scholarly journals Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck

2018 ◽  
Vol 285 (1888) ◽  
pp. 20180991 ◽  
Author(s):  
Patrik G. Flammer ◽  
Simon Dellicour ◽  
Stephen G. Preston ◽  
Dirk Rieger ◽  
Sylvia Warren ◽  
...  

Throughout history, humans have been afflicted by parasitic worms, and eggs are readily detected in archaeological deposits. This study integrated parasitological and ancient DNA methods with a large sample set dating between Neolithic and Early Modern periods to explore the utility of molecular archaeoparasitology as a new approach to study the past. Molecular analyses provided unequivocal species-level parasite identification and revealed location-specific epidemiological signatures. Faecal–oral transmitted nematodes ( Ascaris lumbricoides and Trichuris trichiura ) were ubiquitous across time and space. By contrast, high numbers of food-associated cestodes ( Diphyllobothrium latum and Taenia saginata ) were restricted to medieval Lübeck. The presence of these cestodes and changes in their prevalence at approximately 1300 CE indicate substantial alterations in diet or parasite availability. Trichuris trichiura ITS-1 sequences grouped into two clades; one ubiquitous and one restricted to medieval Lübeck and Bristol. The high sequence diversity of T.t .ITS-1 detected in Lübeck is consistent with its importance as a Hanseatic trading centre. Collectively, these results introduce molecular archaeoparasitology as an artefact-independent source of historical evidence.

2017 ◽  
Vol 21 (2) ◽  
pp. 193-202 ◽  
Author(s):  
ALEXANDER BERGS ◽  
THOMAS HOFFMANN

What do we know about the past? For at least some languages, we have textual (or archaeological) evidence from various periods – beyond that, there is only reconstruction. But even when we have some textual evidence, what does it tell us? The answer to this question crucially depends on the way we approach the question: we can treat texts as decontextualized, linguistic evidence, as Neogrammarian or Structuralist studies have done (see McMahon 1994: 17–32). Such an approach already allows us to discover important generalizations about the linguistic state of affairs of a particular language or historical period. Using decontextualized historical evidence, for example, we can already ascertain with a high degree of certainty that in Old English voiced and voiceless fricatives were allophones, rather than phonemes, that there was nodo-periphrasis in Middle English, and that in Early Modern English there was some variability between third-person singular present tense {-s} and {-th} – just as we know that present-day Japanese and Korean use postpositions, rather than prepositions.


2021 ◽  
Vol 52 (1) ◽  
pp. 77-103
Author(s):  
S. Mohammad Mozaffari ◽  
Jeremy J. Drake

The historical evidence from the past two millennia show two problems concerning the star Algol (β Per): First, a critical variation in its brightness from a magnitude m ~ 2 in (1) Ptolemy’s Almagest (2nd century AD) and reported by (2) al-Ṣūfī (10th ct.) through its diminution to m = 4 in (3) the star catalog prepared by the Persian astronomers in service of the Yuan dynasty of China in the 13th ct. to becoming brighter, m = 3, as reported by (4) Ibn al-Shāṭir (14th ct.) and (5) Tycho Brahe (16th ct.). In the early modern period, it returned back to m ~ 2, as reported, for example, by Hevelius and Flamsteed (17th ct.), before the discovery of its periodic variability in 1783. Second, al-Ṣūfī reports it as a red star. We present detailed analyses of the sources (3) and (4) for the test of their accuracy and reliability. Our conservative hypothesis concerning the first problem is that the past astronomers observed the star at various phases of its 3-day period of variability. We reject the reddening to have arisen from the extinction due to either the Earth’s atmosphere or an interstellar medium. For resolving both problems, we instead speculate on astrophysical explanations for the observations. These are: copious dust produced as a result of arrested coronal mass ejections or pulverized planetary debris that resides close to the central binary before being dispersed; and a much-enhanced accretion rate that lead Algol into a W Ser-like state in which the primary was enveloped in an inflated accretion disk. We draw an analogy between the dimming of Algol and the recent dimming of Betelgeuse in order to highlight the value of historical observations for understanding astrophysical phenomena.


