The organization and structure of autobiographical memory

2019 ◽  
Keyword(s):  
Autobiographical Memory ◽  
Basic Structure ◽  
Human Memory ◽  
Memory Organization ◽  
Memory Research ◽  
Reminiscence Bump ◽  
The Past ◽  
Functional Perspective ◽  
And Function

The topic of autobiographical memory has held a prominent role in memory research for the past 30 years, as it has proven indispensable to the understanding of human memory and cognition. An important focus of autobiographical memory research is uncovering the basic structure, nature, and organization of the autobiographical memory system. This edited volume addresses the organization and structure of autobiographical memory. Based on over 30 years of research, and the latest empirical findings, this volume presents the major theories and problems in the science of autobiographical memory organization. At its core are two influential global views on the organization, structure, and function of autobiographical memory (chapters 2 and 3). In addition, the volume examines the organization of autobiographical memory from a developmental perspective (chapter 4), a chapter examining the neuroscience of autobiographical memory organization (chapter 7), and a chapter examining organization from a functional perspective (chapter 6). Also covered is the role of culture in forming autobiographical memory (chapter 5), the role of the self in organizing autobiographical memory (chapter 8), insights from the reminiscence bump on organization (chapter 9), and a chapter on the organization of episodic autobiographical memories (chapter 10).

The Role of the Self in the Organization of Memories and Imagined Future Events

2019 ◽  
pp. 134-159
Author(s):  
Alexandra Ernst ◽  
Clare J. Rathbone
Keyword(s):  
Autobiographical Memory ◽  
The Self ◽  
Healthy Controls ◽  
Future Thinking ◽  
Reminiscence Bump ◽  
The Past ◽  
Future Events ◽  
Self Reference ◽  
Neuropsychiatric Conditions

This chapter reviews the organizational role of the self in the distributions and accessibility of memories and imagined future events. It covers research on the self-reference effect, self-defining memories, and the reminiscence bump. In this context, the different methods used to explore the relationships between the self, autobiographical memory, and future thinking are reviewed. A comparative view of the findings obtained for the past and the future are also given. The contributions of studies conducted in both healthy controls and clinical populations are discussed. One section is devoted to investigations in people with neurological and neuropsychiatric conditions and their contribution to improving our understanding of the relationships between autobiographical memory and the self.

scholarly journals Immunosuppressive Mechanisms of Regulatory B Cells

2021 ◽  
Vol 12 ◽  
Author(s):  
Diego Catalán ◽  
Miguel Andrés Mansilla ◽  
Ashley Ferrier ◽  
Lilian Soto ◽  
Kristine Oleinika ◽  
...  
Keyword(s):  
B Cells ◽  
Immune Responses ◽  
Metabolic Diseases ◽  
Inflammatory Responses ◽  
Surface Proteins ◽  
Regulatory B Cells ◽  
Cell Surface Proteins ◽  
The Past ◽  
And Function

Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing immune responses and reestablishing immune homeostasis. The important role of Bregs in restraining the pathology associated with exacerbated inflammatory responses in autoimmunity and graft rejection has been consistently demonstrated, while more recent studies have suggested a role for this population in other immune-related conditions, such as infections, allergy, cancer, and chronic metabolic diseases. Initial studies identified IL-10 as the hallmark of Breg function; nevertheless, the past decade has seen the discovery of other molecules utilized by human and murine B cells to regulate immune responses. This new arsenal includes other anti-inflammatory cytokines such IL-35 and TGF-β, as well as cell surface proteins like CD1d and PD-L1. In this review, we examine the main suppressive mechanisms employed by these novel Breg populations. We also discuss recent evidence that helps to unravel previously unknown aspects of the phenotype, development, activation, and function of IL-10-producing Bregs, incorporating an overview on those questions that remain obscure.

Judicializing Religion

2020 ◽  
pp. 157-188
Author(s):  
Yvonne Tew
Keyword(s):  
Religious Freedom ◽  
Freedom Of Expression ◽  
Basic Structure ◽  
Constitutional Rights ◽  
Quarter Century ◽  
The Past ◽  
Malaysian Politics ◽  
Role Of Religion ◽  
Civil Courts

Religion has become one of the great fault lines of modern Malaysian politics and adjudication. This chapter focuses on the role of religion and religious freedom in the contemporary Malaysian state. It outlines the constitution-making process to locate the place of Islam and religious liberty within the Constitution’s generally secular original framework. Over the past quarter century, the politicization and judicialization of religion has led to an expansion of Islam’s role, fueling polarizing debate over the Malaysian state’s identity as secular or Islamic. Courts have contributed to elevating Islam’s position by deferring jurisdiction to the Sharia courts and expansively interpreting Islam’s constitutional position. The chapter then turns from the descriptive to the prescriptive. It discusses how courts can draw on the constitutional basic structure doctrine to entrench the judicial power of the civil courts to reclaim jurisdictional areas that engage constitutional rights which in the past they have ceded to the religious courts, such as apostasy. It also outlines how courts can use a purposive interpretive approach in line with the Constitution’s framework of protection for religious minorities and individual rights. Finally, it shows how the court can operationalize a proportionality analysis to closely scrutinize government regulations that restrict religious freedom or freedom of expression.

