Three-Year Follow-up of Biomicroscopy Signs and Refractive Status in Patients Wearing Lotrafilcon A Lenses

2005 ◽  
Vol 31 (6) ◽  
pp. 263-267 ◽  
Author(s):  
Bill Long ◽  
Florence Malet ◽  
Marie Lejeune ◽  
Marie-No??lle George-Vicariot ◽  
Roland Pagot ◽  
...  
Keyword(s):  
2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Mohammed Iqbal Hafez Saleem ◽  
Hosam A. Ibrahim Elzembely ◽  
Mortada Ahmed AboZaid ◽  
Mohammed Elagouz ◽  
Ahmed Mohamed Saeed ◽  
...  

Purpose. To analyze the results of three-year outcomes of combined epithelium-on cross-linking with femtosecond laser ICRS (cross-linking PLUS) for keratoconus management. Design. A retrospective multicenter clinical study. Methods. 43 eyes of 38 patients were subjected to preoperative and postoperative UCVA, BCVA, refraction, Pentacam pachymetry, and keratometry examinations at 3-, 6-, 12-, 24-, and 36-month follow-up period. Results. The preoperative and postoperative mean UCVA was 1.30 ± 0.48 (logMAR ± SD) and 0.82 ± 0.22 respectively. The preoperative and postoperative mean BCVA was 0.90 ± 0.40 and 0.60 ± 0.30, respectively. The preoperative and postoperative mean K average was 50.63 ± 0.87 (D ± SD) and 45.56 ± 0.98, respectively. The preoperative and postoperative mean pachymetry was 471 ± 92.36 (μm ± SD) and 423 ± 39.58, respectively. The preoperative and postoperative mean astigmatism was 7.55 ± 1.75 and 3.39 ± 1.26, respectively. One eye showed ICRS edge exposure while 6 eyes showed progression of keratoconus. Conclusion. CXL PLUS was proved to be a successful procedure to halt progression (mainly by CXL) and to correct the refractive status of the keratoconic eye (mainly by ICRS). CXL PLUS performed a synergistic action correcting and maintaining the correction of both myopic and astigmatic components of keratoconus.


2021 ◽  
Vol 12 (9) ◽  
pp. 126-129
Author(s):  
Kabindra Bajracharya ◽  
Anjita Hirachan ◽  
Kriti Joshi ◽  
Bimala Bajracharya

Background: In congenital and developmental cataract primary undercorrection of intraocular lens (IOL) power is a common practice. However, long-term refractive status of these children is largely unknown. Aims and Objective: To analyse refractive status after cataract surgery with undercorrected IOL power implantation in congenital and developmental cataract. Materials and Methods: This study was descriptive, retrospective conducted for three years from 1st January 2013 to 31st December 2015. The children (> 6 months to <=7 years of age) who underwent cataract surgery for congenital and developmental cataract with a primary IOL implantation and had reached the age of 8 years were studied. The data were collected in terms of demography, axial length, biometry, IOL implanted, hyperopic correction and postoperative refractive status at 8 years. Results: Total numbers of children operated were 181 with total eyes 288. Unilateral cases were 74 (40.88%) and bilateral 107 (59.12%). Male were 121 (66.85%) and female were 60 (33.15%) with male is to female ratio of 2:1. Right eye was involved in 152 (52.8%) and left eye 136 (47.2%). The mean axial length at the age of one year was 20.75 mm, and gradually increased as age increased which was 22.47 mm at 6 years. The mean biometry was 27.9 diopter (D) at the age of one year which gradually decreased as age increased. Of the total 288 congenital cataract operated, complete follow-up documents were available for 77 (26.74%) eyes up to 8 years which showed emmetropia achieved in 25.97%, myopia in 28.57% and hypermetropia in 45.45%. Conclusion: Primary IOL implantation with hyperopic correction is accepted practice in congenital and developmental cataract. Emmetropia can be achieved however some hyperopic or myopic refractive status at the age of 8 years is not a surprise. Myopic shift continues as the age increases. Parent awareness for early detection and surgery, optical correction and regular follow-up are essential for good outcome.


