scholarly journals Determinants of Internet Addiction among Adolescents: A Case-Control Study

2011 ◽  
Vol 11 ◽  
pp. 866-874 ◽  
Author(s):  
Artemis Tsitsika ◽  
Elena Critselis ◽  
Amalia Louizou ◽  
Mari Janikian ◽  
Aliki Freskou ◽  
...  
Keyword(s):  
Academic Performance ◽  
High Risk ◽  
Risk Behaviors ◽  
Internet Addiction ◽  
Case Control Study ◽  
Case Control ◽  
Case Group ◽  
High Risk Behaviors ◽  
Poor Academic Performance ◽  
Control Study

Internet Addiction (IA) is associated with adverse psychosocial development and mental disorders. The study aims were to evaluate the psychosocial profiles and psychiatric comorbidities associated with IA among adolescents. A case-control study was conducted among 129 adolescents in the outpatient setting of the Adolescent Health Unit of the Second University Department of Pediatrics in Athens, Greece. The case group consisted of 86 adolescents with IA as evaluated following psychiatric interview with two independent examiners. The control group consisted of 43 adolescents without IA, frequency matched for age and gender with case group participants. The study findings indicated that adolescents with IA were significantly more likely to have divorced parents (p= 0.012) and/or dysfunctional familial relationships (p< 0.0001). The proportion of adolescents with poor academic performance (p< 0.0001) and unexcused school absences (p= 0.004) was greater among those with IA. Moreover, approximately two-thirds of the adolescents with IA were engaged in high-risk behaviors (p< 0.0001). Finally, adolescents with IA were 3.89 times more likely to present with comorbid psychiatric conditions (CI 95%: 1.19–12.70), including depression (10.5 vs. 0%;p= 0.022). Adolescent IA is associated with deterred familial functions, poor academic performance, engagement in high-risk behaviors, and an augmented likelihood for depression.

Does Placental Weight Affects Perinatal Outcome? A Prospective Case-control Study

2020 ◽  
Vol 16 (1) ◽  
pp. 52-59
Author(s):  
Naina Kumar ◽  
Himani Agarwal
Keyword(s):  
Birth Weight ◽  
High Risk ◽  
Perinatal Outcome ◽  
Case Control Study ◽  
Neonatal Outcome ◽  
Case Control ◽  
Placental Weight ◽  
Tertiary Center ◽  
Control Study ◽  
Prospective Case Control Study

Background: Placenta plays a very important role in the growth and development of fetus. Objective: To know the correlation between placental weight and perinatal outcome in term antenatal women. Methods: Present prospective case-control study was conducted in the rural tertiary center of Northern India over one year (January-December 2018) on 1,118 term (≥37-≤42 weeks) antenatal women with singleton pregnancy fulfilling inclusion criteria with 559 women with high-risk pregnancy as cases and 559 low-risk pregnant women as controls. Placental weight, birth weight was measured immediately after delivery and compared between the two groups along with gestation, parity, fetal gender, and neonatal outcome. Statistical analysis was done using SPSS 22 version. Results: Mean placental weight [481.98±67.83 gm vs. 499.47±59.59 gm (p=.000)] and birth weight [2.68±0.53 Kg vs. 2.88±0.4 Kg (p=.000)] was significantly lower in high risk as compared to lowrisk participants, whereas placental birth weight ratio was higher in high-risk cases [18.35±2.37 vs. 17.41±1.38 (p=.000)] respectively. Placental weight was positively correlated with birth weight and placental weight and birth weight increased with increasing gestation in both cases and controls. Male neonates had higher placental weight [492.74±68.24 gm vs. 488±58.8 gm (p=0.224)] and birth weight [2.81±0.5 Kg vs. 2.74±0.45 Kg (p=0.033)] as compared to females. Neonatal Intensive Care Unit admission was significantly associated with low placental and birth weight (p=.000). Conclusion: There is a significant correlation between placental weight, birth weight and neonatal outcome, hence placental weight can be used as an indirect indicator of intrauterine fetal growth.

scholarly journals The predictor role of Internet addiction in high- risk behaviors and general health status among Alborz students: A structural equation model

