Re: “Transient Eyelid Edema Following COVID-19 Vaccination”

The article presents the results of laboratory studies to assess the toxicological parameters of montmorillonite clay from the Pogadaevskoye deposit in the West Kazakhstan region in order to use them as an aluminosilicate sorbent in the composition of feeds that reduce the negative effects of mycotoxins on the body of animals and birds. The relevance of research is associated with the cultivation of healthy and highly productive animals and poultry in order to ensure the food security of the Republic of Kazakhstan.The studies carried out to assess the toxicological parameters of montmorillonite clay in order to use them as an aluminosilicate sorbent in experimental animals (rabbits and white rats) allowed the following results to be obtained: Visual study of the intensity of erythema when exposed to the test substance on the skin of rabbits showed their absence (0 points). The study of the intensity of edema (an increase in the thickness of the skin clutch of rabbits) when exposed to the test substance on the skin of rabbits showed no reaction (0 points). Studies evaluating the irritating effect of the test substances on the mucous membranes of the eyes of rabbits by symptoms of damage showed the absence of hyperemia (0 points). Weak eyelid edema (1 point), the minimum amount of discharge in the corner of the eye (1 point). The results of studies on the classification assessment of the test substance for the severity of the irritant effect on the eyes of rabbits showed that the average total score of the severity of the irritative effect corresponds to 1 point. A comprehensive analysis of the results obtained on the basis of scientific and experimental studies to assess the toxicological indicators of montmorillonite clay from the Pogadaevskoye deposit in relation to irritating effects on the skin and mucous membranes of experimental animals (rabbits) showed their harmlessness.

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EFFECT OF BROMELAIN AND ARNICA COMBINATION ON PERIORBITAL EDEMA AND ECCHYMOSIS IN SEPTORHINOPLASTY

10.22541/au.161166508.85220299/v1 ◽

2021 ◽

Author(s):

ONER SAKALLIOGLU ◽

EMRAH GÜLMEZ ◽

YAVUZ SULTAN SELIM YILDIRIM ◽

HASAN CETINER ◽

SERTAC DUZER ◽

...

Keyword(s):

Topical Administration ◽

Control Group ◽

Study Group ◽

Periorbital Edema ◽

Eyelid Edema ◽

Group 2 ◽

Group 1

Purpose: The aim of this study to investigate the effect of bromelain-arnica gel combination on periorbital edema and ecchymosis seen after open septorhinoplasty. Methods: Sixty patients who performed open septorhinoplasty with osteotomies were included to the study. These patients were allocated into two groups: in group 1, 30 patients as control and in group 2, 30 patients as study group who were treated with topical bromelain-arnica gel after surgery. Scoring of eyelid edema and peroirbital ecchymosis were evaluated on the first, third and seventh postoperative days using scale of 0 to 4 used by observers. Results: We observed that the administration of topical bromelain-arnica gel after surgery was effective clinically and statistically in decreasing the score of both edema and ecchymosis in open septorhinoplasty with ostetomies. In group 2 patients, periorbital edema and ecchymosis scores were significantly lower compared to control group (p < 0.05). Conclusions: Our results support that topical administration of bromelain and arnica gel combination provided both clinically and statistically significant reduction in periorbital edema and ecchymosis following septorhinoplasty.

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The girl with the eyeball tattoo—what the ophthalmologist may expect? Case report and a review of literature

European Journal of Ophthalmology ◽

10.1177/1120672118803855 ◽

2018 ◽

Vol 29 (5) ◽

pp. NP1-NP4 ◽

Cited By ~ 3

Author(s):

Katarzyna Tubek ◽

Tomasz Berus ◽

Robert Leszek

Keyword(s):

