scholarly journals Experimental reduction in dietary omega-3 polyunsaturated fatty acids depresses sperm competitiveness

2014 ◽  
Vol 10 (9) ◽  
pp. 20140623 ◽  
Author(s):  
Md. Moshiur Rahman ◽  
Clelia Gasparini ◽  
Giovanni M. Turchini ◽  
Jonathan P. Evans
Keyword(s):  
Fatty Acids ◽  
Sexual Selection ◽  
Polyunsaturated Fatty Acids ◽  
Dietary Intake ◽  
Poecilia Reticulata ◽  
Reproductive Fitness ◽  
Omega 3 ◽  
Adequate Intake ◽  
Abundant Evidence ◽  
Long Chain

The health benefits of diets containing rich sources of long-chain omega-3 polyunsaturated fatty acids (n-3 LC-PUFA) are well documented and include reductions in the risk of several diseases typical of Western societies. The dietary intake of n-3 LC-PUFA has also been linked to fertility, and there is abundant evidence that a range of ejaculate traits linked to fertility in humans, livestock and other animals depend on an adequate intake of n-3 LC-PUFA from dietary sources. However, relatively few studies have explored how n-3 LC-PUFA influence reproductive fitness, particularly in the context of sexual selection. Here, we show that experimental reduction in the level of n-3 LC-PUFA in the diet of guppies ( Poecilia reticulata ) depresses a male's share of paternity when sperm compete for fertilization, confirming that the currently observed trend for reduced n-3 LC-PUFA in western diets has important implications for individual reproductive fitness.

scholarly journals Serum level changes of long chain-polyunsaturated fatty acids in patients undergoing periodontal therapy combined with one year of omega-3 supplementation: a pilot randomized clinical trial

2014 ◽  
Vol 44 (4) ◽  
pp. 169 ◽  
Author(s):  
Gisele Lago Martinez ◽  
Josely Correa Koury ◽  
Marcela Anjos Martins ◽  
Fernanda Nogueira ◽  
Ricardo Guimarães Fischer ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Fatty Acids ◽  
Serum Level ◽  
Polyunsaturated Fatty Acids ◽  
Randomized Clinical Trial ◽  
Periodontal Therapy ◽  
Omega 3 ◽  
One Year ◽  
Long Chain

scholarly journals Positive Associations of Dietary Marine Omega-3 Polyunsaturated Fatty Acids with Lung Function: A Meta-analysis (P18-087-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Bonnie Patchen ◽  
Jiayi Xu ◽  
R Graham Barr ◽  
Ester van Eekelen ◽  
Josee Dupuis ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lung Function ◽  
Polyunsaturated Fatty Acids ◽  
Dietary Intake ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Fish Intake ◽  
Omega 3 ◽  
Black And White ◽  
Former Smokers

Abstract Objectives Our previous study found positive associations between plasma levels of the omega-3 polyunsaturated fatty acids (n-3 PUFAs), specifically docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA), and lung function, especially in current smokers. Given that plasma n-3 PUFA concentrations are driven by dietary intake, we extended our prior findings to a larger sample by studying dietary n-3 PUFAs, including DHA, DPA, eicosapentanoic acid (EPA), and alpha-linolenic acid (ALA), and fish intake. Methods Nine cohorts from the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (N = 37,077 black and white participants) contributed dietary intake and lung function data. In each cohort and each ancestry, separately, associations of dietary n-3 PUFA/fish intake with lung function were estimated in linear regression models. Models were extended to test for n-3 PUFA/fish × smoking status interaction. Fixed-effects meta-analysis was used to generate summarized effect estimates across the cohorts and ancestries. Results Dietary DPA, DHA, EPA, and fish intake were positively associated with forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). ALA had little to no association with these lung function parameters. Associations were similar for black and white participants, and consistent in direction and magnitude across most cohorts. For all participants, 1 standard deviation (SD) higher intake of DPA (∼30 mg/d), DHA (∼200 mg/d), and EPA (∼150 mg/d) were associated with 12–16 mL higher FEV1 and 10–15 mL higher FVC. The effect estimates for fish were in the same direction but smaller in magnitude. Smoking modified the associations of DHA and EPA with FEV1 and FVC; 1 SD higher intake of DHA and EPA were associated with 28–32 mL higher FEV1 and 24–25 mL higher FVC in current smokers, 17–21 mL higher FEV1 and 7–12 mL higher FVC in former smokers, and little to no association in never smokers. Conclusions Dietary DHA, DPA, and EPA, but not ALA, are positively associated with FEV1 and FVC, corroborating our previous findings for plasma n-3 PUFAs. This large cross-sectional meta-analysis shows that diets rich in marine n-3 PUFAs are associated with higher lung function, especially for current and former smokers. Funding Sources National Institutes of Health, NHLBI and NIDDK.

scholarly journals Seawater Culture Increases Omega-3 Long-Chain Polyunsaturated Fatty Acids (N-3 LC-PUFA) Levels in Japanese Sea Bass (Lateolabrax japonicus), Probably by Upregulating Elovl5

Animals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1681
Author(s):  
Xiaojing Dong ◽  
Jianqiao Wang ◽  
Peng Ji ◽  
Longsheng Sun ◽  
Shuyan Miao ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Sea Bass ◽  
Transcript Abundance ◽  
Omega 3 ◽  
Freshwater Pond ◽  
Cultured Fish ◽  
Long Chain ◽  
Japanese Sea Bass

The fatty acid compositions of the fish muscle and liver are substantially affected by rearing environment. However, the mechanisms underlying this effect have not been thoroughly described. In this study, we investigated the effects of different culture patterns, i.e., marine cage culture and freshwater pond culture, on long-chain polyunsaturated fatty acids (LC-PUFA) biosynthesis in an aquaculturally important fish, the Japanese sea bass (Lateolabrax japonicus). Fish were obtained from two commercial farms in the Guangdong province, one of which raises Japanese sea bass in freshwater, while the other cultures sea bass in marine cages. Fish were fed the same commercial diet. We found that omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) levels in the livers and muscles of the marine cage cultured fish were significantly higher than those in the livers and muscles of the freshwater pond cultured fish. Quantitative real-time PCRs indicated that fatty acid desaturase 2 (FADS2) transcript abundance was significantly lower in the livers of the marine cage reared fish as compared to the freshwater pond reared fish, but that fatty acid elongase 5 (Elovl5) transcript abundance was significantly higher. Consistent with this, two of the 28 CpG loci in the FADS2 promoter region were heavily methylated in the marine cage cultured fish, but were only slightly methylated in freshwater pond cultured fish (n = 5 per group). Although the Elovl5 promoter was less methylated in the marine cage reared fish as compared to the freshwater pond reared fish, this difference was not significant. Thus, our results might indicate that Elovl5, not FADS2, plays an important role in the enhancing LC-PUFA synthesis in marine cage cultures.

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