scholarly journals Differential expression of gut bacterial phenylalanine reductive pathway potentially modulates the host susceptibility to acetaminophen‐induced liver injury

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Xiaotong Yang ◽  
Sungjoon Cho ◽  
Hyunwoo Lee ◽  
Hyunyoung Jeong
Keyword(s):  
Liver Injury ◽  
Differential Expression ◽  
Host Susceptibility ◽  
Reductive Pathway

Sex differences in hepatic gene expression in a rat model of ethanol-induced liver injury

2002 ◽  
Vol 93 (3) ◽  
pp. 1057-1068 ◽  
Author(s):  
Stasa D. Tadic ◽  
Mary S. Elm ◽  
Ha-Sheng Li ◽  
Gijsberta J. Van Londen ◽  
Vladimir M. Subbotin ◽  
...  
Keyword(s):  
Sex Differences ◽  
Liver Injury ◽  
Differential Expression ◽  
Female Rats ◽  
Male Rats ◽  
Hepatic Gene Expression ◽  
Alcoholic Liver Injury ◽  
Experimental Animal Models ◽  
Number Of Genes ◽  
Hepatic Genes

Sex differences in susceptibility to alcohol-induced liver injury have been observed in both humans and experimental animal models. Using a standard model of alcohol-induced fatty liver injury and microarray analysis, we have identified differential expression of hepatic genes in both sexes. The genes that exhibit differential expression are of three types: those that are changed only in male rats fed alcohol, those that change in only female rats fed alcohol, and those that change in both sexes, although not always in the same manner. Certain of the differentially expressed genes have previously been identified as participants in the induction of alcohol-induced liver injury. However, this analysis has identified a number of genes that heretofore have not been implicated in alcoholic liver injury; such genes may provide new areas of investigation into the pathogenesis of this disease.

Differential expression of tenascin isoforms in acute and chronic human liver injury

1998 ◽  
Vol 28 ◽  
pp. 85
Author(s):  
G. Pellegrini ◽  
C. Grappone ◽  
L. Zardi ◽  
L. Borsi ◽  
D. Schuppan ◽  
...  
Keyword(s):  
Liver Injury ◽  
Differential Expression ◽  
Human Liver

Differential expression of ASS1 in serous and non-serous ovarian carcinomas

2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Dong-Joo Cheon ◽  
Ann E. Walts ◽  
Jessica A. Beach ◽  
Jenny Lester ◽  
John S. Bomalaski ◽  
...  
Keyword(s):  
Differential Expression ◽  
Ovarian Carcinomas

Effects of Steroids on Fetal Rat Liver

1969 ◽  
Vol 27 ◽  
pp. 350-351
Author(s):  
F. G. Zaki
Keyword(s):  
Liver Injury ◽  
Rat Liver ◽  
Fetal Liver ◽  
Dosage Level ◽  
Maternal Plasma ◽  
Methyl Prednisolone ◽  
Fetal Rat ◽  
Toxic Agents ◽  
Fetal Rat Liver ◽  
Neonatal Liver

Fetal and neonatal liver injury induced by agents circulating in maternal plasma, even though well recognized, its morphological manifestations are not yet established. As part of our studies of fetal and neonatal liver injury induced by maternal nutritional disorders, metabolic impairment and toxic agents, the effects of two anti-inflammatory steroids have been recently inves tigated.Triamcinolone and methyl prednisolone were injected each in a group of rats during pregnancy at a-dosage level of 2 mgm three times a week. Fetal liver was studied at 18 days of gestation. Litter size and weight markedly decreased than those of control rats. Stillbirths and resorption were of higher incidence in the triamcinolone group than in those given the prednisolone.

Sign in / Sign up

Export Citation Format

Share Document