scholarly journals Adolescent and young adult neuro-oncology: a comprehensive review

2021 ◽  
Author(s):  
Kee Kiat Yeo ◽  
Darcy E Burgers ◽  
Katelynn Brodigan ◽  
Karen Fasciano ◽  
A Lindsay Frazier ◽  
...  
Keyword(s):  
Young Adult ◽  
Reproductive Health ◽  
Tumor Biology ◽  
Psychosocial Care ◽  
Health Needs ◽  
Adolescent And Young Adult ◽  
Molecular Testing ◽  
Psychosocial Needs ◽  
Clinical Trials Enrollment ◽  
Diagnostic Work

Abstract Adolescent and young adult (AYA; ages 15-39) patients represent a population that experiences significant challenges in cancer care and research, exemplified by poorer clinical outcomes as well as unmet psychosocial and reproductive health needs. Despite central nervous system (CNS) tumors being one of the most common malignancies diagnosed in the age group, there is a clear paucity of AYA CNS tumor-specific publications, especially those related to the unique psychosocial and reproductive health needs of this population of patients. In this review, we examine various aspects of AYA oncological care including tumor biology, clinical outcome, clinical trials enrollment rate, site of care, unique psychosocial needs, and oncofertility. We assess the current state of these issues, highlight areas of deficiencies, and outline the steps needed to address these concerns. We emphasize the importance of comprehensive molecular testing as part of the diagnostic work-up, expansion of clinical trial availability, access to psychosocial care and oncofertility expertise, and the development of AYA-specific clinical research to define best practices and advancing care for this population.

scholarly journals Reproductive health needs of adolescent and young adult women with pediatric rheumatic diseases

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Kristine Carandang ◽  
Veronica Mruk ◽  
Stacy P. Ardoin ◽  
Brittany Huynh ◽  
Megan E. B. Clowse ◽  
...  
Keyword(s):  
Young Adult ◽  
Reproductive Health ◽  
Rheumatic Diseases ◽  
Health Needs ◽  
Adolescent And Young Adult ◽  
Adult Women ◽  
Young Adult Women

scholarly journals Male Reproductive Health After Childhood, Adolescent, and Young Adult Cancers: A Report From the Children's Oncology Group

2012 ◽  
Vol 30 (27) ◽  
pp. 3408-3416 ◽  
Author(s):  
Lisa B. Kenney ◽  
Laurie E. Cohen ◽  
Margarett Shnorhavorian ◽  
Monika L. Metzger ◽  
Barbara Lockart ◽  
...  
Keyword(s):  
Young Adult ◽  
Reproductive Health ◽  
Task Force ◽  
Young Male ◽  
Adolescent And Young Adult ◽  
Male Survivors ◽  
Male Health ◽  
Follow Up Care

The majority of children, adolescents, and young adults diagnosed with cancer will become long-term survivors. Although cancer therapy is associated with many adverse effects, one of the primary concerns of young male cancer survivors is reproductive health. Future fertility is often the focus of concern; however, it must be recognized that all aspects of male health, including pubertal development, testosterone production, and sexual function, can be impaired by cancer therapy. Although pretreatment strategies to preserve reproductive health have been beneficial to some male patients, many survivors remain at risk for long-term reproductive complications. Understanding risk factors and monitoring the reproductive health of young male survivors are important aspects of follow-up care. The Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancer (COG-LTFU Guidelines) were created by the COG to provide recommendations for follow-up care of survivors at risk for long-term complications. The male health task force of the COG-LTFU Guidelines, composed of pediatric oncologists, endocrinologists, nurse practitioners, a urologist, and a radiation oncologist, is responsible for updating the COG-LTFU Guidelines every 2 years based on literature review and expert consensus. This review summarizes current task force recommendations for the assessment and management of male reproductive complications after treatment for childhood, adolescent, and young adult cancers. Issues related to male health that are being investigated, but currently not included in the COG-LTFU Guidelines, are also discussed. Ongoing investigation will inform future COG-LTFU Guideline recommendations for follow-up care to improve health and quality of life for male survivors.

scholarly journals Female Reproductive Health After Childhood, Adolescent, and Young Adult Cancers: Guidelines for the Assessment and Management of Female Reproductive Complications

