543 EEG-Based Deep Neural Network Model for Brain Age Prediction and Its Association with Patient Health Conditions

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A214-A214
Author(s):  
Yoav Nygate ◽  
Sam Rusk ◽  
Chris Fernandez ◽  
Nick Glattard ◽  
Jessica Arguelles ◽  
...  
Keyword(s):  
Neural Network ◽  
Deep Neural Network ◽  
Population Sample ◽  
Health Conditions ◽  
Apnea Hypopnea Index ◽  
Healthy Population ◽  
Brain Health ◽  
Patient Health ◽  
Drug Problems ◽  
Brain Age

Abstract Introduction Electroencephalogram (EEG) provides clinically relevant information for personalized patient health evaluation and comprehensive assessment of sleep. EEG-based indices have been associated with neurodegenerative conditions, psychiatric disorders, and metabolic and cardiovascular disease, and hold promise as a biomarker for brain health. Methods A deep neural network (DNN) model was trained to predict the age of patients using raw EEG signals recorded during clinical polysomnography (PSG). The DNN was trained on N=126,241 PSGs, validated on N=6,638, and tested on a holdout set of N=1,172. The holdout dataset included several categories of patient demographic and diagnostic parameters, allowing us to examine the association between brain age and a variety of medical conditions. Brain age was assessed by subtracting the individual’s chronological brain age from their EEG-predicted brain age (Brain Age Index; BAI), and then taking the absolute value of this variable (Absolute Brain Age Index; ABAI). We then constructed two regression models to test the relationship between BAI/ABAI and the following list of patient parameters: sex, BMI, depression, alcohol/drug problems, memory/concentration problems, epilepsy/seizures, diabetes, stroke, severe excessive daytime sleepiness (e.g., Epworth Sleepiness Scale ≥ 16; EDS), apnea-hypopnea index (AHI), arousal index (ArI), and sleep efficiency (SE). Results The DNN brain age model produced a mean absolute error of 4.604 and a Pearson’s r value of 0.933 which surpass the performance of prior research. In our regression analyses, we found a statistically significant relationship between the ABAI and: epilepsy and seizure disorders, stroke, elevated AHI, elevated ArI, and low SE (all p<0.05). This demonstrates these health conditions are associated with deviations of one’s predicted brain age from their chronological brain age. We also found patients with diabetes, depression, severe EDS, hypertension, and/or memory and concentration problems showed, on average, an elevated BAI compared to the healthy population sample (all p<0.05). Conclusion We show DNNs can accurately predict the brain age of healthy patients based on their raw, PSG derived, EEG recordings. Furthermore, we reveal indices, such as BAI and ABAI, display unique characteristics within different diseased populations, highlighting their potential value as novel diagnostic biomarker and potential “vital sign” of brain health. Support (if any):

scholarly journals DEAD WOOD DETECTION BASED ON SEMANTIC SEGMENTATION OF VHR AERIAL CIR IMAGERY USING OPTIMIZED FCN-DENSENET

2019 ◽  
Vol XLII-2/W16 ◽  
pp. 127-133 ◽  
Author(s):  
S. Jiang ◽  
W. Yao ◽  
M. Heurich
Keyword(s):  
Neural Network ◽  
Temperate Forest ◽  
Deep Neural Network ◽  
Dead Wood ◽  
Semantic Segmentation ◽  
Health Conditions ◽  
Learning Approaches ◽  
Forest Environment ◽  
Forest Park ◽  
Dead Trees

<p><strong>Abstract.</strong> The assessment of the forests’ health conditions is an important task for biodiversity, forest management, global environment monitoring, and carbon dynamics. Several research works were proposed to evaluate the state condition of a forest based on remote sensing technology. Concerning existing technologies, employing traditional machine learning approaches to detect the dead wood in aerial colour-infrared (CIR) imagery is one of the major trends due to its spectral capability to explicitly capturing vegetation health conditions. However, the complicated scene with background noise restricted the accuracy of existing approaches as those detectors normally utilized hand-crafted features. Currently, deep neural networks are widely used in computer vision tasks and prove that features learnt by the model itself perform much better than the hand-crafted features. The semantic image segmentation is a pixel-level classification task, which is best suitable to dead wood detection in very high resolution (VHR) mode because it enables the model to identify and classify very dense and detailed components on the tree objects. In this paper, an optimized FCN-DenseNet is proposed to detect dead wood (i.e. standing dead tree and fallen tree) in a complicated temperate forest environment. Since the appearance of dead trees generally occupies greatly different scales and sizes; several pooling procedures are employed to extract multi-scale features and dense connection is employed to enhance the inline connection among the scales. Our proposed deep neural network is evaluated over VHR CIR imagery (GSD-10cm) captured in a natural temperate forest in Bavarian national forest park, Germany, which has undergone on-site bark beetle attack. The results show that the boundary of dead trees can be accurately segmented, and the classification are performed with a high accuracy, even though only one labelled image with moderate size is used for training the deep neural network.</p>

scholarly journals Characterizing brain age in the Alzheimer's disease connectome project using a deep neural network pre‐trained on the UK Biobank

2021 ◽  
Vol 17 (S5) ◽  
Author(s):  
Nagesh Adluru ◽  
Veena A. Nair ◽  
Vivek Prabhakaran ◽  
Vishnu Bashyam ◽  
Shi‐Jiang Li ◽  
...  
Keyword(s):  
Neural Network ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Deep Neural Network ◽  
Uk Biobank ◽  
The Uk ◽  
Brain Age

Deep Neural Network Classification of I-123 Ioflupane SPECT

2020 ◽  
Author(s):  
David T. Wang ◽  
Brady Williamson ◽  
Thomas Eluvathingal ◽  
Bruce Mahoney ◽  
Jennifer Scheler
Keyword(s):  
Neural Network ◽  
Deep Neural Network ◽  
Neural Network Classification

Method of determination of the text direction on the image with the use of convolutional neural network

2020 ◽  
pp. 96-99
Author(s):  
P.L. Nikolaev
Keyword(s):  
Neural Network ◽  
Convolutional Neural Network ◽  
Deep Neural Network ◽  
Binary Classification ◽  
Synthetic Data ◽  
Real Data ◽  
Method Of Determination ◽  
Classification Of Images

This article deals with method of binary classification of images with small text on them Classification is based on the fact that the text can have 2 directions – it can be positioned horizontally and read from left to right or it can be turned 180 degrees so the image must be rotated to read the sign. This type of text can be found on the covers of a variety of books, so in case of recognizing the covers, it is necessary first to determine the direction of the text before we will directly recognize it. The article suggests the development of a deep neural network for determination of the text position in the context of book covers recognizing. The results of training and testing of a convolutional neural network on synthetic data as well as the examples of the network functioning on the real data are presented.

Underwater Fish Images Classification by Deep Neural Network

2020 ◽  
Author(s):  
Ala Supriya ◽  
Chiluka Venkat ◽  
Aliketti Deepak ◽  
GV Hari Prasad
Keyword(s):  
Neural Network ◽  
Deep Neural Network
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