scholarly journals The mediating and moderating roles of resilience in the relationship between anxiety, depression, and post-traumatic growth among breast cancer patients based on structural equation modeling

Medicine ◽  
2020 ◽  
Vol 99 (50) ◽  
pp. e23273
Author(s):  
Linbo Li ◽  
Yongchao Hou ◽  
Linbo Li ◽  
Yongchao Hou ◽  
Fengying Kang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Structural Equation Modeling ◽  
Cancer Patients ◽  
Structural Equation ◽  
Equation Modeling ◽  
Breast Cancer Patients ◽  
Post Traumatic Growth ◽  
Post Traumatic ◽  
Anxiety Depression ◽  
The Relationship

Post-Traumatic Growth After the Drug-Related Death of a Loved One: Understanding the Influence of Self-Compassion and Hope

2021 ◽  
pp. 106648072110524
Author(s):  
Katharine R. Sperandio ◽  
Daniel Gutierrez ◽  
Meghan Kirk ◽  
Jessica Lopez ◽  
W. Nathaniel Mason
Keyword(s):  
Structural Equation Modeling ◽  
Posttraumatic Growth ◽  
Structural Equation ◽  
Equation Modeling ◽  
Loved One ◽  
Self Compassion ◽  
Post Traumatic Growth ◽  
Meaningful Relationship ◽  
Post Traumatic ◽  
The Relationship

The interaction between self-compassion, hope, and posttraumatic growth (PTG) following the loss of a loved one to a drug related death (DRD) has been largely unexplored in the current literature. This study examines the interaction between the constructs of hope and self-compassion as they impact PTG among those who are in bereavement from a DRD. For the purposes of this study a “loved one” is defined as anyone who had a meaningful relationship with the person who is now deceased. We examined the associations between self-compassion, PTG and hope using structural equation modeling with a sample of 292 individuals who experienced the DRD of a loved one. Our analysis shows that self-compassion serves as a predictor for PTG when operating independently from hope. When the construct of hope is introduced, it serves as a powerful mediator on the relationship between self-compassion and PTG following bereavement by a DRD. These results suggest that the facilitation of the psychospiritual constructs of hope and self-compassion during the counseling process following the loss of a loved one to a DRD can serve to support PTG.

scholarly journals The influence of coping types on post-traumatic growth in patients with primary breast cancer

2020 ◽  
Vol 51 (1) ◽  
pp. 85-91
Author(s):  
Tomomi Fujimoto ◽  
Hitoshi Okamura
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Japanese Version ◽  
Breast Cancer Diagnosis ◽  
Well Being ◽  
Proactive Coping ◽  
Breast Cancer Patients ◽  
Post Traumatic Growth ◽  
Post Traumatic ◽  
Mental Well Being

Abstract Background The physical and mental impacts of breast cancer diagnosis on women are substantial. Several studies have investigated the negative mental health effects of breast cancer. However, in recent years, there has also been growing interest in post-traumatic growth, a positive response to stressful events. Considering positive psychology focuses on such virtues, proactive coping theory was chosen as a theoretical guide. This study investigates how breast cancer patients’ post-traumatic growth is associated with proactive coping and mental well-being. Methods A self-administered questionnaire survey was conducted with 80 breast cancer patients aged 20–70 years attending an outpatient clinic. The survey was conducted using the Posttraumatic Growth Inventory-Japanese version (PTGI-J), Proactive Coping Inventory-Japanese version and the Japanese version of the General Health Questionnaire. Single regression and multiple regression analyses with PTGI-J as the dependent variable were performed. Results The multiple regression analysis extracted proactive coping (P = 0.006), emotional support seeking (P = 0.004) and avoidance coping (P = 0.001) as factors associated with post-traumatic growth in breast cancer patients. Conclusions These results suggest that using proactive coping for conflicts caused by a breast cancer diagnosis and temporary avoidant coping for daily stresses during the treatment process may enhance post-traumatic growth while preventing deterioration in mental well-being. Additionally, seeking emotional support is important for post-traumatic growth.

scholarly journals Association between Type-D Personality and Affective (Anxiety, Depression, Post-traumatic Stress) Symptoms and Maladaptive Coping in Breast Cancer Patients: A Longitudinal Study