2020 ◽  
Author(s):  
Ashjan Bamahfouz ◽  
Serene Jouhargy ◽  
Ahmed Basheikh ◽  
Nawaf [email protected] ◽  
Yaser Elhams ◽  
...  

BACKGROUND Keratoconus (KC) is a progressive, bilateral, asymmetric corneal degeneration. KC is as a common disease in the general population, with prevalence ranging up to 200 per 100 000. Twenty percent of keratoconus patients present with irregular astigmatism leading to severe visual deterioration (1) . The inciting mechanism for keratoconus remains unknown, however genetic and environmental factors have been implicated. Environmental factors include excessive eye rubbing, allergy and sun exposure which can lead to greater expression of reactive oxygen species (2). Collagen cross linkage (CXL) is now an established treatment in isolation and in conjunction with other modalities of manging keratoconus (3, 4) . Keratoconus is highly prevalent in Saudi Arabia (5). CXL is also an established procedure in different eye institutions of the Kingdom with promising outcomes (6, 7). The earlier publications from central, eastern and western cities of the Kingdom had one year follow up. To the best of our knowledge, outcome of intervention from Macca city of western Saudi Arabia with a long term follow up is not available that could add to literature. We present outcomes of collagen cross linkage treatment and its determinants after 18 months in eyes with keratoconus at Macca, Saudi Arabia. OBJECTIVE To evaluate impact of 18 months after collagen cross linkage treatment and its determinants in eyes with keratoconus in Western Saudi Arabia. METHODS This was a one armed cohort study. Cases of keratoconus treated by Collagen cross linkage treatment (CXL) at our institute between 2015 and 2016 were included. Demographic data and grade of keratoconus (Amsler - Krumiech classification) at presentation were correlated to change in corneal parameters 18 months after CXL compared to that at presentation. RESULTS Our cohort had 45 eyes with keratoconus. Stage I, II, III and IV keratoconus were 13,14,2 and 16 eyes respectively. The K max significantly declined (Wilcoxon P = 0.05). The success of stabilizing corneal ectasia was achieved in 29/39 = 74.4%. Spherical equivalent refractive status changed from median -1.5D to -2.5D (WP =0.002). Central corneal thickness significantly reduced from median 471 to 460 ((WP =0.001). The Best corrected Visual acuity remained same 0.6 at 18 months follow up. Kmax based stabilization of cornea was not associated to the grade of keratoconus. (c2 = 2.2, P = 0.1). Stabilization of keratoconus was not associated to gender (P = 0.9) and laterality (P = 0.3). CONCLUSIONS The steepening of cornea stabilized 18 months after collagen cross linkage treatment. But vision remained same and cornea thinned out. There was a myopic shift for refractive status. Stabilization of corneal parameters did not vary significantly by grades of keratoconus. CLINICALTRIAL Keratoconus; corneal dystrophies; corneal ectasia; collagen cross linkage; CXL.


