scholarly journals Intestinal alkaline phosphatase is a diagnostic biomarker for necrotizing enterocolitis in preterm infants

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Rebecca Buckley ◽  
Maya Heath ◽  
Zeromeh Gerber ◽  
Porcha Davis ◽  
Laura Linneman ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Preterm Infants ◽  
Necrotizing Enterocolitis ◽  
Diagnostic Biomarker ◽  
Intestinal Alkaline Phosphatase

Alkaline phosphatase isoenzymes in the plasma of preterm and term infants: serial measurements and clinical correlations.

1987 ◽  
Vol 33 (10) ◽  
pp. 1783-1787 ◽  
Author(s):  
P M Crofton ◽  
R Hume
Keyword(s):  
Alkaline Phosphatase ◽  
Preterm Infants ◽  
Intestinal Alkaline Phosphatase ◽  
Group Status ◽  
Term Infants ◽  
Alkaline Phosphatase Isoenzymes ◽  
Preterm Babies ◽  
Clinical Correlations ◽  
Serial Measurements ◽  
Milk Feeding

Abstract Serial measurements of the bone and fetal intestinal isoenzymes of alkaline phosphatase (EC 3.1.3.1) in the plasma of 43 term and 43 preterm infants, from birth to six weeks later, indicate that the bone isoenzyme gradually increases over this period in both preterm and term infants fed with unsupplemented commercial formulas. Preterm babies given formula supplemented with calcium (with or without additional phosphate) had significantly lower bone isoenzyme activities for most of the study period. The concentrations of fetal intestinal isoenzyme increased, under the stimulation of milk feeding, from generally undetectable at birth to a peak during the first two weeks postpartum, and then declined. This increase was highly significantly negatively correlated with gestational age, the preterm infants having a much higher and more prolonged increase in this isoenzyme than did term infants. Unlike the adult isoenzyme, fetal intestinal alkaline phosphatase in plasma showed no relationship with blood group status.

Deficiency of intestinal alkaline phosphatase in newborns predisposes to necrotizing enterocolitis in a neonatal rat model

2011 ◽  
Vol 213 (3) ◽  
pp. S85
Author(s):  
Rebecca M. Rentea ◽  
Jill S. Whitehouse ◽  
Jennifer L. Liedel ◽  
Kirkwood A. Pritchard ◽  
Alan N. Mayer ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Necrotizing Enterocolitis ◽  
Rat Model ◽  
Neonatal Rat ◽  
Intestinal Alkaline Phosphatase ◽  
Neonatal Rat Model

scholarly journals Intestinal alkaline phosphatase to treat necrotizing enterocolitis

2015 ◽  
Vol 196 (2) ◽  
pp. 235-240 ◽  
Author(s):  
Ben E. Biesterveld ◽  
Shannon M. Koehler ◽  
Nathan P. Heinzerling ◽  
Rebecca M. Rentea ◽  
Katherine Fredrich ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Necrotizing Enterocolitis ◽  
Intestinal Alkaline Phosphatase

The Protective Role of Intestinal Alkaline Phosphatase in Necrotizing Enterocolitis

2010 ◽  
Vol 158 (2) ◽  
pp. 201
Author(s):  
J.S. Whitehouse ◽  
K.M. Riggle ◽  
D.P. Purpi ◽  
A.N. Mayer ◽  
K.A. Pritchard ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Necrotizing Enterocolitis ◽  
Protective Role ◽  
Intestinal Alkaline Phosphatase

The potential of gut microbiota and fecal volatile organic compounds analysis as early diagnostic biomarker for necrotizing enterocolitis and sepsis in preterm infants

2018 ◽  
Vol 12 (5) ◽  
pp. 457-470 ◽  
Author(s):  
Daniel Johannes Cornelis Berkhout ◽  
Hendrik Johannes Niemarkt ◽  
Nanne Klaas Hendrik de Boer ◽  
Marc Alexander Benninga ◽  
Timotheüs Gualtherus Jacob de Meij
Keyword(s):  
Volatile Organic Compounds ◽  
Gut Microbiota ◽  
Organic Compounds ◽  
Preterm Infants ◽  
Necrotizing Enterocolitis ◽  
Diagnostic Biomarker ◽  
Volatile Organic ◽  
Early Diagnostic
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