Heliyon ◽  
2021 ◽  
Vol 7 (5) ◽  
pp. e06987
Author(s):  
Azam Toozandehjani ◽  
Zohreh Mahmoodi ◽  
Mitra Rahimzadeh ◽  
Alireza Jashni Motlagh ◽  
Mahnaz Akbari Kamrani ◽  
...  
Keyword(s):  
Health Status ◽  
High Risk ◽  
Risk Behaviors ◽  
Structural Equation Model ◽  
Internet Addiction ◽  
Structural Equation ◽  
Equation Model ◽  
General Health Status ◽  
High Risk Behaviors

scholarly journals Associations between Red Blood Cell and Platelet Transfusions and Retinopathy of Prematurity

Neonatology ◽  
2020 ◽  
pp. 1-7
Author(s):  
Tobias Hengartner ◽  
Mark Adams ◽  
Riccardo E. Pfister ◽  
Diane Snyers ◽  
Jane McDougall ◽  
...  
Keyword(s):  
Retinopathy Of Prematurity ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Same Sex ◽  
Live Births ◽  
Adjusted Logistic Regression ◽  
Control Study

<b><i>Aim:</i></b> The aim of this study is to examine possible associations between the transfusion of RBC or platelets (PLTs) and the development of retinopathy of prematurity (ROP) in infants. <b><i>Methods:</i></b> This retrospective, national, case-control study included all live births in Switzerland between 2013 and 2018. We investigated preterm infants at a gestational age of &#x3c;28 weeks, who developed higher stage ROP (≥stage 2, <i>n</i> = 178). Each case infant was matched to another of the same sex who did not develop ROP (<i>n</i> = 178, control group). <b><i>Results:</i></b> When compared with the control group, we observed higher numbers of RBC transfusions per infant and higher percentages of infants receiving PLT transfusions in the case group. An adjusted logistic regression analysis revealed that both RBC (odds ratio [OR] 1.081, 95% confidence interval [CI] 1.020–1.146) and PLT transfusions (OR = 2.502, 95% CI 1.566–3.998) numbers were associated with ROP development. <b><i>Conclusions:</i></b> Multiple RBC and PLT transfusions are associated with higher stage ROP development. Prospective studies are required to determine their potential as risk factors.

scholarly journals The role of leukotriene modifying agent treatment in neuropsychiatric events of elderly asthma patients: a nested case control study

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Sang Oh Kang ◽  
Kyung Hyun Min ◽  
Hyun Jeong Kim ◽  
Tae Hyeok Kim ◽  
Woorim Kim ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Boxed Warning ◽  
Control Group ◽  
Case Group ◽  
Newly Diagnosed ◽  
Crude Odds Ratio ◽  
Asthma Patients ◽  
Nested Case Control ◽  
Control Study

Abstract Background In March 2020, the US Food and Drug Administration decided that the dangers related to neuropsychiatric events (NPEs) of montelukast, one of the leukotriene modifying agents (LTMAs), should be communicated through ‘boxed warning’. In case of NPEs, the prevalence has been the highest in elderly people. Because the characteristics of the elderly such as old age itself can act as risk factors. Therefore, an investigation on safety of LTMAs related to NPEs in elderly using LTMAs is needed. Method A nested case-control study using an elderly sample cohort from the Korean National Health Insurance Service database was used. The asthma cohort included asthma patients newly diagnosed between 2003 and 2013. Within the asthma cohort, the case group was defined as patients who were diagnosed with NPEs. Among patients who had never been diagnosed with NPEs, the control group was selected by matching 1:1 by propensity score. Patients who were prescribed LTMAs for 1 year prior to index date were defined as the exposure group. The logistic regression model was used to measure the effect of LTMAs on NPEs. Results We identified 141,165 patients with newly diagnosed asthma, and selected 31,992 patients per each case and control group. Exposure to LTMAs significantly increased the risk of overall NPEs about in comparison with the absence of exposure (crude odds ratio [OR] 1.58, 95% CI 1.50–1.68). After adjusting for confounding factors, the overall NPEs risk increased (adjusted OR, 1.67, 95% CI 1.58–1.78). Conclusion This study suggests that elderly asthma patients prescribed LTMAs had a higher risk of NPEs than patients who were not treated with LTMAs. Therefore, clinicians should be aware of the potential risks of LTMAs.

scholarly journals Risk factors of acute diarrhoea in summer – a nation-wide French case-control study

