Mesh Complication Rates Following Pelvic Radiation Therapy in Women With History of Synthetic Midurethral Sling Implantation

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Caitlyn E. Painter ◽  
Julia Geynisman-Tan ◽  
Navendu Samant ◽  
Debbie Postlethwaite ◽  
Olga Ramm
Keyword(s):  
Radiation Therapy ◽  
Midurethral Sling ◽  
Complication Rates ◽  
Pelvic Radiation ◽  
Mesh Complication ◽  
History Of

MP89-13 ONABOTULINUMTOXIN A IN PATIENTS WITH A HISTORY OF PRIOR PELVIC RADIATION THERAPY

2015 ◽  
Vol 193 (4S) ◽  
Author(s):  
David Flores ◽  
Stephen Mock ◽  
Joshua Broghammer ◽  
Tomas Griebling ◽  
Roger Dmochowski ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Pelvic Radiation ◽  
Onabotulinumtoxin A ◽  
History Of

Correlation of Smoking History and Other Patient Characteristics With Major Complications of Pelvic Radiation Therapy for Cervical Cancer

2002 ◽  
Vol 20 (17) ◽  
pp. 3651-3657 ◽  
Author(s):  
Patricia J. Eifel ◽  
Anuja Jhingran ◽  
Diane C. Bodurka ◽  
Charles Levenback ◽  
Howard Thames
Keyword(s):  
Radiation Therapy ◽  
Small Bowel ◽  
Patient Characteristics ◽  
Hazard Ratio ◽  
Smoking History ◽  
Complication Rates ◽  
Heavy Smoking ◽  
Gastrointestinal Complications ◽  
Pelvic Radiation ◽  
Increased Risk

PURPOSE: The purpose of this study was to identify patient-related factors that influence the risk of serious late complications of pelvic radiation therapy. PATIENTS AND METHODS: The records of 3,489 patients treated with radiation therapy for International Federation of Gynecology and Obstetrics stage I or II carcinoma of the cervix were reviewed for information about patient characteristics, treatment details, and outcomes. Any complication occurring or persisting more than 3 months after treatment that required hospitalization, transfusion, or an operation or caused severe symptoms or the patient’s death was considered a major late complication. Complication rates were calculated actuarially. The median duration of follow-up was 85 months, and 99% of patients were followed for at least 3 years or until they died. RESULTS: Heavy smoking was the strongest independent predictor of overall complications (multivariate hazard ratio, 2.30; 95% confidence interval [CI], 1.84 to 2.87). The most striking influence of smoking was on the incidence of small bowel complications (hazard ratio for smokers of one or more packs per day, 3.25; 95% CI, 2.21 to 4.78). Hispanics had a significantly lower rate of small bowel complications than whites, and blacks had higher rates of bladder and rectal complications than whites. Thin women had an increased risk of gastrointestinal complications, and obese women were more likely to have serious bladder complications. CONCLUSION: Complications of pelvic radiation therapy are strongly correlated with smoking, race, and other patient characteristics. These factors should be considered before the results of clinical studies are generalized to different cultural and racial groups.

The evolving role of pelvic radiation therapy

2003 ◽  
Vol 13 (2) ◽  
pp. 109-120 ◽  
Author(s):  
Terence Roberts ◽  
Mack Roach
Keyword(s):  
Radiation Therapy ◽  
Pelvic Radiation

Secondary cavernous hemangioma of urinary bladder following pelvic radiation therapy: a case report

2015 ◽  
Vol 36 (1) ◽  
pp. 112
Author(s):  
Jun-jie ZHAO ◽  
Bo YANG ◽  
Zhen-sheng ZHANG ◽  
Yang WANG ◽  
Ying-hao SUN ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Case Report ◽  
Urinary Bladder ◽  
Cavernous Hemangioma ◽  
Pelvic Radiation

The Effect of Obesity, Bariatric Surgery, and Operative Time on Abdominal Body Contouring Outcomes

2021 ◽  
Author(s):  
Vasileios Vasilakis ◽  
Jeffrey L Lisiecki ◽  
Bill G Kortesis ◽  
Gaurav Bharti ◽  
Joseph P Hunstad
Keyword(s):  
Bariatric Surgery ◽  
Operative Time ◽  
Univariate Analysis ◽  
Body Contouring ◽  
Individual Risk ◽  
Wound Complications ◽  
Complication Rates ◽  
Procedure Time ◽  
Body Contouring Surgery ◽  
History Of

