Mixtures of Oseltamivir-sensitive and -resistant Pandemic Influenza A/H1N1/2009 Viruses in Immunocompromised Hospitalized Children

2011 ◽  
Vol 30 (7) ◽  
pp. 625-627 ◽  
Author(s):  
Mas Suhaila ◽  
Julian W. Tang ◽  
Hong Kai Lee ◽  
Cui Lin ◽  
Paul A. Tambyah ◽  
...  
PLoS ONE ◽  
2010 ◽  
Vol 5 (12) ◽  
pp. e15173 ◽  
Author(s):  
Dayanand Bagdure ◽  
Donna J. Curtis ◽  
Emily Dobyns ◽  
Mary P. Glodé ◽  
Samuel R. Dominguez

2012 ◽  
Vol 21 (3) ◽  
pp. 254-258 ◽  
Author(s):  
Abdullah F. Owayed ◽  
Entesar H. Husain ◽  
Ahmad Al-Khabaz ◽  
Hanan Y. Al-Qattan ◽  
Nufoud Al-Shammari

2012 ◽  
Vol 27 (4) ◽  
pp. 408 ◽  
Author(s):  
Jeong Hee Ko ◽  
Ji Hye Kim ◽  
Jin Han Kang ◽  
Jong-Hyun Kim ◽  
Byung Wook Eun ◽  
...  

Author(s):  
José Alberto Choreño-Parra ◽  
Luis Armando Jiménez-Álvarez ◽  
Gustavo Ramírez-Martínez ◽  
Alfredo Cruz-Lagunas ◽  
Mahima Thapa ◽  
...  

Abstract The differentiation of influenza and COVID-19 could constitute a diagnostic challenge during the ongoing winter due to their clinical similitude. Thus, novel biomarkers that enable distinguishing both diseases are required. Here, we evaluated whether the surfactant protein D (SP-D), a collectin produced at the alveolar epithelium with known immune properties, was useful to differentiate pandemic influenza A(H1N1) from COVID-19 in critically ill patients. Our results revealed high serum SP-D levels in severe pandemic influenza but not COVID-19 patients. This finding was validated in a separate cohort of mechanically ventilated COVID-19 patients who also showed low plasma SP-D levels. However, plasma SP-D levels did not distinguish seasonal influenza from COVID-19 in mild-to-moderate disease. Finally, we found that high serum SP-D levels were associated with mortality and renal failure among severe pandemic influenza cases. Thus, our studies have identified SP-D as a unique biomarker expressed during severe pandemic influenza but not COVID-19.


2010 ◽  
Vol 16 (S2) ◽  
pp. 1122-1123
Author(s):  
CS Goldsmith ◽  
MG Metcalfe ◽  
W-J Shieh ◽  
DM Blau ◽  
DC Rollin ◽  
...  

Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.


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