M196. CLINICAL CORRELATES OF SUBJECTIVE QUALITY OF LIFE IN ADULT PATIENTS WITH EARLY PSYCHOSIS IN HONG KONG

Abstract Background Subjective quality of life (SQoL) is an important outcome domain in patients with early psychosis. In an attempt to better understand and maximize SQoL of early psychosis patients, an increasing number of research has been conducted to investigate factors associated with SQoL. Nonetheless, most previous studies focused on younger patients with early psychosis. In this study, the correlates of SQoL in adult patients who had completed 3-year specialized early intervention service for first-episode psychosis (FEP) in Hong Kong were investigated. Methods In total, one hundred and one Chinese patients aged 26–55 years who completed 3-year specialized early intervention service for psychosis in Hong Kong were recruited. Assessments on illness onset (DUP), clinical (PANSS, BNSS, SUMD), intrinsic motivation (by items in Quality of Life Scale, QLS), functional (SOFAS), antipsychotic-induced parkinsonism features (Simpson-Angus Scale, SAS) were conducted. SQoL was evaluated by Chinese version SF-12 which consist of physical and mental components for analysis. Results Correlation analyses showed that SF12 physical health score was correlated with PANSS depression component (p<0.001), QLS intrinsic motivation score (p=0.001) and SAS score (p<0.05) while SF12 mental health score was correlated with PANSS depression score (p<0.001), QLS intrinsic motivation score (p<0.05) and SAS score (p<0.05). Multiple linear regression analyses further revealed that lower PANSS depression score (p<0.001) and higher intrinsic motivation (measured by QLS, p<0.05) were independently associated with better physical SQoL, while lower PANSS depression score (p<0.001) and lower SAS side-effect score (p<0.05) were independently related to better mental SQoL. Discussion Our results are consistent with the literature which indicates that SQoL is significantly related to depressive symptoms. In addition, patients with higher intrinsic motivation and less antipsychotic-induced extrapyramidal side-effect have better SQoL. Further analysis on the longitudinal data will clarify variables predictive of SQoL at follow-up.

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Cost-effectiveness of an early intervention service for people with psychosis

The British Journal of Psychiatry ◽

10.1192/bjp.bp.109.065896 ◽

2010 ◽

Vol 196 (5) ◽

pp. 377-382 ◽

Cited By ~ 103

Author(s):

Paul McCrone ◽

Tom K. J. Craig ◽

Paddy Power ◽

Philippa A. Garety

Keyword(s):

Quality Of Life ◽

Early Intervention ◽

Cost Effectiveness ◽

Standard Care ◽

Intervention Group ◽

Cost Effective ◽

Care Group ◽

Early Intervention Service ◽

Intervention Service

BackgroundThere is concern that delaying treatment for psychosis may have a negative impact on its long-term course. A number of countries have developed early intervention teams but there is limited evidence regarding their cost-effectiveness.AimsTo compare the costs and cost-effectiveness of an early intervention service in London with standard care.MethodIndividuals in their first episode of psychosis (or those who had previously discontinued treatment) were recruited to the study. Clinical variables and costs were measured at baseline and then at 6- and 18-month follow-up. Information on quality of life and vocational outcomes were combined with costs to assess cost-effectiveness.ResultsA total of 144 people were randomised. Total mean costs were £11 685 in the early intervention group and £14 062 in the standard care group, with the difference not being significant (95% CI –£8128 to £3326). When costs were combined with improved vocational and quality of life outcomes it was shown that early intervention would have a very high likelihood of being cost-effective.ConclusionsEarly intervention did not increase costs and was highly likely to be cost-effective when compared with standard care.

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Subjective quality of life and its predictors among people with early psychosis in central Vietnam: a short-term longitudinal study

International Journal of Culture and Mental Health ◽

10.1080/17542863.2017.1397720 ◽

2017 ◽

Vol 11 (4) ◽

pp. 373-388 ◽

Cited By ~ 1

Author(s):

Seiji Humphries ◽

Robert King ◽

Michael P Dunne ◽

Cat Huu Nguyen

Keyword(s):

Quality Of Life ◽

Longitudinal Study ◽

Subjective Quality ◽

Early Psychosis ◽

Subjective Quality Of Life ◽

Short Term ◽

Central Vietnam

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Stress, Health-Related Behavior and Quality of Life on Depressive Symptomatology in a Sample of Adolescents

Psychological Reports ◽

10.2466/pr0.1992.71.1.183 ◽

1992 ◽

Vol 71 (1) ◽

pp. 183-186 ◽

Cited By ~ 18

Author(s):

Wesley E. Hawkins ◽

Michele J. Hawkins ◽

John Seeley

Keyword(s):

Quality Of Life ◽

At Risk ◽

Problem Behaviors ◽

Life Stress ◽

Depressive Symptomatology ◽

Function Analysis ◽

Depression Score ◽

Low Risk ◽

Subjective Quality Of Life

This study examined the correlations of 21 variables categorized into sociodemographic, subjective quality of life, stress, problem behavior, and health behavior predictors of at-risk and low-risk depressive symptomatology for a sample of 1056 adolescents attending public school. Discriminant function analysis showed lower life satisfaction, higher stress, and perceived unattractiveness as major discriminating variables for at-risk (CES-Depression score >23) versus low-risk depressed adolescents. Only two problem behaviors were significant, smoking for girls and hard drug use for boys.

