scholarly journals Molecular evolution of lineage 2 West Nile virus

2013 ◽  
Vol 94 (2) ◽  
pp. 318-325 ◽  
Author(s):  
Allison R. McMullen ◽  
Harun Albayrak ◽  
Fiona J. May ◽  
C. Todd Davis ◽  
David W. C. Beasley ◽  
...  

Since the 1990s West Nile virus (WNV) has become an increasingly important public health problem and the cause of outbreaks of neurological disease. Genetic analyses have identified multiple lineages with many studies focusing on lineage 1 due to its emergence in New York in 1999 and its neuroinvasive phenotype. Until recently, viruses in lineage 2 were not thought to be of public health importance due to few outbreaks of disease being associated with viruses in this lineage. However, recent epidemics of lineage 2 in Europe (Greece and Italy) and Russia have shown the increasing importance of this lineage. There are very few genetic studies examining isolates belonging to lineage 2. We have sequenced the full-length genomes of four older lineage 2 WNV isolates, compared them to 12 previously published genomic sequences and examined the evolution of this lineage. Our studies show that this lineage has evolved over the past 300–400 years and appears to correlate with a change from mouse attenuated to virulent phenotype based on previous studies by our group. This evolution mirrors that which is seen in lineage 1 isolates, which have also evolved to a virulent phenotype over the same period of time.

2013 ◽  
Vol 141 (11) ◽  
pp. 2313-2316 ◽  
Author(s):  
G. SAVINI ◽  
G. PUGGIONI ◽  
A. DI GENNARO ◽  
G. DI FRANCESCO ◽  
A. M. ROCCHIGIANI ◽  
...  

SUMMARYWest Nile virus (WNV) strains belonging to lineage 2 were detected and isolated from the tissues of a goshawk and two carrion crows in Sardinia in August 2012. According to NS3 sequence analysis, the Sardinian isolates shared a high level of similarity with those of Italian lineage 2 strains which circulated in 2011 and with the homologous sequence of the 2004 Hungarian isolate. Following the human fatality reported in 2011 in Olbia, this study is the first to report the spread and enzootic circulation of WNV lineage 2 in Sardinia.


2019 ◽  
Vol 7 (8) ◽  
pp. 166-174
Author(s):  
Seifu Lemma ◽  
Abeyenh Leza ◽  
Gimete Gercha ◽  
Alemayeh Radii

Brucellosis is a contagious bacterial disease with worldwide importance and affects a number of animal species and human beings. Although brucellosis in domestic animals has controlled in most developed countries it remains an important public health problem in several parts of the world. But in developing countries brucellosis has both animal and public health importance (Walker, 1999; Radostitset al.,2000; Acha, and Szyfers, 2001; Tsolia et al.,2002).


2021 ◽  
Vol 6 (4) ◽  
pp. 176
Author(s):  
Stavroula Beleri ◽  
Georgios Balatsos ◽  
Vasilios Karras ◽  
Nikolaos Tegos ◽  
Fani Sereti ◽  
...  

Seasonal patterns of mosquito population density and their vectorial capacity constitute major elements to understand the epidemiology of mosquito-borne diseases. Using adult mosquito traps, we compared the population dynamics of major mosquito species (Culex pipiens, Aedes albopictus, Anopheles spp.) in an urban and a wetland rural area of Attica Greece. Pools of the captured Cx. pipiens were analyzed to determine infection rates of the West Nile virus (WNV) and the Usutu virus (USUV). The data provided were collected under the frame of the surveillance program carried out in two regional units (RUs) of the Attica region (East Attica and South Sector of Attica), during the period 2017–2018. The entomological surveillance of adult mosquitoes was performed on a weekly basis using a network of BG-sentinel traps (BGs), baited with CO2 and BG-Lure, in selected, fixed sampling sites. A total of 46,726 adult mosquitoes were collected, with larger variety and number of species in East Attica (n = 37,810), followed by the South Sector of Attica (n = 8916). The collected mosquitoes were morphologically identified to species level and evaluated for their public health importance. Collected Cx. pipiens adults were pooled and tested for West Nile virus (WNV) and Usutu virus (USUV) presence by implementation of a targeted molecular methodology (real-time PCR). A total of 366 mosquito pools were analyzed for WNV and USUV, respectively, and 38 (10.4%) positive samples were recorded for WNV, while no positive pool was detected for USUV. The majority of positive samples for WNV were detected in the East Attica region, followed by the South Sector of Attica, respectively. The findings of the current study highlight the WNV circulation in the region of Attica and the concomitant risk for the country, rendering mosquito surveillance actions and integrated mosquito management programs as imperative public health interventions.


