Morphea and Its Variants and the “Floating Sign”—An Additional Finding in Morphea

2014 ◽  
Vol 36 (6) ◽  
pp. 500-505 ◽  
Author(s):  
Tanya Angela Perez-Chua ◽  
Yelena G. Kisel ◽  
Kyung Hee Chang ◽  
Jag Bhawan
Keyword(s):  
2021 ◽  
pp. 135406882110468
Author(s):  
Don S Lee ◽  
Fernando Casal Bertoa

Electoral stability has been viewed as an essential condition for the healthy functioning of representative democracy. However, there is little agreement in the literature about what shapes the stability of the electorate in general nor much attention paid to that of the Asian electorates in particular. We propose historical legacies, uniquely testable in Asia, as central determinants, but also test for conventional factors examined in other regions. By analyzing more than 150 elections in 19 post-WWII Asian democracies, we find that certain types of authoritarian (military or personalist) and colonial (non-British) legacies have a detrimental impact on the stabilization of the electorate, while some of the findings from other regions apply also to Asia. Our additional finding that such effects of historical legacies, particularly authoritarian interludes, are attenuated and cease to be significant with sufficient maturation of democracy, has important implications for the way party systems develop and democracies consolidate.


1983 ◽  
Vol 157 (6) ◽  
pp. 1947-1957 ◽  
Author(s):  
F Zavala ◽  
A H Cochrane ◽  
E H Nardin ◽  
R S Nussenzweig ◽  
V Nussenzweig

We have used panels of monoclonal antibodies to circumsporozoite (CS) proteins of Plasmodium falciparium, P. vivax, and P. knowlesi to determine the number of topographically independent epitopes of these antigens. The results of competition binding assays indicated that single regions of the CS molecules were recognized by the homologous monoclonal antibodies. Competition binding assays were also used to study the specificity of antibodies contained in the sera of humans and monkeys that had developed sterile immunity after immunization with irradiated, intact sporozoites. We found that single monoclonal antibodies inhibited 70-95% of the specific binding of the polyclonal antibodies to crude extracts of sporozoites. It appears, therefore, that CS proteins are among the most immunogenic constituents of sporozoites, and that a single region of these molecules contains most of the immunogenic activity. An additional finding was that the immunodominant region of CS molecules is multivalent with regard to the expression of a single epitope. This was demonstrated by the ability of monomers of CS proteins to bind simultaneously two or more molecules of the same monoclonal antibody.


1973 ◽  
Vol 51 (3) ◽  
pp. 220-225 ◽  
Author(s):  
F. Coceani ◽  
P. M. Olley

Effects of various prostaglandin types on strips of lamb ductus arteriosus were investigated under anaerobic and aerobic conditions. Prostaglandins E1 and E2 relaxed markedly the anoxic ductus over a dose range from 10−9 to 10−5 M whereas they had little or no effect on the tissue after exposure to oxygen. This is in contrast to papaverine which relaxed the ductus to a similar degree before and after exposure to oxygen. An additional finding was that prostaglandins E1 and E2 are less active on the anoxic tissue depolarized by excess potassium. The greater effectiveness of prostaglandins on the anoxic ductus suggests a role for these compounds in the regulation of the vessel tone during fetal life.


2006 ◽  
Vol 36 (1) ◽  
pp. 59-81 ◽  
Author(s):  
T. A. Hall ◽  
Silke Hamann ◽  
Marzena Zygis

This article examines the motivation for phonological stop assibilations, e.g. /t/ is realized as [ts], [s] or [t∫] before /i/, from the phonetic perspective. Hall & Hamann (2006) posit the following two implications: (a) Assibilation cannot be triggered by /i/ unless it is also triggered by by /j/, and (b) voiced stops cannot undergo assibilations unless voiceless ones do. In the following study we present the results of two acoustic experiments with native speakers of German and Polish which support implications (a) and (b). In our experiments we measured the friction phase after the /t d/ release before the onset of the following high front vocoid for four speakers of German and Polish. We found that the friction phase of /tj/ was significantly longer than that of /ti/, and that the friction phase of /t/ in the assibilation context is significantly longer than that of /d/. Furthermore, we unexpectedly found that the friction phase of /tj/ is significantly longer than that of /di/. An additional finding not related to the topic of the present study was that the Polish voiceless stops of the four speakers tested showed aspiration, in contrast to phonetic descriptions of these sounds as unaspirated.


2002 ◽  
Vol 39 (2) ◽  
pp. 246-248
Author(s):  
Kazuki Okajima ◽  
Kiyofumi Asai ◽  
Toshimitsu Niwa ◽  
Shigeru Ohki ◽  
Hisanori Sobajima ◽  
...  

