saraç ◽  
N. Buker ◽  
...  
Keyword(s):  
Familial Mediterranean Fever ◽  
Lower Extremity ◽  
Functional Status ◽  
Exercise Capacity ◽  
Peak Power ◽  
Average Power ◽  
Anaerobic Capacity ◽  
Anaerobic Exercise ◽  
Walking Distance ◽  
Mediterranean Fever

Background:Familial Mediterranean fever (FMF) is an auto-inflammatory disease commonly affects people from Mediterranean basin. It is characterized by acute self-limiting inflammatory attacks of serous membranes. The disease is commonly associated with musculoskeletal symptoms of lower extremities such as arthritis, exercise induced leg pain, as well as protracted febrile myalgia. The term of anaerobic exercise capacity describes the ability of performing quick and explosive tasks such as stair climbing and brisk walking. It is well known that anaerobic exercise capacity is closely related to functional status.Objectives:To assess the relationship between anaerobic exercise capacity and lower extremity functionality in patients with FMF.Methods:Twenty-eight FMF patients (57% female) were included in the study. Median age was 33.5 (IQR 25/75: 23.3/44.3) years, median body mass index was 24.3 (IQR 25/75: 21.0/27.8) kg/m2, median time since symptom onset was 20.0 (IQR 25/75: 11.5/24.5) years, median time since diagnosis was 10.0 (IQR 25/75: 3.75/17.5) years, and median colchicine dosage was 1.5 (IQR 25/75: 1.0/1.5) mg/day. Anaerobic exercise capacity was measured with Wingate Anaerobic Test by using a cycle ergometer. Peak power (watt/kg) and average power (watt/kg) were calculated. Stair climbing, standing from a chair, and walking were assessed by using 9-step stair climb test, 10-repetition chair stand test, and 6-minute walking distance, respectively. Spearman’s rank-order correlation test was used to analyse the relationships between anaerobic exercise capacity and lower extremity functional tests.Results:The results of the anaerobic exercise capacity and lower extremity functional test scores of patients with FMF were summarized in table 1. Moderate relationships were found between both peak and average anaerobic exercise capacities and lower extremity functional status tests (Table 1, p<0.05). Six-minute walking distance has the strongest association with both peak (rho: .672, p<0.001) and average (rho: .689, p<0.001) anaerobic exercise capacity.Table 1.Anaerobic exercise capacity scores and lower extremity functionality as well as the relationships between anaerobic capacity and functional tests in patient with familial Mediterranean fever.CharacteristicsMedian (IQR 25/75)(n:28)The correlation results, rho, p valuesPeak Power(watt/kg)Average Power (watt/kg)9-step stair climb test (seconds)5.7 (5.1/6.4)-.590*-.648*p:0.001p: 0.00110-repetition chair stand test (seconds)16.6 (13.7/18.7)-.493*-.476*p:0.008p:0.0106-minute walking distance (meters)594.1 (551.1/643.3).672*.689*p<0.001p<0.001Peak power (watt/kg)5.8 (4.1/7.9)Average power (watt/kg)4.6 (3.1/5.9)IQR 25/75: Interquartile range between 25th and 75th percentiles; kg: kilograms, *Spearman’s rank-order correlation test, p<0.05.Conclusion:According to our results, anaerobic exercise capacity is related to lower extremity functional status in patients with FMF. Improving anaerobic capacity by using optimal rehabilitation programs including speed and agility exercises may help to improve anaerobic exercise capacity, and consequently lower extremity functionality in those patients.Disclosure of Interests:None declared

Decrease in physical performance during the hospitalisation phase of haematopoietic stem cell transplantation

2019 ◽  
Vol 26 (11) ◽  
pp. 1-12 ◽  
Author(s):  
Carine Lumi ◽  
Fabrício Edler Macagnan ◽  
Adriana Kessler ◽  
Priscila De Toni ◽  
Adriana Maisonnave Raffone
Keyword(s):  
Stem Cell ◽  
Muscle Strength ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Physical Performance ◽  
Haematopoietic Stem Cell Transplantation ◽  
Haematopoietic Stem Cell ◽  
Chair Stand ◽  
Stand Test ◽  
Chair Stand Test

