Postoperative Course of Pars Flaccida Cholesteatoma Patients With Habitual Sniffing

We reported a rare case of spontaneous frank rupture of a small (4 mm) penetrating aortic ulcer in the ascending aorta resulted in catastrophic bleeding. The ulcer only created a pinhole wound in the adventitia without saccular aneurysms, intramural hematomas, or aortic dissections. Notably, the wound could be directly closed because the aortic wall was intact only 5 mm away from the bleeding site. The postoperative course was uneventful, and the patient was discharged on the 11th postoperative day. After 8 months, follow-up computed tomography showed no abnormality of the aortic wall at the repair site.

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Postoperative Rise of Circulating Mitochondrial DNA Is Associated with Inflammatory Response in Patients following Pancreaticoduodenectomy

European Surgical Research ◽

10.1159/000514661 ◽

2021 ◽

pp. 1-7

Author(s):

Niv Pencovich ◽

Nadav Nevo ◽

Roi Weiser ◽

Ekaterina Bonder ◽

Yoel Bogoch ◽

...

Keyword(s):

Mitochondrial Dna ◽

Inflammatory Response ◽

Delayed Gastric Emptying ◽

Clinical Course ◽

Severe Trauma ◽

Postoperative Fever ◽

Postoperative Course ◽

Cell Counts ◽

White Blood Cell Counts ◽

The Relationship

Introduction: Accumulation of plasma mitochondrial DNA (mtDNA) following severe trauma has been shown to correlate with the development of systemic inflammatory response syndrome (SIRS) and may predict mortality. Our objective was to investigate the relationship between levels of circulatory mtDNA following pancreaticoduodenectomy (PD) and the postoperative course. Methods: Levels of plasma mtDNA were assessed by real-time PCR of the mitochondrial genes ND1 and COX3 in 23 consecutive patients who underwent PD 1 day prior to surgery, within 8 h after surgery, and on postoperative day (POD)1 and POD5. The abundance of mtDNA was assessed relative to preoperative levels and in relation to parameters reflecting the postoperative clinical course. Results: When pooled for all patients, the circulating mtDNA levels were significantly increased after surgery. However, while a significant (at least >2-fold and up to >20-fold) rise was noted in 11 patients, no change in mtDNA levels was noted in the other 12 following surgery. Postoperative rise in circulating mtDNA was associated with an increased rate of postoperative fever until day 5, decreased hemoglobin and albumin levels, and increased white blood cell counts. These patients also suffered from increased rates of delayed gastric emptying. No significant differences were demonstrated in other postoperative parameters. Conclusion: Circulating mtDNA surge is associated with an inflammatory response following PD and may potentially be used as an early marker for postoperative course. Studies of larger patient cohorts are warranted.

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Cardiac calcified amorphous tumor with sustained ventricular tachycardia

Asian Cardiovascular and Thoracic Annals ◽

10.1177/02184923211013999 ◽

2021 ◽

pp. 021849232110139

Author(s):

Fumio Yamana ◽

Keitaro Domae ◽

Yukitoshi Shirakawa ◽

Toshiki Takahashi ◽

Hiroyuki Hao

Keyword(s):

Computed Tomography ◽

Ventricular Tachycardia ◽

Histopathological Examination ◽

Sustained Ventricular Tachycardia ◽

Total Removal ◽

Postoperative Course ◽

Contrast Enhanced ◽

Calcified Amorphous Tumor ◽

Cryo Ablation ◽

Myocardial Border

Cardiac calcified amorphous tumors are rare non-neoplastic intracavitary masses with unknown cause. A 60-year-old man presented with sustained ventricular tachycardia. Transthoracic echocardiography and contrast-enhanced angio-computed tomography demonstrated an expanding 73 × 40 mm sized calcified mass in the left ventricle. He underwent successful total removal of the mass and cryo-ablation at the normal myocardial border. Histopathological examination confirmed a diagnosis of cardiac calcified amorphous tumors. The postoperative course was uneventful, without ventricular tachycardia recurrence. To our knowledge, this is the first reported case of confirmed cardiac calcified amorphous tumors causing ventricular tachycardia and treated by surgical resection combined with cryo-ablation.

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Urrets-Zavalia Syndrome Following Cataract Surgery

Case Reports in Ophthalmology ◽

10.1159/000513959 ◽

2021 ◽

pp. 659-663

Author(s):

Shimon Kurtz ◽

Maayan Fradkin

Keyword(s):

Intraocular Pressure ◽

Case Report ◽

Cataract Surgery ◽

Anterior Chamber ◽

Inflammatory Reaction ◽

Intraocular Lens Implantation ◽

Postoperative Course ◽

Lens Implantation ◽

The Right

We describe a case of Urrets-Zavalia syndrome (UZS) in a healthy 56-year-old woman who underwent femtosecond-assisted phacoemulsification with intraocular lens implantation in both eyes. One month after an uneventful postoperative course in the left eye, the right eye was operated. Dilated pupil which was nonreactive to light appeared on day 21 postoperatively. This was discovered upon examination following anterior chamber inflammatory reaction which occurred 2 weeks following her surgery. Our case report emphasizes the importance and danger in developing UZS even if the reaction in the anterior chamber does not occur immediately after surgery. In addition, the importance of intraocular pressure follow-up in the period after UZS is acknowledged.

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Alkaline phosphatase isoforms in serum after liver allograft surgery

Clinical Chemistry ◽

10.1093/clinchem/40.7.1272 ◽

1994 ◽

Vol 40 (7) ◽

pp. 1272-1277 ◽

Cited By ~ 5

Author(s):

J Randolph-Habecker ◽

J A Lott ◽

R J Tesi

Keyword(s):

Liver Transplantation ◽

Alkaline Phosphatase ◽

Liver Function Tests ◽

Clinical Findings ◽

High Molecular Mass ◽

Reference Ranges ◽

Liver Allograft ◽

Postoperative Course ◽

End Stage Liver Disease ◽

End Stage

Abstract Orthotopic liver transplantation (OLT) is now the only available treatment for end-stage liver disease; the major postoperative complications of OLT are rejection and infection. Fractionation of alkaline phosphatase (ALP) isoforms in serum by isoelectric focusing can be used to identify patients with complications. Reference ranges for liver-function tests (LFT) and liver ALP isoforms were established for post-OLT patients with stable postoperative courses and compared with those of patients with complications. We found canalicular, hepatocyte, and high-molecular-mass ALP to be statistically higher in nearly all patients with complications as compared with patients who had a stable postoperative course; these tests may identify patients requiring a liver biopsy. When used in conjunction with LFT and other clinical findings, ALP isoforms could aid in the monitoring of complications and treatment and in the adjustment of immunosuppressive therapy in stable OLT cases.

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