scholarly journals Impaired autonomic cardiac regulation due to altered baroreceptor reflex sensitivity in conscious P2rX7 knockout rats

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Vladislav S Kuzmin ◽  
D'Anna L Potter ◽  
Sergey N Arkhipov ◽  
Tengis S Pavlov
2021 ◽  
Author(s):  
Sara Bachmann ◽  
Anne Auderset ◽  
Marie‐Anne Burckhardt ◽  
Gabor Szinnai ◽  
Melanie Hess ◽  
...  

2015 ◽  
Vol 61 ◽  
pp. 119-126 ◽  
Author(s):  
Pedram Ataee ◽  
Jin-Oh Hahn ◽  
Guy A. Dumont ◽  
Hossein A. Noubari ◽  
W. Thomas Boyce

2017 ◽  
pp. 199-226
Author(s):  
Tatjana Lončar-Turukalo ◽  
Nina Japundžić-Žigon ◽  
Olivera Šarenac ◽  
Dragana Bajić

2018 ◽  
Vol 28 (10) ◽  
pp. 881-887 ◽  
Author(s):  
Théa Venet ◽  
Vincent Pichot ◽  
David Charier ◽  
Aurélien Scalabre ◽  
Hugues Patural

Physiology ◽  
1993 ◽  
Vol 8 (5) ◽  
pp. 223-228 ◽  
Author(s):  
S Oparil ◽  
JM Wyss

A complete atrial natriuretic factor (ANF) synthetic, processing, and effector system is found in rat brain. ANF in critical brain regions, including anterior hypothalamic area and nucleus tractus solitarii, contributes importantly to the tonic control of blood pressure, sympathetic outflow, and baroreceptor reflex sensitivity in the spontaneously hypertensive rat.


2012 ◽  
Vol 2 (1) ◽  
pp. 4 ◽  
Author(s):  
Elisabeth Ruiz Padial ◽  
Nieves Torres López ◽  
Javier Luna Bujaldón ◽  
Isabel Espadas Villanueva ◽  
Gustavo Reyes del Paso

The present study evaluates the cardiovascular effects of reflexology in a healthy sample. Forty-one participants were randomly assigned to one of three experimental groups: reflexology (n=15), non-professional foot massage (n=14), and a waiting time control group (n=12). Dependent variables were systolic, diastolic and mean blood pressure, inter-beat interval, heart rate variability and baroreceptor reflex sensitivity measured pre- and post- interventions. The study was performed during three 40-min sessions separated by weekly intervals. Results show that the three manipulations produce similar increases in inter-beat interval, heart rate variability and baroreceptor reflex sensitivity. Reflexology specifically produces an increase in blood pressure, which increases gradually over the three sessions. The parallel increase in heart rate variability and baroreceptor reflex sensitivity together with the increase in blood pressure suggest that reflexology is associated with a co-activation of both sympathetic and parasympathetic branches of the Autonomic Nervous System. These changes could be helpful in optimizing homeostatic activity, promoting the healing process and increasing the human organism’s capacity to respond adaptively to internal and external challenges. Finally, the observed physiological changes in the waiting-time control group shows the relevance of habituation processes and suggests the need for addition of waiting-time control groups in future studies.


2009 ◽  
Vol 87 (9) ◽  
pp. 736-742 ◽  
Author(s):  
Martin G. Frasch ◽  
Thomas Müller ◽  
Mark Szynkaruk ◽  
Matthias Schwab

Assessment of baroreceptor reflex sensitivity (BRS) in the ovine fetus provides insight into autonomic cardiovascular regulation. Currently, assessment of BRS relies on vasoactive drugs, but this approach is limited by feasibility issues and by the nonphysiologic nature of the stimulus. Thus we aimed to validate the method of spontaneous BRS assessment against the reference method of using vasoactive drugs in preterm (0.76 gestation, n = 16) and near-term (0.86 gestation, n = 16) chronically instrumented ovine fetuses. The BRS measures derived from the spontaneous and reference methods correlated at both gestational ages (R = 0.67 ± 0.03). The sequence method of spontaneous BRS measures also correlated both to the root mean square of standard deviations (RMSSD), which is a measure of fetal heart rate variability reflecting vagal modulation (R = 0.69 ± 0.03), and to fetal body weight (R = 0.65 ± 0.03), which is a surrogate for growth trajectory of each fetus. The methodology presented may aid in developing new models to study BRS and cardiovascular control in ovine fetus in the last trimester of pregnancy.


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