2021 ◽  
Vol 17 (1) ◽  
pp. 271-279
Author(s):  
Luigi Grassi ◽  
Rosangela Caruso ◽  
Martino Belvederi Murri ◽  
Richard Fielding ◽  
Wendy Lam ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Psychosocial Distress ◽  
Type D Personality ◽  
Breast Cancer Patients ◽  
Post Traumatic Stress ◽  
Maladaptive Coping ◽  
Type D ◽  
Post Traumatic ◽  
Anxiety Depression

Background: Type-D (distressed) personality has not been prospectively explored for its association with psychosocial distress symptoms in breast cancer patients. Objective: The objective of the study was to test the hypothesis that Type-D personality can be associated with psychosocial distress variables in cancer over a 2-point period (6 month-follow-up). Aims: The aim of the study was to analyze the role of Type-D personality in relation to anxiety, depression, post-traumatic stress symptoms, general distress, and maladaptive coping among cancer patients. Methods: 145 breast cancer patients were assessed within 6 months from diagnosis (T0) and again 6 months later (T1). The Type-D personality Scale, the Hospital Anxiety and Depression Scale, Depression subscale (HAD-D), the Brief Symptom Inventory (BSI-18) Anxiety subscale, the Distress Thermometer (DT), the Post-traumatic Symptoms (PTS) Impact of Event Scale (IES), and the Mini Mental Adjustment to Cancer (Mini-MAC) Anxious Preoccupation and Hopelessness scales were individually administered at T0 and T1. Results: One-quarter of cancer patients met the criteria for Type-D personality, which was stable over the follow-up time. The two main constructs of Type-D personality, namely social inhibition (SI) and negative affectivity (NA), were related to anxiety, depression, PTS, BSI-general distress and maladaptive coping (Mini-MAC anxious preoccupation and hopelessness). In regression analysis, Type-D SI was the most significant factor associated with the above-mentioned psychosocial variables, both at T0 and T1. Conclusion: Likewise other medical disorders (especially cardiology), Type-D personality has been confirmed to be a construct significantly related to psychosocial distress conditions and maladaptive coping that are usually part of assessment and intervention in cancer care. More attention to personality issues is important in oncology.

Measurement of quality of life in women with breast cancer before and after adjuvant chemotherapy: A structural equation modelling

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e11513-e11513
Author(s):  
J. B. Choudhury ◽  
G. Beadle ◽  
K. Mengersen
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Structural Equation ◽  
Self Esteem ◽  
Equation Modeling ◽  
Breast Cancer Patients ◽  
Changes Over Time ◽  
Over Time

e11513 Background: This study examines breast cancer patients’ individual changes in health related quality of life (HRQOL) measures over time and the relationships between these measures within the framework of Structural equation modeling (SEM). Methods: One hundred and fifty five Australian women with breast cancer were asked to complete the Functional Assessment of Cancer Therapy Breast, Version 4 (FACT-B) pre- and post-chemotherapy as measures of HRQOL. In SEM, growth curve modelling was required for the estimation of individual differences in developmental changes of HRQOL scales over time. A growth mixture model was also used for identifying the cross-group differences in the pattern of changes in a given population over time. Results: Reliability and validity of the FACT-G including the fatigue subscale and breast cancer subscale for evaluating Australian breast cancer patients was determined to be sufficient for research purposes. After adjustment for covariates, two subgroups of women were identified with respect of patterns of response, representing largely increasing and decreasing trends in HRQOL respectively. In the former group, on average 85% of breast cancer women reported changes over time with respect to individual HRQOL measures and 78% reported such changes with respect to combined HRQOL Scores. A small group of women reported changes with respect to HRQOL measures in the decreasing group. The greatest contribution to variation in HRQOL measures was in the breast cancer subscale for both individual and combined scores. Subsequent factor analysis of the breast cancer subscale revealed that with one exception, all items loaded onto three separate factors described as self-esteem, physical and psychological. The latter two improved over time, but self- esteem was largely unchanged. Conclusions: The study presents a technique that allows us to identify potential subgroups of study subjects that experience different trajectories of responses. The results of this study provide greater insight into HRQOL changes over time and can help to plan interventions in a better way, ultimately contributing to improvement in HRQOL of women with breast cancer. No significant financial relationships to disclose.

