Improvement in Quality of Life and Pain in Patients With Hidradenitis Suppurativa After Wide Local Excision

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Julika Dick ◽  
Verena Kröhl ◽  
Alexander Enk ◽  
Wolfgang Hartschuh ◽  
Patrick Gholam
Keyword(s):  
Quality Of Life ◽  
Local Excision ◽  
Wide Local Excision ◽  
Hidradenitis Suppurativa

COMPARISON OF QUALITY OF LIFE AND EFFECTIVENESS OF LIMBERG FLAP VERSUS LAY OPEN IN SACROCOCCYGEAL PILONIDAL SINUS TREATMENT: A PROSPECTIVE CLINICAL STUDY.

2021 ◽  
pp. 74-75
Author(s):  
Robindera Kour ◽  
Gurpreet Kour ◽  
K.K. Gupta
Keyword(s):  
Quality Of Life ◽  
Wound Healing ◽  
Local Excision ◽  
Pilonidal Sinus ◽  
Wide Local Excision ◽  
Primary Closure ◽  
Open Group ◽  
Limberg Flap ◽  
Complete Wound Healing

Aim:to compare the quality of life and effectiveness of limberg ap vs lay open in sacrococcygeal pilonidal sinus treatment. Methods: This randomized prospective study was carried out in the Government Hospital Sarwal, Jammu, India among 30 patients. Patients were randomized into two groups; group Awith 15 patients was undergone wide local excision followed by limberg ap primary closure while the other group B with 15 patients was undergone wide local excision followed by Lay open ap (healing by Post operatively assessment of healing time and quality of life at 4 and 8 weeks was done.). Results: Mean age of the subject of the limberg ap group and lay open group was 22.42 years and 22.38 years respectively. 90% of the patient's (27 patients) of the present study were males. In limberg ap group 53.3% patient achieved complete wound healing around 20-30 days while in lay open group 60.0% patient achieved complete wound healing around 51-60 days post operatively Conclusions:Excision with primary closure is a better modality than excision with lay open technique in treatment of pilonidal sinus

Neuropathic pain and quality of life after wide local excision and sentinel lymph node biopsy for melanoma

2017 ◽  
Vol 27 (2) ◽  
pp. 121-125 ◽  
Author(s):  
Collette H. Thomson ◽  
Oliver Cassell ◽  
Howard Peach ◽  
Samantha Holloway ◽  
Jennifer Garioch ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Neuropathic Pain ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Local Excision ◽  
Wide Local Excision ◽  
Lymph Node Biopsy ◽  
Node Biopsy

scholarly journals Quality of Life in Hidradenitis Suppurativa: An Update

2021 ◽  
Vol 18 (11) ◽  
pp. 6131
Author(s):  
Pavel V. Chernyshov ◽  
Andrew Y. Finlay ◽  
Lucia Tomas-Aragones ◽  
Francoise Poot ◽  
Francesca Sampogna ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Acne Inversa ◽  
Health Related Quality ◽  
Number Of Patients ◽  
Related Quality ◽  
Health Related ◽  
Positive Effect ◽  
Specific Health

Knowledge on hidradenitis suppurativa/acne inversa (HS) is rapidly increasing. HS has a profound impact on patients and their family life. Several factors, such as comorbidities, unemployment and HS severity, make this impact even more severe. The most widely used instrument to measure this impact is the dermatology-specific DLQI. We also identified six HS-specific health-related quality of life (HRQoL) instruments. Of them, HIDRAdisk, HSIA, HiSQOL and HSQoL-24 are better validated but there is still lack of experience of its use. Several treatment methods showed positive effect on patients’ HRQoL. Surgery remains a method with a substantial positive effect on HRQoL. Several studies confirming a positive effect of adalimumab on the HRQoL of patients with HS were published during the last three years. Data on the influence of several other biologics on HRQoL of HS patients are controversial or based on studies with a small number of patients.