2021 ◽  
Vol 5 (2) ◽  
pp. 151-157
Author(s):  
Muktar A. Gadanya ◽  
Imrana A. Buhari

Environmental pollution is the most important public health problem densely in populated areas in the developing countries and often the underlying cause of many diseases of public health importance. Noise pollution is an undesirable sound that interferes with wellbeing in the environment with significant effects. With the current rapid growth and technological advancement, noise pollution is increasingly becoming environmental menace that deserves appropriate attention in order to  mitigate its health effects. This paper aims to determine the sources, awareness and health effects of noise pollution in a typical Nigerian sub-urban population. Descriptive cross-sectional study using interviewer administered questionnaire and measurement of environmental noise using acoustic metre. Majority of the respondents (75.8%) were exposed to noise levels above the 55dB WHO safe noise level without health effects. Power generators, automobiles and grinding machines are the commonest sources of noise pollution in the studied environment amounted to a value of 55.8%, 40% and 35.8% respectively and to a lesser extent hawker (16.4%) and loudspeaker (9.6%) among others. Sleep disturbance, headache, and poor concentration were commonly reported effects of noise in the environment with magnitudes of 52.7%, 50.9%, 15.8% respectively. Anxiety (12.1%) and hearing disturbances (11.5%) were also common. Noise pollution associated health problems are common in the community with significant effects on the quality of life of the inhabitants. Stable power supply, effective legislation and improvement in living condition of the people are key to minimize noise pollution and avert its deleterious health effects


2021 ◽  
Vol 5 (2) ◽  
pp. 52-58
Author(s):  
Muktar A. Gadanya ◽  
Imrana A. Buhari

Environmental pollution is the most important public health problem densely in populated areas in the developing countries and often the underlying cause of many diseases of public health importance. Noise pollution is an undesirable sound that interferes with wellbeing in the environment with significant effects. With the current rapid growth and technological advancement, noise pollution is increasingly becoming environmental menace that deserves appropriate attention in order to mitigate its health effects. This paper aims to determine the sources, awareness and health effects of noise pollution in a typical Nigerian sub-urban population. Descriptive cross-sectional study using interviewer administered questionnaire and measurement of environmental noise using acoustic metre. Majority of the respondents (75.8%) were exposed to noise levels above the 55dB WHO safe noise level without health effects. Power generators, automobiles and grinding machines are the commonest sources of noise pollution in the studied environment amounted to a value of 55.8%, 40% and 35.8% respectively and to a lesser extent hawker (16.4%) and loudspeaker (9.6%) among others. Sleep disturbance, headache, and poor concentration were commonly reported effects of noise in the environment with magnitudes of 52.7%, 50.9%, 15.8% respectively. Anxiety (12.1%) and hearing disturbances (11.5%) were also common. Noise pollution associated health problems are common in the community with significant effects on the quality of life of the inhabitants. Stable power supply, effective legislation and improvement in living condition of the people are key to minimize noise pollution and avert its deleterious health effects.


2020 ◽  
Vol 63 (12) ◽  
pp. 477-482
Author(s):  
Maximilian Andreas Storz

The childhood obesity pandemic has emerged as an important public health problem in many countries. Obese children are likely to become obese adults, and adult obesity is associated with an increased risk of morbidity. Therefore, controlling the childhood obesity epidemic has become a top public health priority worldwide. The current coronavirus disease 2019 (COVID-19) pandemic may significantly impede this important mission and constitute an unprecedented tragedy in the global battle against childhood obesity. This manuscript presents evidence that the COVID-19 pandemic will aggravate the childhood obesity epidemic and lead to significant weight gain in school children by creating an unprecedented obesogenic environment. Within the last few months, many countries took uncompromising measures in response to the COVID-19 pandemic, including school closures and quarantine. While these steps are often necessary to ensure infection control, they may have a significant negative effect on children's mental and physical health. Physical, nutritional, and psychosocial factors that promote obesity in children during this special situation complementarily contribute to an unprecedented obesogenic environment. Large-scale quarantine and home confinement will impose new and unfamiliar stressors on children, thereby worsening the childhood obesity epidemic. Most importantly, adverse childhood events resulting from a predicted increase in domestic violence within the next few months will significantly contribute to this concern. The scenario presented in this review is of paramount public health importance and must be considered during future pandemic planning. Involved stakeholders, including governments, schools, and families, must make all possible efforts to minimize the impact of the COVID-19 epidemic on childhood obesity.


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