Background/Aims The negative impact caused by haematopoietic stem cell transplantation still requires further investigation. This study aims to investigate the effects of this procedure on skeletal muscle strength, functional performance and fatigue sensation in the hospitalisation phase. Methods This prospective cohort study aimed to assess physical performance by measuring ventilatory muscle strength, peripheral muscle strength and fatigue in patients who underwent haematopoietic stem cell transplantation. Results The sample consisted of 30 patients of both sexes (63% men) with a mean age of 48.6 ± 13.2 years. Maximal inspiratory pressure and expiratory pressure decreased by 19% and 16%, respectively (P<0.001). There was a 16% reduction in handgrip strength in the second assessment (P<0.001), as well as a reduction of 30.6% in the 30-Second Chair Stand Test (P<0.001). The fatigue test score increased exponentially (60%) (P<0.001). Individuals with worse results in the 30-Second Chair Stand Test remained hospitalised for a longer period than those with better results (P=0.024). Conclusions This study concluded that after the transplantation of haematopoietic stem cells there was a relevant reduction in the results of the applied tests, as well as an increase in fatigue.

scholarly journals Diagnosis of sarcopenia in primary health care

2020 ◽  
Vol 63 (10) ◽  
pp. 633-641
Author(s):  
Chang Won Won
Keyword(s):  
Primary Care ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Handgrip Strength ◽  
Muscle Performance ◽  
Chair Stand ◽  
Stand Test ◽  
Chair Stand Test ◽  
Primary Care Settings ◽  
Increased Risk

With aging, there is a loss of skeletal muscle mass and function, which leads to an increased risk of falls, fractures, long-term institutional care, cardiovascular and metabolic diseases, and even mortality. Sarcopenia has been defined as a condition characterized by low muscle mass together with low muscle strength and/or low muscle performance. In 2019, the Asian Working Group for Sarcopenia (AWGS) published a consensus paper on the diagnosis and treatment of sarcopenia. The AWGS 2019 guideline, in particular, presented strategies for case-finding and assessment, which could aid in the diagnosis of possible sarcopenia in primary care settings. AWGS 2019 proposed an algorithm that recommends calf circumference measurement (cut-off <34 cm in men, <33 cm in women) or the SARC-F (strength, assistance in walking, rising from a chair, climbing stairs, falls) questionnaire (cut-off ≥4), followed by handgrip strength measurement (cut-off <28 kg in men, <18 kg in women) or the 5-time chair stand test (≥12 seconds). Finally, “possible sarcopenia” is defined by either low muscle strength (handgrip strength) or low physical performance (5-time chair stand test). This paper will address the way in which sarcopenic patients can be identified and assessed practically in primary care settings.

scholarly journals Efektivitas senam vitalisasi otak terhadap kebugaran jasmani pada lansia demensia

2020 ◽  
Vol 6 (2) ◽  
pp. 364-374
Author(s):  
Mustika Fitri ◽  
Upik Rahmi ◽  
Pipit Pitriani ◽  
Afianti Sulastri
Keyword(s):  
Muscle Strength ◽  
The Elderly ◽  
P Value ◽  
Walk Test ◽  
Chair Stand ◽  
Stand Test ◽  
Chair Stand Test

Aktivitas fisik akan meningkatkan kebugaran jasmani sehingga dapat memperlambat perkembangan kognitif dan penurunan fisik lansia dengan demensia. Demensia merupakan sindrom neurodegeneratif yang timbul karena adanya kelainan bersifat kronis dan progesif disertai dengan gangguan fungsi luhur multipel seperti kalkulasi, kapasitas belajar, bahasa, dan mengambil keputusan. Penelitian ini bertujuan untuk mengetahui kebugaran jasmani lansia dengan demensia pasca aktivitas fisik dengan senam vitalisasi otak. Metode yang digunakan dalam penelitian ini yaitu Metode Experimental. 10 subjek yang berusia 60 – 85 tahun dengan demensia ringan diberi perlakuan senam vitalisasi otak selama 12 kali dengan durasi waktu 25 menit. Setelah melakukan aktivitas fisik dilakukan pemeriksaan tes kebugaran jasmani (testing the elderly) yang terdiri dari: 6 minutes walk test (6 MWT), flexibility: Chair seat and reach test (CSRT), Muscle strength and endurance: Chair stand test (CST), dan Arm curl test (ACT), koordinasi dan kelincahan, 8 Foot up and go test (8 FUGT). Hasil penelitian dengan menggunakan uji T menunjukkan bahwa tes kebugaran memberikan hasil yang signifikan pada tes CST, CSRT (p value 0,0296) dan 8 FUGT 6MWT (pvalue 0,0229) pada tingkat kepercayaan 95%.  Kesimpulannya, aktivitas fisik vitalisasi otak berpengaruh terhadap kebugaran jasmani dengan perbaikan tonus otot dan kognitif pada lansia dengan demensia.

