scholarly journals Diagnosis of sarcopenia in primary health care

2020 ◽  
Vol 63 (10) ◽  
pp. 633-641
Author(s):  
Chang Won Won

With aging, there is a loss of skeletal muscle mass and function, which leads to an increased risk of falls, fractures, long-term institutional care, cardiovascular and metabolic diseases, and even mortality. Sarcopenia has been defined as a condition characterized by low muscle mass together with low muscle strength and/or low muscle performance. In 2019, the Asian Working Group for Sarcopenia (AWGS) published a consensus paper on the diagnosis and treatment of sarcopenia. The AWGS 2019 guideline, in particular, presented strategies for case-finding and assessment, which could aid in the diagnosis of possible sarcopenia in primary care settings. AWGS 2019 proposed an algorithm that recommends calf circumference measurement (cut-off <34 cm in men, <33 cm in women) or the SARC-F (strength, assistance in walking, rising from a chair, climbing stairs, falls) questionnaire (cut-off ≥4), followed by handgrip strength measurement (cut-off <28 kg in men, <18 kg in women) or the 5-time chair stand test (≥12 seconds). Finally, “possible sarcopenia” is defined by either low muscle strength (handgrip strength) or low physical performance (5-time chair stand test). This paper will address the way in which sarcopenic patients can be identified and assessed practically in primary care settings.

2018 ◽  
pp. 1-6
Author(s):  
S.M.L.M. Looijaard ◽  
S.J. Oudbier ◽  
E.M. Reijnierse ◽  
G.J. Blauw ◽  
C.G.M. Meskers ◽  
...  

Background: Sarcopenia is highly prevalent in the older population and is associated with several adverse health outcomes. Equipment to measure muscle mass and muscle strength to diagnose sarcopenia is often unavailable in clinical practice due to the related expenses while an easy physical performance measure to identify individuals who could potentially have sarcopenia is lacking. Objectives: This study aimed to assess the association between physical performance measures and definitions of sarcopenia in a clinically relevant population of geriatric outpatients. Design, setting and participants: A cross-sectional study was conducted, consisting of 140 community-dwelling older adults that were referred to a geriatric outpatient clinic. No exclusion criteria were applied. Measurements: Physical performance measures included balance tests (side-by-side, semi-tandem and tandem test with eyes open and -closed), four-meter walk test, timed up and go test, chair stand test, handgrip strength and two subjective questions on mobility. Direct segmental multi-frequency bioelectrical impedance analysis was used to measure muscle mass. Five commonly used definitions of sarcopenia were applied. Diagnostic accuracy was determined by sensitivity, specificity and area under the curve.Results: Physical performance measures, i.e. side-by-side test, tandem test, chair stand test and handgrip strength, were associated with at least one definition of sarcopenia. Diagnostic accuracy of these physical performance measures was poor. Conclusions: Single physical performance measures could not identify older individuals with sarcopenia, according to five different definitions of sarcopenia.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kenichi Kono ◽  
Yoshifumi Moriyama ◽  
Hiroki Yabe ◽  
Ayaka Hara ◽  
Takeki Ishida ◽  
...  

Abstract Background The first objective of this study was to determine the relationship between muscle strength or physical performance and mortality, and the second objective was to show the relationship of Geriatric Nutritional Risk Index (GNRI) to muscle strength and physical performance decline. Methods We examined handgrip, the 5-times chair stand test, and GNRI in 635 maintenance hemodialysis patients and followed up for 72 months. Predictors for all-cause death were examined using Kaplan-Meier analysis and Cox proportional analysis. The relationship between possible sarcopenia and nutritional disorder (GNRI) was constructed receiver operating characteristic (ROC) curve. We used the Youden index to determine the optimal cutoff points for GNRI. Results The multivariate Cox proportional hazard analysis revealed that the GNRI did not show any significance, although handgrip (HR 3.61, 95% CI 1.70–7.68, p < 0.001) and the 5-times chair stand test (HR 1.71 95% CI 1.01–2.90, p = 0.045) were significant predictors for mortality. On the evaluation of possible sarcopenia by handgrip strength, the area under curve (AUC) on ROC curve analysis were 0.68 (95% CI 0.64–0.72), and 5-chair stand, the AUC on ROC were 0.55 (95% CI 0.51–0.60). The cut-off value for the GNRI discriminating those at possible sarcopenia by handgrip strength based on the Youden index was 91.5. Conclusions Our study suggests that the handgrip strength test of the AWGS 2019 sarcopenia consensus was a simple and useful tool to predict mortality in chronic hemodialysis patients. Furthermore, GNRI assessment can be a useful tool for screening before assessing possible sarcopenia when it is difficult to perform SARC-F to all patients.


