Sarcoidosis afflicts the central nervous system more frequently than
previously believed. Neurological symptoms are present in roughly a half of
patients, and depend of the location in central nervous system. The
probability of spontaneous regression is significantly less when compared to
other forms of sarcoidosis, which means that the proper diagnosis and
treatment is paramount. Even when properly treated, functional defects are
not uncommon. Majority of these patients require immunomodulating drugs and
continuous follow-up. New immunomodulating drugs, especially biological
agents, have shown to be significantly more effective, with fewer side
effects, and are important when corticosteroids could not be applied. Less
invasive methods, such as cerebrospinal analysis, help greatly in the
diagnostics procedure, and require further research and improvement
Spontaneous regression of central nervous system posttransplant lymphoproliferative disease