A Scene-Based Episodic Memory System for a Simulated Autonomous Creature

2013 ◽  
Vol 4 (1) ◽  
pp. 32-64 ◽  
Author(s):  
Elisa C. Castro ◽  
Ricardo R. Gudwin
Keyword(s):  
Episodic Memory ◽  
Navigation System ◽  
Cognitive Architecture ◽  
Human Memory ◽  
Memory Systems ◽  
Memory Module ◽  
The Past ◽  
3D Environment ◽  
Main Ideas

In this paper the authors present the development of a scene-based episodic memory module for the cognitive architecture controlling an autonomous virtual creature, in a simulated 3D environment. The scene-based episodic memory has the role of improving the creature’s navigation system, by evoking the objects to be considered in planning, according to episodic remembrance of earlier scenes testified by the creature where these objects were present in the past. They introduce the main background on human memory systems and episodic memory study, and provide the main ideas behind the experiment.

Role of PET in Diagnosis and Risk Assessment in Patients with Known or Suspected CAD

2015 ◽  
Author(s):  
Brian A. Mc Ardle ◽  
Jennifer M. Renaud ◽  
Robert A. deKemp ◽  
Rob S. B. Beanlands
Keyword(s):  
Myocardial Perfusion ◽  
Diagnostic Accuracy ◽  
Lower Cost ◽  
Image Artifacts ◽  
Cardiac Pet ◽  
The Past ◽  
Pet Myocardial Perfusion Imaging ◽  
Patient Radiation Exposure ◽  
And Function

Cardiac PET enables evaluation of multiple aspects of myocardial perfusion, metabolism, cell signaling and function that are of value both for diagnosis and prognostication in patients with known or suspected CAD and its use has increased in the past three decades. PET myocardial perfusion imaging (MPI) offers several technological advantages over SPECT including; higher photon energy, higher count sensitivity, more consistent attenuation correction and the ability to measure myocardial blood flow in absolute terms. These result in faster imaging times, lower patient radiation exposure and increased diagnostic accuracy. However the availability of PET MPI remains limited, predominantly due to expense. Efforts are underway to expand the use of PET MPI beyond larger centers, with lower-cost scanners and more widely available radiotracers. In this chapter we describe the latest advances in PET camera technology and image reconstruction as well as potential image artifacts specific to PET MPI. We go on to discuss diagnostic accuracy and prognostic value of PET MPI as well as its role in clinical practice.

scholarly journals Endocrine Significance of SARS-CoV-2’s Reliance on ACE2

Endocrinology ◽  
2020 ◽  
Vol 161 (9) ◽  
Author(s):  
Eric Lazartigues ◽  
Mirza Muhammad Fahd Qadir ◽  
Franck Mauvais-Jarvis
Keyword(s):  
Potential Role ◽  
Renin Angiotensin System ◽  
Converting Enzyme ◽  
Angiotensin System ◽  
Angiotensin Converting Enzyme 2 ◽  
Global Impact ◽  
The Past ◽  
And Function ◽  
Endocrine Tissues

Abstract The current COVID-19 pandemic is the most disruptive event in the past 50 years, with a global impact on health care and world economies. It is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a coronavirus that uses angiotensin-converting enzyme 2 (ACE2) as an entry point to the cells. ACE2 is a transmembrane carboxypeptidase and member of the renin-angiotensin system. This mini-review summarizes the main findings regarding ACE2 expression and function in endocrine tissues. We discuss rapidly evolving knowledge on the potential role of ACE2 and SARS coronaviruses in endocrinology and the development of diabetes mellitus, hypogonadism, and pituitary and thyroid diseases.

