Spontaneous HIV controllers might be the key to prevent accelerated immunosenescence of effector CD8+ T cells

AIDS ◽  
2019 ◽  
Vol 33 (14) ◽  
pp. 2253-2255
Author(s):  
Tetsuo Tsukamoto
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Hiv Controllers

scholarly journals Immune Activation and HIV-Specific CD8+ T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers

2016 ◽  
Vol 32 (8) ◽  
pp. 791-800 ◽  
Author(s):  
Anupama Ganesh ◽  
Donna Lemongello ◽  
Evelyn Lee ◽  
Julia Peterson ◽  
Bridget E. McLaughlin ◽  
...  
Keyword(s):  
T Cells ◽  
Cerebrospinal Fluid ◽  
Cd8 T Cells ◽  
Immune Activation ◽  
Hiv Controllers

scholarly journals Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses

2009 ◽  
Vol 182 (12) ◽  
pp. 7828-7837 ◽  
Author(s):  
Asier Sáez-Cirión ◽  
Martine Sinet ◽  
So Youn Shin ◽  
Alejandra Urrutia ◽  
Pierre Versmisse ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
Cd8 T Cells ◽  
T Cell Responses ◽  
Cd8 T Cell ◽  
Cell Responses ◽  
Hiv Controllers

scholarly journals A Human Immunodeficiency Virus Controller With a Large Population of CD4+CD8+ Double-Positive T Cells

2015 ◽  
Vol 2 (2) ◽  
Author(s):  
Christine M. Durand ◽  
Robert W. Buckheit ◽  
Maria Salgado ◽  
Christopher W. Pohlmeyer ◽  
Victoria E. Walker-Sperling ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cells ◽  
Antiretroviral Therapy ◽  
Cd8 T Cells ◽  
Large Population ◽  
Double Positive ◽  
Immunodeficiency Virus ◽  
Strong Antiviral Activity ◽  
Hiv Controllers ◽  
Hiv 1

Abstract Human immunodeficiency virus (HIV) controllers are patients who control viral replication without antiretroviral therapy. We present the case of an HIV controller who had CD4 and CD8 coexpressed on 40% of his T cells. Although a recent study found that double-positive T cells had superior antiviral capacity in HIV-1 controllers, in this case, the CD4+CD8+ T cells did not have strong antiviral activity.

scholarly journals Potential Role for HIV-Specific CD38−/HLA-DR+ CD8+ T Cells in Viral Suppression and Cytotoxicity in HIV Controllers

PLoS ONE ◽  
2014 ◽  
Vol 9 (7) ◽  
pp. e101920 ◽  
Author(s):  
Stéphane Hua ◽  
Camille Lécuroux ◽  
Asier Sáez-Cirión ◽  
Gianfranco Pancino ◽  
Isabelle Girault ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Viral Suppression ◽  
Potential Role ◽  
Hla Dr ◽  
Hiv Controllers

scholarly journals The potential role of HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppressive activity and cytotoxicity in HIV controllers

2014 ◽  
Vol 14 (S2) ◽  
Author(s):  
Stéphane Hua ◽  
Camille Lecuroux ◽  
Asier Saez-Cirion ◽  
Gianfranco Pancino ◽  
Isabelle Girault ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Potential Role ◽  
Suppressive Activity ◽  
Hla Dr ◽  
Hiv Controllers

scholarly journals The proportion of CD57+ cells among effector CD8+ T cells is lower in HIV controllers compared with antiretroviral therapy-treated patients

AIDS ◽  
2019 ◽  
Vol 33 (14) ◽  
pp. 2137-2147 ◽  
Author(s):  
Soledad Henriquez ◽  
Camille Lécuroux ◽  
Marie Bitu ◽  
Véronique Avettand-Fenoel ◽  
Françoise Churaqui ◽  
...  
Keyword(s):  
T Cells ◽  
Antiretroviral Therapy ◽  
Cd8 T Cells ◽  
Hiv Controllers

scholarly journals NKG2D Expression on HIV-Specific CD8+ T cells Is Reduced in Viremic HIV-1–Infected Patients but Maintained in HIV Controllers

2013 ◽  
Vol 62 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Camille Lecuroux ◽  
Asier Saez-Cirion ◽  
Nicolas Noel ◽  
Lilia Ben-Lamine ◽  
Isabelle Girault ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Nkg2d Expression ◽  
Hiv Controllers ◽  
Hiv 1

Author response for "4‐1BB costimulation promotes bystander activation of human CD8 T cells"

2020 ◽  
Author(s):  
Manuel Reithofer ◽  
Sandra Rosskopf ◽  
Judith Leitner ◽  
Claire Battin ◽  
Barbara Bohle ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Author Response ◽  
Bystander Activation
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