2020 ◽  
Vol 103 (6) ◽  
pp. 566-571

Objective: To determine the difference of refraction measured by cycloplegic retinoscopy (CR) and non-cycloplegic subjective refraction (NS). Materials and Methods: The present descriptive study included normal children aged 6 to 15 years with refractive error. The refractive status was measured by CR and cycloplegic autorefractometer (CA) at the initial visit. At 2-week follow-up, the refraction was measured with non-cycloplegic autorefractometer (NA) and NS. The spherical equivalent (SE) from participants’ right eye was used in the data analyses. Results: Forty-four participants were included in this study with a mean age of 9±3 years and 22 (50%) were male. Overall, the median (Q₁, Q₃) of SE by CR, CA, NS, and NA were –1.00 (–2.50, 0.25), –1.63 (–2.63, –0.50), –1.63 (–2.50, –1.00), and –1.88 (–2.88, –1.13) diopters (D), respectively. The SE by CR was 0.56 D more than NS (p<0.001), and 0.38 D more than CA (p<0.001). The SE by NS was 0.25 D more than NA (p=0.008). By using the CR method, 11 (25%) participants were classified in the hyperopic group (positive SE) and 33 (75%) in the myopic group (negative SE). In the hyperopic group, the median (Q₁, Q₃) of SE by CR and NS were 0.75 (0.50, 1.75) and –0.63 (–1.00, 1.38) D, respectively. The refraction by CR was 1.50 D more than by NS (p=0.003). In the myopic group, the median (Q₁, Q₃) of SE by CR and NS were –1.50 (–2.50, –0.75) and –2.00 (–3.25, –1.50) D, respectively. The refraction by CR was 0.50 D more than NS (p<0.001). Conclusion: The refraction in children aged 6 to 15 years measured by CR was significantly more than NS in the participants. The authors should decrease the number of refractions obtained from CR when prescribing glasses to hyperopic children. Keywords: Refractive error, Children, Cycloplegic retinoscopy, Subjective refraction, Cycloplegic autorefractor, Manifest autorefractor


2017 ◽  
Vol 80 (10) ◽  
pp. 673-678
Author(s):  
Tung-Mei Kuang ◽  
Su-Ying Tsai ◽  
Catherine Jiu-Ling Liu ◽  
Yu-Chieh Ko ◽  
Shui-Mei Lee ◽  
...  

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Rana Muhammad Mohsin Javaid ◽  
Nasir Chaudhary ◽  
Rehab Habib ◽  
Asad Aslam Khan ◽  
Kashif Siddique

Purpose:  To determine the mean change in refractive status after Levator muscle resection in patients of simple congenital ptosis. Study Design:  Quasi Experimental study. Place and Duration of Study:  This study was carried out at Institute of Ophthalmology, King Edward Medical University, Mayo Hospital Lahore, from 2014 to 2015. Material & Methods:  Fifty patients were selected under the age of 12 years with no sex predilection presenting with simple congenital ptosis of pupil sparing type. Patients with neurogenic, aponeurotic ptosis, mechanical ptosis, Blepharophimosis syndrome, patients with previous failed ptosis surgery and patients with corneal anomalies were excluded. After history and examination, Cycloplegic retinoscopy was done, which was repeated after surgical intervention. All interventions were done by a single ophthalmic surgeon. The patients were examined and discharged on the second post operative day. All data including preoperative and postoperative recordings of spherical and cylindrical values were collected on a self-designed proforma. Follow up period was extended to 3 months. At 3rd month cycloplegic retinoscopy was done and change in character of refractive status was analyzed. Mean change in refractive status was calculated by difference of preoperative and postoperative sphere and cylinder values. Results:  Mean age of patients was 4.26 ± 3.78 years. Mean change in spherical value after treatment was 0.447 ± 0.339. This difference was statistically significant with p-value = 0.000. While mean change in cylindrical value after treatment was 0.640 ± 0.580. This difference in cylinder value after treatment was also statistically significant with p-value = 0.000. Conclusion:  Levator muscle resection has a significant effect on refractive status of the patients with congenital ptosis.


2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.


1999 ◽  
Vol 173 ◽  
pp. 189-192
Author(s):  
J. Tichá ◽  
M. Tichý ◽  
Z. Moravec

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.


Author(s):  
D.G. Osborne ◽  
L.J. McCormack ◽  
M.O. Magnusson ◽  
W.S. Kiser

During a project in which regenerative changes were studied in autotransplanted canine kidneys, intranuclear crystals were seen in a small number of tubular epithelial cells. These crystalline structures were seen in the control specimens and also in regenerating specimens; the main differences being in size and number of them. The control specimens showed a few tubular epithelial cell nuclei almost completely occupied by large crystals that were not membrane bound. Subsequent follow-up biopsies of the same kidneys contained similar intranuclear crystals but of a much smaller size. Some of these nuclei contained several small crystals. The small crystals occurred at one week following transplantation and were seen even four weeks following transplantation. As time passed, the small crystals appeared to fuse to form larger crystals.


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