Long-term Follow-up Features on Rectal MRI During a Wait-and-See Approach After a Clinical Complete Response in Patients With Rectal Cancer Treated With Chemoradiotherapy

2011 ◽  
Vol 54 (12) ◽  
pp. 1521-1528 ◽  
Author(s):  
Doenja M. J. Lambregts ◽  
Monique Maas ◽  
Frans C. H. Bakers ◽  
Vincent C. Cappendijk ◽  
Guido Lammering ◽  
...  
2020 ◽  
Vol 46 (2) ◽  
pp. e19
Author(s):  
Hester Haak ◽  
Marit E. van der Sande ◽  
Doenja M.J. Lambregts ◽  
Regina G.H. Beets-Tan ◽  
Jarno Melenhorst ◽  
...  

2020 ◽  
pp. bjsports-2020-102525
Author(s):  
Stefanos Karanasios ◽  
Vasileios Korakakis ◽  
Rod Whiteley ◽  
Ioannis Vasilogeorgis ◽  
Sarah Woodbridge ◽  
...  

ObjectiveTo evaluate the effectiveness of exercise compared with other conservative interventions in the management of lateral elbow tendinopathy (LET) on pain and function.DesignSystematic review and meta-analysis.MethodsWe used the Cochrane risk-of-bias tool 2 for randomised controlled trials (RCTs) to assess risk of bias and the Grading of Recommendations Assessment, Development and Evaluation methodology to grade the certainty of evidence. Self-perceived improvement, pain intensity, pain-free grip strength (PFGS) and elbow disability were used as primary outcome measures.Eligibility criteriaRCTs assessing the effectiveness of exercise alone or as an additive intervention compared with passive interventions, wait-and-see or injections in patients with LET.Results30 RCTs (2123 participants, 5 comparator interventions) were identified. Exercise outperformed (low certainty) corticosteroid injections in all outcomes at all time points except short-term pain reduction. Clinically significant differences were found in PFGS at short-term (mean difference (MD): 12.15, (95% CI) 1.69 to 22.6), mid-term (MD: 22.45, 95% CI 3.63 to 41.3) and long-term follow-up (MD: 18, 95% CI 11.17 to 24.84). Statistically significant differences (very low certainty) for exercise compared with wait-and-see were found only in self-perceived improvement at short-term, pain reduction and elbow disability at short-term and long-term follow-up. Substantial heterogeneity in descriptions of equipment, load, duration and frequency of exercise programmes were evident.ConclusionsLow and very low certainty evidence suggests exercise is effective compared with passive interventions with or without invasive treatment in LET, but the effect is small.PROSPERO registration numberCRD42018082703.


Lung Cancer ◽  
1993 ◽  
Vol 10 (1-2) ◽  
pp. 47-54 ◽  
Author(s):  
Taisuke Ohonoshi ◽  
Hiroshi Ueoka ◽  
Shin Kawahara ◽  
Katsuyuki Kiura ◽  
Haruhito Kamei ◽  
...  

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