Trends in Hidradenitis Suppurativa Disease Severity and Quality of Life Outcome Measures: A Systematic Review (Preprint)

2021 ◽  
Author(s):  
Jalal Maghfour ◽  
Torunn Elise Sivesind ◽  
Cory A. Dunnick ◽  
Robert Paul Dellavalle
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Disease Severity ◽  
Outcome Measures ◽  
Hidradenitis Suppurativa ◽  
Life Quality ◽  
Clinical Score ◽  
Validity And Reliability ◽  
Patient Reported

BACKGROUND While there has been an increase in the number of randomized, controlled trials (RCTs) evaluating treatment efficacy for HS, instrument measurements of disease severity and quality of life (QoL) are varied, making compilation of data and comparison between studies a challenge for clinicians. OBJECTIVE The aim of this review is to evaluate trends in disease severity scales and patient reported outcome measures used in RCTs assessing treatment interventions among HS patients. METHODS A primary systematic literature review was conducted in August 2020. PubMed/MEDLINE, Embase, Web of Science, and Cochrane databases were used to identify all articles published from January 1964 to July 2020. The study was prospectively registered with PROSPERO (ID: 209582). Twenty-five articles were included in the systematic review. RESULTS Sartorius and modified Sartorius scores (n=8), and Hidradenitis Suppurativa Clinical score (HiSCs) (n=8) were the most commonly used instruments for disease severity. Participants’ pain, followed by Dermatology Life Quality Index (DLQI), were the most common QoL measures used in the reviewed studies. CONCLUSIONS Heterogeneity of data characterizing both the validity and reliability of existing outcome measures hinders interpretation and translation of the results from RCTs into clinical practice. Many of the QoL measures identified were not specific to HS and may not be representative of all factors impacting patients.

scholarly journals Efficacy of adalimumab in moderate to severe hidradenitis suppurativa: Real life data

2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Aikaterini Kyriakou ◽  
Anastasia Trigoni ◽  
Nikiforos Galanis ◽  
Dimitrios Sotiriadis ◽  
Aikaterini Patsatsi
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Therapeutic Potential ◽  
Therapeutic Option ◽  
Real Life ◽  
Life Quality ◽  
Global Assessment Scale ◽  
Friedman's Test ◽  
Adalimumab Treatment

Hidradenitis suppurativa (HS) is a relapsing, inflammatory disease characterized by painful nodules, abscesses, sinuses track formation and scarring. HS has a great impact on patients’ quality of life and its treatment may be really challenging. Adalimumab provides a new therapeutic option for HS. Our aim was to assess the therapeutic potential of adalimumab on patients with HS based on the data from the daily clinical practice of an HS Outpatient Clinic. 19 patients with clinically evident moderate to severe HS, under adalimumab treatment for at least 24 week, participated in this observational, retrospective study. The Hidradenitis Suppurativa Physician’s Global Assessment scale, Modified Santorius scale and Dermatology Life Quality Index (DLQI) at baseline, week 4, week 12 and week 24 were retrieved from the records. Both Modified Santorius score and DLQI were significantly decreased during the weeks of evaluation (Friedman’s test; P < 0.001). The proportion of patients who achieved clinical response was 10.5% (n = 2) at week 4, 42.1% (n = 8) at week 12 and 63.2% (n = 12) at week 24. Treatment with adalimumab was linked with both clinical remission of HS and improvement of patients’ quality of life.

Preliminary Validation of the HS-QoL: A Quality-of-Life Measure for Hidradenitis Suppurativa

2017 ◽  
Vol 22 (2) ◽  
pp. 142-146 ◽  
Author(s):  
Chelsea McLellan ◽  
Mia Sisic ◽  
Hazel H. Oon ◽  
Jerry Tan
Keyword(s):  
Quality Of Life ◽  
Internal Consistency ◽  
Convergent Validity ◽  
Hidradenitis Suppurativa ◽  
Online Survey ◽  
Preliminary Evidence ◽  
Life Measure ◽  
Preliminary Validation ◽  
Excellent Internal Consistency

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with adverse physical and psychosocial impacts. The development of an HS quality-of-life measure, HS-QoL, has been recently described. Objective: This study was designed to validate the HS-QoL. Method: Fifty-five patients with HS from 4 dermatology clinics completed the 30-minute online survey. Item reduction, reliability (internal consistency), and correlation analysis (to assess convergent validity) were conducted. Results: The HS-QoL was reduced from 53 items to 44 items, resulting in a 7-subscale questionnaire. All subscales demonstrated excellent internal consistency, except for the support subscale, which had adequate internal consistency. All 7 HS-QoL subscales were related to other measures of QoL, life satisfaction, and mental health, which demonstrates convergent validity. Conclusion: The 44-item HS-QoL demonstrated strong preliminary evidence of reliability (internal consistency) and convergent validity.

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