Author(s):  
W. A. Chiou ◽  
N. Kohyama ◽  
B. Little ◽  
P. Wagner ◽  
M. Meshii

The corrosion of copper and copper alloys in a marine environment is of great concern because of their widespread use in heat exchangers and steam condensers in which natural seawater is the coolant. It has become increasingly evident that microorganisms play an important role in the corrosion of a number of metals and alloys under a variety of environments. For the past 15 years the use of SEM has proven to be useful in studying biofilms and spatial relationships between bacteria and localized corrosion of metals. Little information, however, has been obtained using TEM capitalizing on its higher spacial resolution and the transmission observation of interfaces. The research presented herein is the first step of this new approach in studying the corrosion with biological influence in pure copper.Commercially produced copper (Cu, 99%) foils of approximately 120 μm thick exposed to a copper-tolerant marine bacterium, Oceanospirillum, and an abiotic culture medium were subsampled (1 cm × 1 cm) for this study along with unexposed control samples.


2018 ◽  
Author(s):  
Gaolei Zhan ◽  
Younes Makoudi ◽  
Judicael Jeannoutot ◽  
Simon Lamare ◽  
Michel Féron ◽  
...  

Over the past decade, on-surface fabrication of organic nanostructures has been widely investigated for the development of molecular electronic devices, nanomachines, and new materials. Here, we introduce a new strategy to obtain alkyl oligomers in a controlled manner using on-surface radical oligomerisations that are triggered by the electrons/holes between the sample surface and the tip of a scanning tunnelling microscope. The resulting radical-mediated mechanism is substantiated by a detailed theoretical study. This electron transfer event only occurs when <i>V</i><sub>s</sub> < -3 V or <i>V</i><sub>s</sub> > + 3 V and allows access to reactive radical species under exceptionally mild conditions. This transfer can effectively ‘switch on’ a sequence leading to formation of oligomers of defined size distribution due to the on-surface confinement of reactive species. Our approach enables new ways to initiate and control radical oligomerisations with tunnelling electrons, leading to molecularly precise nanofabrication.


2018 ◽  
Vol 25 (5) ◽  
pp. 636-658 ◽  
Author(s):  
Jan Pokorny ◽  
Lucie Borkova ◽  
Milan Urban

Triterpenoids are natural compounds with a large variety of biological activities such as anticancer, antiviral, antibacterial, antifungal, antiparazitic, antiinflammatory and others. Despite their low toxicity and simple availability from the natural resources, their clinical use is still severely limited by their higher IC50 and worse pharmacological properties than in the currently used therapeutics. This fact encouraged a number of researchers to develop new terpenic derivatives more suitable for the potential clinical use. This review summarizes a new approach to improve both, the activity and ADME-Tox properties by connecting active terpenes to another modifying molecules using click reactions. Within the past few years, this synthetic approach was well explored yielding a lot of great improvements of the parent compounds along with some less successful attempts. A large quantity of the new compounds presented here are superior in both activity and ADME-Tox properties to their parents. This review should serve the researchers who need to promote their hit triterpenic structures towards their clinical use and it is intended as a guide for the chemical synthesis of better drug candidates.


How was history written in Europe and Asia between 400–1400? How was the past understood in religious, social, and political terms? And in what ways does the diversity of historical writing in this period mask underlying commonalities in narrating the past? The volume tackles these and other questions. Part I provides comprehensive overviews of the development of historical writing in societies that range from the Korean Peninsula to north-west Europe, which together highlight regional and cultural distinctiveness. Part II complements the first part by taking a thematic and comparative approach; it includes chapters on genre, warfare, and religion (amongst others) which address common concerns of historians working in this liminal period before the globalizing forces of the early modern world.


