COMPARISON OF LOWER-BODY MUSCLE PERFORMANCE IN ELDERLY WOMEN WITH AND WITHOUT A HISTORY OF FALLS

Background: Identification of subjects with a progressive disease phenotype is an urgent need in the pharmaceutical industry where most of the recent clinical trials in Alzheimer’s disease have failed. Objectives: The objective of this study was to identify subgroups of individuals with objective cognitive impairment (OCI), who were most likely to progress to dementia and to identify the risk factors associated with progression. Design: Prospective cohort study. Setting: Population-based. Participants: 5,380 elderly women from Denmark. Measurements: The Short Blessed Test and a category fluency test with animal naming, was used to assess cognitive function, and to classify them into different groups of OCI. Results: OCI was identified in 852 subjects at baseline. The risk of dementia was elevated for OCI subjects as compared to subjects with normal cognition (HR 1.46[1.19-1.79]). The courses of OCI were studied in a sub-cohort who completed the cognitive assessment at both the baseline and the follow-up visit (n = 1,933). Of these subjects 203 had OCI at baseline. The multi-domain subtypes of OCI were associated with progressive OCI. Subjects most likely to progress were older, physically inactive, had a higher level of total cholesterol (>6.5 mmol/L) and had a history of depression as compared to subjects with a non-progressive course of OCI. Conclusions: In this cohort we identified a risk profile associated with progression from OCI in older women. The degree of impairment at baseline was an important predictor of conversion to dementia, additionally several modifiable risk factors were associated with progression.

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Effects of training volume on lower-body muscle strength in untrained young men: a contralateral control study

Motriz Revista de Educação Física ◽

10.1590/s1980-657420180003e008318 ◽

2018 ◽

Vol 24 (3) ◽

Author(s):

Marcio A. Rinaldo ◽

Jeferson L. Jacinto ◽

Francis L. Pacagnelli ◽

Leonardo Shigaki ◽

Alex S. Ribeiro ◽

...

Keyword(s):

Muscle Strength ◽

Young Men ◽

Training Volume ◽

Lower Body ◽

Body Muscle ◽

Control Study

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Traumatic Deaths from Dog Attacks in the United States

PEDIATRICS ◽

10.1542/peds.69.2.193 ◽

1982 ◽

Vol 69 (2) ◽

pp. 193-196

Author(s):

Lee E. Pinckney ◽

Leslie A. Kennedy

Keyword(s):

United States ◽

Medical Literature ◽

Elderly Women ◽

The United States ◽

Pet Dogs ◽

History Of

A newspaper survey and search of the medical literature identified 74 deaths from dog attacks, 51 of which occurred in a designated five-year study period. Most attacks were by single pet dogs without a preceding history of viciousness and without known provocation by the victim. The highest number of deaths (23) occurred in infants less than 1 year of age. Most of the remaining victims were children aged 1 through 8 years, and elderly women.

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Are gait parameters related to knee pain, urinary incontinence and a history of falls in community-dwelling elderly women?

Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics ◽

10.3143/geriatrics.50.528 ◽

2013 ◽

Vol 50 (4) ◽

pp. 528-535 ◽

Cited By ~ 7

Author(s):

Hunkyung Kim ◽

Takao Suzuki ◽

Hideyo Yoshida ◽

Hiroyuki Shimada ◽

Yukari Yamashiro ◽

...

Keyword(s):

Urinary Incontinence ◽

Knee Pain ◽

Elderly Women ◽

Community Dwelling ◽

Gait Parameters ◽

History Of

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Effect of Training Phase on Physical and Physiological Parameters of Male Powerlifters

Sports ◽

10.3390/sports8080106 ◽

2020 ◽

Vol 8 (8) ◽

pp. 106

Author(s):

Daniel Hackett ◽

Guy Wilson ◽

Lachlan Mitchell ◽

Marjan Haghighi ◽

Jillian Clarke ◽

...

Keyword(s):

Body Composition ◽

Longitudinal Research ◽

Phase 1 ◽

Physiological Parameters ◽

Muscle Performance ◽

Training Phase ◽

Lower Body ◽

Phase 3 ◽

Dietary Practices ◽

Preparatory Phase

Longitudinal research on training and dietary practices of natural powerlifters is limited. This study investigated the effect of phases of training on physical and physiological parameters in male natural powerlifters. Nine participants completed testing at two time points: (i) preparatory phase (~3 months prior to a major competition) and (ii) competition phase (1–2 weeks from a major competition). No significant changes between training phases were found for muscle strength and power. A trend for significance was found for decreased muscle endurance of the lower body (−24.4%, p = 0.08). A significant increase in leg lean mass was found at the competition phase (2.3%, p = 0.04), although no changes for other body composition measures were observed. No change was observed for any health marker except a trend for increased urinary creatinine clearance at the competition phase (12.5%, p = 0.08). A significant reduction in training volume for the lower body (−75.0%, p = 0.04) and a trend for a decrease in total energy intake (−17.0%, p = 0.06) was observed during the competition phase. Despite modifications in training and dietary practices, it appears that muscle performance, body composition, and health status remain relatively stable between training phases in male natural powerlifters.

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