Ocular Inflammation ◽

Secondary Glaucoma ◽

Bulbar Conjunctiva ◽

Review Of Literature ◽

Eye Pain ◽

Eyelid Edema ◽

Anterior Lens Capsule ◽

Contralateral Eye ◽

First Time

Introduction: We report a case of patient who underwent bilateral eyeball tattoo procedure for cosmetic purpose complicated with intraocular dye injection which led to ocular inflammation, secondary glaucoma, and cataract. Case description: A 21-year-old female presented to emergency department with severe right eye pain and photophobia 21 days after conjunctival tattooing procedure. Slit-lamp examination revealed right-sided eyelid edema and black deposits of tattoo ink under the bulbar conjunctiva. Dye deposits were also present in anterior chamber, covering corneal endothelium, iris and anterior lens’ capsule. Ocular inflammation and secondary glaucoma were diagnosed. The patient underwent surgical treatment to control ocular inflammation. Intraocular pressure remained stable after Nd:YAG iridotomy and on topical drugs. Moreover, during the follow-up, in contralateral eye, we observed “conjunctival lumps”—local hypersensitivity reaction to the dye, which were asymptomatic to the patient. Conclusion: Eyeball tattooing complications are new challenges that ophthalmologist may have to face nowadays. We also reviewed for the first time possible complications of eyeball tattooing described in available literature.

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Tube Shunt Related Complications of the Orbit

Complications of Glaucoma Surgery ◽

10.1093/oso/9780195382365.003.0068 ◽

2013 ◽

Author(s):

Marc R. Criden

Keyword(s):

Glaucoma Surgery ◽

Shunt Surgery ◽

Ocular Surgery ◽

Significant Treatment ◽

Mechanical Complications ◽

Surface Areas ◽

Eyelid Edema ◽

Shunt Implantation ◽

Orbital Complications ◽

Tube Shunt

Orbital complications during or after glaucoma filtering or tube shunt surgery are relatively rare but may pose a significant treatment challenge or threat to vision. The incidence of complications is highly variable, and transient events may not be reported as frequently as those that persist. A variety of orbital complications occur following glaucoma surgery. Complications may be categorized as mechanical, infectious, neurogenic, or myogenic. However, each complication may be multimodal and fall into more than one category. Mechanical complications are the most frequent type of orbit complication related to glaucoma surgery and more specifically to tube shunt implantation. Mechanical complications include ptosis, lid retraction, strabismus, and proptosis. Several theories address why ptosis may occur after ocular surgery and why it may be either transient or permanent. The levator muscle may be damaged or dehisced by an eyelid speculum, leading to a lid droop. Bridle sutures, which are often used during glaucoma surgery, have also been implicated as they apply counter traction against the superior rectus muscle. Prolonged eyelid edema and local anesthesia have each been more strongly associated with postoperative ptosis. For more information on ptosis, see Chapter 25. Strabismus after tube shunt implantation is most commonly related to either the device itself or to scarring and fibrosis that develop postoperatively. Transient strabismus may be related to swelling or edema of local tissues and may also follow retrobulbar injection. The strabismus is usually incomitant and does not present with a characteristic pattern of deviation; thus, prisms and other nonsurgical treatments are seldom adequate. Although strabismus following tube shunt surgery is usually transient, persistent diplopia may occur. The type of implant, size, location, and material each play a role. Implants with larger surface areas have a higher incidence of motility disturbance due to mass effect. Tube shunt plates that require placement below the rectus muscles risk direct muscle injury or adhesion scarring to the implant. In addition, a pseudo-Brown’s syndrome may be created by a superonasal implant due to interference with the superior oblique muscle function. The bleb that develops around the tube shunt reservoir can also act as a mass.

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Ptosis

Complications of Glaucoma Surgery ◽

10.1093/oso/9780195382365.003.0040 ◽

2013 ◽

Author(s):

Marc R. Criden

Keyword(s):