The Oxford Handbook of American Women’s and Gender History boldly interprets the history of diverse women and how ideas about gender shaped their access to political and cultural power in North America over six centuries. In twenty-nine chapters, the Handbook showcases women’s and gender history as an integrated field with its own interpretation of the past, focused on how gender influenced people’s lives as they participated in migration, colonialism, trade, warfare, artistic production, and community building. Organized chronologically and thematically, the Handbook’s six sections allow readers to consider historical continuities of gendered power as well as individual innovations and ruptures in gender systems. Theoretically cutting edge, each chapter bursts with fascinating historical characters, from young Chicanas transforming urban culture, to free women of color forging abolitionist doctrines, to Asian migrant women defending the legitimacy of their marriages, to working-class activists mobilizing international movements, to transwomen fleeing incarceration. Together, their lives constitute the history of a continent. Leading scholars from multiple generations demonstrate the power of innovative research to excavate a history hidden in plain sight. Scrutinizing silences in the historical record, from the inattention to enslaved women’s opinions to the suppression of Indian women’s involvement in border diplomacy, the authors challenge the nature of historical evidence and remap what counts in our interpretation of the past. They demonstrate a way to extend this more capacious vision of history forward, setting an intellectual agenda informed by intersectionality and transnationalism, and new understandings of sexuality.


Traditio ◽  
2018 ◽  
Vol 73 ◽  
pp. 83-116
Author(s):  
PETER O'HAGAN

Peter Lombard's influential commentary on the Pauline Epistles, theCollectanea in omnes divi Pauli epistolas,has received little extended analysis in scholarly literature, despite its recognized importance both in its own right and as key for the development of hisSentences.This article presents a new approach to studying theCollectaneaby analyzing how Lombard's commentary builds on theGlossa “Ordinaria”on the Pauline Epistles. The article argues for treating theCollectaneaas a “historical act,” focusing on how Lombard engages with the biblical text and with authoritative sources within which he encounters the same biblical text embedded. The article further argues for the necessity of turning to the manuscripts of both theCollectaneaand theGlossa,rather than continuing to rely on inadequate early modern printed editions or thePatrologia Latina.The article then uses Lombard's discussion of faith at Romans 1:17 as a case study, demonstrating the way in which Lombard begins from theGlossa,clarifies its ambiguities, and moves his analysis forward through his use of otherauctoritatesand theologicalquaestiones.A comparison with Lombard's treatment of faith in theSentenceshighlights the close links between Lombard's biblical lectures and this later work. The article concludes by arguing that scholastic biblical exegesis and theology should be treated as primarily a classroom activity, with the glossed Bible as the central focus. Discussion of Lombard's work should draw on much recent scholarship that has begun to uncover the layers of orality within the textual history of scholastic works.


2007 ◽  
Vol 23 (1) ◽  
pp. 49-57 ◽  
Author(s):  
Christian M. Billing

In this article Christian M. Billing considers the relationship between female lament and acts of vengeance in fifth-century Athenian society and its theatre, with particular emphasis on the Hekabe of Euripides. He uses historical evidence to argue that female mourning was held to be a powerfully transgressive force in the classical period; that considerable social tensions existed as a result of the suppression of female roles in traditional funerary practices (social control arising from the move towards democracy and the development of forensic processes as a means of social redress); and that as a piece of transvestite theatre, authored and performed by men to an audience made up largely, if not entirely, of that sex, Euripides' Hekabe demonstrates significant gender-related anxiety regarding the supposedly horrific consequences of allowing women to speak at burials, or to engage in lament as part of uncontrolled funerary ritual. Christian M. Billing is an academic and theatre practitioner working in the fields of ancient Athenian and early modern English and European drama. He has worked extensively as a director and actor and has also taught at a number of universities in the United Kingdom and the USA. He is currently Lecturer in Drama at the University of Hull.


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