Indigenous approaches to the past: ‘Creative histories’ at the Hyde Park Barracks, Sydney

2020 ◽  
Vol 9 (1) ◽  
pp. 83-102 ◽  
Author(s):  
Kiera Lindsey
Keyword(s):  
Visual Art ◽  
The Other ◽  
Cultural Relations ◽  
Form And Function ◽  
The Past ◽  
Cultural Responses ◽  
And Function ◽  
The Way

This article discusses a recent art project created by the Wiradjuri and Kamilaroi artist Jonathon Jones, which was commissioned to commemorate the opening of the revitalized Hyde Park Barracks in Sydney in early 2020. Jones’ work involves a dramatic installation of red and white crushed stones laid throughout the grounds of the barracks, merging the image of the emu footprint with that of the English broad convict arrow to ‘consider Australia’s layered history and contemporary cultural relations’. This work was accompanied by a ‘specially-curated programme’ of performances, workshops, storytelling and Artist Talks. Together, these elements were designed to unpack how certain ‘stories determine the ways we came together as a nation’. As one of the speakers of the Artist Talk’s programme, I had a unique opportunity to experiment with what colleagues and I have been calling ‘Creative histories’ in reference to the way some artists and historians are choosing to communicate their research about the past in ways that experiment with form and function and push disciplinary or generic boundaries. This article reflects upon how these two distinct creative history projects – one visual art, the other performative – renegotiate the complex and contested pasts of the Hyde Park Barracks. I suggest that both examples speak to the role of memory and creativity in shaping cultural responses to Australia’s colonial past, while Jones' programme illustrates how Indigenous artists and academics are making a profound intervention into contemporary understandings of how history is ‘done’ in Australia.

scholarly journals The Future of International Legal Scholarship: Some Thoughts on ‘Practice’, ‘Growth’, and ‘Dissemination’

2013 ◽  
Vol 27 (1) ◽  
pp. 1-10 ◽  
Author(s):  
CARSTEN STAHN ◽  
ERIC DE BRABANDERE
Keyword(s):  
International Law ◽  
Legal Discourse ◽  
Legal Scholarship ◽  
Self Reflection ◽  
The Past ◽  
Niche Area ◽  
And Function ◽  
Changing Role ◽  
Role And Function

Like international legal scholarship, LJIL is in transition. Our colleagues, Larissa van den Herik and Jean d'Aspremont, who have shaped much of the role and plural identity of the journal over the past decade, in collaboration with our different sections, have passed leadership on to us, the new team of (co-)editors-in-chief. This editorial reflects on the changing role and function of scholarship in international law, a theme important to our predecessors and ourselves. This is to some extent a niche area. It has not received much attention in discourse. With some notable exceptions, legal journals are typically reluctant to address overarching meta-issues of discourse, i.e. issues of production of scholarship, the role of journals vis-à-vis other media, or the broader direction of the development of international legal scholarship. Such issues might be perceived as non-scientific by some. We feel that it is important to include such dimensions, including critical self-reflection on our discipline, in international legal discourse.

scholarly journals The Role of Biological Significance in Human Learning and Memory

2019 ◽  
Vol 32 ◽  
Author(s):  
Benjamin M. Seitz ◽  
Aaron P. Blaisdell ◽  
Cody W. Polack ◽  
Ralph R. Miller
Keyword(s):  
Human Evolution ◽  
Evolutionary History ◽  
Prior Experience ◽  
Biological Significance ◽  
Human Memory ◽  
Memory Systems ◽  
Human Learning ◽  
Memory Research ◽  
History Of

Deeply rooted within the history of experimental psychology is the search for general laws of learning that hold across tasks and species. Central to this enterprise has been the notion of equipotentiality; that any two events have the same likelihood of being associated with one another as any other pair of events. Much work, generally summarized as ‘biological constraints on learning,’ has challenged this view, and demonstrates pre-existing relations between cues and outcomes, based on genes and prior experience, that influence potential associability. Learning theorists and comparative psychologists have thus recognized the need to consider how the evolutionary history as well as prior experience of the organism being studied influences its ability to learn about and navigate its environment. We suggest that current models of human memory, and human memory research in general, lack sufficient consideration of how human evolution has shaped human memory systems. We review several findings that suggest the human memory system preferentially processes information relevant to biological fitness, and highlight potential theoretical and applied benefits afforded by adopting this functionalist perspective.

scholarly journals Constructive memory: past and future

2012 ◽  
Vol 14 (1) ◽  
pp. 7-18 ◽  
Keyword(s):  
Cognitive Processes ◽  
Functional Neuroimaging ◽  
False Memories ◽  
Human Memory ◽  
Memory System ◽  
Relevant Research ◽  
The Past ◽  
Future Events ◽  
Neuroimaging Techniques

Human memory is not a literal reproduction of the past, but instead relies on constructive processes that are sometimes prone to error and distortion. Understanding of constructive memory has accelerated during recent years as a result of research that has linked together its cognitive and neural bases. This article focuses on three aspects of constructive memory that have been the target of recent research: (i) the idea that certain kinds of memory distortions reflect the operation of adaptive cognitive processes that contribute to the efficient functioning of memory; (ii) the role of a constructive memory system in imagining or simulating possible future events; and (iii) differences between true and false memories that have been revealed by functional neuroimaging techniques. The article delineates the theoretical implications of relevant research, and also considers some clinical and applied implications.

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