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Subjective quality of life in outpatients with schizophrenia in Hong Kong and Beijing: relationship to socio-demographic and clinical factors

Quality of Life Research ◽

10.1007/s11136-007-9285-2 ◽

2007 ◽

Vol 17 (1) ◽

pp. 27-36 ◽

Cited By ~ 38

Author(s):

Yu-Tao Xiang ◽

Yong-Zhen Weng ◽

Chi-Ming Leung ◽

Wai-Kwong Tang ◽

Gabor S. Ungvari

Keyword(s):

Quality Of Life ◽

Hong Kong ◽

Subjective Quality ◽

Clinical Factors ◽

Subjective Quality Of Life

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T250. CLINICAL CORRELATES OF SUBJECTIVE QUALITY OF LIFE IN INDIVIDUALS WITH AT-RISK MENTAL STATE FOR PSYCHOSIS IN HONG KONG

Schizophrenia Bulletin ◽

10.1093/schbul/sby016.526 ◽

2018 ◽

Vol 44 (suppl_1) ◽

pp. S214-S215

Author(s):

Irving Teng ◽

Wing Chung Chang ◽

Hoi Ching Lee ◽

Cheuk Fei Wong ◽

Sui Fung Wo ◽

...

Keyword(s):

Quality Of Life ◽

At Risk ◽

Hong Kong ◽

Mental State ◽

Subjective Quality ◽

Subjective Quality Of Life ◽

Clinical Correlates ◽

At Risk Mental State

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Examination of the Philadelphia Geriatric Morale Scale as a Subjective Quality-of-Life Measure in Elderly Hong Kong Chinese

The Gerontologist ◽

10.1093/geront/44.3.408 ◽

2004 ◽

Vol 44 (3) ◽

pp. 408-417 ◽

Cited By ~ 24

Author(s):

Eric Wong ◽

Jean Woo ◽

Elsie Hui ◽

Suzanne C. Ho

Keyword(s):

Quality Of Life ◽

Hong Kong ◽

Subjective Quality ◽

Hong Kong Chinese ◽

Subjective Quality Of Life ◽

Life Measure

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Effects of a Wonderful Life Program on the Wellbeing Behaviors, Life Satisfaction and Subjective Quality of Life of Community Elderly People in KOREA: Wonderful Life Program Includes SAFETY

J-Institute ◽

10.22471/crisis.2019.4.1.01 ◽

2019 ◽

Vol 4 (1) ◽

pp. 1-7

Author(s):

Mi-kyeong Byeon ◽

◽

Sun-jung Park ◽

Eun-young Choi ◽

◽

...

Keyword(s):

Quality Of Life ◽

Life Satisfaction ◽

Elderly People ◽

Subjective Quality ◽

Subjective Quality Of Life

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Cognitive determinants of community functioning and quality of life in homeless adults with mental illness: 6-year follow-up from the At Home/Chez Soi Study Toronto site

Psychological Medicine ◽

10.1017/s0033291721001550 ◽

2021 ◽

pp. 1-9

Author(s):

K. M. Gicas ◽

C. Mejia-Lancheros ◽

R. Nisenbaum ◽

R. Wang ◽

S. W. Hwang ◽

...

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Functional Outcomes ◽

Verbal Learning ◽

Subjective Quality ◽

Subjective Quality Of Life ◽

Homeless Adults ◽

Community Functioning ◽

At Home

Abstract Background High rates of physical and mental health comorbidities are associated with functional impairment among persons who are homeless. Cognitive dysfunction is common, but how it contributes to various functional outcomes in this population has not been well investigated. This study examines how cognition covaries with community functioning and subjective quality of life over a 6-year period while accounting for the effects of risk and protective factors. Methods Participants were 349 homeless adults (mean age = 39.8) recruited from the Toronto site of the At Home/Chez Soi study, a large Canadian randomized control trial of Housing First. Participants completed up to four clinical evaluations over 6 years. Factor scores were created to index verbal learning and memory (vLM) and processing speed-cognitive flexibility (PSCF). The primary outcomes were community functioning and subjective quality of life. Risk factors included lifetime homelessness, mental health diagnoses, medical comorbidity, and childhood adversity. Linear mixed-effects models were conducted to examine cognition-functional outcome associations over time, with resilience as a moderator. Results Better vLM (b = 0.787, p = 0.010) and PSCF (b = 1.66, p < 0.001) were associated with better community functioning, but not with quality of life. Resilience conferred a protective effect on subjective quality of life (b = 1.45, p = 0.011) but did not moderate outcomes. Conclusions Our findings suggest a need to consider the unique determinants of community functioning and quality of life among homeless adults. Cognition should be prioritized as a key intervention target within existing service delivery models to optimize long-term functional outcomes.

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