Relevance of Methane and Carbon dioxide Evaluation in Breath Tests for Carbohydrate Malabsorption in A Paediatric Cohort

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Karin Hammer ◽  
Hana Hasanagic ◽  
Nima Memaran ◽  
Wolf-Dietrich Huber ◽  
Johann Hammer
1994 ◽  
Vol 29 (9) ◽  
pp. 826-832 ◽  
Author(s):  
J. J. Rumessen ◽  
I. Nordgaard-Andersen ◽  
E. Gudmand-Høyer

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Christof Schneider ◽  
Klaus D. Wutzke ◽  
Jan Däbritz

Abstract Carbohydrate malabsorption and subsequent gastrointestinal symptoms are a common clinical problem in pediatrics. Hydrogen (H2) and methane (CH4) breath tests are a cheap and non-invasive procedure for diagnosing fructose and lactose malabsorption (FM/LM) but test accuracy and reliability as well as the impact of non-hydrogen producers (NHP) is unclear. CH4 breath tests (MBT), blood sugar tests (BST) and clinical symptoms were compared with H2 breath tests (HBT) for FM/LM. 187/82 tests were performed in children (2 to 18 years) with unclear chronic/recurrent abdominal pain and suspected FM/LM. In FM and LM, we found a significant correlation between HBT and MBT/BST. In LM, MBT differentiated most of the patients correctly and BST might be used as an exclusion test. However, additional MBT and BST had no diagnostic advantage in FM. NHP still remain a group of patients, which cannot be identified using the recommended CH4 cut-off values in FM or LM. Reported symptoms during breath tests are not a reliable method to diagnose FM/LM. Overall a combined test approach might help in diagnosing children with suspected carbohydrate malabsorption.


2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Jan Däbritz ◽  
Michael Mühlbauer ◽  
Dirk Domagk ◽  
Nicole Voos ◽  
Geraldine Henneböhl ◽  
...  

Author(s):  
K. C. Tsou ◽  
J. Morris ◽  
P. Shawaluk ◽  
B. Stuck ◽  
E. Beatrice

While much is known regarding the effect of lasers on the retina, little study has been done on the effect of lasers on cornea, because of the limitation of the size of the material. Using a combination of electron microscope and several newly developed cytochemical methods, the effect of laser can now be studied on eye for the purpose of correlating functional and morphological damage. The present paper illustrates such study with CO2 laser on Rhesus monkey.


Author(s):  
Charles TurnbiLL ◽  
Delbert E. Philpott

The advent of the scanning electron microscope (SCEM) has renewed interest in preparing specimens by avoiding the forces of surface tension. The present method of freeze drying by Boyde and Barger (1969) and Small and Marszalek (1969) does prevent surface tension but ice crystal formation and time required for pumping out the specimen to dryness has discouraged us. We believe an attractive alternative to freeze drying is the critical point method originated by Anderson (1951; for electron microscopy. He avoided surface tension effects during drying by first exchanging the specimen water with alcohol, amy L acetate and then with carbon dioxide. He then selected a specific temperature (36.5°C) and pressure (72 Atm.) at which carbon dioxide would pass from the liquid to the gaseous phase without the effect of surface tension This combination of temperature and, pressure is known as the "critical point" of the Liquid.


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