This chapter describes music therapy in cancer care in Western and Asian countries. Detailed descriptions of cancer prevalence, mortality rates, histological classifications, treatments, and biopsychosocial effects are provided. When affected by cancer, music therapy can offer support, enable symptom alleviation, promote endurance and spiritual well-being, and assist in functional restoration and quality of life improvement. An evolving music therapy assessment procedure in oncology is outlined as well as common music therapy methods used in inpatient and outpatient settings, and to promote community ward-based care. Music therapists can: Replay music from the patients’ and families’ lives; help them to explore new musical experiences, such as improvisation, song writing, chanting and toning; and offer music relaxation and supportive or guided imagery experiences. Research has demonstrated music therapy’s positive effects on patients, their families, and staff care givers, reinforcing its important and meaningful role in multidisciplinary oncology care.