2000 ◽  
Vol 124 (3) ◽  
pp. 409-416 ◽  
Author(s):  
Y. YAZDANPANAH ◽  
L. BEAUGERIE ◽  
P. Y. BOËLLE ◽  
L. LETRILLIART ◽  
J. C. DESENCLOS ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Case Control Study ◽  
National Level ◽  
Acute Diarrhoea ◽  
Case Control ◽  
French Case ◽  
Risk Areas ◽  
Matched Case ◽  
Control Study

The aim of this study was to identify risk factors for acute diarrhoea (AD) during the summer in France. A matched case-control study was conducted at a national level among patients of 500 general practitioners (GPs). From July to September 1996, 468 case-control pairs were included. Cases were more likely than controls (i) to live away from their main residence (OR 3·0; 95% CI 1·6–5·7), (ii) to have returned from a country at high risk of AD (OR 4·6; CI 0·9–23·1), and (iii) to have been in contact with a case of AD (OR 2·0; CI 1·3–3·1). A significantly decreased risk of AD was found for consumption of well-cooked chicken (OR 0·5; CI 0·3–0·8) and raw or undercooked home-made egg-containing products (OR 0·6; CI 0·4–0·8). These findings suggest that travel to high-risk areas, or travel within France, and being in contact with a case of AD, are risk factors for the occurrence of AD in summer in France.

Twenty-one-gene recurrence score (RS) in germline (g)CHEK2 mutation-associated versus sporadic breast cancers (BC): A multi-site case-control study.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 10531-10531
Author(s):  
Anosheh Afghahi ◽  
Sydney Marsh ◽  
Alyse Winchester ◽  
Dexiang Gao ◽  
Hannah Parris ◽  
...  
Keyword(s):  
Lymph Node ◽  
Genetic Testing ◽  
High Risk ◽  
Case Control Study ◽  
Case Control ◽  
Low Risk ◽  
Mutation Status ◽  
T Stage ◽  
Chek2 Mutation ◽  
Control Study

10531 Background: Genomic assays, such as RS, are used to determine chemotherapy benefit in early-stage, estrogen receptor (ER)- and/or progesterone receptor (PR)-positive, HER2 negative BC patients (pts). Currently, guidelines to use pts’ germline genetic testing results to guide adjuvant therapy are lacking. Several reports have indicated worse outcomes for BC pts with g CHEK2 pathogenic variants (PV). We investigated whether PV in CHEK2 were associated with increased RS. Methods: Patient-level clinical data and RS were derived from electronic medical records of seven medical centers between years 2013-17. Confirmation of RS using the Genomic Health provider portal was performed. 38 pts with germline PV in CHEK2 (15 pts/39.5% with c.1100delC mutation) and RS score (cases) were matched with BC pts whose genetic testing did not identify PV (controls) using a 1:2 matching schema. Pts were matched based on age at diagnosis and lymph node (LN) status. LN negative pts were further matched based on T-stage. A multivariate random intercept linear mixed model of CHEK2 mutation status on RS was performed, adjusting for PR. A secondary ordinal univariate analysis was conducted that categorized RS into low, intermediate and high risk ( < 18, 18-30, and > 30, respectively). P-values were reported based on a null hypothesis of no effect against a two-sided alternative. Results: The median RS for cases was 19.5 (interquartile range [IQR]: 15 to 25) and the median RS for controls was 18 (IQR: 12 to 22). A greater proportion of cases were categorized as high risk (10.5%) compared to controls (5.6%), and a smaller proportion of cases were categorized as low risk (36.8%) compared to controls (49.3%). Cases had higher grade and increased proportion of PR-negative BC as compared with controls (grade 1: 12.1% of cases versus 32.4% of controls; PR-negative: 7.9% of cases versus 5.6% of controls). The variables used to match cases and controls (age, lymph node status, and T-stage) had similar summary statistics. The RS was 1.97-point higher in pts with g CHEK2 PV compared to controls, after adjusting for PR (95% confidence interval [CI]: 1.02-point lower to 4.96-point higher; p = 0.194). The secondary analysis of CHEK2 mutation status on an ordinal RS risk group yielded comparable results; on average, the odds of being high risk compared to the combined intermediate/low risk groups was 1.72 times higher in cases compared to controls (95% CI: 0.77 to 3.80; p = 0.181), but these differences were not significant. Conclusions: Our case-control study did not show a statistically higher RS for BC that develops in pts with g CHEK2 PV. Further studies are warranted to evaluate the association between type of CHEK2 PV (frameshift versus missense) and other modifying genetic variables and RS.

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