scholarly journals Relationship between malnutrition and possible sarcopenia in the AWGS 2019 consensus affecting mortality in hemodialysis patients: a prospective cohort study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kenichi Kono ◽  
Yoshifumi Moriyama ◽  
Hiroki Yabe ◽  
Ayaka Hara ◽  
Takeki Ishida ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Physical Performance ◽  
Roc Curve ◽  
Handgrip Strength ◽  
Hemodialysis Patients ◽  
Youden Index ◽  
Chair Stand ◽  
Stand Test ◽  
Chair Stand Test ◽  
The Relationship

Abstract Background The first objective of this study was to determine the relationship between muscle strength or physical performance and mortality, and the second objective was to show the relationship of Geriatric Nutritional Risk Index (GNRI) to muscle strength and physical performance decline. Methods We examined handgrip, the 5-times chair stand test, and GNRI in 635 maintenance hemodialysis patients and followed up for 72 months. Predictors for all-cause death were examined using Kaplan-Meier analysis and Cox proportional analysis. The relationship between possible sarcopenia and nutritional disorder (GNRI) was constructed receiver operating characteristic (ROC) curve. We used the Youden index to determine the optimal cutoff points for GNRI. Results The multivariate Cox proportional hazard analysis revealed that the GNRI did not show any significance, although handgrip (HR 3.61, 95% CI 1.70–7.68, p < 0.001) and the 5-times chair stand test (HR 1.71 95% CI 1.01–2.90, p = 0.045) were significant predictors for mortality. On the evaluation of possible sarcopenia by handgrip strength, the area under curve (AUC) on ROC curve analysis were 0.68 (95% CI 0.64–0.72), and 5-chair stand, the AUC on ROC were 0.55 (95% CI 0.51–0.60). The cut-off value for the GNRI discriminating those at possible sarcopenia by handgrip strength based on the Youden index was 91.5. Conclusions Our study suggests that the handgrip strength test of the AWGS 2019 sarcopenia consensus was a simple and useful tool to predict mortality in chronic hemodialysis patients. Furthermore, GNRI assessment can be a useful tool for screening before assessing possible sarcopenia when it is difficult to perform SARC-F to all patients.

scholarly journals The 30-s chair stand test can be a useful tool for screening sarcopenia in elderly Japanese participants

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shuji Sawada ◽  
Hayao Ozaki ◽  
Toshiharu Natsume ◽  
Pengyu Deng ◽  
Toshinori Yoshihara ◽  
...  
Keyword(s):  
Muscle Strength ◽  
The Elderly ◽  
Knee Extension ◽  
Optimal Number ◽  
Cross Sectional ◽  
Chair Stand ◽  
Stand Test ◽  
Diagnostic Score ◽  
Chair Stand Test ◽  
Elderly Japanese

Abstract Background Low muscle strength has been focused on as an essential characteristic of sarcopenia, and the 30-s chair stand test (CS-30) could be a particularly useful test for assessing muscle strength. While it is speculated to be a beneficial tool for the assessment of sarcopenia, this remains to be verified. In this study, we examined the reliability and optimal diagnostic score of the CS-30 for assessing sarcopenia in elderly Japanese participants. Methods This cross-sectional study included 678 participants (443 females and 235 males) who underwent the test for sarcopenia as per the Asian Working Group for Sarcopenia (AWGS) 2019, the CS-30 test, and the isometric knee-extension muscle strength test. ROC analysis was used to estimate the optimal CS-30 scores at which sarcopenia was detected. Results CS-30 scores were positively associated with sarcopenia (OR: 0.88; 95% CI:0.82–0.93). The AUC of the CS-30 for sarcopenia definition were 0.84 (p < 0.001) for females and 0.80 (p < 0.001) for males. The optimal number of stands in the CS-30 that predicted sarcopenia was 15 for females (sensitivity, 76.4%; specificity, 76.8%) and 17 for males (sensitivity, 75.0%; specificity, 71.7%). Conclusions The CS-30 was found to be a reliable test for sarcopenia screening in the elderly Japanese population.

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