2013 ◽  
Vol 31 (9) ◽  
pp. 1239-1247 ◽  
Author(s):  
Monika L. Metzger ◽  
Lillian R. Meacham ◽  
Briana Patterson ◽  
Jacqueline S. Casillas ◽  
Louis S. Constine ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young Adult ◽  
Reproductive Health ◽  
Hormonal Regulation ◽  
Pubertal Development ◽  
Adolescent And Young Adult ◽  
Primary Therapy ◽  
Ongoing Research

Purpose As more young female patients with cancer survive their primary disease, concerns about reproductive health related to primary therapy gain relevance. Cancer therapy can often affect reproductive organs, leading to impaired pubertal development, hormonal regulation, fertility, and sexual function, affecting quality of life. Methods The Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancer (COG-LTFU Guidelines) are evidence-based recommendations for screening and management of late effects of therapeutic exposures. The guidelines are updated every 2 years by a multidisciplinary panel based on current literature review and expert consensus. Results This review summarizes the current task force recommendations for the assessment and management of female reproductive complications after treatment for childhood, adolescent, and young adult cancers. Experimental pretreatment as well as post-treatment fertility preservation strategies, including barriers and ethical considerations, which are not included in the COG-LTFU Guidelines, are also discussed. Conclusion Ongoing research will continue to inform COG-LTFU Guideline recommendations for follow-up care of female survivors of childhood cancer to improve their health and quality of life.

scholarly journals The importance of assessing priorities of reproductive health concerns among adolescent and young adult patients with cancer

Cancer ◽  
2015 ◽  
Vol 121 (15) ◽  
pp. 2529-2536 ◽  
Author(s):  
Devin Murphy ◽  
James L. Klosky ◽  
Damon R. Reed ◽  
Amanda M. Termuhlen ◽  
Susan V. Shannon ◽  
...  
Keyword(s):  
Young Adult ◽  
Reproductive Health ◽  
Adult Patients ◽  
Adolescent And Young Adult ◽  
Health Concerns ◽  
Patients With Cancer

scholarly journals 239. Key Stakeholder’s Perspectives On Adolescent And Young Adult Reproductive Health In Rural Latino Communities

2019 ◽  
Vol 64 (2) ◽  
pp. S122
Author(s):  
Rachel Hildebrand ◽  
Romina L. Barral ◽  
Astrid Guerrero Avitia ◽  
Mariana Ramirez ◽  
Maria Trent ◽  
...  
Keyword(s):  
Young Adult ◽  
Reproductive Health ◽  
Adolescent And Young Adult ◽  
Latino Communities

Disparities between provider assessment and documentation of care needs in the care of adolescent and young adult patients with sarcoma.

2020 ◽  
Vol 38 (29_suppl) ◽  
pp. 218-218
Author(s):  
Grace Eileen McKay ◽  
Amanda Marie Parkes
Keyword(s):  
Young Adult ◽  
Chart Review ◽  
Retrospective Chart Review ◽  
Developmental Time ◽  
Adolescent And Young Adult ◽  
Psychosocial Needs ◽  
Care Needs ◽  
Improvement Project ◽  
Oncology Practice ◽  
Oncology Providers

218 Background: Given the occurrence of cancer during a complex developmental time, adolescent and young adult (AYA) patients have unique psychosocial needs, necessitating supportive care guidelines including National Comprehensive Cancer Network (NCCN) AYA guidelines. We sought to assess compliance with NCCN AYA guidelines and compare to oncology provider identified AYA care needs. Methods: Retrospective chart review was performed on AYA patients (15-39 years) with sarcoma seen at least once in 2019 at the University of Wisconsin (UW), identifying documentation of discussions deemed critical per NCCN AYA guidelines. As per ASCO’s Quality Oncology Practice Initiative certification, we considered a threshold of 75% or higher to be compliant. Compliance was compared with an electronic survey of UW oncology providers regarding AYA patient needs, with items determined to have adequate resources if noted sufficient by >75% of providers. Results: We identified 43 AYA patients with sarcoma. As seen in table, <75% of patients had documentation regarding contraception, fertility, finances, genetics, social work referral and clinical trials indicating non-compliance. Surveys, completed by 38 oncology providers, showed significant discordance between provider’s perception of adequate access to resources and compliance on chart review. Conclusions: Disparities between oncology provider assessment of AYA care needs and lack of documentation of critical components of AYA patient care demonstrates the need for novel tools to evaluate AYA care needs beyond provider assessments. Care needs identified in our study will serve as the basis of an ongoing quality improvement project to better support AYA patients at UW. [Table: see text]

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