Cardiovascular Risk Factors May Moderate Pharmacological Treatment Effects in Major Depressive Disorder

2005 ◽  
Vol 67 (5) ◽  
pp. 703-706 ◽  
Author(s):  
Dan V. Iosifescu ◽  
Nicoletta Clementi-Craven ◽  
Renerio Fraguas ◽  
George I. Papakostas ◽  
Timothy Petersen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Major Depressive Disorder ◽  
Cardiovascular Risk ◽  
Depressive Disorder ◽  
Cardiovascular Risk Factors ◽  
Pharmacological Treatment ◽  
Treatment Effects ◽  
Major Depressive

scholarly journals Brain white-matter hyperintensities and treatment outcome in major depressive disorder

2006 ◽  
Vol 188 (2) ◽  
pp. 180-185 ◽  
Author(s):  
Dan V. Iosifescu ◽  
Perry F. Renshaw ◽  
In Kyoon Lyoo ◽  
Ho Kyu Lee ◽  
Roy H. Perlis ◽  
...  
Keyword(s):  
Risk Factors ◽  
Major Depressive Disorder ◽  
Treatment Outcome ◽  
Cardiovascular Risk ◽  
White Matter ◽  
Depressive Disorder ◽  
Cardiovascular Risk Factors ◽  
White Matter Hyperintensities ◽  
Major Depressive ◽  
Brain White Matter

BackgroundAn increased incidence of brain white-matter hyperintensities has been described in major depressive disorder, but the impact of such hyperintensities on treatment outcome is still controversial.AimsTo investigate the relationship of brain white-matter hyperintensities with cardiovascular risk factors and with treatment outcome in younger people with major depressive disorder.MethodWe assessed brain white-matter hyperintensities and cardiovascular risk factors in 84 people with major depressive disorder prior to initiating antidepressanttreatment. We also assessed hyperintensities in 35 matched controls.ResultsWe found no significant difference in the prevalence of white-matter hyperintensities between the depression and the control groups. Left-hemisphere subcortical hyperintensities correlated with lower rates of treatment response. We found no correlation between global hyperintensity measures and clinical outcome. Brain white-matter hyperintensities correlated with hypertension and age and with total cardiovascular risk score.ConclusionsSubcortical white-matter hyperintensities in the left hemisphere (but not in other brain areas) may be associated with poor response to antidepressant treatment in major depression.

Major Depressive Disorder with Anger Attacks and Cardiovascular Risk Factors

2007 ◽  
Vol 37 (1) ◽  
pp. 99-111 ◽  
Author(s):  
Renerio Fraguas ◽  
Dan V. Iosifescu ◽  
Bettina Bankier ◽  
Roy Perlis ◽  
Nicoletta Clementi-Craven ◽  
...  
Keyword(s):  
Risk Factors ◽  
Major Depressive Disorder ◽  
Cardiovascular Risk ◽  
Depressive Disorder ◽  
Cardiovascular Risk Factors ◽  
Major Depressive ◽  
Anger Attacks

Major Depressive Disorder Is Associated With Cardiovascular Risk Factors and Low Omega-3 Index

2010 ◽  
Vol 72 (09) ◽  
pp. 1242-1247 ◽  
Author(s):  
Thomas C. Baghai ◽  
Gabriella Varallo-Bedarida ◽  
Christoph Born ◽  
Sibylle Häfner ◽  
Cornelius Schüle ◽  
...  
Keyword(s):  
Risk Factors ◽  
Major Depressive Disorder ◽  
Cardiovascular Risk ◽  
Depressive Disorder ◽  
Cardiovascular Risk Factors ◽  
Omega 3 ◽  
Major Depressive

Risk factors for dementia are not associated with cognitive dysfunction in young people with major depressive disorder

2019 ◽  
Vol 245 ◽  
pp. 140-144 ◽  
Author(s):  
Markus Donix ◽  
Robert Haussmann ◽  
Franziska Helling ◽  
Anne Zweiniger ◽  
Annett Werner ◽  
...  
Keyword(s):  
Risk Factors ◽  
Major Depressive Disorder ◽  
Young People ◽  
Depressive Disorder ◽  
Cognitive Dysfunction ◽  
Major Depressive
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