Abstract Background Abdominal body contouring procedures are associated with the highest rates of complications among all aesthetic procedures. Patient selection and optimization of surgical variables are crucial in reducing morbidity and complications. Objectives The purpose of this single-institution study was to assess complication rates, and to evaluate BMI, operative time, and history of bariatric surgery as individual risk factors in abdominal body contouring surgery. Methods A retrospective chart review was performed of all patients who underwent abdominoplasty, circumferential lower body lift, fleur-de-lis panniculectomy (FDL), and circumferential FDL between August 2014 and February 2020. Endpoints were the incidence of venous thromboembolism, bleeding events, seroma, infection, wound complications, and reoperations. Univariate statistical analysis and multivariate logistic regressions were performed. Covariates in the multivariate logistic regression were BMI, procedure time, and history of bariatric surgery. Results A total of 632 patients were included in the study. Univariate analysis revealed that longer procedure time was associated with infection (P = 0.0008), seroma (P = 0.002), necrosis/dehiscence (P = 0.01), and reoperation (P = 0.002). These associations persisted following multivariate analyses. There was a trend toward history of bariatric surgery being associated with minor reoperation (P = 0.054). No significant increase in the incidence of major reoperation was found in association with overweight or obese patient habitus, history of bariatric surgery, or prolonged procedure time. BMI was not found to be an individual risk factor for morbidity in this patient population. Conclusions In abdominal body contouring surgery, surgery lasting longer than 6 hours is associated with higher incidence of seroma and infectious complications, as well as higher rates of minor reoperation. Level of Evidence: 4

scholarly journals Exceeding Radiation Dose to Volume Parameters for the Proximal Airways with Stereotactic Body Radiation Therapy Is More Likely for Ultracentral Lung Tumors and Associated with Worse Outcome

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3463
Author(s):  
Mark Farrugia ◽  
Sung Jun Ma ◽  
Mark Hennon ◽  
Chukwumere Nwogu ◽  
Elisabeth Dexter ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Propensity Score ◽  
Stereotactic Body Radiation Therapy ◽  
Performance Status ◽  
Bronchial Tree ◽  
Lung Tumors ◽  
Gender Performance ◽  
Dose Fractionation ◽  
Stereotactic Body Radiation ◽  
History Of

The preferred radiotherapeutic approach for central (CLT) and ultracentral (UCLT) lung tumors is unclear. We assessed the toxicity and outcomes of patients with CLT and UCLT who underwent definitive five-fraction stereotactic body radiation therapy (SBRT). We reviewed the charts of patients with either CLT or UCLT managed with SBRT from June 2010–April 2019. CLT were defined as gross tumor volume (GTV) within 2 cm of either the proximal bronchial tree, trachea, mediastinum, aorta, or spinal cord. UCLT were defined as GTV abutting any of these structures. Propensity score matching was performed for gender, performance status, and history of prior lung cancer. Within this cohort of 83 patients, 43 (51.8%) patients had UCLT. The median patient age was 73.1 years with a median follow up of 29.9 months. The two most common dose fractionation schemes were 5000 cGy (44.6%) and 5500 cGy (42.2%) in five fractions. Multivariate analysis revealed UCLT to be associated with worse overall survival (OS) (HR = 1.9, p = 0.02) but not time to progression (TTP). Using propensity score match pairing, UCLT correlated with reduced non-cancer associated survival (p = 0.049) and OS (p = 0.03), but not TTP. Within the matched cohort, dosimetric study found exceeding a D4cc of 18 Gy to either the proximal bronchus (HR = 3.9, p = 0.007) or trachea (HR = 4.0, p = 0.02) was correlated with worse non-cancer associated survival. In patients undergoing five fraction SBRT, UCLT location was associated with worse non-cancer associated survival and OS, which could be secondary to excessive D4cc dose to the proximal airways.

A Call to Define Stereotactic Radiosurgery

Neurosurgery ◽  
2004 ◽  
Vol 55 (6) ◽  
pp. 1371-1373 ◽  
Author(s):  
Bruce E. Pollock ◽  
L Dade Lunsford
Keyword(s):  
Radiation Therapy ◽  
Stereotactic Radiosurgery ◽  
Single Session ◽  
Short History ◽  
Effective Radiation Dose ◽  
The Past ◽  
Radiation Delivery ◽  
History Of ◽  
Effective Radiation ◽  
And Training

Abstract STEREOTACTIC RADIOSURGERY IS the single-session, precise delivery of a therapeutically effective radiation dose to an imaging-defined target. Conceived and developed during the past 5 decades, stereotactic radiosurgery has involved significant advances, which have improved patient outcomes and made it a critical component of modern neurosurgical practice and training. In this article, a short history of stereotactic surgery and radiosurgery are presented, and radiosurgery is contrasted to radiation therapy. Adherence to accepted, descriptive terms in defining stereotactic radiosurgery and radiation therapy permits a clear distinction among the results of the different radiation delivery techniques for patients, physicians, and other interested parties.

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