Neuromuscular Block ◽

Glaucoma Surgery ◽

The Elderly ◽

Contributing Factors ◽

Ocular Surgery ◽

Upper Eyelid ◽

Eyelid Edema ◽

Traction Suture ◽

Susceptible Populations ◽

Levator Aponeurosis

Ptosis of the upper eyelids is a well-known complication of most forms of ocular surgery. The incidence of ptosis following glaucoma surgery is reported to range from 6 to 12%. The etiology has not been entirely established; however, it is believed to be multifactorial, and several contributing factors have been identified. Identification of the etiology is important since this will often dictate the management. The ptosis may be transient, resolving within days, or persistent. The management of acquired ptosis following glaucoma surgery is critical since surgical over correction can expose a filtering bleb and lead to serious complications, including endophthalmitis. Transient ptosis following surgery is more common than persistent ptosis and may recover within 12 to 72 hours. It may be caused by anesthetic, lid edema, or hematoma formation in the eyelid or muscle. A retrobulbar or peribulbar block with lidocaine may affect the levator muscle. Similarly, direct infiltration of the eyelid will block the distal fibers of the oculomotor nerve. The primary factors postulated to cause ptosis include muscle or nerve damage from local block, a superior rectus bridle suture or corneal traction suture, general anesthesia, eyelid edema, traction applied by the speculum, and levator aponeurosis dehiscence. The lid speculum has been identified as a cause of ptosis regardless of the type of ocular surgery. Superior forces are placed on the upper eyelid while a superior bridle suture or corneal traction suture directs forces downward. These opposing forces may cause a stretching or frank dehiscence of the levator aponeurosis. One study specifically looked at the role of the bridle suture and did not find a significant contribution to ptosis development versus those cases that did not use a bridle suture. Rather, lid edema, neuromuscular block, and the lid speculum itself were identified as causative factors. It has been suggested that prolonged eyelid edema leads to disinsertion of the levator aponeurosis in susceptible populations, such as the elderly. This has not been borne out in other studies; however, some of the same factors that cause prolonged edema may also cause persistent ptosis, specifically inflammation.

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REDUCING THE EYELID EDEMA AND ECCHYMOSIS THAT OCCUR AFTER CORRECTIVE RHINOPLASTY

Plastic & Reconstructive Surgery ◽

10.1097/00006534-197205000-00005 ◽

1972 ◽

Vol 49 (5) ◽

pp. 508-512 ◽

Cited By ~ 6

Author(s):

SAMEER I. SHEHADI

Keyword(s):

Eyelid Edema

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Melkersson-Rosenthal Syndrome with Isolated Unilateral Eyelid Edema

Ophthalmic Plastic and Reconstructive Surgery ◽

10.1097/iop.0000000000000088 ◽

2015 ◽

Vol 31 (3) ◽

pp. e70-e77 ◽

Cited By ~ 5

Author(s):

Xi Chen ◽

Frederick A. Jakobiec ◽

Prashant Yadav ◽

Xiang Q Werdich ◽

Aaron Fay

Keyword(s):

Eyelid Edema

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Comparison of Topical 0.05% Levocabastine and 0.1% Lodoxamide in Patients with Allergic Conjunctivitis

European Journal of Ophthalmology ◽

10.1177/112067219800800402 ◽

1998 ◽

Vol 8 (4) ◽

pp. 207-216 ◽

Cited By ~ 12

Author(s):

C. Richard ◽

C. Trinquand ◽

E. Bloch-Michel ◽

F. Favennec ◽

L. Helleboid ◽

...

Keyword(s):

Allergic Conjunctivitis ◽

Ophthalmic Solution ◽

Signs And Symptoms ◽

Serious Adverse Events ◽

Treatment Groups ◽

Self Evaluation ◽

Eyelid Edema ◽

Parallel Group ◽

Clinically Significant ◽

Allergy Symptom

Purpose The aim of the study was to assess the efficacy and safety of 0.05% levocabastine eyedrops (H1 receptor blocker given BID + vehicle BID) compared with 0.1% lodoxamide ophthalmic solution (mast-cell stabilizer instilled QID) in reducing ocular signs and symptoms of allergic conjunctivitis. Methods A randomized, double-masked, parallel-group study was conducted in seven centres in France, in which 93 patients suffering from seasonal or perennial allergic conjunctivitis were randomly allocated to either 0.05% levocabastine (n = 47) or 0.1% lodoxamide (n = 46) in both eyes for a 14-day period. Efficacy was evaluated by subjective (prickling, burning, photophobia, itching) and objective (redness, chemosis, eyelid edema, tearing) sign scores at visits on days 7 and 14, and from data noted daily by the patient in a self-evaluation form. Safety was assessed as tolerance upon instillation and adverse event reports. Results The ocular allergy symptom and sign scores were comparable in the two treatment groups at baseline. With time, statistically and clinically significant reductions (p < 0.001) from baseline were observed for the subjective and objective scores, with no difference between the treatment groups. After the first instillation, signs were alleviated more rapidly in levocabastine-treated patients than in the lodoxamide group (p < 0.001). Overall assessments by the patient and investigator were similar in both groups. No serious adverse events were reported. Conclusions Levocabastine ophthalmic suspension 0.05% (BID) appears to be as effective and safe as lodoxamide 0.1% (QID) in the management of allergic conjunctivitis.

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