Author(s):  
Fabio Uribe ◽  
Angela I. Zuluaga ◽  
Walter León ◽  
Angela Restrepo

Biopsies from cutaneous and mucosal lesions from 40 patients with active paracoccidioidomycosis, were studied histopathologically. All cases exhibited chronic granulomatous inflammation and 38 also presented suppuration; this picture corresponded to the mixed mycotic granuloma (MMG). Pseudoepitheliomatous hyperplasia and the transepidermic (or epithelial) elimination of the parasite, were observed in all cases. In paracoccidioidomycosis elimination takes place through formation of progressive edema, accompained by exocytosis. The edema gives rise to spongiosis, microvesicles and microabscesses which not only contain the fungus but also, various cellular elements. Cells in charge of the phagocytic process were essentialy Langhans giant cells; PMN's, epithelioid and foreign body giant cells were poor phagocytes. An additional finding was the presence of fibrosis in most biopsies.


Author(s):  
Joseph Z. Glustein ◽  
Michal Weill ◽  
Avraham Steinberg

1978 ◽  
Vol 147 (2) ◽  
pp. 409-421 ◽  
Author(s):  
J M Weiler ◽  
R W Yurt ◽  
D T Fearon ◽  
K F Austen

Native rat mast cell macromolecular heparin proteoglycan and commercial hog heparin glycosaminoglycan chains inhibit generation of the amplification convertase, C3b, Bb. The inhibitory action of heparin is not due to chelation of magnesium. Heparin is most active in inhibiting convertase formation on cellular intermediates formed with the lowest C3b input and developed with the highest B concentration, thereby suggesting the receptor site for B on C3b as the point of heparin action. This interpretation is consistent with the demonstration that heparin prevents B utilization during the fluid phase interaction of C3b, B, and D. Inhibition is observed also when C3b,Bb generation takes place on cellular intermediates in the presence of P or C3NeF, which yield stabilized forms of the convertase. 50 times the concentration of heparin required to inhibit convertase generation does not accelerate the decay of the unstabilized or the C3NeF-stabilized convertases and has only a modest effect on the P-stabilized convertase. An additional effect of heparin is to impair beta1H-mediated decay-dissociation of C3b,Bb. The concentration of native or commercial heparin which prevents convertase formation is in the same range as that required for the demonstration of its anti-coagulant and anti-thrombin III cofactor activities. The additional finding that this inhibitory action of heparin can be expressed by the isolated mast cell granule suggests that native heparin may contribute to the modulation of the amplification pathway of complement.


2020 ◽  
Vol 1 (1) ◽  
pp. 91
Author(s):  
Julia Julia

This article examines the nafkah iddah of divorce lawsuit in the Islamic Law Compilation (KHI) Article 149 (b) and the verdict issued by the Supreme Court Number 137/K/AG/2007. It also analyses their legal basis based on the Jasser Auda’s maqāṣid al-sharī’ah approach concerning the preservation of life and treasure. The primariy objective of this article is to find the main differences between the KHI and the Verdict in determining the nafkah iddah of divorce suit. Although some scholars have concerned about the case of nafkah iddah, the Jasser Auda’s maqāṣid al-sharī’ah approach seems to be rare to be dealt with the case. Accordingly, the maqāṣidi approach will be mainly utilised in order to consider the effectiveness of both the KHI and the Verdict. This article finds that the KHI states that a wife who applies for a divorce is considered disloyal. As a consequence, she is undeserving of receiving nafkah iddah. The additional finding is that the Verdict decides that in the case of the divorce filled by the ex-wife, it brings a responsibility for the former husband to pay the nafkah iddah. From the perspective of maqāṣid al-sharī’ah, this article argues that the implementation of the Verdict gains better benefit rather than the KHI, because the legal basis evolved for the nafkah iddah of divorce suit is in line with the maqāṣid principles of the preservation of life and property. In the particular case, the principles tend to protect the ex-wife’s safety and welfare after the divorce.


2002 ◽  
Vol 31 (3) ◽  
pp. 383-418 ◽  
Author(s):  
SHONNA L. TRINCH ◽  
SUSAN BERK-SELIGSON

This study examines the types of interactional trouble that arise from narrative variation in institutional interviews. Specifically, we examine protective order interviews in which Latina women tell of domestic violence to paralegal interviewers charged with the duty of helping them obtain a protective order. Victims' narratives are shown to take different shapes, and paralegals respond to them in different pragmalinguistic ways, depending on how they diverge from institutional needs. The factors found most heavily to influence narrative outcomes are contextual ones, related to participant social roles, the type of communicative activity interlocutors perceive themselves to be engaged in, and their interactional goals. An additional finding is that when expectations of what constitutes appropriate speech behavior differ, the interlocutor holding greater institutional power will try to constrain the speech of the other, despite the fact that both appear to share an extralinguistic goal, in this case obtaining a protective order.


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