scholarly journals THE ROLE OF GENES COMBINATION IN ESSENTIAL ARTERIAL HYPERTENSION

2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e157
Author(s):  
Yuliia Repchuk ◽  
Larisa Sydorchuk ◽  
Semen Biletsky ◽  
Oksana Petrynych ◽  
Marianna Semianiv ◽  
...  
1997 ◽  
Vol 10 (3) ◽  
pp. 369-372 ◽  
Author(s):  
S. Giuffrida ◽  
S. De Luca ◽  
L. Tomarchio ◽  
P. Milone ◽  
D. Restivo ◽  
...  

We report a case of isolated left peripheral hypoglossal nerve palsy caused by neurovascular compression associated with essential arterial hypertension. MR and MR-angiography revealed an anomalous course of the left vertebral artery and left PICA. A similar case, without arterial hypertension, was reported by Rollnik et Al. According to Jannetta's hypothesis neurovascular compression of the brain stem may cause essential arterial hypertension. To our knowledge no other similar case of peripheral hypoglossal palsy and arterial hypertension caused by neurovascular compression has been reported. The possible role of neurovascular compression in the pathogenesis of essential hypertension is briefly discussed.


2017 ◽  
Vol 96 (3) ◽  
pp. 34-39 ◽  
Author(s):  
A. S. Kosovtseva ◽  
◽  
L. I. Kolesnikova ◽  
L. V. Rychkova ◽  
V. M. Polyakov ◽  
...  

Author(s):  
Elena Korneeva ◽  
Mikhail Voevoda ◽  
Sergey Semaev ◽  
Vladimir Maksimov

Results of the study related to polymorphism of ACE gene (rs1799752)‎, integrin αIIbβ3, and CSK gene (rs1378942) influencing development of arterial hypertension in young patients with metabolic syndrome are presented. Hypertension as a component of the metabolic syndrome was detected in 15.0% of young patients. Prevalence of mutant alleles of the studied genes among the examined patients was quite high, so homozygous DD genotype was found in 21.6%, and mutant D allele of the ACE gene in 47.4%. A high risk of hypertension in patients with MS was detected in carriers of the T allele of the CSK (rs1378942) gene – 54.8%, which was most often observed in a combination of polymorphic ACE and CSK gene loci (p = 0.0053).


2016 ◽  
Vol 15 (1) ◽  
pp. 12-13
Author(s):  
Adaani E. Frost ◽  
Harrison W. Farber

Dramatic advances in therapy for pulmonary arterial hypertension (PAH) in the last 20 years have improved survival from a median of 2.5 years in the pretreatment era to 7.5 years currently. However, impressive as that may seem, it is important to note that a median survival of 7.5 years is equivalent to that of surgically resected non-small cell lung cancer, thus underscoring the importance of lung transplantation as a treatment option in patients with PAH. In this edition of Advances, Edelman has reviewed the pathway to transplantation for patients with PAH, detailing the recommendations for timing of referral, listing for lung transplantation, the role of the lung allocation score in allocating a donor organ, and the outcome of lung transplantation.


Author(s):  
Mustafa Yildiz ◽  
Alparslan Sahin ◽  
Michael Behnes ◽  
İbrahim Akin

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