scholarly journals Mediator Roles of Social Support and Hope in the Relationship Between Body Image Distress and Resilience in Breast Cancer Patients Undergoing Treatment: A Modeling Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Hsin-Tien Hsu ◽  
Chiung-Hui Juan ◽  
Jyu-Lin Chen ◽  
Hsiu-Fen Hsieh
Keyword(s):  
Breast Cancer ◽  
Social Support ◽  
Body Image ◽  
Cancer Patients ◽  
Equation Modeling ◽  
Breast Cancer Patients ◽  
Convenience Sample ◽  
Mediating Role ◽  
The Impact ◽  
The Relationship

Breast cancer and its treatment are particularly distressing for patients because of their potential impacts on body image. The most difficult phase of cancer treatment is usually the first year after a diagnosis. Cancer patients with strong resilience have the positive attitude, internal strength and external resources needed to cope with the disease and its treatment. This cross-sectional study investigated the mediator roles of hope and social support in the association between body image distress and resilience. A structured questionnaire was used to collect data for a convenience sample of 141 breast cancer patients undergoing treatment in southern Taiwan. Structural equation modeling was used for data analysis. The results showed that the final model had a good fit to the data and accounted for 51% of the total variance in resilience. The model of multiple parallel mediators of resilience revealed that hope and social support had mediator roles in the effect of body image distress on resilience. Hope had an important partial mediating role in the association between body image distress and resilience. Social support also had a partial mediating role in the relationship between body image distress and resilience. Social support did not directly affect resilience and indirectly affected resilience through hope. Psychosocial interventions aimed at reducing the impact of body image distress and increasing resilience in breast cancer patients should focus on cultivating hope and increasing social support, particularly support from family members and health professionals.

scholarly journals The contribution of dietary and plasma folate and cobalamin to levels of angiopoietin-1, angiopoietin-2 and Tie-2 receptors depend on vascular endothelial growth factor status of primary breast cancer patients

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Saeed Pirouzpanah ◽  
Parisa Varshosaz ◽  
Ashraf Fakhrjou ◽  
Vahid Montazeri
Keyword(s):  
Breast Cancer ◽  
Folic Acid ◽  
Cancer Patients ◽  
Structural Equation ◽  
Equation Modeling ◽  
Vascular Endothelial ◽  
Breast Cancer Patients ◽  
Dietary Folate ◽  
Endothelial Growth Factor

Abstract The aim of this study was to determine the association of dietary folate and cobalamin with plasma levels of Angiopoietins (ANG), vascular endothelial growth factor-C (VEGF-C) and tyrosine kinase receptor-2 (Tie-2) of primary breast cancer patients. Women (n = 177), aged 30 to 75 years diagnosed with breast cancer were recruited from an ongoing case series study. Dietary intake of nutrients was estimated by using a validated food frequency questionnaire. Enzyme-linked immunosorbent assay was applied to measure biomarkers. MCF-7 cell cultures were supplemented with folic acid (0–40 μM) for 24 h to measure cell viability and fold change of expression by the real-time reverse transcriptase-polymerase chain reaction. Structural equation modeling was applied to analyze the structural relationships between the measured variables of nutrients and Angiopoietins. Dietary intake of folate and cobalamin showed a significant inverse correlation with plasma ANG-1 and ANG-2 (P < 0.05), particularly in subjects with estrogen-receptor positive tumors or low plasma VEGF-C. Plasma folate was positively associated with the ratio of ANG-1/ANG-2 (P < 0.05). Residual intake levels of total cobalamin were inversely associated with plasma ANG-1 when plasma stratum of VEGF-C was high (P < 0.05). Structural equation modeling identified a significant inverse contribution of folate profiles on the latent variable of Angiopoietins (coefficient β = −0.99, P < 0.05). Folic acid treatment resulted in dose-dependent down-regulations on ANGPT1 and ANGPT1/ANGPT2 ratio but VEGF and ANGPT2/VEGF were upregulated at folic acid >20 μM. Studying the contributing role of dietary folate to pro-angiogenic biomarkers in breast cancer patients can infer the preventive role of folate in the ANGs/VEGF-C-dependent cascade of tumor metastasis. By contrast, high concentrations of folic acid in vitro supported VEGF-C-dependent ANGPT2 overexpression might potentiate micro-lymphatic vessel development to support malignant cell dissemination.

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