2019 ◽  
Vol 26 (11) ◽  
pp. 1-12 ◽  
Author(s):  
Carine Lumi ◽  
Fabrício Edler Macagnan ◽  
Adriana Kessler ◽  
Priscila De Toni ◽  
Adriana Maisonnave Raffone

Background/Aims The negative impact caused by haematopoietic stem cell transplantation still requires further investigation. This study aims to investigate the effects of this procedure on skeletal muscle strength, functional performance and fatigue sensation in the hospitalisation phase. Methods This prospective cohort study aimed to assess physical performance by measuring ventilatory muscle strength, peripheral muscle strength and fatigue in patients who underwent haematopoietic stem cell transplantation. Results The sample consisted of 30 patients of both sexes (63% men) with a mean age of 48.6 ± 13.2 years. Maximal inspiratory pressure and expiratory pressure decreased by 19% and 16%, respectively (P<0.001). There was a 16% reduction in handgrip strength in the second assessment (P<0.001), as well as a reduction of 30.6% in the 30-Second Chair Stand Test (P<0.001). The fatigue test score increased exponentially (60%) (P<0.001). Individuals with worse results in the 30-Second Chair Stand Test remained hospitalised for a longer period than those with better results (P=0.024). Conclusions This study concluded that after the transplantation of haematopoietic stem cells there was a relevant reduction in the results of the applied tests, as well as an increase in fatigue.


2021 ◽  
Vol 10 (17) ◽  
pp. e139101724018
Author(s):  
Nathalie de Almeida Silva ◽  
Cledinaldo Lira Júnior ◽  
Maria Goretti da Cunha Lisboa ◽  
Jozilma de Medeiros Gonzaga ◽  
Danilo de Almeida Vasconcelos ◽  
...  

Objective. To verify the correlation between muscle mass and neuromuscular function in muscle strength of women practicing and not practicing physical activities. Methods. This is a cross-sectional study conducted with older women (60 and over), physically active (fa) and physically inactive (fi). The muscle strength of the upper limb (handgrip strength - hgs; resisfor test) and lower limb (30 second chair stand test) were evaluated; as well as muscle mass (calf circumference - cc); and neuromuscular activity (semg) of the following muscles: flexor carpi radialis (fcr) and biceps brachii (bb) (upper limb); vastus lateralis (vl), vastus medialis (vm) and tibialis anterior (ta) (lower limb). The student t test and multiple linear regression were used (95%; p <.05). Results. Overall, 59 women were evaluated (71.5 ± 7.1 years), 31 fa and 28 fi. Fa women had significantly better values ​​in dynamic muscular strength tests of the upper (p=.001) and lower limbs (p<.0001). There was no significant difference in muscle mass between groups. After adjustment for covariates, there was relationship between cc and activity of fcr muscle with hgs (r2adj.= 0.64), and cc with the 30 second chair stand test (r2adj.= .39) in fa women. Among fi women, there was significant correlation between activity of fcr muscle and hgs (r2adj.= .35) and cc and neural activity of fcr with resisfor (r2adj.= .66). Conclusion. Physical exercise was related to higher dynamic muscle strength. Differences in the relationship between muscle mass and neuromuscular activity with strength in each test indicate physiological differences for each strength exercise applied.


Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 547 ◽  
Author(s):  
Julia Traub ◽  
Ina Bergheim ◽  
Martin Eibisberger ◽  
Vanessa Stadlbauer

The European Working group on Sarcopenia in Older People recently updated the diagnostic criteria for sarcopenia. It is yet unclear how these modified criteria influence the rate of diagnosis in high risk populations, such as liver cirrhosis. We therefore assessed if the new diagnostic criteria for sarcopenia impacts on sarcopenia prevalence in liver cirrhosis. Within two years 114 cirrhotic patients were prospectively enrolled in the study. Sarcopenia was determined by muscle strength (handgrip strength), muscle mass (lumbal muscle index) and muscle performance (gait speed). Using the 2019 definition, the rate of pre-sarcopenia was significantly lower (30.7% versus 3.5%) due to the different starting points (2010 muscle mass, 2019 muscle strength) and cut-off values (muscle strength). The change in diagnostic criteria for sarcopenia drastically influences the rate of pre-sarcopenia diagnosis in cirrhotics. To evaluate, which diagnostic criteria should be chosen to diagnose sarcopenia in liver cirrhosis patients, prospective studies are needed.


2020 ◽  
Vol 6 (2) ◽  
pp. 364-374
Author(s):  
Mustika Fitri ◽  
Upik Rahmi ◽  
Pipit Pitriani ◽  
Afianti Sulastri

Aktivitas fisik akan meningkatkan kebugaran jasmani sehingga dapat memperlambat perkembangan kognitif dan penurunan fisik lansia dengan demensia. Demensia merupakan sindrom neurodegeneratif yang timbul karena adanya kelainan bersifat kronis dan progesif disertai dengan gangguan fungsi luhur multipel seperti kalkulasi, kapasitas belajar, bahasa, dan mengambil keputusan. Penelitian ini bertujuan untuk mengetahui kebugaran jasmani lansia dengan demensia pasca aktivitas fisik dengan senam vitalisasi otak. Metode yang digunakan dalam penelitian ini yaitu Metode Experimental. 10 subjek yang berusia 60 – 85 tahun dengan demensia ringan diberi perlakuan senam vitalisasi otak selama 12 kali dengan durasi waktu 25 menit. Setelah melakukan aktivitas fisik dilakukan pemeriksaan tes kebugaran jasmani (testing the elderly) yang terdiri dari: 6 minutes walk test (6 MWT), flexibility: Chair seat and reach test (CSRT), Muscle strength and endurance: Chair stand test (CST), dan Arm curl test (ACT), koordinasi dan kelincahan, 8 Foot up and go test (8 FUGT). Hasil penelitian dengan menggunakan uji T menunjukkan bahwa tes kebugaran memberikan hasil yang signifikan pada tes CST, CSRT (p value 0,0296) dan 8 FUGT 6MWT (pvalue 0,0229) pada tingkat kepercayaan 95%.  Kesimpulannya, aktivitas fisik vitalisasi otak berpengaruh terhadap kebugaran jasmani dengan perbaikan tonus otot dan kognitif pada lansia dengan demensia.


2021 ◽  
Author(s):  
Merve Eylul Acar ◽  
Deniz Bayraktar ◽  
Sercan Gucenmez ◽  
Devrim Can Sarac ◽  
Nurullah Buker ◽  
...  

ABSTRACT Objectives No studies examined the lower extremity–related anaerobic exercise capacity or functional status in adult patients with FMF. Methods Twenty-four patients with FMF (12 males) and 24 age–sex-matched healthy controls (13 males) were included in the study. Lower extremity–related anaerobic exercise capacity was assessed by using Wingate Anaerobic Test. Lower extremity–related functional status was examined by using 9-Step Stair Climb Test, 10-Repetition Chair Stand Test, and Six-Minute Walking Distance. Muscle strength of hip flexors, hip extensors, knee flexors, and knee extensors were evaluated by using a hand-held dynamometer. Results Patients with FMF had significantly poorer results in all anaerobic exercise capacity parameters and functional status assessments (P &lt; 0.05), except muscle strength measurements (P &gt; 0.05). Both average and peak anaerobic exercise capacities correlated significantly with all muscle strength measurements, 9-Step Stair Climb Test, 10-Repetition Chair Stand Test times, and Six-Minute Walk Distances (P &lt; 0.05) in patients with FMF. Conclusion Lower extremity–related anaerobic exercise capacity and functional status seem to be diminished in adult patients with FMF. Evaluating these parameters may be beneficial for planning more appropriate and individualized treatment regimens such as patient education and exercise counselling for patients with FMF.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shuji Sawada ◽  
Hayao Ozaki ◽  
Toshiharu Natsume ◽  
Pengyu Deng ◽  
Toshinori Yoshihara ◽  
...  

