Accumulation of p53 in relation to long-term prognosis in colorectal carcinoma

1997 ◽  
Vol 9 (2) ◽  
pp. 183-186 ◽  
Author(s):  
Teresa Starzynska ◽  
Mike Bromley ◽  
Krzysztof Marlicz ◽  
Stephen A. Roberts ◽  
Michal Ucinski ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Long Term Prognosis

scholarly journals Immune Microenvironment in Colorectal Cancer: A New Hallmark to Change Old Paradigms

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Luis de la Cruz-Merino ◽  
Fernando Henao Carrasco ◽  
David Vicente Baz ◽  
Esteban Nogales Fernández ◽  
Juan José Reina Zoilo ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Prognostic Factors ◽  
Colorectal Carcinoma ◽  
Tumor Cells ◽  
Immune Reaction ◽  
Current Knowledge ◽  
Immune Microenvironment ◽  
Long Term Prognosis ◽  
Infiltrating Lymphocytes

Impact of immune microenvironment in prognosis of solid tumors has been extensively studied in the last few years. Specifically in colorectal carcinoma, increased knowledge of the immune events around these tumors and their relation with clinical outcomes have led to consider immune microenvironment as one of the most important prognostic factors in this disease. In this review we will summarize and update the current knowledge with respect to this intriguing and complex new hallmark of cancer, paying special attention to infiltration by T-infiltrating lymphocytes and their subtypes in colorectal cancer, as well as its eventual clinical translation in terms of long-term prognosis. Finally, we suggest some possible investigational approaches based on combinatorial strategies to trigger and boost immune reaction against tumor cells.

scholarly journals Salvage Endoscopic Full-Thickness Resection of Colorectal Carcinoma after Radiotherapy in a Patient Not Eligible for Surgery

2020 ◽  
pp. 1-3
Author(s):  
Ramon-Michel Schreuder ◽  
Clément Huysentruyt ◽  
Erik J. Schoon ◽  
Israt J. Hossein ◽  
Jeltsje S. Cnossen ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Residual Tumor ◽  
Curative Treatment ◽  
Full Thickness ◽  
Sigmoid Carcinoma ◽  
Severe Comorbidity ◽  
Endoscopic Full Thickness Resection ◽  
Long Term Prognosis ◽  
Recurrent Malignancy

For early, superficial colorectal carcinoma, endoscopic resection is an accepted curative treatment with an excellent long-term prognosis. Our report is the first report describing endoscopic full-thickness resection (eFTR) of residual recto-sigmoid carcinoma after radiotherapy. Our patient with cT2N0M0 recto-sigmoid carcinoma had been treated with radiotherapy because severe comorbidity precluded surgical resection. When the residual tumor was observed endoscopically, complete remission was achieved by endoscopic full thickness resection. There were no endoscopic or radiological signs of recurrent malignancy after the two-years follow-up period. In selected cases, eFTR after radiotherapy could be a curative treatment option.

scholarly journals The influence of postoperative complications on long-term prognosis in patients with colorectal carcinoma

2020 ◽  
Vol 35 (6) ◽  
pp. 1055-1066 ◽  
Author(s):  
Clemens Beck ◽  
Klaus Weber ◽  
Maximilian Brunner ◽  
Abbas Agaimy ◽  
Sabine Semrau ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Colorectal Carcinoma ◽  
Long Term Prognosis

scholarly journals Study of the Long-Term Prognosis of Curative Obstructive Colorectal Carcinoma —One-Stage Surgery vs. Two-Stage Surgery—

2015 ◽  
Vol 68 (4) ◽  
pp. 221-226
Author(s):  
Hiroyuki Takahashi ◽  
Koji Mikami ◽  
Yukiko Hirano ◽  
Daijiro Higashi ◽  
Kitaro Futami ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Two Stage ◽  
One Stage ◽  
Long Term Prognosis

scholarly journals Evaluation of p53 protein expression as a marker for long-term prognosis in colorectal carcinoma

1995 ◽  
Vol 71 (6) ◽  
pp. 1257-1262 ◽  
Author(s):  
J-WR Mulder ◽  
IO Baas ◽  
MM Polak ◽  
SN Goodman ◽  
GJA Offerhaus
Keyword(s):  
Colorectal Carcinoma ◽  
Protein Expression ◽  
P53 Protein ◽  
P53 Protein Expression ◽  
Long Term Prognosis

Curative Resection of T1 Colorectal Carcinoma: Risk of Lymph Node Metastasis and Long-Term Prognosis

2005 ◽  
Vol 48 (6) ◽  
pp. 1182-1192 ◽  
Author(s):  
Huann-Sheng Wang ◽  
Wen-Yih Liang ◽  
Tzu-Chen Lin ◽  
Wei-Shone Chen ◽  
Jeng-Kae Jiang ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Colorectal Carcinoma ◽  
Curative Resection ◽  
Node Metastasis ◽  
T1 Colorectal Carcinoma ◽  
Long Term Prognosis ◽  
Carcinoma Risk

Long-term prognosis of cerebral venous sinus thrombosis in childhood

2004 ◽  
Vol 46 (08) ◽  
Author(s):  
Els LLM De Schryver ◽  
Ingrid Blom ◽  
Kees PJ Braun ◽  
L Jaap Kappelle ◽  
Gabriël JE Rinkel ◽  
...  
Keyword(s):  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Long Term Prognosis
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