Abstract Background Low muscle strength has been focused on as an essential characteristic of sarcopenia, and the 30-s chair stand test (CS-30) could be a particularly useful test for assessing muscle strength. While it is speculated to be a beneficial tool for the assessment of sarcopenia, this remains to be verified. In this study, we examined the reliability and optimal diagnostic score of the CS-30 for assessing sarcopenia in elderly Japanese participants. Methods This cross-sectional study included 678 participants (443 females and 235 males) who underwent the test for sarcopenia as per the Asian Working Group for Sarcopenia (AWGS) 2019, the CS-30 test, and the isometric knee-extension muscle strength test. ROC analysis was used to estimate the optimal CS-30 scores at which sarcopenia was detected. Results CS-30 scores were positively associated with sarcopenia (OR: 0.88; 95% CI:0.82–0.93). The AUC of the CS-30 for sarcopenia definition were 0.84 (p < 0.001) for females and 0.80 (p < 0.001) for males. The optimal number of stands in the CS-30 that predicted sarcopenia was 15 for females (sensitivity, 76.4%; specificity, 76.8%) and 17 for males (sensitivity, 75.0%; specificity, 71.7%). Conclusions The CS-30 was found to be a reliable test for sarcopenia screening in the elderly Japanese population.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Theng Choon Ooi ◽  
Devinder Kaur Ajit Singh ◽  
Suzana Shahar ◽  
Nor Fadilah Rajab ◽  
Divya Vanoh ◽  
...  

Abstract Background Falls incidence rate and comprehensive data on factors that predict occasional and repeated falls from large population-based studies are scarce. In this study, we aimed to determine the incidence of falls and identify predictors of occasional and recurrent falls. This was done in the social, medical, physical, nutritional, biochemical, cognitive dimensions among community-dwelling older Malaysians. Methods Data from 1,763 Malaysian community-dwelling older persons aged ≥ 60 years were obtained from the LRGS-TUA longitudinal study. Participants were categorized into three groups according to the presence of a single fall (occasional fallers), ≥two falls (recurrent fallers), or absence of falls (non-fallers) at an 18-month follow-up. Results Three hundred and nine (17.53 %) participants reported fall occurrences at an 18-month follow-up, of whom 85 (27.51 %) had two or more falls. The incidence rate for occasional and recurrent falls was 8.47 and 3.21 per 100 person-years, respectively. Following multifactorial adjustments, being female (OR: 1.57; 95 % CI: 1.04–2.36), being single (OR: 5.31; 95 % CI: 3.36–37.48), having history of fall (OR: 1.86; 95 % CI: 1.19–2.92) higher depression scale score (OR: 1.10; 95 % CI: 1.02–1.20), lower hemoglobin levels (OR: 0.90; 95 % CI: 0.81-1.00) and lower chair stand test score (OR: 0.93; 95 % CI: 0.87-1.00) remained independent predictors of occasional falls. While, having history of falls (OR: 2.74; 95 % CI: 1.45–5.19), being a stroke survivor (OR: 8.57; 95 % CI: 2.12–34.65), higher percentage of body fat (OR: 1.04; 95 % CI: 1.01–1.08) and lower chair stand test score (OR: 0.87; 95 % CI: 0.77–0.97) appeared as recurrent falls predictors. Conclusions Having history of falls and lower muscle strength were predictors for both occasional and recurrent falls among Malaysian community-dwelling older persons. Modifying these predictors may be beneficial in falls prevention and management strategies among older persons.


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